Conditioned fear and analgesia to conspecific odors: Benzodiazepine and 5-HT1A agonists

Psychobiology

Volumn 24, Issue 2, 1996, Pages 118-126

  Hotsenpiller, Gregory ^a   Williams, Jon L ^a  

^a KENYON COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZODIAZEPINE RECEPTOR STIMULATING AGENT; BUSPIRONE; DIAZEPAM; SEROTONIN 1A AGONIST;

ANALGESIA; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CONDITIONING; CONTROLLED STUDY; DRUG EFFECT; FEAR; FREEZING; MALE; NONHUMAN; ODOR; RAT; SMELLING;

EID: 0029886706     PISSN: 08896313     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. ADELL, A., GARCIA-MARQUEZ, C., ARMARIO, A., & GELPI, E. (1988). Chronic stress increases serotonin and noradrenaline in rat brain and sensitizes their responses to a further acute stress. Journal of Neurochemistry, 50, 1678-1681.
2. 1A agonists buspirone and gepirone. Pharmacology, Biochemistry & Behavior, 31 ,269-278.
3. CHOPIN, P., & BRILEY, M. (1987). Animal models of anxiety: The effect of compounds that modify 5-HT neurotransmission. Trends in Pharmacological Sciences, 8, 383-388.
4. COSTALL, B., KELLY, M. E., NAYLOR, R. J., & ONAIVI, E. S. (1988). Actions of buspirone in a putative model of anxiety in the mouse. Journal of Pharmacy & Pharmacology, 40, 494-500.
5. DRUGAN, R. C., CRAWLEY, J. N., PAUL, S. M., & SKOLNICK, P. (1987). Buspirone attenuates learned helplessness behavior in rats. Drug Development Research, 10, 63-67.
6. DRUGAN, R. C., RYAN, S. M., MINOR, T. R., & MAIER, S. F. ( 1984). Librium prevents the analgesia and shuttle box escape deficit typically observed following inescapable shock. Pharmacology, Biochemistry & Behavior, 21, 749-754.
7. EISON, A. S., & TEMPLE, D. L. (1986). Buspirone: Review of its pharmacology and current perspectives on its mechanism of action. American Journal of Medicine, 80(Suppl. 3B), 1-9.
8. FANSELOW, M. S. (1984). Shock-induced analgesia on the formalin test: Effects of shock severity, naloxone, hypophysectomy, and associative variables. Behavioral Neuroscience, 98, 79-95.
9. FANSELOW, M. S., & BAACKES, M. P. (1982). Conditioned fear-induced opiate analgesia on the formalin test: Evidence for two aversive motivational systems. Learning & Motivation, 13, 200-221.
10. FANSELOW, M. S., & HELMSTETTER, F. J. (1988). Conditioned analgesia, defensive freezing, and benzodiazepines. Behavioral Neuroscience, 102, 233-243.
11. FANSELOW, M. S., SIGMUNDI, R. A., & WILLIAMS, J. L. (1987). Response selection and the hierarchical organization of speciesspecific defense reactions: The relationship between freezing, flight, and defensive burying. Psychological Record, 37, 381-386.
12. 1A receptor agonists on the conditioned defensive burying paradigm. In P. Bevan, A. R. Cools, & T. Archer (Eds.), The behavioral pharmacology of 5-HT(pp. 387-392). Hillsdale, NJ: Erlbaum.
13. GLASER, T., RATH, M., TRABER, J., ZILLES, K., & SCHLEICHER, A. (1985). Autoradiographic identification and topographical analyses of high affinity serotonin receptor subtypes as a target for the novel putative anxiolytic TVX Q 7821. Brain Research, 358, 129-136.
14. GRAEFF, F. G., & SILVEIRA FILHO, N. G. (1978). Behavioral inhibition induced by electrical stimulation of the median raphe nucleus of the rat. Pharmacology, Biochemistry & Behavior, 31, 269-278.
15. JACKSON, R. L., MAIER, S. F., & COON, D. J. (1979). Long-term analgesic effects of inescapable shock and learned helplessness. Science, 206, 91-93.
16. KIM, J. J., DECOLA, J. P., LANDEIRA-FERNANDEZ, J., & FANSELOW, M. S. (1991). N-Methyl-D-Aspartate receptor antagonist APV blocks acquisition but not expression of fear conditioning. Behavioral Neuroscience, 105,126-133.
17. MOSER, C. G., & TAIT, R. W. (1983). Environmental control of multiple defensive responses in the conditioned burying paradigm. Journal of Comparative Psychology, 97, 338-352.
18. 3H]-5-hydroxytryptamine. Neuroscience, 6,115-138.
19. PINEL, J. P. J., & MANA, M. J. (1989). Adaptive interactions of rats with dangerous inanimate objects: Support for a cognitive theory of defensive behavior. In R. J. Blanchard, P. F. Brain, D. C. Blanchard, & S. Parmigiani (Eds.), Ethoexperimental approaches to the study of behavior (pp. 137-150). Dordecht: Kluwer.
20. PINEL, J. P. J., & TREIT, D. (1978). Burying as a defensive response in rats. Journal of Comparative & Physiological Psychology, 92,708-712.
