Infrequent alterations of the p53 gene in rat skin cancers induced by ionizing radiation

Carcinogenesis

Volumn 17, Issue 4, 1996, Pages 873-876

  Jin, Yi ^a   Burns, Fredric J ^b   Garte, Seymour J ^b   Hosselet, Steve ^b  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b NEW YORK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NEON; PROTEIN P53;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA STRAND BREAKAGE; ELECTRON RADIATION; EXON; GENE DELETION; GENE MUTATION; GENE REARRANGEMENT; IONIZING RADIATION; MALE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RADIATION CARCINOGENESIS; RADIATION ENERGY; RAT; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SKIN CARCINOGENESIS; SOUTHERN BLOTTING; TUMOR SUPPRESSOR GENE;

ANIMALS; BASE SEQUENCE; DNA PRIMERS; GENES, P53; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; NEOPLASMS, RADIATION-INDUCED; RADIATION, IONIZING; RATS; SKIN NEOPLASMS;

EID: 0029888038     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/17.4.873     Document Type: Article

References (33)

1. Land,H., Parada,L.F. and Weinberg,R.A. (1983) Cellular oncogenes and multistep carcinogenesis. Science, 222, 771-778.
2. Nowell,P.C. (1976) The clonal evolution of tumour cell populations. Science, 194, 23-28.
3. Barns,F.J., Albert,R.E and Garte,S.J. (1989) Multiple stages in radiation carcinogenesis of rat skin. Environ. Health Perspect., 81, 67-72.
4. Roop,D.R., Krieg,T.M., Mehrel,T. et al. (1988) Transcnptional control of high molecular weight keratin gene expression in multistage mouse skin carcinogenesis. Cancer Res., 48, 3245-3252.
5. Garte,S.I., Burns,F.J., Ashkenazi-Kimmel,T., Cosma,G.N. and Sawey,M.J. (1989) An experimental model for oncogene activation during tumour progression in vivo Anticancer Res., 9, 1439-1446.
6. Garte,S.J. and Burns,F.J. (1991) Oncogenes and radiation carcinogenesis. Environ. Health Perspect., 93, 45-49.
7. Sawey,M.J., Hood,A.T., Burns,F.J. and Garte,S.J. (1987) Activation of K-ras and c-myc oncogenes in radiation-induced rat skin tumours. Mol. Cell. Biol., 7, 932-957
8. Garte,S.J., Burns,F.J., Ashkenazi-Kimmel,T., Felber,M. and Sawey,M.J. (1990) Amplification of the c-myc oncogene during progression of radiation-induced rat skin tumours. Cancer Res., 50, 3073-3077.
9. Jin,Y., Burns,F.J. and Garte,S.J. (1992) Oncogene amplification detected by in situ hybridization in radiation-induced rat skin tumours. Radiat. Res., 132, 193-199.
10. Felber,M., Burns,F.J. and Garte,S.J. (1992) Amplification of the c-myc oncogene in radiation-induced rat skin tumours as a function of LET and dose. Radiat. Res., 131, 297-301.
11. Weinberg,R.A. (1991) Tumor suppressor genes. Science, 254, 1138-1177.
12. Marshall,C.J. (1991) Tumor suppressor genes. Cell, 64, 313-326.
13. Lee,E.Y.H.P., To,H., Shew,J.Y., Bookstein,R., Scully,P. and Lee,W.H. (1988) Inactivation of the retinoblastoma susceptibility gene in human breast cancers. Science, 241, 218-221
14. Harbour,J.W., Lai,S.L., Whang-Peng,J., Gazdar,A.F., Minna,J.D. and Kaye,F.J. (1988) Abnormalities in structure and expression of the human retinoblastoma gene in SCLC. Science. 241, 353-356.
15. Hensel,C.H , Hseih.C.L., Gazdar,A.F. Johnson,B.E. et al. (1990) Altered structure and expression of the human retinoblastoma susceptibility gene in small cell lung cancer. Cancer Res., 50, 3067-3072.
