Pharmacological characterization of novel tissue kallikrein inhibitors in vivo

Immunopharmacology

Volumn 32, Issue 1-3, 1996, Pages 111-114

  Bizeto, Luciana ^a   Antunes, Edson ^a   Portaro, Fernanda C V ^b   Juliano, Maria Aparecida ^b   Juliano, Luiz ^b   Prado, Eline S ^b   De Nucci, Gilberto ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Rabbit skin; Tissue kallikrein; Vascular permeability

Indexed keywords

ENZYME INHIBITOR; KALLIKREIN; KALLIKREIN INHIBITOR; SYNTHETIC PEPTIDE;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; BLOOD VESSEL PERMEABILITY; CONFERENCE PAPER; CONTROLLED STUDY; EDEMA; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT; SWINE;

EID: 0029888582     PISSN: 01623109     EISSN: None     Source Type: Journal    
DOI: 10.1016/0162-3109(95)00067-4     Document Type: Conference Paper

References (9)

1. Bhoola, K.D., Figueroa, C.D., Worthy, K. Bioregulation of kinins: kallikreins, kininogens and kininases. Pharmacol. Rev. 1992; 44: 4-80.
2. Bonner, G., Preis, S., Schunk, U., Iwersen, D. Hemodynamic effects of kinins and their role in blood pressure regulation. In: Fritz, H., Schmidt, I., Dietze, G., Eds. The Kallikrein-kinin system in health and disease. Germany: Limbach-Verlag Braunschweig, 1988; 79-96.
3. Chagas, J.R., Juliano, L., Prado, E.S. Intramolecularly quenched fluorogenic tetrapeptide substates for tixxue and plasma kallikreins. Anal. Biochem. 1991; 192:419.
4. Lopes-Martins, R.A.B., Antunes, E., Oliva, M.L., Samapio, C., Burton, J., de Nucci, G. Pharmacological characterization of rabbit corpus cavernosum relaxation mediated by tissue kallikrein-kinin system. Br. J. Pharmacol. 1994; 113: 81-86.
5. Marangoni, R.A., Antunes, E., Brain, S.D., de Nucci, G. Activation by Phoneutria nigriventer (armed spider) venom of tissue-kallikrein-kinin system in rabbit skin in vivo. Br. J. Pharmacol. 1993; 109: 539-543.
6. Margolius, H.S. Tissue kallikreins and kinins: Regulation and roles in hypertensive and diabetic diseases. Ann. Rev. Pharmacol. Toxicol. 1989; 29: 343-364.
7. Schill, W.-B., Miska, W., Parsch, E.-M., Fink, E. Significance of the kallikrein-kinin system in andrology. In: Fritz, H., Schmidt, I., Dietze, G., Eds. The Kallikrein-kinin system in health and disease. Germany: Limbach-Verlag Braunschweig, 1988; 171-203.
8. Vogel, R. Kalllikrein inhibitors. In: Bradykinin, kallidin and kallikrein. Handb. Exp. Pharmacol. Berlin, Heidelberg: Springer-Verlag., 1979 (Vol. XXV); 163-225.
9. 2 and the vascular changes in inflammation. Br. J. Pharmacol. 1979; 65: 517-524.