21. PIRET, B., DEPAULIS, A., & VERGNES, M. (1991). Opposite effects of agonist and inverse agonist ligands of benzodiazepine receptor on self-defensive and submissive postures in the rat. Psychopharmacology, 103, 56-61.
22. RODGERS, R. I., & RANDALL, J. I. (1987a). Are the analgesic effects of social defeat mediated by benzodiazepine receptors? Physiology & Behavior, 41, 279-289.
23. RODGERS, R. J., & RANDALL, J. I. (1987b). Benzodiazepine ligands, nociception and "defeat" analgesia in male mice. Psychopharmacology, 91, 305-315.
24. RODGERS, R. J., & RANDALL, J. I. (1988a). Blockade of non-opioid analgesia in intruder mice by selective neuronal and non-neuronal benzodiazepine recognition site ligands. Psychopharmacology, 96, 45-54.
25. RODGERS, R. J., & RANDALL, J. I. (1988b). Potent inhibition of nonopioid defeat analgesia in male mice by benzodiazepine antagonist Rol5-3505. Physiology & Behavior, 42, 461-464.
26. 1A agonist, 8-hydroxy-2-(D-n-propylamino)tetralin (8-OH-DPAT), inhibits nonopioid analgesia in defeated mice: Influence of route of administration. Psychopharmacology, 97, 163-165.
27. 1A anxiolytics, buspirone, gepirone and ipsapirone. Psychopharmacology, 99, 374-380.
28. SHEPHARD, R. A. (1987). Behavioral effects of GABA agonists in relation to anxiety and benzodiazepine action. Life Sciences, 40, 2429-2436.
29. SHORT, K. R., & MAIER, S. F. (1991). Localization of a benzodiazepine receptor mediated, control-dependent increase in anxiety following stress in the rat. Society for Neuroscience Abstracts, 37, 283.
30. TAYLOR, D. P., EISON, M. S., RIBLET, L. A., & VANDERMAELEN, C. P. (1985). Pharmacological and clinical effects of buspirone. Pharmacology, Biochemistry & Behavior, 23, 687-694.
31. 1A receptor-related anxiolytics. Trends in Pharmacological Sciences, 8, 432-437.
32. 3 antagonists and benzodiazepines: Their comparative behavioral pharmacology (pp. 107-131). New York: Wiley.
33. TREIT, D., & FUNDYTUS, M. (1988). A comparison of buspirone and chlordiazepoxide in the shock-probe/burying test for anxiolytics. Pharmacology, Biochemistry & Behavior, 30, 1071-1075.
34. TREIT, D., PINEL, J. P. J., & FIBIGER, H. C. (1981). Conditioned defensive burying: A new paradigm for the study of anxiolytic agents. Pharmacology, Biochemistry & Behavior, 15, 619-626.
35. TREIT, D., ROBINSON, A., ROTZINGER, S., & PESOLD, C. (1993). Anxiolytic effects of serotonergic interventions in the shock-probe burying test and the elevated plus-maze test. Behavioral Brain Research, 54, 23-34.
36. WALLETSCHECK, H., & RAAB, A. (1982). Spontaneous activity of dorsal raphe neurons during defensive and offensive encounters in the tree shrew. Physiology & Behavior, 28, 697-705.
37. WESTBROOK, R. F., GREELEY, J. D., NABKE, C. P., & SWINBOURNE, A. L. (1991). Aversive conditioning in the rat: Effects of a benzodiazepine and of an opioid agonist and antagonist on conditioned hypoalgesia and fear. Journal of Experimental Psychology: Animal Behavior Processes, 17, 219-230.
38. WILLIAMS, J. L. (1982). Influence of shock controllability by dominant rats on subsequent attack and defensive behaviors toward colony intruders. Animal Learning & Behavior, 10, 305-313.
39. WILLIAMS, J. L., & GROUX, M. L. (1993). Exposure to various Stressors alters preferences for natural odors in rats (rattus norvegicus). Journal of Comparative Psychology, 107, 39-47.
40. WILLIAMS, J. L., JUST, J. M., & WORLAND, P. D. (1994). Effect of repeateddefeat sessions as a colony intruder on subsequent hypoalgesia and feeding in the rat. Learning & Motivation, 25, 152-174.
41. WILLIAMS, J. L., ROGERS, A. G., & ADLER, A. P. (1990). Prolonged exposure to conspecific and predator odors reduces fear reactions to these odors during subsequent prod-shock tests. Animal Learning & Behavior,18, 453-461.
42. WILLIAMS, J. L., & SCOTT, D. S. (1989). Influence of conspecific and predatory Stressors and their associated odors on defensive burying and freezing responses. Animal Learning & Behavior, 17, 383-393.
43. WILLIAMS, J. L., WORLAND, P. D., & SMITH, M. G. (1990). Defeat-induced hypoalgesia in the rat: Effects of conditioned odors, naltrexone, and extinction. Journal of Experimental Psychology: Animal Behavior Processes, 16, 345-357.