Solvent exposed side chains of peptides bound to HLA A*1101 have similar effects on the reactivity of alloantibodies and specific TCR

International Immunology

Volumn 8, Issue 6, 1996, Pages 927-938

  Zhang, Qian Jin ^a   Lindquist, Ylva ^b   Levitsky, Victor ^a   Masucci, Maria G ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Cytotoxic T lymphocyte; HLA A*1101; Molecular model; Peptide

Indexed keywords

ALLOANTIBODY; HLA A ANTIGEN; T LYMPHOCYTE RECEPTOR;

ALLOIMMUNITY; ANTIGEN PRESENTATION; ANTIGEN RECOGNITION; ARTICLE; CYTOTOXIC T LYMPHOCYTE; EPSTEIN BARR VIRUS; HLA SYSTEM; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

ANTIBODIES, MONOCLONAL; ANTIGEN-ANTIBODY REACTIONS; ATP-BINDING CASSETTE TRANSPORTERS; CELL LINE, TRANSFORMED; HLA-A ANTIGENS; HUMANS; ISOANTIBODIES; MODELS, MOLECULAR; PEPTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, ANTIGEN, T-CELL; SOLVENTS; T-LYMPHOCYTES, CYTOTOXIC;

EID: 0029890069     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/8.6.927     Document Type: Article

References (51)

