메뉴 건너뛰기




Volumn 4, Issue 2, 1996, Pages 117-127

Photoshop-based image analysis for the semiautomated assessment of Ki-67-defined proliferative activity in the routine diagnosis of breast cancer

Author keywords

Breast cancer; Image analysis; Proliferative rate; Quantification

Indexed keywords

MONOCLONAL ANTIBODY KI 67;

EID: 0029888741     PISSN: 10623345     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (18)

References (42)
  • 1
    • 0026031529 scopus 로고
    • Treatment of early-stage breast cancer
    • NIH Consensus Conference
    • NIH Consensus Conference. Treatment of early-stage breast cancer. JAMA 1991;265:391-5.
    • (1991) JAMA , vol.265 , pp. 391-395
  • 2
    • 0026639108 scopus 로고
    • Prognostic factors and treatment decisions in axillary-node-negative breast cancer
    • McGuire WL, Clark GM. Prognostic factors and treatment decisions in axillary-node-negative breast cancer. N Engl J Med 1992;326:1756-61.
    • (1992) N Engl J Med , vol.326 , pp. 1756-1761
    • McGuire, W.L.1    Clark, G.M.2
  • 3
    • 0027217424 scopus 로고
    • Consensus review of the clinical utility of DNA cytometry in carcinoma of the breast: Report of the DNA Cytometry Consensus Conference
    • Hedley DW, Clark GM, Cornelisse CJ, Killander D, Kute T, Merkel D. Consensus review of the clinical utility of DNA cytometry in carcinoma of the breast: report of the DNA Cytometry Consensus Conference. Cytometry 1993;14: 482-5.
    • (1993) Cytometry , vol.14 , pp. 482-485
    • Hedley, D.W.1    Clark, G.M.2    Cornelisse, C.J.3    Killander, D.4    Kute, T.5    Merkel, D.6
  • 4
    • 0021885936 scopus 로고
    • The value of morphometry to classic prognosticators in breast cancer
    • Baak JP, Van-Dop H, Kurver PH, Hermans J. The value of morphometry to classic prognosticators in breast cancer. Cancer 1985;56:374-82.
    • (1985) Cancer , vol.56 , pp. 374-382
    • Baak, J.P.1    Van-Dop, H.2    Kurver, P.H.3    Hermans, J.4
  • 5
    • 0025219285 scopus 로고
    • Review: Assessment of cell proliferation in histological material
    • Hall PA, Levison DA. Review: assessment of cell proliferation in histological material. J Clin Pathol 1990;43:184-92.
    • (1990) J Clin Pathol , vol.43 , pp. 184-192
    • Hall, P.A.1    Levison, D.A.2
  • 6
    • 0025796938 scopus 로고
    • Measuring cell proliferation
    • Woosley JT. Measuring cell proliferation. Arch Pathol Lab Med 1991;115:555-7.
    • (1991) Arch Pathol Lab Med , vol.115 , pp. 555-557
    • Woosley, J.T.1
  • 7
    • 0026683110 scopus 로고
    • Clinical application of morphologic and immunocytochemical assessments of cell proliferation
    • Linden MD, Torres FX, Kubus J, Zarbo RJ. Clinical application of morphologic and immunocytochemical assessments of cell proliferation. Am J Clin Pathol 1992;97:S4-13.
    • (1992) Am J Clin Pathol , vol.97
    • Linden, M.D.1    Torres, F.X.2    Kubus, J.3    Zarbo, R.J.4
  • 8
    • 0025262148 scopus 로고
    • Indicators of prognosis in node-negative breast cancer
    • Sigurdsson H, Baldetorp B, Borg A, et al. Indicators of prognosis in node-negative breast cancer. N Engl J Med 1990; 322:1045-53.
