메뉴 건너뛰기




Volumn 44, Issue 6, 1996, Pages 571-579

Dihydrorhodamine 123 identifies impaired mitochondrial respiratory chain function in cultured cells harboring mitochondrial DNA mutations

Author keywords

Cybrid and hybrid cultures; Cytochrome c oxidase; Dihydrorhodamine 123; Fluorescence microscopy; Human mitochondrial encephalomyopathies; Mitochondrial DNA mutations; Respiratory chain; Rhodamine 123

Indexed keywords

FLUORESCENT DYE; MITOCHONDRIAL DNA; RHODAMINE 123;

EID: 0029886977     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1177/44.6.8666742     Document Type: Article
Times cited : (26)

References (51)
  • 3
    • 0026621445 scopus 로고
    • 1ys mutation in skeletal muscle of patients with myoclonic epilepsy and ragged-red fibers (MERRF)
    • 1ys mutation in skeletal muscle of patients with myoclonic epilepsy and ragged-red fibers (MERRF). Am J Hum Genet 51:1187-1200
    • (1992) Am J Hum Genet , vol.51 , pp. 1187-1200
    • Boulet, L.1    Karpati, G.2    Shoubridge, E.A.3
  • 4
    • 0026608057 scopus 로고
    • MELAS mutation in mtDNA binding site for transcription termination factor causes defects in protein synthesis and in respiration but not changes in levels of upstream and downstream mature transcripts
    • Chomyn A, Martinuzzi A, Yoneda M, Daga A, Hurko O, Johns D, Lai ST, Nonaka I, Angelini C, Attardi G (1992) MELAS mutation in mtDNA binding site for transcription termination factor causes defects in protein synthesis and in respiration but not changes in levels of upstream and downstream mature transcripts. Proc Natl Acad Sci USA 89:4221-4225
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 4221-4225
    • Chomyn, A.1    Martinuzzi, A.2    Yoneda, M.3    Daga, A.4    Hurko, O.5    Johns, D.6    Lai, S.T.7    Nonaka, I.8    Angelini, C.9    Attardi, G.10
  • 5
    • 0025968499 scopus 로고
    • In vitro genetic transfer of protein synthesis and respiration defects to mitochondrial DNA-less cells with myopathy-patient mitochondria
    • Chomyn A, Meola G, Bresolin N, Lai ST, Scarlato G, Attardi G (1991) In vitro genetic transfer of protein synthesis and respiration defects to mitochondrial DNA-less cells with myopathy-patient mitochondria. Mol Cell Biol 11:2236-2244
    • (1991) Mol Cell Biol , vol.11 , pp. 2236-2244
    • Chomyn, A.1    Meola, G.2    Bresolin, N.3    Lai, S.T.4    Scarlato, G.5    Attardi, G.6
  • 6
    • 0021966704 scopus 로고
    • Ethidium bromide-induced loss of mitochondrial DNA from primary chicken embryo fibroblasts
    • Desjardins P, Frost E, Morais R (1985) Ethidium bromide-induced loss of mitochondrial DNA from primary chicken embryo fibroblasts. Mol Cell Biol 5:1163-1169
    • (1985) Mol Cell Biol , vol.5 , pp. 1163-1169
    • Desjardins, P.1    Frost, E.2    Morais, R.3
  • 7
    • 0029079541 scopus 로고
    • Different cellular backgrounds confer a marked advantage to either mutant or wild-type mitochondrial genomes
    • Dunbar DR, Moonie PA, Jacobs HT, Holt IJ (1995) Different cellular backgrounds confer a marked advantage to either mutant or wild-type mitochondrial genomes. Proc Natl Acad Sci USA 92:6562-6566
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 6562-6566
    • Dunbar, D.R.1    Moonie, P.A.2    Jacobs, H.T.3    Holt, I.J.4
  • 8
    • 0022492812 scopus 로고
    • Rhodamine 123 is a probe of transmembrane potential in isolated rat-liver mitochondria: Special and metabolic properties
    • Emaus RK, Grünwald R, Lemaster J (1986) Rhodamine 123 is a probe of transmembrane potential in isolated rat-liver mitochondria: special and metabolic properties. Biochim Biophys Acta 850:436-448
    • (1986) Biochim Biophys Acta , vol.850 , pp. 436-448
    • Emaus, R.K.1    Grünwald, R.2    Lemaster, J.3
  • 9
    • 0025294129 scopus 로고
    • A fast and easy method to determine the production of reactive oxygen intermediates by human and murine phagocytes using dihydtothodamine 123
    • Emmendörffer A, Hecht M, Lohmann-Matthes M-L, Roesler J (1990) A fast and easy method to determine the production of reactive oxygen intermediates by human and murine phagocytes using dihydtothodamine 123, J Immunol Methods 131:269-275
