Immunization with T cell receptor Vβ chain peptides deletes pathogenic T cells and prevents the induction of collagen-induced arthritis in mice

Journal of Clinical Investigation

Volumn 97, Issue 12, 1996, Pages 2849-2858

  Haqqi, Tariq M ^a,b   Qu, Xue Mei ^a   Anthony, Donald ^a   Ma, Jing ^b   Sy, Man Sun ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

animal model; inflammation; polymerase chain reaction; T cell receptor; vaccination

Indexed keywords

COLLAGEN; COLLAGEN TYPE 2; FREUND ADJUVANT; RECEPTOR ANTIBODY; SYNTHETIC PEPTIDE; T LYMPHOCYTE RECEPTOR BETA CHAIN;

ADOPTIVE TRANSFER; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE EROSION; CONTROLLED STUDY; GENE EXPRESSION; HUMORAL IMMUNITY; HYPERPLASIA; IMMUNIZATION; INTRADERMAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; MOUSE; NONHUMAN; PANNUS; POLYARTHRITIS; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0029886958     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118741     Document Type: Article

References (20)

1. Haqqi, T.M., and C.S. David. 1990. T cell receptor Vβ gene repertoire in mice: Possible role in resistance and susceptibility to type-II collagen induced arthritis. J. Autoimmun. 3:113-121.
2. Holmdahl, R., V. Malmstrom, and E. Vuorio. 1993. Autoimmune recognition of cartilage collagens. Ann. Med. 25:251-264.
3. Holmdahl, R., M. Andersson, T.J. Goldschmidt, K. Gustaffson, L. Jansson, and J. A. Mo. 1990. Type-II collagen autoimmunity in animals and provocations leading to arthritis. Immunol. Rev. 118:193-232.
4. Myers, L.K., J.M. Stuart, and A.H. Kang. 1989. A CD4 cell is capable of transforming suppression of collagen induced arthritis. J. Immunol. 143:3976-3980.
5. Haqqi, T.M., G.D. Anderson, S. Banerjee, and C.S. David. 1992. Restricted heterogeneity in T cell antigen receptor Vβ gene usage in the lymph nodes and arthritic joints of mice. Proc. Natl. Acad. Sci. USA. 89:1253-1255.
6. Osman, G.E., M. Toda, O. Kanigawa, and L.E. Hood. 1993. Characterization of the T cell receptor repertoire causing collagen arthritis in mice. J. Exp. Med. 177:387-395.
7. Acha-Orbea, H., D.J. Mitchell, L. Timmermann, D. Wraith, G.S. Tausch, M.K. Waldor, S.S. Zamvil, H.O. McDevitt, and L. Steinman. 1988. Limited heterogeneity of T cell receptors from lymphocytes mediating autoimmune encephalomyelitis allows specific immune intervention. Cell. 54:263-273.
8. Urban, J.L., V. Kumar, D.H. Kono, C. Gomez, S.J. Horvath, J. Clayton, D.G. Ando, E.E. Sercarz, and L. Hood. 1988. Restricted use of T cell receptor V genes in murine autoimmune encephalomyelitis raises possibilities for antibody therapy. Cell. 54:577-592.
9. Vandenbark, A.A., G.A. Hashim, and H. Offner. 1989. Immunization with a synthetic T cell receptor V region peptide protects against experimental autoimmune encephalomyelitis. Nature (Lond.). 341:541-544.
10. Offner, H., G.A. Hashim, and A.A. Vandenbark. 1991. T cell receptor peptide therapy triggers autoregulation of experimental encephalomyelitis. Science (Wash. DC). 251:430-432.
11. -) that is susceptible to collagen induced arthritis. J. Immunol. 152:4175-4182.
12. q) mouse strain-BUB/BnJ-with collagen induced arthritis. J. Autoimmun. 20:163-170.
13. Margalit, H., J.L. Sponge, J.L. Cornett, K.P. Cease, C. Delisi, and J.A. Berzofsky. 1987. Prediction of immunodominant helper T cell antigenic sites from the primary sequence. J. Immunol. 138:2213-2229.
14. Rothbard, J.B., and W.R. Taylor. 1988. A sequence pattern common to T cell epitopes. EMBO. (Eur. Mol. Bio. Organ.) J. 7:93-102.
15. Banerjee, S., T.M. Haqqi, H.S. Luthra, J.M. Stuart, and C.S. David. 1988. Possible role of Vβ T cell receptor genes in susceptibility to collagen-induced arthritis in mice. J. Exp. Med 167:832-839.
16. Durie, F.H., R.A. Fava, T.M. Foy, A. Aruffo, J.A. Ledbetter, and R.J. Noelle. 1993. Prevention of collagen induced arthritis with an antibody to gp39, the ligand for CD 40. Science (Wash. DC). 261:1328-1330.
17. Matsuoka, N., N. Bernard, E.S. Concepcion, P.N. Graves. A. Ben-Nun, and T. F. Davies. 1993. T-cell receptor V region β-chain gene expression in the autoimmune thyroiditis of non-obese diabetic mice. J. Immunol. 151:1691-1701.
18. Goss, J.A., M.A. Alexander-Miller, J. Gorka, M.W. Flye, J.M. Conolly, and T.H. Hansen. 1993. Specific prolongation of allograft survival by a T cell receptor derived peptide. Proc. Natl. Acad. Sci. USA. 90:9872-9876.
19. Broeren, P.M., M.A. Lucassen, M.J.B. van Stipdonk, R. van der Zee, C.J.P. Boog, J.G. Kusters, and W. van Eden. 1994. CDR1 T-cell receptor β-chain peptide induces major histocompatibility complex class Iirestricted T-T cell interactions. Proc. Natl. Acad. Sci. USA. 91:5997-6001.
20. Stuart, J.M., W.C. Watson, and A.H. Kang. 1988. Collagen autoimmunity and arthritis. FASEB (Fed. Am. Soc. Exp. Biol.) J. 2:2950-2956.