Late induction of CREB/ATF binding and a concomitant increase in cAMP levels in T and B lymphocytes stimulated via the antigen receptor

Journal of Immunology

Volumn 156, Issue 12, 1996, Pages 4582-4593

  Feuerstein, Nili ^a   Firestein, Ron ^a   Aiyar, Nambi ^b   He, Xiao ^a   Murasko, Donna ^a   Cristofalo, Vincent ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; LIPOPOLYSACCHARIDE; LYMPHOCYTE ANTIGEN RECEPTOR; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CELL SPECIFICITY; CELL STIMULATION; COMPLEX FORMATION; DNA SYNTHESIS; ENHANCER REGION; GENE CONTROL; GENE EXPRESSION; GENE INDUCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; T LYMPHOCYTE; TRANSACTIVATION; TRANSCRIPTION REGULATION;

ACTIVATING TRANSCRIPTION FACTORS; ANIMALS; B-LYMPHOCYTES; BASE SEQUENCE; BINDING SITES; BLOOD PROTEINS; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; INTERLEUKIN-2; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED DBA; MOLECULAR SEQUENCE DATA; OLIGODEOXYRIBONUCLEOTIDES; POLYENES; PROLIFERATING CELL NUCLEAR ANTIGEN; PROMOTER REGIONS (GENETICS); RECEPTORS, ANTIGEN, B-CELL; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; SIROLIMUS; T-LYMPHOCYTES; TIME FACTORS; TRANSCRIPTION FACTORS;

EID: 0029886597     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (63)

1. Brindle, P. K., and M. R. Montminy. 1992. The CREB family of transcription activators. Curr. Opin. Genet. Dev. 2:199.
2. Meyer, T. E., and J. F. Habener. 1993. Cyclic 3′,5′-monophosphate response element binding protein (CREB) and related transcription-activating deoxyribo-nucleic acid binding proteins. Endocr. Rev. 14:269.
3. Hai, T., F. Liu, W. J. Coukos, and M. R. Green. 1989. Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA binding heterodimers. Genes Dev. 3:2083.
4. Liu, F., and M. R. Green. 1990. A specific member of the ATF transcription factor family can mediate transcription activation by the adenovims E1a protein. Cell 61:1217.
5. Liu, F., and M. R. Green. 1994. Promoter targeting by adenovirus E1a through interaction with different cellular DNA binding domains. Nature 368:520.
6. Abdel-Hafiz, H. A. M., C.-Y. Chen, T. Marcell, D. J. Kroll, and J. P. Hoeffler. 1993. Structural determinants outside the leucine zipper influence the interaction of CREB and ATF2: interaction of CREB with ATF2 blocks E1a-ATF2 complex formation. Oncogene. 8:1161.
7. Kim, S.-J., S. Wagner, F. Liu. M. A. O'Relly, P. D. Robbins, and M. R. Green. 1992. Retinoblastoma gene product activates expression of the human TGF-β2 gene through transcription factor ATF2. Nature 358:331.
8. Du, W., D. Thanos, and T. Maniatis. 1993. Mechanisms of transcriptional synergism between distinct virus inducible enhancer elements. Cell 74:887.
9. Benbrook, D. M., and N. C. Jones. 1990. Heterodimer formation between CREB and Jun proteins. Oncogene 5:295.
10. Livingstone, C., G. Patel, and N. Jones. 1995. ATF2 contains a phosphorylation-dependent transcriptional activation domain. EMBO J. 14:1785.
11. Gupta, S., D. Cambell, B. Derijard, and R. J. Davis. 1995. Transcription factor ATF2 regulation by the JNK signal transduction pathway. Science. 267:389.
12. Anderson, S. J., S. Miyake, and D. Y. Loh. 1989. Transcription from a murine T cell receptor Vβ promoter depends on a conserved decamer motif similar to the cAMP response element. Mol. Cell. Biol. 9:4835.
13. Lee, M.-R., C.-H. Chung, M.-L. Liou, W.-F. Li, Y.-P. Hsueh, and M.-Z. Lai. 1992. Isolation and characterization of nuclear proteins that bind to T cell receptor Vβ decamer motif. J. Immunol. 148:1906.