    • (1990) J Immunol Methods , vol.131 , pp. 269-275
    • Emmendörffer, A.1    Hecht, M.2    Lohmann-Matthes, M.-L.3    Roesler, J.4
  • 10
    • 0001698695 scopus 로고
    • Rapid examination of muscle tissue: An improved trichrome stain method for fresh frozen biopsy sections
    • Engel WK, Cunningham CG (1963) Rapid examination of muscle tissue: an improved trichrome stain method for fresh frozen biopsy sections. Neurology 13:919-923
    • (1963) Neurology , vol.13 , pp. 919-923
    • Engel, W.K.1    Cunningham, C.G.2
  • 12
    • 0025666322 scopus 로고
    • Leu(UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies
    • Leu(UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies. Nature 348:651-653
    • (1990) Nature , vol.348 , pp. 651-653
    • Goto, Y.1    Nonaka, I.2    Horai, S.3
  • 13
    • 0025836655 scopus 로고
    • Introduction of disease-related mitochondrial DNA deletions into HeLa cells lacking mitochondrial DNA results in mitochondrial dysfunction
    • Hayashi J-I, Ohta S, Kikuchi A, Takemitsu M, Goto Y-I, Nonaka I (1991) Introduction of disease-related mitochondrial DNA deletions into HeLa cells lacking mitochondrial DNA results in mitochondrial dysfunction. Proc Natl Acad Sci USA 88:10614-106118
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 10614-106118
    • Hayashi, J.-I.1    Ohta, S.2    Kikuchi, A.3    Takemitsu, M.4    Goto, Y.-I.5    Nonaka, I.6
  • 14
    • 0027430156 scopus 로고
    • Dihydrorhodamine 123 a fluorescent probe for superoxide generation?
    • Henderson LM, Chappell JB (1993) Dihydrorhodamine 123 a fluorescent probe for superoxide generation? Eur J Biochem 217:973-980
    • (1993) Eur J Biochem , vol.217 , pp. 973-980
    • Henderson, L.M.1    Chappell, J.B.2
  • 15
    • 0023883150 scopus 로고
    • Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies
    • Holt IJ, Harding AE, Morgan-Hughes JA (1988) Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies. Nature 331:717-719
    • (1988) Nature , vol.331 , pp. 717-719
    • Holt, I.J.1    Harding, A.E.2    Morgan-Hughes, J.A.3
  • 16
    • 0007574262 scopus 로고
    • Localization of mitochondria in living cells with rhodamine 123
    • Johnson LV, Walsh ML, Chen LB (1980) Localization of mitochondria in living cells with rhodamine 123. Proc Natl Acad Sci USA 77:990-994
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 990-994
    • Johnson, L.V.1    Walsh, M.L.2    Chen, L.B.3
  • 17
    • 0024448458 scopus 로고
    • Human cells lacking mtDNA: Repopulation with exogenous mitochondria by complementation
    • King MP, Attardi G (1989) Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation. Science 246:500-503
    • (1989) Science , vol.246 , pp. 500-503
    • King, M.P.1    Attardi, G.2
  • 18
    • 0026573082 scopus 로고
    • Leu(UUR) mutation associated with mitochondrial myopathy, encephalopathy, lactic acidosis and strokelike episodes
    • Leu(UUR) mutation associated with mitochondrial myopathy, encephalopathy, lactic acidosis and strokelike episodes. Mol Cell Biol 12:480-490
    • (1992) Mol Cell Biol , vol.12 , pp. 480-490
    • King, M.P.1    Koga, Y.2    Davidson, M.3    Schon, E.A.4
  • 20
    • 0023877476 scopus 로고
    • Kearns-Sayre syndrome with muscle mitochondrial DNA deletion
    • Lestienne P, Ponsot G (1988) Kearns-Sayre syndrome with muscle mitochondrial DNA deletion. Lancet 1:885
    • (1988) Lancet , vol.1 , pp. 885
    • Lestienne, P.1    Ponsot, G.2
  • 22
    • 0022555796 scopus 로고
    • Measurement of the effect of interferons on cellular differentiation of human skeletal muscle cells
    • Pestka S, ed. New York, Academic Press
    • Miranda AF, Babiss LE, Fisher PB (1986) Measurement of the effect of interferons on cellular differentiation of human skeletal muscle cells. In Pestka S, ed. Methods in Enzymology. Vol 119. Part c. Interferons. New York, Academic Press, 619-628
    • (1986) Methods in Enzymology. Vol 119. Part C. Interferons , vol.119 , pp. 619-628
