Drinking and blood pressure responses to central injection of L-NAME in conscious rats

Physiology and Behavior

Volumn 59, Issue 6, 1996, Pages 1137-1145

  Liu, H ^a   Terrell, M L ^a   Summy Long, J Y ^b   Kadekaro, M ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

Author keywords

AV3V area; Hemorrhage; Hypertonic saline; Hypovolemia; N(G) Nitro L arginine methyl ester; Nitric oxide; Oxytocin; Vasopressin; Water intake

Indexed keywords

N(G) NITRO DEXTRO ARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE INHIBITOR;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLEEDING; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; DOSE RESPONSE; DRINKING BEHAVIOR; ENZYME INHIBITION; FLUID INTAKE; HEMATOCRIT; HYPOTENSION; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; MALE; NEUROMODULATION; NONHUMAN; OSMOSIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT;

EID: 0029887162     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/0031-9384(95)02180-9     Document Type: Article

References (64)

1. Badoer, E.; McKinley, M. J.; Oldfield, B. J.; McAllen, R. M. Distribution of hypothalamic, medullary and lamina terminalis neurons expressing Fos after hemorrhage in conscious rats. Brain Res. 582:323-328; 1992.
2. Badoer, E.; Oldfield, B. J.; McKinley, M. J. Hemorrhage-induced production of Fos in neurons of the lamina terminalis: Role of endogenous angiotensin II. Neurosci. Lett. 159:151-154; 1993.
3. Bains, J. S.; Ferguson, A. V. Paraventricular nucleus neurons projecting to the spinal cord receive excitatory input from the subfornical organ. Am. J. Physiol. 268:R625-R633; 1995.
4. Bredt, D. S.; Glatt, C. E.; Hwang, P. M.; Fotuhi, M.; Dawson, T. M.; Snyder, S. H. Nitric oxide synthase protein and mRNA are discretely localized in neuronal populations of the mammalian CNS together with NADPH diaphorase. Neuron 7:615-624; 1991.
5. Bredt, D. S.; Hwang, P, M.; Snyder, S. H. Localization of nitric oxide synthase indicating a neuronal role for nitric oxide. Nature 347:768-770; 1990
6. Bredt, D. S.; Snyder, S. H. Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum. Proc. Natl. Acad. Sci. USA. 86:9030-9033; 1989.
7. Buggy, J.; Bealer, S. L. Physiological regulation by AV3V region. In: Gross, P. M., ed. Circumventricular organs and body fluids. vol 1. Boca Raton, FL: CRC Press, Inc.; 1987:171-190
8. Cunningham, J. T.; Sullivan, M. J.; Edward, G. L.; Farinpour, R.; Beltz, T. G.; Johnson, A. K. Dissociation of experimentally induced drinking behavior by ibotenate injection into the median preoptic nucleus. Brain Res. 554:153-158; 1991.
9. Dawson, T. M.; Bredt, D. S.; Fotuhi, M.; Hwang, P. M.; Snyder, S. H. Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues. Proc. Natl. Acad. Sci. USA. 88:7797-7801; 1991.
10. Desai, K. M.; Sessa, W. C.; Vane, J. R. Involvement of nitric oxide in the reflex relaxation of the stomach to accommodate food or fluid. Nature 351:477-479; 1991.
11. Di Paola, E. D.; Vidal, M. J.; Nistico, G. L-Glutamate evokes the release of an endothelium-derived relaxing factor-like substance from the rat nucleus tractus solitarius. J. Cardiovasc. Pharmacol. 17(Suppl. 3):S269-S272; 1991.
12. Du, Z-Y.; Dusting, G. J.; Woodman, O. L. Inhibition of nitric oxide synthase specifically enhances adrenergic vasoconstriction in rabbits. Clin. Exp. Pharmacol. Physiol. 19:523-530; 1992.
