Elevated circulating levels of TNFα and its p55 soluble receptor are associated with an adverse prognosis in lymphoma patients

British Journal of Haematology

Volumn 93, Issue 2, 1996, Pages 352-359

  Salles, Gilles ^a,b   Bienvene, Jacques ^a   Bastion, Yves ^a   Barbier, Yves ^a   Doche, Christophe ^a   Warzocha, Krzysztof ^a   Gutowski, Marie Clude ^a   Rieux, Claire ^a   Coiffier, Bertrand ^a  

^a HOSPICES CIVILS DE LYON   (France)

^b CENTRE HOSPITALIER LYON SUD   (France)

Author keywords

cytokines; lymphoma; prognostics; TNF; TNF receptor

Indexed keywords

ANTINEOPLASTIC AGENT; CHLORAMBUCIL; FLUDARABINE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR;

ADOLESCENT; ADULT; AGED; ARTICLE; BLOOD LEVEL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NONHODGKIN LYMPHOMA; PRIORITY JOURNAL; PROGNOSIS;

EID: 0029887909     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1996.5181059.x     Document Type: Article

References (41)

1. Aaronson, S.A. (1991) Growth factors and cancer. Science, 254, 1146-1153.
2. Adami, F., Guarini, A., Pini, M., Siviero, F., Sancetta, R., Massiai, M., Trentin, L., Foa, R. & Semenzato, G. (1994) Serum levels of tumor necrosis factor-alpha in patients with B-cell chronic lymphocytic leukaemia. European Journal of Cancer, 30A, 1259-1263.
3. Aderka, D., Engelmann, H., Hornik, V., Skornick, Y., Levo, Y., Wallach, D. & Kushtar, G. (1991) Increased serum levels of soluble receptors for tumour necrosis factor in cancer patients. Cancer Research, 51, 5602-5609.
4. Aderka, D., Engelmann, H., Maor, Y., Brakebush, C. & Wallach, D. (1992) Stabilization of the bioactivity of tumojr necrosis factor by its soluble receptors. Journal of Experimental Medicine, 175, 323-329.
5. Balkwill, F., Burke, F., Talbot, D., Tavernier, J., Osborne, R., Naylor, S., Durbin, H. & Fiers, W. (1987) Evidence for tumour necrosis factor/cachectin production in cancer patients. Lancet, ii, 1229-1232.
6. Banchereau, J., Bazan, F., Blanchard, D., Brière, F., Galizzi, J.P., van Kooten, C., Liu, Y.J., Rousset, F. & Saeland, S. (1994) The CD40 antigen and its ligand. Annual Review of Immunology, 12, 881-922.
7. Bemelmans, M.H.A., Gouma, D.J. & Burman, W.A. (1993) Influence of nephrectomy on tumor necrosis factor clearance in murine model. Journal of Immunology, 150, 2007-2017.
8. Beutler, B. (1992) Tumor Necrosis Factors: the Molecules and their Emerging Role in Medicine. Raven Press, New York.
9. Beutler, B. & van Huffel, C. (1994) Unraveling function in the TNF ligand and receptor families. Science, 264, 667-668.
10. Blay, J.Y., Burdin, N., Rousset, F., Lenoir, G., Biron, P., Philip, T., Banchereau, J. & Favrot, M.C. (1993) Serum interleukin-10 in non-Hodgkin's lymphoma: a prognostic factor. Blood, 82, 2169-2174.
11. Boussiotis, V.A., Nadler, L.M., Strominger, J.L. & Goldfeld, A.E. (1994) Tumor necrosis factor alpha is an autocrine growth factor for normal human B cells. Proceedings of the National Academy of Sciences of United States of America, 91, 7007-7011.
12. Broxmeyer, H.E., Williams, D.E., Lu, L., Cooper S., Anderson, S.L, Beyer, G.S., Hoffman, R. & Rubin, B. (1986) The suppressive influences of tumor necrosis factors on bone marrow hematopoietic progenitor cells from normal donors and patients with leukemia: synergism of TNF and IFN-gamma. Journal of Immunology, 136, 4487-4495.