16. Bookstein,R., Rio,P., Madreperla,S.A., Hong,R. Allred,C., Grizzle,W.E. and Lee,W.H. (1990) Promoter deletion and loss of retinoblastoma gene expression in human prostate carcinoma. Proc. Natl Acad. Sci USA. 87, 7762-7766.
17. Hollstein,M., Sidransky,D., Vogelstein,B. and Harris,C.C. (1991) p53 mutations in human cancers. Science. 253, 49-53.
18. Okamoto,A., Sameshima,Y., Yokoyama,S., Terashima,Y., Sugimura,T., Terada,M. and Yokota,J. (1991) Frequent allelic losses and mutations of the p53 gene in human ovarian cancer. Cancer Res. 51, 5171-5176.
19. Kastan,M.B., Zhan,Q , El-Deiry,W.S., Carrier,F., Jacks,T., Walsh,W.V., Plunkett,B.S., Vogelstein,B. and Fornac,A.J., Jr (1992) A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia telangiectasia. Cell. 71, 587-597.
20. Sambrook,J., Fritsch,E.F. and Maniatis,T. (1988) Isolation of high-molecular-weight DNA from mammalian cells. In Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, pp. 14-19.
21. Innis,M.A., Myambo,K.B., Gelfand,D.H. and Brow,M.A.D. (1988) DNA sequencing with Thermus aquaticus DNA polymerase and direct sequencing of polymerase chain reaction-amplified DNA. Proc. Natl Acad. Sci. USA. 85, 9436-9440.
22. Murray,V. (1989) Improved double-stranded DNA sequencing using the linear polymerase chain reaction. Nucleic Acids Res., 17, 8889.
23. Lilleberg,S.L., Cabonce,M.A., Raju,C.N.R., Wagner,L.M. and Kier,L.D. (1992) Alterations in the structural gene and the expression of p53 in rat liver tumours induced by aflatoxin B1. Mol. Carcinogenesis, 6, 159-172.
24. Hulla,J.E. (1992) The rat genome contains a p53 pseudogene: detection of a processed pseudogene using PCR. PCR Methods Applic., 1, 251-254.
25. Hula,J.E. and Schneidor,R. (1993) Structure of the rat p53 tumour suppressor gene. Nucleic Acids Res., 21, 713-717.
26. Sousii,T., Fromentel.C.C., Breugnot,C. and May,E. (1988) Nucleotide sequence of a cDNA encoding the rat p53 nuclear oncoprotein. Nucleic Acids Res., 16, 11384.
27. Takahashi,T., D'Amico,D., Chiba,I., Buchhagen,D.L. and Minna,J.D. (1990) Identification of intronic point mutations as an alternative mechanism for p53 inactivation in lung cancer. J. Clin. Invest., 86, 363-369.
28. Lozano,G. and Levine,A.J. (1991) Tissue-specific expression of p53 in transgenic mice is regulated by intron sequences. Mol. Carcinogenesis. 4, 3-9.
29. Vahakangas,K.H., Samet,J.M., Metcalf,R.A., Welsh,J.A., Bennett,W.P., Lane,D.P. and Harris,C.C. (1992) Mutations of p53 and ras genes in radon-associated lung cancer from uranium miners. Lancet, 339, 576-580.
30. Thraves,P.J., Varghese,S., Jung,M., Grdina,D.J., Rhim,J.S. and Dritschilo,A. (1994) Transformation of human epidermal keratinocytes with fission neutrons. Carcinogenesis, 15, 2867-2873.
31. Stubblefield,E. (1991) The genetic changes in cancer. Mol. Carcinogenesis. 4, 257-260.
32. Kronenberg,A. and Little,J.B. (1989) Molecular characterization of thymidine kinase mutants of human cells induced by densely ionizing radiation. Mutat. Res., 211, 215-224.
33. Sloan,S.R., Newcomb,E.W. and Pellicer,A. (1990) Neutron radiation can activate K-ras via a point mutation in codon 146 and induces a different spectrum of ras mutations than does gamma radiation. Mol. Cell. Biol., 10. 405-408.