Endogenous antioxidant status in neoplastic and adjacent tissues in 1,2-dimethylhydrazine-induced colon cancer in rats: Effects of olsalazine

Carcinogenesis

Volumn 17, Issue 5, 1996, Pages 983-987

  Moghadasian, Mohammed H ^a   Freeman, Hugh J ^a   Godin, David V ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 DIMETHYLHYDRAZINE; ANTIOXIDANT; CARCINOGEN; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; MESALAZINE; OLSALAZINE; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; COLON CANCER; COLON CARCINOGENESIS; CONTROLLED STUDY; ENZYME ACTIVITY; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT;

1,2-DIMETHYLHYDRAZINE; AMINOSALICYLIC ACIDS; ANIMALS; ANTIOXIDANTS; COLONIC NEOPLASMS; DIMETHYLHYDRAZINES; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; MALE; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE;

EID: 0029888548     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/17.5.983     Document Type: Article

References (44)

1. Babbs,C.F. (1990) Free radicals and the etiology of colon cancer. Free Radical Biol. Med., 8, 191-200.
2. Phull,P.S., Green,C.G. and Jacyna,M.R. (1995) A radical view of the stomach: the role of the oxygen-derived free radicals and antioxidants in gastrointestinal disease. Eur. J. Gastroenterol. Hepatol., 7, 265-274.
3. Jourd'heuil,D., Mehta,S. and Meddings,J.B. (1995) Hemileaflet susceptibility to oxidative damage in intestinal brush-border membrane. Am. J. Physiol., 268, G260-G269.
4. Salim,A.S. (1991) Gastric mucosal cytoprotection in the rat by scavenging oxygen-derived free radicals. Am. J. Med. Sci., 302, 287-291.
5. Singh,A. (1982) Chemical and biochemical aspects of superoxide radicals and related species of activated oxygen. Can. J. Physiol. Pharmacol., 60,1330-1345.
6. Halliwell,B. and Gutteridge,J.M.C. (1986) Oxygen free radicals and iron in relation to biology and medicine: some problems and concepts. Arch. Biochem. Biophys., 246, 501-514.
7. Halliwell,B. (1991) Drug antioxidant effects. A basis for drug selection? Drugs, 42, 569-605.
8. Imlay,J.A. and Linn,S. (1988) DNA damage and oxygen radical toxicity. Science, 240, 1302-1309.
9. Hassan,H.M. and Moody,C.S. (1984) Determination of the mutagenicity of oxygen free radicals using microbial systems. Methods Enzymol., 105, 254-263.
10. Ames,B.N. (1989) Endogenous oxidative DNA damage, aging and cancer. Free Radical Commun., 7, 121-128.
11. Malins,D.C. and Haimanot,R. (1991) Major alterations in the nucleotide structure of DNA in cancer of the female breast. Cancer Res., 51, 5430-5432.
12. Floyd,R.A., Watson,J.J., Harris.J., West,M. and Wong,P.K. (1986) Formation of 8-hydroxydeoxyguanosine. hydroxyl free radical adduct of DNA in granulocytes exposed to the tumor promoter, tetradecanoylphorbol acetate. Biochem. Biophys. Res. Commun., 137, 841-846.
13. Shibutani,S., Takeshita,M. and Grollman,A.P. (1991) Insertion of specific bases during DNA synthesis past the oxidation damaged base 8-oxoG. Nature, 349, 431-434.
14. Kvietys,P.R., Smith,S.M., Grisham,M.B. and Manci,E.A. (1988) 5-Aminosalicylic acid protects against ischemia/reperfusion-induced gastric bleeding in rat. Gastroenterology, 94, 733-738.
15. Nielsen,O.H., Bouchelouche,P.N., Berild,D. and Ahnfelt-Ronne,I. (1993) Effects of 5-aminosalicylic acid and analogous substances on superoxide generation and intracellular free calcium in human neutrophilic granulocytes. Scand. J. Gastroenterol., 28, 527-532.
16. Allgayer,H., Hofer,R. Schmidt,M., Bohne,P., Kruis,W. and Gugler,R. (1992) Superoxide, hydroxyl and fatty acid radical scavenging by aminosalicylates. Biochem. Pharmacol., 43, 259-262.
17. Freeman,H.J. (1986) Effects of differing purified cellulose, pectin, and hemicellulose fiber diets on fecal enzymes in 1,2-dimethylhydrazine-induced rat colon carcinogenesis. Cancer Res., 46, 5529-5532.
18. Scudamore,C.H. and Freeman,H.J. (1983) Effects of small bowel transection, resection or bypass in 1.2-dimethylhydrazine-induced rat intestinal neoplasia. Gastroenterology, 84, 725-731.
19. Calderisi,R.N. and Freeman,H.J. (1984) Differential effects of surgical suture materials in 1,2-dimethylhydrazine-induced rat intestinal neoplasia. Cancer Res., 44, 2827-2830.
20. Freeman, H.J. (1990) Animal studies of colon carcinogenesis and altered epithelial cell differentiation. Can. J. Gastroenterol., 4, 372-377.