    • Miranda, A.F.1    Babiss, L.E.2    Fisher, P.B.3
  • 23
    • 0024556632 scopus 로고
    • Cytochrome c oxidase deficiency in Leigh syndrome: Genetic evidence for a nuclear DNA-encoded mutation
    • Miranda AF, Ishii S, DiMauro S, Shay JW (1989) Cytochrome c oxidase deficiency in Leigh syndrome: genetic evidence for a nuclear DNA-encoded mutation. Neurology 39:697-702
    • (1989) Neurology , vol.39 , pp. 697-702
    • Miranda, A.F.1    Ishii, S.2    DiMauro, S.3    Shay, J.W.4
  • 25
    • 0001853416 scopus 로고
    • Mitochondrial diseases: Toward a rational classification
    • Appel SH, ed. St Louis, Mosby Yearbook
    • Moraes CT, Schon EA, DiMauro S (1991) Mitochondrial diseases: toward a rational classification. In Appel SH, ed. Current Neurology. Vol 11. St Louis, Mosby Yearbook, 83-119
    • (1991) Current Neurology , vol.11 , pp. 83-119
    • Moraes, C.T.1    Schon, E.A.2    DiMauro, S.3
  • 26
    • 0024321834 scopus 로고
    • Heteroplasmy of mitochondrial genomes in clonal cultures from patients with Kearns-Sayre syndrome
    • Moraes CT, Schon EA, DiMauro S, Miranda AF (1989b) Heteroplasmy of mitochondrial genomes in clonal cultures from patients with Kearns-Sayre syndrome. Biochem Biophys Res Common 160:765-771
    • (1989) Biochem Biophys Res Common , vol.160 , pp. 765-771
    • Moraes, C.T.1    Schon, E.A.2    DiMauro, S.3    Miranda, A.F.4
  • 27
    • 0024499802 scopus 로고
    • Duplications of mitochondrial DNA in mitochondrial myopathy
    • Poulton J, Deadman ME, Gardiner RM (1989) Duplications of mitochondrial DNA in mitochondrial myopathy. Lancet 1:236-240
    • (1989) Lancet , vol.1 , pp. 236-240
    • Poulton, J.1    Deadman, M.E.2    Gardiner, R.M.3
  • 28
    • 0025865138 scopus 로고
    • Flow cytometric measurement of the respiratory burst activity of phagocytes using dihydrorhodamine 123
    • Rothe G, Emmendörffer A, Oser A, Roesler J, Valet G (1991) Flow cytometric measurement of the respiratory burst activity of phagocytes using dihydrorhodamine 123. J Immunol Methods 138:133-135
    • (1991) J Immunol Methods , vol.138 , pp. 133-135
    • Rothe, G.1    Emmendörffer, A.2    Oser, A.3    Roesler, J.4    Valet, G.5
  • 29
    • 0023683450 scopus 로고
    • Dihydrorhodamine 123: A new flow cytometric indicator for respiratory burst activity in neutrophil granulocytes
    • Rothe G, Oser A, Valet G (1988) Dihydrorhodamine 123: a new flow cytometric indicator for respiratory burst activity in neutrophil granulocytes. Naturwissenschaften 75:354-355
    • (1988) Naturwissenschaften , vol.75 , pp. 354-355
    • Rothe, G.1    Oser, A.2    Valet, G.3
  • 30
    • 84889505488 scopus 로고
    • Flow cytometric characterization of oxidative processes in neutrophils and monocytes with dihydrorhodamine 123, 2′,7′ dichlorofluorescein and hydroethidine
    • Burger G, Oberholzer M, Vooijs GP, eds. Amsterdam, Elsevier Science Publishers
    • Rothe G, Valet G (1990) Flow cytometric characterization of oxidative processes in neutrophils and monocytes with dihydrorhodamine 123, 2′,7′ dichlorofluorescein and hydroethidine. In Burger G, Oberholzer M, Vooijs GP, eds. Advances in Analytical Cellular Pathology. Amsterdam, Elsevier Science Publishers, 313-314
    • (1990) Advances in Analytical Cellular Pathology , pp. 313-314
    • Rothe, G.1    Valet, G.2
  • 32
    • 0027087413 scopus 로고
    • Structural and functional mitochondrial abnormalities associated with high levels of partially deleted mitochondrial DNAs in somatic cell hybrids
    • Sancho S, Moraes CT, Tanji K, Miranda AF (1992) Structural and functional mitochondrial abnormalities associated with high levels of partially deleted mitochondrial DNAs in somatic cell hybrids. Somat Cell Mol Genet 18:431-442
    • (1992) Somat Cell Mol Genet , vol.18 , pp. 431-442
    • Sancho, S.1    Moraes, C.T.2    Tanji, K.3    Miranda, A.F.4
  • 33
    • 0024596946 scopus 로고
    • A direct repeat is a hotspot for large-scale deletion of human mitochondrial DNA