1. Townsend, A. R. M., Rothbard, J., Gotch, F. M., Bahadur, G., Wraith, D. and McMichael, A. J. 1986. The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides. Cell 44:959.
2. Björkman, P. J., Saper, M. A., Samraoui, B., Bennett, W. S., Strominger, J. L. and Wiley, D. C. 1987. The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens. Nature 54:512.
3. Garret, T., Saper, M., Bjorkman, P., Strominger, J. and Wiley, D. 1989. Specificity pockets for the side chains of peptide antigens in HLA Aw68. Nature 342:692.
4. Falk, K., Rötzschke, O , Stevanovic, S., Jung, G. and Rammensee, H.-G. 1991. Allele-specific motifs revealed by sequencing of selfpeptides eluted from MHC molecules. Nature 351:290.
5. Jardetzky, T., Lane, W., Robinson, R., Madden, D. and Wiley, D. 1991. Identification of self peptides bound to purified HLA-B27. Nature 353:326.
6. Madden, D. R., Gorga, J. C., Strominger, J. L. and Wiley, D. C. 1991. The structure of HLA-B27 reveals nonamer self-peptides bound in an extended conformation. Nature 353:321.
7. Catipovic, B., Dal, P. J., Mage, M., Johansen, T. E. and Schneck, J. P. 1992, Major histocompatibility complex conformational epitopes are peptide specific. J. Exp. Med. 176:1611.
8. Hogquist. K. A., Grandea, A. G. I. and Bevan, M. J. 1993. Peptide variants reveal how antibodies recognize major histocompatibility complex class I. Eur. J. Immunol. 23:3028.
9. Fukazawa, T., Wang J., Huang. F., Wen, J., Tyan, D., Williams, K. M., Raybourne, R. B. and Yu, D. T. 1994. Testing the importance of each residue in a HLA-B27-binding peptide using monoclonal antibodies. J. Immunol 152:1190
10. Wang, J., Yu, D, T., Fukazawa, T., Kellner, H., Wen, J., Cheng, X. K., Roth, G., Williams, K M. and Raybourne, R. B. 1994. A monoclonal antibody that recognizes HLA-B27 in the context of peptides. J. Immunol. 152:1197
11. Rohren, E. M., McCormick D J. and Pease, L. R. 1994, Peptide-induced conformational changes in class I molecules. Direct detection by flow cytometry. J. Immunol. 152:5337.
12. Sherman, L. A., Chattopadhyay, S., Biggs, J. A., Dick, R. F. I. and Bluestone, J. A. 1993. Alloantibodies can discriminate class I major histocompatibility complex molecules associated with various endogenous peptides, Proc. Natl Acad. Sci. USA 90:6949.
13. Barouch, D., Davenport, M., A., M. and Reay, P. 1995. A mAb against HLA-A2 can be influenced both positively and negatively by the associated peptide. Int. Immumol. 7:1599.
14. Madden, D. R., Garboczi, D. N. and Wiley, D. C. 1993. The antigenic identity of peptide-MHC complexes: a comparison of the conformations of five viral peptides presented by HLA-A2. Cell 75:693.
15. Solheim, J. C., Carreno, B. M., Smith, J. D., Gorka, J., Myers, N. B., Wen, Z., Martinko, J. M., Lee, D. R. and Hansen, T. H. 1993. Binding of peptides lacking consensus anchor residue alters H-2Lc serologic recognition. J. Immunol. 151:5387.
16. Solheim, J. C., Carreno, B. M., Myers, N. B., Lee, D. R. and Hansen. T. H. 1995. Peptide-induced rescue of serologic epitopes on class I MHC molecules. J Immunol. 154:1188.
17. Salter, R. and Cresswell, P. 1986. Impaired assembly and transport of HLA-A and -B antigens in a mutant TxB cell hybrid. EMBO. J. 5:943.
18. Kelly, A., Powis, S. H., Kerr, L. A., Mockridge, L., Elliott, T, Bastin, J., Uchanska-Ziegler, B., Ziegler, A., Trowsdale, J. and Townsend, A. 1992. Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex. Nature 355:641.
19. Zhang, Q. J., Gavioli, R., Klein, G. and Masucci, M. G. 1993. An HLA-A11-specific motif in nonamer peptides derived from viral and cellular proteins. Proc. Natl Acad. Sci. USA 90:2217.
20. Miller, G. and Lipman, M. 1973. Release of infectious Epstein-Barr virus by transformed marmoset leukocytes. Proc. Natl Acad. Sci. USA 70:190.
21. Hirs, C. H. W. and Timasheff, S. 1977. Enzyme Structure, vol XVII. Academic Press, New York.
22. Dumas, B. 1975. Standards for total serum protein assays, a collaborative study. Clin. Chem. 21:1159.
23. de Campos-Lima, P. O., Levitsky, V., Brooks, J., Lee, S. P., Hu, L. F., Rickinson, A. B. and Masucci, M. G. 1994. T cell responses and virus evolution: Epstein-Barr virus isolates from highly HLA A11-positive populations carry mutations selectively involving anchor residues of A11-restricted CTL epitopes J Exp. Med. 179:1297.
24. Baer, R., Bankier, A. T., Biggin, M. D., Deininger, P. L., Farrell, P. J., Gibson, T. J., Hatfull, G., Hudson, G. S., Satchwell, S. C., Seguin, C., et al. 1984. DNA sequence and expression of the B95-8 Epstein-Barr virus genome. Nature 310:207.
25. Seedorf, K., Krammer, G., Durst, M., Suhai, S. and Rowekamp, W. G. 1985. Human papillomavirus type 16 DNA sequence. Virology 145:181.