    • (1990) N Engl J Med , vol.322 , pp. 1045-1053
    • Sigurdsson, H.1    Baldetorp, B.2    Borg, A.3
  • 9
    • 0026606157 scopus 로고
    • Prognostic significance of S-phase fraction in good-risk, node-negative breast cancer patients
    • Clark GM, Mathieu MC, Owens MA, et al. Prognostic significance of S-phase fraction in good-risk, node-negative breast cancer patients. J Clin Oncol 1992;10:428-32.
    • (1992) J Clin Oncol , vol.10 , pp. 428-432
    • Clark, G.M.1    Mathieu, M.C.2    Owens, M.A.3
  • 11
    • 0024811726 scopus 로고
    • Correlation of growth fraction by Ki-67 immunohistochemistry with histologic factors and hormone receptors in operable breast carcinoma
    • Gasparini G, Dal-Fior S, Pozza F, Bevilacqua P. Correlation of growth fraction by Ki-67 immunohistochemistry with histologic factors and hormone receptors in operable breast carcinoma. Breast Cancer Res Treat 1989;14:329-36.
    • (1989) Breast Cancer Res Treat , vol.14 , pp. 329-336
    • Gasparini, G.1    Dal-Fior, S.2    Pozza, F.3    Bevilacqua, P.4
  • 12
    • 0024369033 scopus 로고
    • Ki67 immunostaining in primary breast cancer: Pathological and clinical associations
    • Bouzubar N, Walker KJ, Griffiths K, et al. Ki67 immunostaining in primary breast cancer: pathological and clinical associations. Br J Cancer 1989;59:943-7.
    • (1989) Br J Cancer , vol.59 , pp. 943-947
    • Bouzubar, N.1    Walker, K.J.2    Griffiths, K.3
  • 14
    • 0025810796 scopus 로고
    • Immunobiochemical and molecular biologic characterization of the cell proliferation-associated nuclear antigen that is defined by monoclonal antibody Ki-67
    • Gerdes J, Li L, Schlueter C, et al. Immunobiochemical and molecular biologic characterization of the cell proliferation-associated nuclear antigen that is defined by monoclonal antibody Ki-67. Am J Pathol 1991;138:867-73.
    • (1991) Am J Pathol , vol.138 , pp. 867-873
    • Gerdes, J.1    Li, L.2    Schlueter, C.3
  • 15
    • 0021212003 scopus 로고
    • Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67
    • Gerdes J, Lemke H, Baisch H, Wacker HH, Schwab U, Stein H. Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. J Immunol 1984;133:1710-5.
    • (1984) J Immunol , vol.133 , pp. 1710-1715
    • Gerdes, J.1    Lemke, H.2    Baisch, H.3    Wacker, H.H.4    Schwab, U.5    Stein, H.6
  • 16
    • 0028922979 scopus 로고
    • Quantitative image analysis of MIB-1 immunoreactivity: A comparison with flow cytometric assessment of proliferative activity in invasive carcinoma of the breast
    • Ostrowski ML, Chakraborty S, Laucirica R, Brown RW, Greenberg SD. Quantitative image analysis of MIB-1 immunoreactivity: a comparison with flow cytometric assessment of proliferative activity in invasive carcinoma of the breast. Anal Quant Cytol Histol 1995;17:15-24.
    • (1995) Anal Quant Cytol Histol , vol.17 , pp. 15-24
    • Ostrowski, M.L.1    Chakraborty, S.2    Laucirica, R.3    Brown, R.W.4    Greenberg, S.D.5
  • 17
    • 0026438323 scopus 로고
    • DNA ploidy, proliferation, and neu-oncogene protein overexpression in breast carcinoma
    • Lee AK, Wiley B, Loda M, et al. DNA ploidy, proliferation, and neu-oncogene protein overexpression in breast carcinoma. Mod Pathol 1992;5:61-7.
    • (1992) Mod Pathol , vol.5 , pp. 61-67
    • Lee, A.K.1    Wiley, B.2    Loda, M.3
  • 18
    • 0029039796 scopus 로고
    • Proliferation markers in breast carcinoma: Mitotic figure count, S-phase fraction, proliferating cell nuclear antigen. Ki-67 and MIB-1
    • Keshgegian AA, Cnaan A. Proliferation markers in breast carcinoma: mitotic figure count, S-phase fraction, proliferating cell nuclear antigen. Ki-67 and MIB-1. Am J Clin Pathol 1995;104:42-9.