14. Georgopoulos, K., B. A. Morgan, and D. D. Moore. 1992. Functionally distinct isoforms of the CRE-BP DNA binding protein mediate activity of a T cell specific enhancer. Mol. Cel. Biol. 12:747.
15. Ho, I.-C., L. H. Yang, G. Morle, and J. M. Leiden. 1989. A T cell specific transcriptional enhancer elements 3′ of Cα in the human T cell receptor α locus. Proc. Natl. Acad. Sci. USA. 86:6714.
16. Gao, M.-H., and P. B. Kavathas. 1993. Functional importance of the cAMP response element-like decamer motif in the CD8α promoter. J. Immunol. 150: 4376.
17. Zhao, L. J., and C. Z. Giam. 1992. Human T cell lymphotropic virus type I (HTLV-1) transcriptional activator, Tax, enhances CREB binding to HILV-1 21-base pair repeat by protein interactions. Proc. Natl. Acad. Sci. USA 89:7070.
18. Franklin, A. A., M. Kubik, M. N. Uttenbogaard, A. Brauweiler, P. Utaisincharoen, M.-A. Matthews, W. S. Dynan, P. J. Hoeffler, and J. K. Nyborg. 1993. Transactivation by the human T cell leukemia virus Tax protein is mediated through enhanced binding of activating transcription factor-2 (ATF2) ATF2 response and cAMP element binding protein (CREB). J. Biol. Chem. 268:21225.
19. Xu, X., D. A. Brown, I. Kitajiama, J. Bilakovics, L. W. Fey, and M. Nerenberg. 1994. Transcriptional suppression of the human T-cell leukemia virus type I long terminal repeat occurs by an unconventional interaction of a CREB factor with the R region. Mol. Cell. Biol. 14:5371.
20. Adam, E., P. Kerkhofs, M. Mammerickx, R. Kettmann, A. Burny, L. Droogmans, and L. Willems. 1994. Involvement of the cyclic AMP responsive element binding protein in bovine leukemia virus expression in vivo. J. Virol. 68:5845.
21. Feuerstein, N., D. Huang, S. H. Hinrichs, D. J. Orten, N. Aiyar, and M. B. Prystowsky. 1995. Regulation of CRE-binding proteins during cell cycle progression of T lymphocytes stimulated with IL-2. J. Immunol. 154:68.
22. Feuerstein, N., D. Huang, and M. B. Prystowsky. 1995. Rapamycin selectively blocks IL-2 induced PCNA gene expression in T lymphocytes: evidence for inhibition of CREB/ATF binding activities. J. Biol. Chem. 270:9454.
23. Morris, G. F., and M. B. Mathews. 1990. Analysis of the proliferating cell nuclear antigen promoter and its response to adenovirus early region 1. J. Biol. Chem. 265:16116.
24. Morris, G. F., and M. B. Mathews. 1991. The adenovirus E1A transforming protein activates the proliferating cell nuclear antigen promoter via an activating transcription factor site. J. Virol. 65:6397.
25. Huang, D., P. M. Shipman-Appasamy, D. J. Orten, S. H. Hinrich, and M. B. Prystowsky. 1994. Promoter activity of the proliferating cell nuclear antigen gene is associated with inducible CRE binding proteins in imerleukin 2-stimulated T lymphocytes. Mol. Cell Biol. 14:4233.
26. Brunswick, M., F. D. Finkelman, P. F. Highet, J. K. Inman, H. M. Dintzis, and J. J. Mond. 1988. Picogram quantities of anti-Ig antibodies coupled to dextran induce B cell proliferation. J. Immunol. 140:3364.
27. Orten, D., J. M. Strawhecker, S. D. Sanderson, D. Huang, M. B. Prystowsky, and S. H. Hinrichs. 1994. Differential effects of monoclonal antibodies on activating transcription factor-1 and cAMP responsive element binding protein interaction with DNA. J. Biol. Chem. 269:32254.