13. Casey, L.C., Balk, R.A. & Bone, R.C. (1993) Plasma cytokine and endotoxin levels correlate with survival in patients with the sepsis syndrome. Annals of Internal Medicine, 119, 771-778.
14. Caux, C., Dezutter-Dambuyant, C., Schmitt, D. & Banchereau, J. (1992) GM-CSF and TNF-alpha cooperate in the generation of dendritic Langherans cells. Nature, 360, 258-261.
15. Coiffier, B., Gisselbrecht, C., Herbrecht, R., Tilly, H., Bosly, A. & Brousse, N. (1989) LNH-84: a multicenler study of intensive chemotherapy in 737 patients with aggressive malignant lymphoma. Journal of Clinical Oncology, 7, 1018-1026.
16. Cordingley, F.T., Hoffbrand, A.V., Heslop, H.E., Turner, M., Blanchi, A., Reittie, J.E., Vyakarnam, A. & Brenner, MK. (1988) Tumour necrosis factor as an autocrine growth factor for chronic B-cell malignancies. Lancet, i, 969-971.
17. Cross, M. & Dexter, T.M. (1991) Growth factors in development, transformation and tumorigenesis. Cell, 64, 271-280.
18. De Groote, D., Grau, G.E., Dehart, I. & Franchimont, P. (1993) Stabilisation of functional tumor necrosis factor-alpha by its soluble TNF receptors. European Cytokine Network, 4, 359-362.
19. Digel, W., Stefanic, M., Schoniger, W., Buck, C., Raghavachar, A., Frickhofen, N., Heimpel, H. & Porzsolt, F. (1989) Tumor necrosis factor induces proliferation of neoplaslic B-cells from chronic lymphocytic leukemia. Blood, 73, 1242-1246.
20. Foa, R., Massaia, M., Cardona, S., Tos, A.G., Bianchi, A., Attisano, C., Guarini, A., Dicelle, P.F. & Fierro, M.T. (1990) Production of tumor necrosis factor-alpha by B-cell chronic lymphocytic leukemia cells: a possible regulatory role of TNF in the progression of the disease. Blood, 76, 393-400.
21. Foss, H.D., Anagnostopoulos, I., Herbst, H., Grebe, M., Ziemann, K., Hummel, M. & Stein, H. (1995) Patterns of cytokine gene expression in peripheral T-cell lymphoma of angioimmunoblastic lymphadenopathy type. Blood, 85, 2862-2869.
22. Gruss, H.J., Dolken, G., Brach, M.A., Mertelsmann, R. & Herrman, F. (1993) The significance of serum levels of soluble 60 kD receptors for tumor necrosis factor in patients with Hodgkin's disease. Leukemia, 7, 1339-1343.
23. Gruss, H.-J. & Dower, S.K. (1995) Tumor necrosis factor ligand receptor superfamilly: involvement in the pathology of malignant lymphomas. Blood, 85, 3378-3404.
24. Hermans, J., Krol, A.D.G., van Groningen, K., Kluin, Ph., Kluin-Nelemans, J.C., Kramer, M.H.H., Noordijk, E.M., Ong, F. & Wijermans, P.W. (1995) International Prognostic Index for aggressive non-Hodgkin's lymphoma is valid for all malignancy grades. Blood, 86, 1460-1463.
25. Higuchi, M. & Aggarwal, B.B. (1992) Inhibition of ligand binding and antiproliferative effects of tumor necrosis factor and lymphotoxin by soluble forms of recombinant p60 and p80 receptors. Biochemical and Biophysical Research Communications, 182, 638-643.
26. Hoffbrand, A.V., Panayiotidis, P., Reittie, J. & Ganeshaguru, K. (1993) Autocrine and paracrine loops in chronic lymphocytic leukemia. Seminars in Hematology, 30, 306-317.
27. Jhaver, K., De, A., Advani, S. & Nadkarni, J. (1991) Production of interleukin-1 and tumor necrosis factor in non-Hodgkin's lymphoma patients. Cancer Immunology and Immunotherapy, 34, 123-127.