    • (1995) Am J Clin Pathol , vol.104 , pp. 42-49
    • Keshgegian, A.A.1    Cnaan, A.2
  • 19
    • 0026712173 scopus 로고
    • Comparison of cell proliferation in breast carcinoma using image analysis (Ki-67) and flow cytometfic systems
    • Kennedy JC, el-Badawy N, DeRose PB, Cohen C. Comparison of cell proliferation in breast carcinoma using image analysis (Ki-67) and flow cytometfic systems. Anal Quant Cytol Histol 1992;14:304-11.
    • (1992) Anal Quant Cytol Histol , vol.14 , pp. 304-311
    • Kennedy, J.C.1    El-Badawy, N.2    DeRose, P.B.3    Cohen, C.4
  • 20
    • 0025173549 scopus 로고
    • Immunoelectron-microscopic localization of a proliferation-associated antigen Ki-67 in MCF-7 cells
    • Isola J, Helin H, Kallioniemi OP. Immunoelectron-microscopic localization of a proliferation-associated antigen Ki-67 in MCF-7 cells. Histochem J 1990;22:498-506.
    • (1990) Histochem J , vol.22 , pp. 498-506
    • Isola, J.1    Helin, H.2    Kallioniemi, O.P.3
  • 21
    • 0025291292 scopus 로고
    • Comparative assessment of proliferation and DNA content in breast carcinoma by image analysis and flow cytometry
    • Dawson AE, Norton JA, Weinberg DS. Comparative assessment of proliferation and DNA content in breast carcinoma by image analysis and flow cytometry. Am J Pathol 1990; 136:1115-24.
    • (1990) Am J Pathol , vol.136 , pp. 1115-1124
    • Dawson, A.E.1    Norton, J.A.2    Weinberg, D.S.3
  • 22
    • 0028359509 scopus 로고
    • Correlation of Ki-67 antigen expression with mitotic figure index and tumor grade in breast carcinomas using the novel "paraffin"-reactive MIB 1 antibody
    • Weidner N, Moore DH, Vartanian R. Correlation of Ki-67 antigen expression with mitotic figure index and tumor grade in breast carcinomas using the novel "paraffin"-reactive MIB 1 antibody. Hum Pathol 1994;25:337-42.
    • (1994) Hum Pathol , vol.25 , pp. 337-342
    • Weidner, N.1    Moore, D.H.2    Vartanian, R.3
  • 23
    • 0027057589 scopus 로고
    • Monoclonal antibodies against recombinant parts of the Ki-67 antigen (MIB 1 and MIB 3) detect proliferating cells in microwave-processed formalin-fixed paraffin sections
    • Cattoretti G, Becker MH, Key G, et al. Monoclonal antibodies against recombinant parts of the Ki-67 antigen (MIB 1 and MIB 3) detect proliferating cells in microwave-processed formalin-fixed paraffin sections. J Pathol 1992; 168:357-63.
    • (1992) J Pathol , vol.168 , pp. 357-363
    • Cattoretti, G.1    Becker, M.H.2    Key, G.3
  • 24
    • 0027265154 scopus 로고
    • New Ki-67-equivalent murine monoclonal antibodies (MIB 1-3) generated against bacterially expressed parts of the Ki-67 cDNA containing three 62 base pair repetitive elements encoding for the Ki-67 epitope
    • Key G, Becker MH, Baron B, et al. New Ki-67-equivalent murine monoclonal antibodies (MIB 1-3) generated against bacterially expressed parts of the Ki-67 cDNA containing three 62 base pair repetitive elements encoding for the Ki-67 epitope. Lab Invest 1993;68:629-36.
