Increasing heterogeneity of the 'a' determinant of HBsAg found in the presumed late phase of chronic hepatitis B virus infection

Scandinavian Journal of Infectious Diseases

Volumn 28, Issue 1, 1996, Pages 9-15

  Zhang, Yong Yuan ^a   Nordenfelt, Erik ^a   Hansson, Bengt Göran ^a,b  

^a LUND UNIVERSITY   (Sweden)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; ALANINE; GUANINE; HEPATITIS B ANTIBODY; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B VACCINE; THREONINE; VIRUS DNA;

ADULT; AGED; AMINO ACID SUBSTITUTION; ARTICLE; CHINA; CHRONIC HEPATITIS; DIAGNOSTIC ACCURACY; DISEASE COURSE; DNA SEQUENCE; DRUG EFFICACY; ENVELOPE GENE; FEMALE; GENE MUTATION; GENE SEQUENCE; GENETIC HETEROGENEITY; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; MAJOR CLINICAL STUDY; MALE; POINT MUTATION; POLYMERASE CHAIN REACTION; SERODIAGNOSIS; VIRUS ENVELOPE; VIRUS GENOME; VIRUS TRANSMISSION;

EID: 0029887820     PISSN: 00365548     EISSN: None     Source Type: Journal    
DOI: 10.3109/00365549609027142     Document Type: Article

References (32)