21. Long,W.K. and Carson,P.E. (1961) Increased erythrocyte glutathione reductase in diabetes mellitus. Biochem. Biophys. Res. Commun., 5. 394-399.
22. Paglia,D.E. and Valentine,N.W. (1967) Studies on the quantitative characterization of erythrocyte glutathione peroxidase. J. Lab. Clin. Med., 70, 158-169.
23. Winterbourn,C.C., Hawkins,R.E., Brian,M. and Carrell,R.W. (1975) The estimation of red cell superoxide dismutase activity. J. Lab. Clin. Med., 85, 337-341.
24. Moghadasian,M.H. and Godin,D.V. (1996) Species-related variations in gastrointestinal antioxidant profiles. Comp. Biochem. Physiol., in press.
25. Aebi,H. (1974) Catalase. In Bergmeyer,H.V. (ed.), Methods of Enzymatic Analysis. Chemie, Weinheim, Germany, pp. 673-684.
26. Qureshi,A., Gorey,T.F, Byme,R, Kay,E., McKeever,J. and Hennessy,T.P. (1994) Oxygen free radical activity in experimental colonic carcinoma. Br. J. Surg., 81, 1058-1059.
27. Slaga,T.J. (1995) Inhibition of skin tumor initiation, promotion and progression by antioxidants and related compounds. Crit. Rev. Food Sci. Nutr., 35, 51-57.
28. Perchellet,J.P., Owen,M.D., Posey,T.D., Orten,D.K. and Schneider,B.A. (1985) Inhibitory effects of glutathione level-raising agents and D-α-tocopherol on ornithine decarboxylase induction and mouse skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate. Carcinogenesis, 6, 567-573.
29. Kinsella,A.R., St C.-Gainer,H. and Butler,J. (1983) Investigation of a possible role for superoxide anion production in tumor promotion. Carcinogenesis, 4, 717-719.
30. Solanki, V., Rana,R.S. and Slaga,T.J. (1981) Diminution of mouse epidermal superoxide dismutase and catalase activities by tumor promoters. Carcinogenesis, 2, 1141-1146.
31. Bostick,R.M., Potter,J.D., McKenzie,D.R., Sellers,T.A., Kushi,L.H., Steinmetz,K.A. and Folsom,A.R. (1993) Reduced risk of colon cancer with high intake of vitamin E: the Iowa Women's Health Study. Cancer Res., 53, 4230-4237.
32. Roncucci,L. et al. (1993) Antioxidant vitamins or lactulose for the prevention of recurrence of colorectal adenomas. Dis. Colon Rectum, 36, 227-234.
33. Cahill,J., O'Sullivan,K.R., Mathias,P.M, Beattie,S., Hamilton,H., O'Morian,C. (1993) Effects of vitamin antioxidant supplementation on cell kinetics of patients with adenomatous polyps. Gut. 34, 963-967.
34. Alabaster,O., Tang,Z., Frost,A. and Shivapurkar,N. (1995) Effects of β-carotene and wheat bran fiber on colonic aberrant crypt and tumor formation in rats exposed to azoxymethane and high dietary fat. Carcinogenesis, 16, 127-132.
35. Stahelin,H.B., Rosel,F., Buess,E. and Brubacher,G. (1984) Cancer, vitamins and plasma lipids: prospective Basel study. J. Natl Cancer Inst., 73, 1463-1468.
36. DiSilvestro,A., Greenson,J.K. and Liao,Z., (1992) Effects of low copper intake on dimethylhydrazine-induced colon cancer in rats. Proc. Soc. Exp. Biol. Med., 201, 94-97.
37. Greene,L., Lamb,L.S., Barwick,M. and Pappas,N.J. (1987) Effect of dietary copper on colonic tumor production and aortic integrity in the rat. J. Surg. Res., 42, 503-512.
38. Broghamer,W.L., McConnell,J.R., Blotcky,K.P. (1976) Relationship between serum selenium levels and patients with carcinoma. Cancer, 37, 1384-1388.
39. Verspaget,H.W., Mulder,T.P.J., Vander Sluys Veer,A., Pena,A.S. and Lamers,C.B.H.W. (1991) Reactive oxygen metabolites and colitis: a disturbed balance between damage and protection. Scand. J. Gastroenterol., 26 (Suppl. 188), 44-51.
40. Salim,A.S. (1992) Role of oxygen-derived free radical scavengers in the managment of recurrent attacks of ulcerative colitis: a new approach. J. Lab. Clin. Med., 119, 710-717.
41. Christman,M.F., Storz,G. and Ames,B.N. (1989) OxyR. a positive regulator of hydrogen peroxide-inducible genes in Escherichia coli and Salmonella typhimurium, is homologous to a family of bacterial regulatory proteins. Proc. Natl Acad. Sci. USA, 86, 3484-3488.
42. Nicotera,T.M., Block,A.W., Gibas,Z. and Sandberg,A.A. (1985) Induction of superoxide dismutase, chromosomal aberrations and sister chromatid exchanges by paraquat in Chinese hamster fibroblasts. Mutat. Res., 151, 263-268.
43. Applegate,L.A., Luscher,P. and Tyrrell,R.M. (1991) Induction of heme oxygenase: a general response to oxidant stress in cultured mammalian cells. Cancer Res., 51, 974-978.
44. Hoffman,E.J., Webster,N.R., Wiggins,P.A., Chisholm,E.M., Glies,G.R. and Leveson,S.H. (1985) Free radical detoxifying systems in human colorectal cancer. Br. J. Cancer, 51, 127-129.