26. Phelps, W. C., Yee, C. L.. Munger, K. and Howley. P. M. 1988. The human papillomavirus type 16 E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A. Cell 53:539.
27. Cole, S. T. and Danos, O. 1987. Nucleotide sequence and comparative analysis of the human papillomavirus type 18 genome. Phylogeny of papillomavirus and repeated structure of the E6 and E7 gene products. J. Mol. Biol. 193:599.
28. Ratner, L., Haseltine, W., Patarca, R., Livak. K. J., Starcich, B., Josephs, S. F., Doran, E. R., Rafalski, J. A., Whitehorn, E. A., Baumeister, K., et al. 1985. Complete nucleotide sequence of the AIDS virus, HTLV-III. Nature 313:277.
29. Soussi, T., de Fromentel, C. C. and May, P. 1990. Structural aspects of the p53 protein in relation to gene evolution. Oncogene 5:945.
30. Kan, C. C., Solomon, E., Belt, K. T., Chain, A. C., Hiorns. L. R. and Fey, G. 1985. Nucleotide sequence of cDNA encoding human alpha 2-macroglobulin and assignment of the chromosomal locus. Proc. Natl Acad. Sci. USA 82:2282.
31. Gorlin, J. B., Yamin, R., Egan, S., Stewart, M., Stossel, T. P., Kwiatkowski, D. J. and Hartwig, J. H. 1990. Human endothelial actin-binding protein (ABP-280, nonrnuscle filamin): a molecular leaf spring. J. Cell Biol. 111:1089.
32. Barnstable, C., Bodmer, W., Brown, G., Galfre, G., Milstein, C., Williams, A. and Ziegler, A. 1978. Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens - new tools for genetic analysis. Cell 14:9.
33. Colombani, J., Dausset, J., Lepage, V., Degos, L., Kalil, J. and Fellous, M. 1982 HLA monoclonal antibody registry: a proposal. Tissue Antigens 20:161.
34. Foung, S. K., Taidi, B., Ness, D. and Grumet, F. C. 1986 A monoclonal antibody against HLA-A11 and A24. Hum. Immunol. 15:316.
35. Ge, J., Bratlie, A. and Hannestad, K. 1994. A novel HLA-A determinant recognized by a cytotoxic human hybridoma IgG1 monoclonal antibody (TrJ14). Tissue Antigens 44:306.
36. Ljunggren, H., Stam N., Öhlen, C., Neefjes, J., Höglung, P., Heenels, M., Bastin, J., Schumacher, T., Townsend, A., Kärre, K. and Ploegh, H. 1990. Empty HLA class I molecules come out in the cold. Nature 346:476.
37. Storkus, W. J., Zeh, H. 3., Maeurer, M. J., Salter, R. D. and Lotze, M. T. 1993. Identification of human melanoma peptides recognized by class I restricted tumor infiltrating T lymphocytes. J. Immunol. 151:3719.
38. Torsteinsdottir, S., Masucci, M. G., Ehlin-Henriksson, B., Brautbar, C., Ben Bassat, H., Klein, G. and Klein, E. 1986. Differentiation dependent sensitivity of human B-cell derived lines to major histocompatibility complex-restricted T-cell cytotoxicity. Proc. Natl Acad. Sci. USA 83:5620.
39. Rabin, H., Hopkins, R. F., Ruscetti, F. W., Neubawer, R. H., Brown, R. L. and Kawakami, T. G. 1981. Spontaneous release of a factor with properties of T-cell growth factor from a conlinuous line of primate tumor T cells. J. Immunol. 127:1852.
40. Jones, T. A., Zou, J., Cowan, S. W. and Kjeldaard, M. 1991. Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr. A47:110.
41. Brünger, A. T. 1992. X-PLOT Manual, version 3. 1. New Haven, CT.
42. b at 2. 4 Ångströms resolution: implications for antigen-determinant selection. Cell 76:39.
43. b: see comments. Science 257:919.
44. Collins, E. J., Garboczi, D. N. and Wiley. D. C. 1994. Three-dimensional structure of a peptide extending from one end of a class I MHC binding site. Nature 371:626.
45. Collins, E. J., Garboczi, D. N., Karpusas, M. N. and Wiley, D. C. 1995. The three-dimensional structure of a class 1 major histocompatibility complex molecule missing the alphas domain of the heavy chain. Proc. Natl Acad. Sci. USA 92:1218.
46. Madden, D. R. 1995. The three-dimensional structure of peptide-MHC complexes. Annu. Rev. Immunol. 13:587.
47. Quo, H.-C., Jardetzky, T. S., Garrett, T. P. J., Lane, W. S., Strominger, J. L. and Wiley, D. C. 1992. Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middle. Nature 360:364.
48. Wei, M and Cresswell, P. 1992. HLA A2 molecules in an antigen processing mutant cell contain signal sequence-derived peptides. Nature 356:443.
49. Sykulev, Y., Brunmark, A., Tsomides, T. J., Kageyama, S., Jackson, M., Peterson, P. A. and Eisen, H. N. 1994. High-affinity reactions between antigen-specific T-cell receptors and peptides associated with allogeneic and syngeneic major histocompatibility complex class I proteins. Proc. Natl Acad. Sci. USA 91:11487.
50. Chatopadhyay, S., Theobald, M., Biggs, J. and Sherman, L. A. 1994. Conformational differences in major histocompatibility complex-peptide complexes can result in alloreactivity. J. Exp. Med. 179:213.
51. Kraulis, P. J. 1991. MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures. J. Appl. Crystallogr. 24:946.