1. Le Bouvier GL. The heterogeneity of Australia antigen. J Infect Dis 123: 671-675, 1971.
2. Bancroft WH, Mundon FK, Russel PK. Detection of additional antigenic determinants of hepatitis B antigen. J Immunol 109: 842-848, 1972.
3. Okamoto H, Imai M, Tsuda F, Tanaka T, Miyakawa Y, Mayumi M. Point mutation in the S gene of hepatitis B virus for a d/y or w/r subtypic change in two blood donors carrying a surface antigen of compound subtype adyr or adwr. J Virol 61: 3030-3034, 1987.
4. McAuliffe VJ, Purcell RH, Gerin JL. Type B hepatitis: a review of current prospects for a safe and effective vaccine. Rev Infect Dis 2: 470-492, 1980.
5. Blum, HE, Liang TJ, Galun E, Wands JR. Persistence of hepatitis B viral DNA after serological recovery from hepatitis B virus infection. Hepatology 14: 56-62, 1991.
6. Carman W, Zanetti AR, Karayiannis P, Waters J, Manzillo G, Tanzi E, Zuckerman AJ, Thomas HC. Vaccine-induced escape mutant of hepatitis B virus. Lancet 336: 325-329, 1990.
7. Kremsdorf D, Thiers V, Garreau F, Nakajima E, Chappery C, Schellekens H, Wands JR, Sninsky J, Tiollais P, Brechot C. Nucleotide sequence analysis of hepatitis B virus genomes isolated from serologically negative patients. In: Hollinger FB, Lemon S.M. Margolis HS, eds. Viral hepatitis and liver disease. Baltimore: Williams & Wilkins, 222-226, 1991.
8. Lai MY, Chen PJ, Yang PM, Sheu JC, Sung JL, Chen DS. Identification and characterization of intrahepatic hepatitis B virus DNA in HBsAg-seronegative patients with chronic liver disease and hepatocellular carcinoma in Taiwan. Hepatology 12: 575-581, 1990.
9. Lee HS, Ulrich PP, Vyas GN. Mutations in the S-gene affecting the immunologie determinants of the envelope protein of hepatitis B virus. J Hepatol 13 (Suppl 4): 97-101, 1991.
10. Liang TJ, Blum HE, Wands JR. Characterization and biological properties of a hepatitis B virus isolated from a patient without hepatitis B virus serologic markers. Hepatology 12: 204-212, 1990.
11. Moriyama K, Nakajima E, Hohjoh H, Asayama R, Okochi K. Immunoselected hepatitis B virus mutant. Lancet 337: 125, 1991.
12. Brunetto MR, Giarin MM, Oliveri F, Chiaberge E, Baldi M, Alfarano A, Serra A, Saracco G, Verme G, Will H, Bonino F. Wild-type and e antigen-minus hepatitis B viruses and course of chronic hepatitis. Proc Natl Acad Sci USA 88: 4186-4190, 1991.
13. Carman WF, Jacyna MR, Hadziyannis S, Karayiannis P, McGarvey MJ, Makis A, Thomas HC. Mutation preventing formation of hepatitis B e antigen in patients with chronic hepatitis B infection. Lancet ii: 588-591, 1989.
14. Carman WF, Ferrao M, Lok ASF, Ma OCK, Lai CL, Thomas HC. Precore sequence variation in Chinese isolates of hepatitis B virus. J Infect Dis 165: 127-133, 1992.
15. Okamoto H, Yano K, Nozaki Y, Matsui A, Miyazaki H, Yamamoto K, Tsuda F, Machida A, Mishiro S. Mutations within the S gene of hepatitis B virus transmitted from mothers to babies immunized with hepatitis B immune globulin and vaccine. Pediatr Res 32: 264-268, 1992.
16. Yamamoto K, Horikita M, Tsuda F, Itoh K, Akahane Y, Yotsumoto S, Okamoto H, Miyahawa Y, Mayami M. Naturally occurring escape mutants of hepatitis B virus with various mutations in the S gene in carriers seropositive for antibody to hepatitis B surface antigen. J Virol 68: 2671-2676, 1994.
17. Zhang YY, Hansson BG, Kuo LS, Widell A, Nordenfelt E. Hepatitis B virus DNA in serum and liver is commonly found in Chinese patients with chronic liver disease despite the presence of antibodies to HBsAg. Hepatology 17: 538-544, 1993.
18. Montpetit ML, Cassol S, Salas T, O'Shaughnessy MV. Oligscan: a computer program to assist in the design of PCR primers homologous to multiple DNA sequences. J Virol Method 36: 119-128, 1992.
19. Norder H, Hammas B, Löfdahl S, Couroucé AM. Magnius LO. Comparison of the amino acid sequences of nine different serotypes of hepatitis B surface antigen and genomic classification of the corresponding hepatitis B virus strains. J Gen Virol. 73, 1201-1208, 1992.
20. Okamoto H, Tsuda F, Sakugawa H, Sastrosoewignjo R, Imai M, Miyakawa Y, Mayumi M. Typing hepatitis B virus by homology in nucleotide sequence, comparison of surface antigen subtypes. J Gen Virol 69: 2575-2583, 1988.
21. Ono Y, Onda H, Sasada R, Igarashi K, Sugino Y, Nishioka K. The complete nucleotide sequences of the cloned hepatitis B virus DNA; subtype adr and adw. Nucleic Acid Res 11: 1747-1757, 1983.
22. Hopp TP, Wands KR. Prediction of protein antigenic determinants from amino acid sequences. Proc Natl Acad Sci USA 78: 3824-3828, 1981.
23. Radziwill G, Tucker W, Schauer H. Mutational analysis of the hepatitis B virus P gene product: domain structure and RNase H activity. J Virol 64: 613-620, 1991.
24. Brown C, Howard CR, Zuckerman AJ, Steward MW. Affinity of antibody responses in man to hepatitis B vaccine determined with synthetic peptides. Lancet ii: 184-187, 1984.
25. Ionesco-Matieu I, Kennedy RC, Sparrow JT, Culwell AR, Sanchez Y, Melnick JL, Dressman GR. Epitopes associated with a synthetic hepatitis B surface antigen peptide. J Immunol 130: 1947-1952, 1983.
26. Ohnuma H, Takai E, Machida A, Tsuda F ,Okamoto H, Tanaka T, Naito M, Munekata E, Miki K, Miyakawa Y, Mayumi M. Synthetic oligopeptides bearing a common or subtypic determinant of hepatitis B surface antigen. J Immunol 145: 2265-2271, 1990.
27. Prince AM, Ikram H, Hopp TP. Hepatitis B virus vaccine: identification of HBsAg/a and HBsAg/d but not HBsAg/y subtype antigenic determinants on a synthetic immunogenic peptide. Proc Natl Acad Sci USA 79: 579-582, 1982.
28. McMahon G, Ehrlich PH, Moustafa ZA, McCarthy LA, Duttavio D, Tolpin MD, Nadler PI, Ostberg L. Genetic alterations in the gene encoding the major HBsAg: DNA and immunological analysis of recurrent HBsAg derived from monoclonal antibody-treated liver transplant patients. Hepatology 15: 757-766, 1992.
29. Wang GT, Tian GS, Zhang GQ. Sequencing of hepatitis B virus DNA fragment coding major HBsAg of escape mutant. Chung-Hua-Hsueh-Tsa-Chih 74: 335-337, 1994.
30. Chirara MM, Chetsanga CJ. Variant of hepatitis B virus isolated in Zimbabwe. J Med Virol 42: 73-78, 1994.
31. Karthigesu VD, Allison LM, Fortuin M, Mendy M, Whittle HC, Howard CR. A novel hepatitis B virus variant in the sera of immunized children. J Gen Virol 75: 443-448, 1994.
32. Wallace LA, Echevarria JE, Echevarria JM, Carman WF. Molecular characterization of envelope antigenic variant of hepatitia B virus from Spain. J Infect Dis 170: 1300-1304, 1994.