HIV-1 envelope glycoprotein gp120 down-regulates CD4 expression in primary human macrophages through induction of endogenous tumour necrosis factor-α

Immunology

Volumn 88, Issue 1, 1996, Pages 55-60

  Karsten, V ^a   Gordon, S ^b   Kirn, A ^a   Herbein, G ^a,c  

^a INSERM   (France)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c PICOWER INST FOR MEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; CD4 ANTIGEN; GLYCOPROTEIN GP 120; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; DOWN REGULATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MACROPHAGE; NORMAL HUMAN; PRIORITY JOURNAL;

EID: 0029886827     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.1996.d01-648.x     Document Type: Article

References (30)

1. CLERICI M. & SHEARER G.M. (1993) A TH1-TH2 switch is a critical step in the etiology of HIV infection. Immunol Today 14, 107.
2. FAUCI A.S. (1993) Multifactorial nature of human immunodeficiency virus disease: implications for therapy. Science 262, 1011.
3. CLERICI M., SARIN A., COFFMAN R.L. et al. (1994) Type 1/type 2 cytokine modulation of T-cell programmed cell death as a model for human immunodeficiency virus pathogenesis. Proc Natl Acad Sci USA 91, 11811.
4. OH S.K., CRUIKSHANK W.W., RAINA J. et al. (1992) Identification of HIV-1 envelope glycoprotein in the serum of AIDS and ARC patients. J Acquir Immune Defic Syndr 5, 251.
5. WAHL L.M., CONCORAN M.L., PYLE S.W., ARTHUR L.O., HARELBELLAN A. & FARRAR W.L. (1989) Human immunodeficiency virus glycoprotein (gp120) induction of monocyte arachidonic acid metabolites and interleukin 1. Proc Natl Acad Sci USA 86, 621.
6. MERRIL J.E., KOYANAGI Y. & CHEN I.S.Y. (1989) Interleukin-1 and tumor necrosis factor alpha can be induced from mononuclear phagocytes by human immunodeficiency virus type 1 binding to the CD4 receptor. J Virol 63, 4404.
7. CLOUSE K.A., COSENTINO L.M., WEITH K.A. et al. (1991) The HIV-1 gp120 envelope protein has the intrinsic capacity to stimulate monokine secretion. J Immunol 147, 2892.
8. CAPOBIANCHI M.R., AMEGLIO F., CORDIALI FEI P. et al. (1993) Coordinate induction of interferon-alpha and -gamma by recombinant HIV-1 glycoprotein 120. AIDS Res Hum Retroviruses 9, 957.
9. SZEBENI J., DIEFFENBACH C., WAHL S.M. et al. (1991) Induction of alpha interferon by human immunodeficiency virus type 1 in human monocyte-macrophage cultures. J Virol 65, 6362.
10. HERBEIN G., KESHAV S., COLLIN M., MONTANER L.J. & GORDON S. (1994) HIV-1 induces tumour necrosis factor and interleukin-1 gene expression in primary human macrophages independent of productive infection. Clin Exp Immunol 95, 442.
11. LAHDEVIRTA J., MAURY C.P.J., TEPPO A.M. & REPO H. (1988) Elevated levels of circulating cachectin/tumor necrosis factor in patients with acquired immunodeficiency syndrome. Am J Med 85, 289.
12. EMILIE D.M., PEUCHMAUR M.C., MAILLOT M.C. et al. (1990) Production of interleukins in human immunodeficiency virus 1-replicating lymph nodes. J Clin Invest 86, 148.
13. WAHL S.M., ALLEN J.B., GARTNER S. et al (1989) HIV-1 and its envelope glycoprotein down-regulate chemotactic ligand receptors and chemotactic function of peripheral blood monocytes. J Immunol 142, 3553.
14. DÜRRBAUM-LANDMANN I., KALTENHÄUSER E. & ERNST M. (1994) HIV-1 envelope protein gp120 affects phenotype and function of monocytes in vitro. J Leuk Biol 55, 545.
15. + monocytes in patients infected with HTLV-III. Lancet i, 270.
16. MELENDEZ-GUERRERO L.M., NICHOLSON J.K.A. & MCDOUGAL J.S. (1990) In vitro infection of monocytes with HIVBa-L. Effect on cell surface expression of CD4, CD14, HLA-DR, and HLA-DQ. AIDS Res Hum Retroviruses 6, 731.
17. COLLIN M., HERBEIN G., MONTANER L.J. & GORDON S. (1993) PCR analysis of HIV-1 infection of macrophages: virus entry is CD4-dependent. Res Virol 144, 13.
18. LEBON P., POUSOT G., ALCARDI F., GOUTIERES F. & ARTHUIS M. (1979) Early intrathecal synthesis of interferon in herpes encephalitis. Biomedicine 31, 267.
19. TEPPLER H., LEE S.H., RIEBER E.P. & GORDON S. (1990) Murine immunoglobulin G antiCD4 monoclonal antibodies bind to primary human monocytes and macrophages through Fc receptors as well as authentic CD4. AIDS 4, 627.
20. HERBEIN G., DOYLE A.G., MONTANER L.J & GORDON S. (1995) Lipopolysaccharide down-regulates CD4 expression in primary human macrophages through induction of endogenous tumor necrosis factor and interleukin-1β. Clin Exp Immunol 102, 430.
21. FAN J., BASS H.Z. & FAHEY J.L. (1993) Elevated IFN-γ and decreased IL-2 gene expression are associated with HIV infection. J Immunol 151, 5031.
22. MONTANER L.J., GRIFFIN P. & GORDON S. (1994) Interleukin-10 inhibits initial reverse transcription of HIV-1 and mediates a virostatic latent state in primary blood-derived human macrophages. J Gen Virol 75, 3393.
23. AMEGLIO F., CAPOBIANCHI M.R., CASTILLETTI C. et al. (1994) Recombinant gp120 induces IL-10 in resting peripheral blood mononuclear cells; correlation with the induction of other cytokines. Clin Exp Immunol 95, 455.
24. KAZAZI F., MATHIJS J.M., FOLEY P. & CUNNINGHAM A.L. (1989) Variations in CD4 expression by human monocytes and macrophages and their relationship to infection with the human immunodeficiency virus. J Gen Virol 70, 2661.
25. CLAPHAM P.R., WEISS R.A., DALGLEISH A.G., EXLEY M., WHITBY D. & HOGG N. (1987) Human immunodeficiency virus infection of monocytic and T-lymphocytic cells: receptor modulation and differentiation induced by phorbol ester. Virology 158, 44.
26. ANKEL H., CAPOBIANCHI M.R., CASTILLETTI C. & DIANZANI F. (1994) Interferon induction by HIV glycoprotein 120: role of the V3 loop. Virology 205, 34.
27. EYESTER M.E., GOEDERT J., POON M.C. & PREBLE O.T. (1983) Acid-labile alpha interferon. A possible preclinical marker of the acquired immunodeficiency syndrome in hemophilia. N Engl J Med 309, 583.
28. ROUX-LOMBARD P., MODOUX C., CRUSHAUD A. & DAYER G.M. (1989) Purified blood monocytes from HIV-1-infected patients produce high levels of TNF alpha and IL-1. Clin Immunol Immunopathol 50, 374.
29. MARIANI R. & SKOWRONSKI J. (1993) CD4 down-regulation by nef alleles isolated from human immunodeficiency virus type 1-infected individuals. Proc Natl Acad Sci USA 90, 5549.
30. LENBURG M.E. & LANDAU N.R. (1993) Vpu-induced degradation of CD4: requirement for specific amino acid residues in the cytoplasmic domain of CD4. J Virol 61, 7238.