Lewy body diseases: Possible new directions in prophylaxis and therapy

Medical Hypotheses

Volumn 46, Issue 3, 1996, Pages 222-224

  Oken, R J ^a  

^a NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; INDOMETACIN; NONSTEROID ANTIINFLAMMATORY AGENT; STEROID;

ALZHEIMER DISEASE; DEMENTIA; HUMAN; LEWY BODY; NEUROPATHOLOGY; PARKINSON DISEASE; PRIORITY JOURNAL; SHORT SURVEY;

EID: 0029887977     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-9877(96)90244-3     Document Type: Article

References (10)

1. Trojanowski J Q, Lee V M. Phosphorylation of neuronal cytoskeletal proteins in Alzheimer's disease and Lewy body dementias. In: Disterbo JF, Gispen W H, Traber J, Khachaturian Z S, eds. Calcium Hypothesis of Aging and Dementia. Ann NY Acad Sci 1994; 747: 92-109.
2. Perry E K, Mckeith I, Thompson P et al. Topography, extent, and clinical relevance of neurochemical deficits in dementia of Lewy body type, Parkinson's disease, and Alzheimer's disease. In: Growdon J H, Corkin S, Ritter-Walker E, Wurtman R J, eds. Aging and Alzheimer's Disease. Ann NY Acad Sci 1991; 640: 197-202.
3. Förstl H, Burns A, Luthert P et al. The Lewy body variant of Alzheimer's disease, clinical and pathological finds. Br Psychiatry 1993; 162: 385-392.
4. McKeith I G, Fairbairn A F, Bothwell R A et al. An evaluation of the predictive validity and inter-rater reliability of clinical diagnostic criteria for senile dementia of Lewy body type. Neurology 1994; 44: 872-877.
5. McGeer P L, Itagaki S, Tago H et al. Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR. Neurosci Lett 1987; 79: 195-200.
6. McGeer P L, Itagaki S, Boyes B E et al. Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains. Neurology 1988; 38: 1285-1291.
7. McGeer P L, Rogers J. Anti-inflammatory agents as a therapeutic approach to Alzheimer's disease. Neurology 1992; 42: 447-449.
8. Klegeris A, McGeer P L. Rat brain microglia and peripheral macrophages show similar responses to respiratory burst stimulants. Neuroimmunology 1994; 53: 83-90.
9. Rogers J, Kirby L C, Hempelman S R et al. Clinical trial of indomethacin in Alzheimer's disease. Neurology 1993; 43: 1609-1616.
10. Breitner J C, Gau B A, Weish K A et al. Inverse association of antiinflammatory treatments and Alzheimer's disease: initial results of a co-twin study. Neurology 1994; 44: 227-232.