13. el Karib, A. O.; Sheng, J.; Betz, A. L.; Malvin, R. L. The central effects of a nitric oxide synthase inhibitor (N-omega-nitro-L-arginine) on blood pressure and plasma renin. Clin. and Exper. Hypertension 15(5):819-832; 1993.
14. Forstermann, U.; Gorsky, L. D.; Pollock, J. S.; Schmidt, H. H.; Heller, M.; Murad, F. Regional distribution of EDRF/NO-synthesizing enzyme(s) in rat brain. Biochem. Biophys. Res. Commun. 168(2):727-732; 1990.
15. Garcia-Estan, J.; Carbonell, L. F.; Garcia-Salom, M.; Salazar, F. J.; Quesada, T. Hemodynamic effects of hypertonic saline in the conscious rat. Life Sci. 44:1343-1350; 1989.
16. Garthwaite, J.; Charles, S. L.; Chess-Williams, R. Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain. Nature 336:385-388; 1988.
17. Garthwaite, J. Glutamate, nitric oxide and cell-cell signalling in the nervous system. Trends Neurosci. 14:60-67; 1991.
18. Gutman, M. B.; Jones, D. L.; Ciriello, J. Contribution of nucleus medianus to the drinking and pressor responses to angiotensin II acting at subfomical organ. Brain Res. 488:49-56; 1989.
19. Harada, S.; Tokunaga, S.; Momohara, M.; et al. Inhibition of nitric oxide formation in the nucleus tractus solitarius increase renal sympathetic nerve activity in rabbits. Circ. Res. 72:511-516; 1993.
20. Hatzinikolaou, P.; Gavras, H.; Brunner, H. R.; Gavras I. Role of vasopressin, catecholamines, and plasma volume in hypertonic saline-induced hypertension. Am. J. Physiol. 240:H827-H831; 1981.
21. G-monomethyl-L-arginine to L-citrulline and subsequently to L-arginine. Biochem. Biophys. Res. Commun. 167:1037-1043; 1990.
22. Herbert, J.; Forsling, M. L.; Howes, S. R.; Stacey, P. M.; Shiers, H. M. Regional expression of c-fos antigen in the basal forebrain following intraventricular infusions of angiotensin and its modulation by drinking either water or saline. Neuroscience 51(4):867-882; 1992.
23. Honda, K.; Negoro, H.; Dyball, R. E. J.; Higuchi, T.; Takano, S. The osmoreceptor complex in the rat: Evidence for interactions between the supraoptic and other diencephalic nuclei. J. Physiol. (Lond.) 431:225-241; 1990.
24. Horn, T.; Smith, P. M.; McLaughlin, B. E.; Bauce, L.; Marks, G. S.; Pittman, Q. J.; Ferguson, A. V. Nitric oxide actions in paraventricular nucleus: cardiovascular and neurochemical implications. Am. J. Physiol. 266:R306-R313; 1994.
25. Iadecola, C.; Pelligrino, D. A.; Moskowitz, M. A.; Lassen, N. A. Nitric oxide synthase inhibition and cerebrovascular regulation. J. Cereb. Blood Flow Metab. 14:175-192; 1994.
26. Ignarro, L. J.; Buga, G. M.; Wood, K. S.; Byrns, R. E.; Chaudhuri, G. Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc. Natl. Acad. Sci. USA 84:9265-9269; 1987.
27. Johnson, A. K. The periventricular anteroventral third ventricle (AV3V): Its relationship with the subfornical organ and neural systems involved in maintaining body fluid homeostasis. Brain Res. Bull. 15(6):595-601; 1985.
28. Kadekaro, M.; Summy-Long, J. Y.; Harris, J. S.; Terrell, M. L.; Freeman, S.; Eisenberg, H. M. Cerebral metabolic and vasopressin and oxytocin responses during osmotic stimulation in conscious rats. J. Neuroendocrinol. 4(2):217-222; 1992.
29. Kadekaro, M.; Terrell, M. L.; Harmann, P.; Summy-Long, J. Y. Central inhibition of nitric oxide synthase attenuates water intake but does not alter enhanced glucose utilization in the hypothalamo-neurohypophysial system of dehydrated rats. Neurosci. Lett. 173:115-118; 1994.
