Glucocorticoid-remediable aldosteronism

Cardiovascular Research

Volumn 31, Issue 6, 1996, Pages 870-872

  Dluhy, Robert G ^a   Williams, Gordon H ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Glucocorticoid remediable aldosteronism

Indexed keywords

DEXAMETHASONE; GLUCOCORTICOID;

AUTOSOMAL INHERITANCE; HUMAN; HYPERALDOSTERONISM; HYPERTENSION; PRIORITY JOURNAL; SHORT SURVEY;

GLUCOCORTICOIDS; HUMANS; HYPERALDOSTERONISM; HYPERTENSION; MULTIGENE FAMILY; MUTATION;

EID: 0029889118     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/0008-6363(96)00069-7     Document Type: Short Survey

References (16)

1. Sutherland DJ, Ruse JL, Laidlaw JC. Hypertension, increased aldosterone secretion and low plasma renin activity relieved by dexamethasone. Can Med Assoc J 1966;95:1109-1119.
2. New MI, Peterson RE. A new form of congenital adrenal hyperplasia. J Clin Endocrinol Metab 1967;27:300-305.
3. Bravo E, Tarazi R, Dustan H et al. The changing clinical spectrum of primary aldosteronism. Am J Med 1983;74:641-651.
4. Gill JR, Barter FC. Overproduction of sodium-retaining steroids by the zona glomerulosa is adrenocorticotropin-dependent and mediate hypertension in dexamethasone-suppressible aldosteronism. J Clin Endocrinol Metab 1981;53:331-337.
5. Oberfield SE, Levine LS, Stoner E et al. Adrenal glomerulosa function in patients with dexamethasone-suppressible hyperaldosteronism. J Clin Endocrinol Metab 1981;53:158-164.
6. Ulick S, Chu MD, Land MI. Biosynthesis of 18-oxocortisol by aldosterone-producing adrenal tissue. 1983; J Biol Chem 258:5498-5502.
7. Gomez-Sanchez CE, Montgomery M, Ganguly A et al. Elevated urinary excretion of 18-oxocortisol in glucocorticoid-suppressible aldosteronism. J Clin Endocrinol Metab 1984;59:1022-1024.
8. Gomez-Sanchez CE, Gomez-Sanchez EP, Smith JS et al. Receptor binding and biological activity of 18-oxocortisol. Endocrinology 1985;116:6-10.
9. Rich GM, Ulick S, Cook S et al. Glucocorticoid-remediable aldosteronism in a large kindred: clinical spectrum and diagnosis using a characteristic biochemical phenotype. Ann Intern Med 1992;116:813-820.
10. c11). Proc Natl Acad Sci USA 1987; 84:7193-7197.
11. also as related to primary aldosteronism. Biochem Biophys Res Commun 1990;173:309-316.
12. 11). J Biol Chem 1989;264:20961-20967.
13. Ogishima T, Shibata H, Shimada H et al. Aldosterone synthase cytochrome P-450 expressed in the adrenals of patients with primary aldosteronism. J Biol Chem 1991;266:10731-10734.
14. Lifton RP, Dluhy RG, Powers M et al. A chimeric 11-hydroxylase/aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertension. Nature 1992;355:262-265.
15. Lifton RP, Dluhy RG, Powers M et al. Hereditary hypertension caused by chimeric gene duplications and ectopic expression of aldosterone synthase. Nature Genet 1992;2:66-74.
16. Pascoe L, Curnow KM, Slutsker L et al. Glucocorticoid-suppressible hyperaldosteronism results from hybrid genes created by unequal crossovers between CYP11B1 and CYP11B2. Proc Natl Acad Sci USA 1992;89:8327-8331.