Increased susceptibility of brain slices from carbonic anhydrase II-deficient mice to low [Mg2+]0-induced seizures

Neuroscience Letters

Volumn 207, Issue 3, 1996, Pages 143-146

  Velíšek, Libor ^a,b   Moshé, Solomon L ^a   Stanton, Patrie K ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b CHARLES UNIVERSITY   (Czech Republic)

Author keywords

Acidosis; Carbonic anhydrase; Entorhinal cortex; Epilepsy; Hippocampus; N methyl D aspartate receptors

Indexed keywords

CARBONATE DEHYDRATASE; MAGNESIUM; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; ENTORHINAL CORTEX; EPILEPSY; HIPPOCAMPUS; MOUSE; MUTANT; NONHUMAN; PH; PRIORITY JOURNAL;

ANIMALS; BRAIN; CARBONIC ANHYDRASES; ENTORHINAL CORTEX; HIPPOCAMPUS; MAGNESIUM; MICE; MICE, INBRED STRAINS; REACTION TIME; SEIZURES;

EID: 0029887756     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3940(96)12515-5     Document Type: Article

References (27)

1. Anderson, W.W., Lewis, D.V., Swartzwelder, H.S. and Wilson, W.A., Magnesium-free medium activates seizure-like events in the rat hippocampal slice, Brain Res., 398 (1986) 215-219.
2. Aram, J.A. and Lodge, D., Epileptiform activity induced by alkalosis in rat neocortical slices: block by antagonists of N-methyl-aspartate, Neurosci Lett., 83 (1987) 345-350.
3. Cammer, W. and Zhang, H., Comparison of immunocytochemical staining of astrocytes, oligodendrocytes, and myelinated fibres in the brains of carbonic anhydrase II-deficient mice and normal littermates, J. Neuroimmunol., 34 (1991) 81-86.
4. Cammer, W. and Zhang, H., Carbonic anhydrase in distinct precursors of astrocytes and oligodendrocytes in the forebrains of neonatal and young rats, Brain Res., 67 (1992) 257-263.
5. 2+-induced epileptiform activity in rat temporal cortex slices, Exp. Brain Res., 87 (1991) 581-596.
6. Herron, C.E., Williamson, R. and Collingridge, G.L., A selective N-methyl-D-aspartate antagonist depresses epileptiform activity in rat hippocampal slices, Neurosci. Lett., 61 (1985) 255-260.
7. Jones, R.S.G., Ictal epileptiform events induced by removal of extracellular magnesium in slices of entorhinal cortex are blocked by baclofen, Exp. Neurol., 104 (1989) 155-161.
8. Jones, R.S.G. and Heinemann, U., Synaptic and intrinsic responses of medial entorhinal cortical cells in normal and magnesium-free medium in vitro, J. Neurophysiol., 59 (1988) 1476-1496.
9. Köhr, G. and Heinemann, U., Ketamine and 2-aminophosphono-valerate in the low magnesium epilepsy in rat hippocampal slices, Neurosci. Res. Commun., 1 (1987) 17-21.
10. Lewis, S.E., Erickson, R.P., Barnett, L.B., Venta, P.J. and Tashian, R.E., N-Ethyl-N-nitrosurea null mutation at the mouse Car-2 locus: an animal model for human carbonic anhydrase II deficiency syndrome, Proc. Natl. Acad. Sci. USA, 85 (1988) 1962-1966.
11. Lombroso, C.T. and Forsythe, I., A long-term follow-up of acetazolamide (Diamox) in the treatment of epilepsy, Epilepsia, 1 (1960) 493-500.
12. Maren, T.H., Carbonic anhydrase: chemistry, physiology and inhibition, Physiol. Rev., 47 (1967) 595-781.
13. Mody, I., Lambert, J.D.C. and Heinemann, U., Low extracellular magnesium induces epileptiform activity and spreading depression in rat hippocampal slices, J. Neurophysiol., 57 (1987) 869-888.
14. A receptors, Science, 269 (1995) 977-980.
15. 2+] in combined hippocampal-entorhinal cortex slices: modulation by receptors for norepinephrine and N-methyl-D-aspartate, Epilepsy Res., 1 (1987) 53-62.
16. +, Proc. Natl. Acad. Sci. USA, 87 (1990) 6445-6449.
17. Thomson, A.M., West, D.C. and Lodge, D., An N-methyl-D-aspartate receptor-mediated synapse in rat cerebral cortex: a site of action of ketamine? Nature, 313 (1985) 479-481.
18. Traynelis, S.F. and Cull-Candy, S.G., Proton inhibition of N-methyl-D-aspartate receptors in cerebellar neurons, Nature, 345 (1990) 347-350.
19. + sensitivity of excitatory amino acid receptor channels in rat cerebellar granule neurones, J. Physiol., 433 (1991) 727-763.
20. 2+-induced seizures in combined entorhinal cortex-hippocampal slices, Exp. Brain Res., 101 (1994) 44-52.
21. Velíšek, L., Moshé, S.L. and Stanton, P.K., Resistance of hippocampal synaptic transmission to hypoxia in carbonic anhydrase II-deficient mice, Brain Res., 671 (1995) 245-253.
22. Velíšek, L., Moshé, S.L., Xu, S.-G. and Cammer, W., Reduced susceptibility to seizures in carbonic anhydrase II-deficient mutant mice, Epilepsy Res., 14 (1993) 115-121.
23. Walther, H., Lambert, J.D.C., Jones, R.S.G., Heinemann, U. and Hamon, B., Epileptiform activity in combined slices of the hippocampus, subiculum and entorhinal cortex during perfusion with low magnesium, Neurosci. Lett., 69 (1986) 156-161.
24. Wong, R.K.S. and Prince, D.A., The lateral spread of ictal discharges in neocortical brain slices. Epilepsy Res., 7 (1990) 29-39.
25. Woodbury, D.M., Carbonic anhydrase inhibitors. In G.H. Glaser, J.K. Penry and D.M. Woodbury (Eds.), Antiepileptic Drugs: Mechanisms of Action, Raven Press, New York, 1980, pp. 617-633.
26. Woodbury, D.M. and Karler, R., The role of carbon dioxide in the nervous system, Anesthesiology, 21 (1960) 686-703.
27. Wyllie, E., The Treatment of Epilepsy: Principles and Practice, Lea and Febiger, Philadelphia, 1993, 1238 pp.