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Carbon resonances of pyrrole acids, e.g. 1 and 2, fall within the following ranges: α-COOH: δ 160-162; COOH-bearing α-carbons: δ 120-122; β-COOH: δ 165-167; COOH-bearing β-carbons: δ 113-116
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Carbon resonances of pyrrole acids, e.g. 1 and 2, fall within the following ranges: α-COOH: δ 160-162; COOH-bearing α-carbons: δ 120-122; β-COOH: δ 165-167; COOH-bearing β-carbons: δ 113-116.
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16
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85030200137
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note
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1H NMR data do not match at all with those of the product isolated in the present study. We suspect that the product synthesised by the previous authors and claimed to be 4 was in fact an isomer, possibly 2-carboxymethylpyrrole-3,4-dicarboxylic acid. This would also provide a plausible explanation of why the product could not be detected by the previous workers 11 in the oxidation of eumelanins, in spite of very careful experiments.
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