    • Schon EA, Rizzuto R, Moraes CT, Nakase H, Zeviani M, DiMauro S (1989) A direct repeat is a hotspot for large-scale deletion of human mitochondrial DNA. Science 244:346-349
    • (1989) Science , vol.244 , pp. 346-349
    • Schon, E.A.1    Rizzuto, R.2    Moraes, C.T.3    Nakase, H.4    Zeviani, M.5    DiMauro, S.6
  • 34
    • 0014311556 scopus 로고
    • Nondroplet ultrastructural demonstration of cytochrome oxidase activity with a polymerizing osmiophilic reagent, diaminobenzidine (DAB)
    • Seligman AM, Karnovsky MJ, Wasserkrug HL, Hanker JS (1968) Nondroplet ultrastructural demonstration of cytochrome oxidase activity with a polymerizing osmiophilic reagent, diaminobenzidine (DAB). J Cell Biol 38:1-14
    • (1968) J Cell Biol , vol.38 , pp. 1-14
    • Seligman, A.M.1    Karnovsky, M.J.2    Wasserkrug, H.L.3    Hanker, J.S.4
  • 35
    • 0000152586 scopus 로고
    • The histochemical demonstration of succinic dehydrogenase
    • Seligman AM, Rutenberg AM (1951) The histochemical demonstration of succinic dehydrogenase. Science 113:317-320
    • (1951) Science , vol.113 , pp. 317-320
    • Seligman, A.M.1    Rutenberg, A.M.2
  • 37
    • 0025313091 scopus 로고
    • Unexpected non-random mitochondrial DNA segregation in human cell hybrids
    • Shay JW, Ishii S (1990) Unexpected non-random mitochondrial DNA segregation in human cell hybrids. Anticancer Res 10:279-284
    • (1990) Anticancer Res , vol.10 , pp. 279-284
    • Shay, J.W.1    Ishii, S.2
  • 39
    • 0028037791 scopus 로고
    • Oxidative phosphorylation diseases and mitochondrial DNA mutations: Diagnosis and treatment
    • Shoffner JM, Wallace DC (1994) Oxidative phosphorylation diseases and mitochondrial DNA mutations: diagnosis and treatment. Annu Rev Nutr 14:535-568
    • (1994) Annu Rev Nutr , vol.14 , pp. 535-568
    • Shoffner, J.M.1    Wallace, D.C.2
  • 40
    • 0025371499 scopus 로고
    • Oxidative phosphorylation diseases: Disorders of two genomes
    • Harris H, Hirschhorn K, eds. New York, Plenum Press
    • Shoffner JM, Wallace DC (1990) Oxidative phosphorylation diseases: disorders of two genomes. In Harris H, Hirschhorn K, eds. Advances in Human Genetics. Vol 19. New York, Plenum Press, 267-330
    • (1990) Advances in Human Genetics , vol.19 , pp. 267-330
    • Shoffner, J.M.1    Wallace, D.C.2
  • 44
    • 0027936218 scopus 로고
    • Cytoplasmic transfer of the mtDNA nt 8993 T → G (ATP6) point mutation associated with Leigh syndrome into mtDNA-less cells demonstrates cosegregation with a decrease in state III respiration and ADP/O ratio
    • Trounce I, Neill S, Wallace DC (1994) Cytoplasmic transfer of the mtDNA nt 8993 T → G (ATP6) point mutation associated with Leigh syndrome into mtDNA-less cells demonstrates cosegregation with a decrease in state III respiration and ADP/O ratio. Proc Natl Acad Sci USA 91:8334-8338
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8334-8338
    • Trounce, I.1    Neill, S.2    Wallace, D.C.3
  • 45
    • 0026624980 scopus 로고
    • Diseases of the mitochondrial DNA
    • Wallace DC (1992) Diseases of the mitochondrial DNA. Annu Rev Biochem 61:1175-1212
    • (1992) Annu Rev Biochem , vol.61 , pp. 1175-1212
    • Wallace, D.C.1
  • 46
    • 0022652982 scopus 로고
    • Mitotic segregation of mitochondrial DNAs in human cell hybrids and expression of chloramphenicol resistance
    • Wallace DC (1986) Mitotic segregation of mitochondrial DNAs in human cell hybrids and expression of chloramphenicol resistance. Somat Cell Mol Genet 12:41-49
    • (1986) Somat Cell Mol Genet , vol.12 , pp. 41-49
    • Wallace, D.C.1
  • 48
    • 0026457825 scopus 로고
    • Marked replicative advantage of human mtDNA carrying a point mutation that causes the MELAS encephalopathy
    • Yoneda M, Chomyn A, Martinuzzi A, Hurko O, Attardi G (1992) Marked replicative advantage of human mtDNA carrying a point mutation that causes the MELAS encephalopathy. Proc Natl Acad Sci USA 89:11164-11168
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 11164-11168
    • Yoneda, M.1    Chomyn, A.2    Martinuzzi, A.3    Hurko, O.4    Attardi, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.