28. Coligan, J. E., A. M. Kruisbeek, D. H. Margulies, E. M. Shevach, and W. Strober. 1995. Current Protocols in Immunology. Wiley Interscience, New York.
29. Feuerstein, N., M. L. Lindsberg, L. Tung, M. L. Francis, and J. J. Mond. 1991. Identification of a prominent 85kDa cAMP-dependent phosphorylation associated with late G1 phase in mitogen stimulated B lymphocytes. J. Biol. Chem. 266:4746.
30. Aiyar, N., E. Griffin, C. Albrightson-Winslow, G. Feuerstein, and P. Nambi. 1992. Homologous desensitization of calcitonin gene related peptides response in rat glomerular mesangial cells in culture. J. Mol. Cell. Biochem. 113:17.
31. Feuerstein, N., and J. J. Mond. 1987. Identification of a prominent nuclear protein associated with proliferation of normal and malignant B cells. J. Immunol. 139: 1818.
32. Feuerstein, R., X. Wang, D. C. Song, N. E. Cooke, and S. A. Liebhaber. 1994. The LIM/double zinc-finger motif as a protein dimerization motif. Proc. Natl Acad Sci. USA 91:10655.
33. Feuerstein, N., and J. I. Mond. 1987. Numatrin, a nuclear matrix protein associated with induction of proliferation in B lymphocytes. J. Biol. Chem. 262: 11389.
34. Montminy, M. R., K. A. Sevarino, J. A. Wagner, G. Mandel, and R. H. Goodman. 1986. Identification of a cyclic AMP responsive element within the rat somatostatin gene. Proc. Natl. Acad. Sci. USA 83:6682.
35. Muller, M. M., S. Ruppert, W. Schaffener, and P. Matthias. 1988. A cloned octamer transcription factor stimulates transcription from lymphoid-specific promoters in non-B cells. Nature 336:544.
36. Dunmont, F. J., J. M. Staruch, S. L. Koprak, M. R. Melino, and N. H. Sigal. 1990. Distinct mechanisms of suppression of murine T cell activation by the related macrolides FK506 and rapamycin. J. Immunol. 144:251.
37. Du, W., and T. Maniatis. 1992. An ATF/CREB binding site protein is required for virus induction of the human interferon β gene. Proc. Natl. Acad. Sci. USA 89:2150.
38. Montminy, M. R., and L. M. Bilezikjian. 1987. Binding of a nuclear protein to the cyclic AMP responsive element of the somatostatin gene. Nature 328:175.
39. Yamamoto, K . K., G. A. Gonzalez, W. G. Briggs, and M. R. Montminy. 1988. Phosphorylation induced binding and transcriptional efficacy of nuclear factor CREB. Nature 334:494.
40. Gonzalez, G. A., and M. R. Montminy. 1989. Cyclic AMP stimulates somatostatin gene transcription by phosphorylation CREB at serine 133. Cell 59:675.
41. Albert, A. S., J. Arias, M. Hagiwara, M. Montminy, and J. R. Feramisco. 1994. Expression of a peptide inhibitor of protein phosphatase 1 increases phosphorylation and activity of CREB in NIH 3T3 fibroblasts. J. Biol. Chem. 269:7623.
42. Hagiwara, M., P. Brindle, A. Harootunian, R. Armstrong, J. Rivier, W. Vale, R. Tsien, and M. R. Montminy. 1993. Coupling of hormonal stimulation and transcriptional activation via cyclic AMP-responsive factor CREB is rate limited by nuclear entry of protein kinase A. Mol Cell. Biol. 13:4852.
43. Chrivia, J. C., R. P. Kwok, N. Lamb, M. Hagiwara, M. R. Montminy, and R. H. Goodman. 1993. Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature 365:855.
44. Arias, J., A. S. Albert, P. Brindle, F. X. Claret, T. Smeal, M. Karin, J. Feramisco, and M. Montminy. 1994. Activation of cAMP and mitogen responsive genes relies on a common nuclear factor. Nature 370:226.