28. Klein, B., Zhang, X.-G., Lu, Z.-Y. & Bataille, R. (1995) Interleukin-6 in human multiple myeloma. Blood, 85, 863-872.
29. Lennert, K. & Feller, A.C. (1992) Histopathologie der Non-Hodgkin Lymphome (nach der acktualisierten Kiel-Klassifikation). Springer, Berlin.
30. López-Guillermo, A., Montserrat, E., Bosch, F., Terol, M.J., Campo, E. & Rozman, C. (1994) Applicability of the International Index for aggressive lymphomas to patients with low-grade lymphoma. Journal of Clinical Oncology, 12, 1343-1348.
31. Macia, J., Gomez, X., Perez, B., Esquerda, A., Parra, R. & Callao, V. (1994) Prognostic value of tumor necrosis factor in plasma of patients with chronic lymphoproliferative syndromes: preliminary results. Blood, 84, 989-991.
32. Roodman, G.D. (1992) TNF and hematopoiesis. Tumor Necrosis Factors: the Molecules and their Emerging Role in Medicine (ed. by B. Beutler), pp. 117-129. Raven Press, New York.
33. Ruggiero, V., Latham, K. & Baglioni, C. (1987) Cytostatic and cytotoxic activity of tumor necrosis factor on human cancer cells. Journal of Immunology, 138, 2711-2717.
34. Sappino, A.P., Seelentag, W., Pelte, M.F., Alberto, P. & Vassalli, P. (1990) Tumor necrosis factor cachectin and lymphotoxin gene expression in lymph nodes from lymphoma patients. Blood, 75, 958-962.
35. Schwartzentruber, D.J., Stetler-Stevenson, M., Rosenberg, S.A. & Topalian, S.L. (1993) Tumor-infiltrating lymphocytes derived from select B-cell lymphomas secrete granulocyte-macrophage colony-stimulating factor and tumor necrosis factor-α in response to autologous tumor stimulation. Blood, 82, 1204-1211.
36. Seymour, J.F., Talpaz, M., Cabanillas, F., Wetzler, M. & Kurzrock, R. (1995) Serum interleukin-6 levels correlate with prognosis in diffuse large cell lymphoma. Journal of Clinical Oncology, 13, 575-582.
37. Shipp, M.A., Harrington, D.P., Anderson, J.R., Armitage, J.O., Bonadonna, G., Brittinger, G., Cabanillas, F., Canellos, G.P., Coiffier, B., Connors, J.M., Cowan, R.A., Crowther, D., Dahlberg, S., Engelhard, M., Fisher, R.I., Gisselbrecht, C., Horning, S.J., Lepage, E., Lister, T.A., Meerwaldt, J.H., Montserrat, E., Nissen, N.I., Oken, M.M., Peterson, B.A., Tondini, C., Velasquez, W.A. & Yeap, B.Y. (1993) A predictive model for aggressive non-Hodgkin's lymphoma. New England Journal of Medicine, 329, 987-994.
38. Swan, F., Velasquez, W.S., Tucker, S., Redman, J. R., Rodriguez, M.A., McLaughlin, P., Hagemaister, F.B. & Cabanillas, F. (1989) A new serologic staging system for large-cell lymphomas based on initial β2-microglobulin and lactate dehydrogenase levels. Journal of Clinical Oncology, 7, 1518-1527.
39. Takeshita, M., Sumiyoshi, Y., Masuda, Y., Ohshima, K., Yoshida, T., Kikuchi, M. & Muller, H. (1993) Cytokine (Interleukin-1 alpha, interleukin-1beta, tumor necrosis factor-alpha, and interleukin-6)-possessing cells in lymph nodes of malignant lymphoma. Pathology Research and Practice, 189, 18-25.
40. Ulich, T.R., del Castillo, J. & Yin, S. (1989) TNF exerts dose-dependent effects on erythropoiesis in vivo. Experimental Hematology, 18, 311-315.
41. Van Zee, K.J., Kohno, T., Fisher, E., Rock, C.S., Moldawer, L.L. & Lowry, S.F. (1992) Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor alpha in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America, 89, 4845-4849.