    • (1993) Lab Invest , vol.68 , pp. 629-636
    • Key, G.1    Becker, M.H.2    Baron, B.3
  • 25
    • 0027173695 scopus 로고
    • Detection of the Ki-67 antigen in fixed and wax-embedded sections with the monoclonal antibody MIB 1
    • McCormick D, Chong H, Hobbs C, Datta C, Hall PA. Detection of the Ki-67 antigen in fixed and wax-embedded sections with the monoclonal antibody MIB 1. Histopathology 1993;22:355-60.
    • (1993) Histopathology , vol.22 , pp. 355-360
    • McCormick, D.1    Chong, H.2    Hobbs, C.3    Datta, C.4    Hall, P.A.5
  • 26
    • 0001301691 scopus 로고
    • Microwave-based antigenic unmasking: A revolutionary new technique for routine immunohistochemistry
    • Gown AM, de Wever N, Battifora H. Microwave-based antigenic unmasking: a revolutionary new technique for routine immunohistochemistry. Appl Immunohistochem 1993; 1:256-66.
    • (1993) Appl Immunohistochem , vol.1 , pp. 256-266
    • Gown, A.M.1    De Wever, N.2    Battifora, H.3
  • 27
    • 0019423594 scopus 로고
    • Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: A comparison between ABC and unlabeled antibody (PAP) procedures
    • Hsu SM, Raine L, Fanger H. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. J Histochem Cytochem 1981;29:577-80.
    • (1981) J Histochem Cytochem , vol.29 , pp. 577-580
    • Hsu, S.M.1    Raine, L.2    Fanger, H.3
  • 28
    • 0021332859 scopus 로고
    • Monoclonal antibodies to human intermediate filament proteins. II. Distribution of filament proteins in normal human tissues
    • Gown AM, Vogel AM. Monoclonal antibodies to human intermediate filament proteins. II. Distribution of filament proteins in normal human tissues. Am J Pathol 1984;114:309-21.
    • (1984) Am J Pathol , vol.114 , pp. 309-321
    • Gown, A.M.1    Vogel, A.M.2
  • 29
    • 0021083089 scopus 로고
    • Method for analysis of cellular DNA content of paraffin-embedded pathological material using flow cytometry
    • Hedley DW, Friedlander ML, Taylor IW, Rugg CA, Musgrove EA. Method for analysis of cellular DNA content of paraffin-embedded pathological material using flow cytometry. J Histochem Cytochem 1983;31:1333-5.
    • (1983) J Histochem Cytochem , vol.31 , pp. 1333-1335
    • Hedley, D.W.1    Friedlander, M.L.2    Taylor, I.W.3    Rugg, C.A.4    Musgrove, E.A.5
  • 30
    • 0024543886 scopus 로고
    • Flow cytometry using paraffin-embedded tissue: Five years on
    • Hedley DW. Flow cytometry using paraffin-embedded tissue: five years on. Cytometry 1989;10:229-41.
    • (1989) Cytometry , vol.10 , pp. 229-241
    • Hedley, D.W.1
  • 31
    • 70449185514 scopus 로고
    • Histological grading and prognosis in breast cancer: A study of 1,409 cases of which 359 have been followed for 15 years
    • Bloom HJG, Richardson WW. Histological grading and prognosis in breast cancer: a study of 1,409 cases of which 359 have been followed for 15 years. Br J Cancer 1957;9: 359-77.
    • (1957) Br J Cancer , vol.9 , pp. 359-377
    • Bloom, H.J.G.1    Richardson, W.W.2
  • 32
    • 0026072872 scopus 로고
    • Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: Experience from a large study with long-term follow-up
    • Elston CW, Ellis IO. Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up. Histopathology 1991;19:403-10.
    • (1991) Histopathology , vol.19 , pp. 403-410
    • Elston, C.W.1    Ellis, I.O.2
  • 33
    • 0023683287 scopus 로고
    • The evaluation of estrogen receptor in primary breast carcinoma by computer-assisted image analysis
    • Bacus S, Flowers JL, Press MF, Bacus JW, McCarty KS Jr. The evaluation of estrogen receptor in primary breast carcinoma by computer-assisted image analysis [Comments]. Am J Clin Pathol 1988;90:233-9.