45. Parker, C. W. 1979. Role of cyclic nucleotides in regulating lymphocytes. Ann. NY Acad Sci. 332:255.
46. Kammer, G. M. 1988. The adenylate cyclase-protein kinase A pathway and regulation of the immune response. Immunol. Today 9:222.
47. Haraguchi, S., R. A. Good, and N. K. Day. 1995. Immunosuppressive retroviral peptides: cAMP and cytokine patterns. Immunol. Today 16:595.
48. Koh, W. S., K.-H. Yang, and N. E. Kaminski. 1995. Cyclic AMP is an essential factor in immune responses. Biochim. Biophys. Res. Commun. 206:703.
49. Chakkalath, H. R., and L. K. L. Jung. 1992. Augmentation of phorbol ester induced T cell proliferation by agents which raise intracellular cyclic adenosine monophosphate. Cell. Immunol. 145:240.
50. Li, Y. S., E. Kouassi, and J.-P. Revillard. 1989. cAMP can enhance mouse B cell activation by regulation progression into late G1/S phase. Eur. J. Immunol. 19: 1721.
51. Cohen, D. P., and T. L. Rothstein. 1989. Adenosine 3′,5′-monophosphate modulates the mitogenic responses of murine B lymphocytes. Cell. Immunol. 121: 113.
52. Anastassiou, E. D., H. Yamada, D. Boumpas, G. C. Tsokos, G. Thyphronitis, J. Balow, and J. J. Mond. 1992. Cholera toxin promotes the proliferation of anti-μ antibody-prestimulated human B cells. Cell. Immunol. 140:237.
53. Pollok, K., E., V. O. O'Brien, L. Marshall, J. W. Olson, R. J. Noelle, and E. C. Snow. 1991. The development of competence in resting B cells: the induction of cAMP and ornithine decarboxylase activity after direct contact between B and T helper cells. J. Immunol. 146:1663.
54. Wang, T., J. R. Sheppard, and J. E. Foker. 1978. Rise and fall of cAMP required for onset of lymphocyte DNA synthesis. Science 201:155.
55. Takigawa, M., and B. H. Waksman. 1981. Mechanisms of lymphocyte "depletion" by high concentrations of ligand: cyclic AMP levels and cell death in T lymphocytes exposed to high concentrations of Concanavalin A. Cell. Immunol. 58:29.
56. Xie, H., T. C. Chiles, T. L. Rothstein. 1993. Induction of CREB activity via the surface Ig receptor of B cells. J. Immunol. 151:880.
57. Xie, H., and T. L. Rothstein. 1995. Protein kinase C mediates activation of nuclear cAMP response element binding protein (CREB) in B lymphocytes stimulated through surface Ig. J. Immunol. 154:1717.
58. Novak, T. J., and E. V. Rothenberg. 1990. cAMP inhibits induction of IL-2 but not of interleukin 4 in T cells. Proc. Natl. Acad. Sci. USA 87:9357.
59. Platzer, C., C. Meisel, K. Vogt, M. Platzer, and H. D. Volk. 1995. Up-regulation of monocytic IL-10 by tumor necrosis factor-alpha and cAMP elevating drugs. Int. Immunol. 7:517.
60. Wollberg, W., H. Soderqvist, and D. B. Nelson. 1994. Mitogen activation of human peripheral T lymphocytes induces the formation of new cyclic AMP response element binding protein nuclear complexes. J. Biol. Chem. 269:19719.
61. Su, B., E. Jacinto, M. Hibi, T. Kallunki, M. Karin, and Y. Ben-Neriah. 1994. JNK is involved in signal integration during costimulation of T lymphocytes. Cell 77:727.
62. Lin, Y.-C., and J. Stavnezer. 1992. Regulation of transcription of the germ-line Igα constant region gene by an ATF element and by novel transforming growth factor-β1-responsive elements. J. Immunol. 149:2914.
63. Yin, M.-J., E. J. Paulssen, J.-S. Seeler, and R. B. Gaynor. 1995. Protein domains involved in both in vitro and in vivo interactions between human T-cell leukemia virus type I Tax and CREB. J. Virol. 69:3420.