30. Kadowaki, K.; Kishimoto, J.; Leng, G.; Emson, P. C. Up-regulation of nitric oxide synthase (NOS) gene expression together with NOS activity in the rat hypothalamo-hypophysial system after chronic salt loading: Evidence of a neuromodulatory role of nitric oxide in arginine vasopressin and oxytocin secretion. Endocrinology 134:1011-1017; 1994.
31. Lind, R. W. Neural connections. In: Gross, P. M., ed. Circumventricular organs and body fluids, vol. 1., Boca Raton, FL: CRC Press Inc.; 1987:27-42.
32. Lorsbach, R. B.; Russell, S. W. A specific sequence of stimulation is required to induce synthesis of the antimicrobial molecule nitric oxide by mouse macrophages. Infect. Immun. 60:2133-2135; 1992.
33. McKinley, M. J.; Bicknell, R. J.; Hards, D.; et al. Efferent neural pathways of the lamina terminalis subserving osmoregulation. Prog. Brain Res. 91:395-402; 1992.
34. Michel, T.; Smith, T. W. Nitric oxide synthases and cardiovascular signaling. Am. J. Cardiol. 72:33C-38C; 1993.
35. Miselis, R. R. The efferent projections of the subfornical organ of the rat: A circumventricular organ within a neural network subserving water balance. Brain Res. 230:1-23; 1981.
36. Oldfield, B. J.; Bicknell, R. J.; McAllen, R. M.; Weisinger, R. S.; McKinley, M. J. Intravenous hypertonic saline induces Fos immunoreactivity in neurons throughout the lamina terminalis. Brain Res. 561:151-156; 1991.
37. Oldfield, B. J.; Hards, D. K.; McKinley, M. J. Neurons in the median preoptic nucleus of the rat with collateral branches to the subfornical organ and supraoptic nucleus. Brain Res. 586:86-90; 1992.
38. Palmer, R. M.; Ferrige, A. G.; Moncada, S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 327:524-526; 1987.
39. Phillips, M. I.; Camacho, A. Neural connections of the organum vasculosum of the lamina terminalis. In: Gross, P. M., ed. Circumventricular organs and body fluids. vol. 1. Boca Raton, FL: CRC Press, Inc.; 1987:157-169
40. Pow, D. V. NADPH-diaphorase (nitric oxide synthase) staining in the rat supraoptic nucleus is activity dependent: Possible functional implications. J. Neuroendocrinol. 4(4):377-380; 1992.
41. Rees, D. D.; Palmer, R. M.; Moncada, S. Role of endothelium-derived nitric oxide in the regulation of blood pressure. Proc. Natl. Acad. Sci. USA 86:3375-3378; 1989.
42. Ricardo, J. A.; Koh, E. T. Anatomical evidence of direct projections from the nucleus of the solitary tract to the hypothalamus, amygdala, and other forebrain structures in the rat. Brain Res. 153:1-26; 1978.
43. Rolls, B. J.; Rolls, E. T. Thirst. New York: Cambridge University Press; 1982.
44. Rosenblum, W. I.; Nishimura, H.; Nelson, G. H. L-NMMA in brain microcirculation of mice is inhibited by blockade of cyclooxygenase and by superoxide dismutase. Am. J. Physiol. 262:H1343-H1349; 1992.
45. Russell, P. J. D.; Abdelaal, A. E.; Mogenson, G. J. Graded levels of hemorrhage, thirst and angiotensin II in the rat. Physiol. Behav. 15:117-119; 1975.
46. G-Methyl-L-arginine, an inhibitor of L-arginine derived nitric oxide synthesis, stimulates renal sympathetic nerve activity in vivo. Circ. Res. 70:607-611; 1992.
47. G-monomethyl-L-arginine on renal sympathetic nerve activity in anaesthetized rats. In: Moncada, S.; Higgs, E. A., eds. Nitric oxide from L-arginine: A bioregulatory system. Amsterdam: Elsevier; 1990:493-494.