    • (1988) Am J Clin Pathol , vol.90 , pp. 233-239
    • Bacus, S.1    Flowers, J.L.2    Press, M.F.3    Bacus, J.W.4    McCarty Jr., K.S.5
  • 34
    • 0025670027 scopus 로고
    • Ki67 index and S-phase fraction in human breast carcinomas: Comparison and correlations with prognostic factors
    • Vielh P, Chevillard S, Mosseri V, Donatini B, Magdelenat H. Ki67 index and S-phase fraction in human breast carcinomas: comparison and correlations with prognostic factors. Am J Clin Pathol 1990;94:681-6.
    • (1990) Am J Clin Pathol , vol.94 , pp. 681-686
    • Vielh, P.1    Chevillard, S.2    Mosseri, V.3    Donatini, B.4    Magdelenat, H.5
  • 35
    • 0024800348 scopus 로고
    • Two-color multiparametric method for flow cytometric DNA analysis of carcinomas using staining for cytokeratin and leukocyte-common antigen
    • Zarbo RJ, Visscher DW, Crissman JD. Two-color multiparametric method for flow cytometric DNA analysis of carcinomas using staining for cytokeratin and leukocyte-common antigen. Anal Quant Cytol Histol 1989;11:391-402.
    • (1989) Anal Quant Cytol Histol , vol.11 , pp. 391-402
    • Zarbo, R.J.1    Visscher, D.W.2    Crissman, J.D.3
  • 36
    • 0024581202 scopus 로고
    • Cell proliferation in non-Hodgkin's lymphomas: Digital image analysis of Ki-67 antibody staining
    • Schwartz BR, Pinkus G, Bacus S, Toder M, Weinberg DS. Cell proliferation in non-Hodgkin's lymphomas: digital image analysis of Ki-67 antibody staining. Am J Pathol 1989; 134:327-36.
    • (1989) Am J Pathol , vol.134 , pp. 327-336
    • Schwartz, B.R.1    Pinkus, G.2    Bacus, S.3    Toder, M.4    Weinberg, D.S.5
  • 37
    • 0028797073 scopus 로고
    • Assessment of the new proliferation marker MIB 1 in breast carcinoma using image analysis: Associations with other prognostic factors and survival
    • Pinder SE, Wencyk P, Sibbering DM, et al. Assessment of the new proliferation marker MIB 1 in breast carcinoma using image analysis: associations with other prognostic factors and survival. Br J Cancer 1995;71:146-9.
    • (1995) Br J Cancer , vol.71 , pp. 146-149
    • Pinder, S.E.1    Wencyk, P.2    Sibbering, D.M.3
  • 40
    • 0027223326 scopus 로고
    • Quantitation of smooth muscle proliferation in cultured aorta: A color image analysis method for the Macintosh
    • Kuyatt BL, Reidy CA, Hui KY, Jordan WH. Quantitation of smooth muscle proliferation in cultured aorta: a color image analysis method for the Macintosh. Anal Quant Cytol Histol 1993;15:83-7.
    • (1993) Anal Quant Cytol Histol , vol.15 , pp. 83-87
    • Kuyatt, B.L.1    Reidy, C.A.2    Hui, K.Y.3    Jordan, W.H.4
  • 41
    • 0029351849 scopus 로고
    • Ki-67 reactivity in breast carcinoma analyzed by a computer-assisted image system: Preliminary results
    • Mir R, Johnson H Jr., Mathur R, Wise L, Kahn LB. Ki-67 reactivity in breast carcinoma analyzed by a computer-assisted image system: preliminary results. J Natl Med Assoc 1995;87:554-9.
    • (1995) J Natl Med Assoc , vol.87 , pp. 554-559
    • Mir, R.1    Johnson Jr., H.2    Mathur, R.3    Wise, L.4    Kahn, L.B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.