48. Schmidt, H. H.; Gagne, C. D.; Nakane, M.; Pollock, J. S.; Miller, M. F.; Murad, F. Mapping of neural nitric oxide synthase in the rat suggests frequent co-localization with NADPH diaphorase but not with soluble guanylyl cyclase, and novel paraneural functions for nitrinergic signal transduction. J. Histochem. Cytochem. 40:1439-1456; 1992.
49. Schuman, E. M.; Madison, D. V. A requirement for the intercellular messenger nitric oxide in long-term potentiation. Science 254:1503-1506; 1991.
50. Shibuki, K.; Okada, D. Endogenous nitric oxide release required for long-term synaptic depression in the cerebellum. Nature 349:326-328; 1991.
51. Sibbald, J. R.; Hubbard, J. I.; Sirrett, N. E. Responses from the osmosensitive neurons of the rat subfornical organ in vitro. Brain Res. 461:205-214; 1988.
52. Springall, D. R.; Riveros-Moreno, V.; Buttery, L.; et al. Immunological detection of nitric oxide synthase(s) in human tissues using heterologous antibodies suggesting different isoforms. Histochemistry 98:259-266; 1992.
53. Sved, A. F.; Gordon, F. J. Amino acids as central neurotransmitters in the baroreceptor reflex pathway. NIPS 9:243-246; 1994.
54. Summy-Long, J. Y.; Bui, V.; Mantz, S.; Koehler, E.; Weisz, J.; Kadekaro, M. Central inhibition of nitric oxide preferentially augments release of oxytocin during dehydration. Neurosci. Lett. 152:190-193; 1993
55. Summy-Long, J. Y.; Salisbury, R.; Marietta, M. P.; Hartman, R. D.; Weisz, J. Pathways of hydrogen utilization from NADPH generated by glucose-6-phosphate dehydrogenase in circumventricular organs and the hypothalamo-neurohypophysial system: A cytochemical study. Brain Res. 294:23-35; 1984.
56. W-nitro-L-arginine methyl on pressor responses elicited by sympathetic nerve stimulation in pithed normotensive and hypertensive rats. Life Sci. 49:1989-1995; 1991.
57. Talman, W. T.; Granata, A. R.; Reis, D. J. Glutamatergic mechanisms in the nucleus tractus solitarius in blood pressure control. Fed. Proc. 43:39-44; 1984.
58. Tanaka, J.; Seto, K. Neurons in the nucleus of the solitary tract with ascending projections to the subfornical organ in the rat. Neurosci. Lett. 89:152-155; 1988.
59. Villar, M. J.; Ceccatelli, S.; Ronnqvist, M.; Hokfelt, T. Nitric oxide synthase increases in hypothalamic magnocellular neurons after salt loading in the rat. An immunohistochemical and in situ hybridization study. Brain Res. 644:273-281; 1994.
60. Vincent, S. R.; Kimura, H. Histochemical mapping of nitric oxide synthase in the rat brain. Neuroscience 46:755-784; 1992.
61. Welch, G.; Loscalzo, J. Nitric oxide and the cardiovascular system. J. Card. Surg. 9:361-371; 1994.
62. Young, H. M.; Furness, J. B.; Shuttleworth, C. W.; Bredt, D. S.; Snyder, S. H. Co-localization of nitric oxide synthase immunoreactivity and NADPH diaphorase staining in neurons of the guinea-pig intestine. Histochemistry 97:375-378; 1992.
63. Zardetto-Smith, A. M.; Gray, T. S. A direct neural projection from the nucleus of the solitary tract to the subfornical organ in the rat. Neurosci. Lett. 80:163-166; 1987.
64. Zardetto-Smith, A. M.; Thunhorst, R. L.; Cicha, M. Z.; Johnson, A. K. Afferent signaling and forebrain mechanisms in the behavioral control of extracellular fluid volume. Ann. NY Acad. Sci. 689(1):161-176; 1993.