Mild hypoxia induces hypertrophy of cultured neonatal rat cardiomyocytes: A possible endogenous endothelin-1-mediated mechanism

Journal of Molecular and Cellular Cardiology

Volumn 28, Issue 6, 1996, Pages 1271-1277

  Ito, Hiroshi ^a   Adachi, Susumu ^a   Tamamori, Mimi ^a   Fujisaki, Hiroyuki ^a   Tanaka, Masato ^a   Lin, Meihong ^a   Akimoto, Hajime ^a   Marumo, Fumiaki ^a   Hiroe, Michiaki ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Cardiomyocytes; Endothelin 1; Hypertrophy; Hypoxia; Skeletal actin

Indexed keywords

ALPHA ACTIN; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN 1; ENDOTHELIN A RECEPTOR ANTAGONIST; LEUCINE; MESSENGER RNA; PROTEIN PRECURSOR; TRITIUM;

ANIMAL CELL; ARTICLE; CELL DEATH; CONTROLLED STUDY; GENE INDUCTION; HEART HYPERTROPHY; HEART MUSCLE CELL; HYPOXIA; IMAGE ANALYSIS; ISOTOPE LABELING; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; RAT;

EID: 0029886594     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1996.0117     Document Type: Article

References (22)

1. ANVERSA P, LOUD AV, LEVICKY V, GUIDERI G, 1985. Left ventricular failure induced by myocardial infarction. I. Myocyte hypertrophy. Am J Physiol 17: H876-H882.
2. CHOMCZYNSKI P, SACCHI N, 1987. Single-step method of RNA isolation by acid quanidinium thiocyanatephenol-chloroform extraction. Anal Biochem 162: 156-160.
3. FEINBERG AP, VOGELSTEIN BA, 1983. Technique for radio-labeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 132: 6-13.
4. FUJISAKI H, ITO H, HIRATA Y, TANAKA M, HATA M, LIN M, ADACHI S, AKIMOTO H, MARUMO F, HIROE M, 1985. Natriuretic peptides inhibit angiotensin II-induced proliferation of rat cardiac fibroblasts by blocking endothelin-1 gene expression. J Clin Invest 96: 1059-1065.
5. GINZTON LE, CONANT R, RODRIGUES DC, LAKS MM, 1989. Functional significance of hypertrophy of the non-infarcted myocardium after myocardial infarction in humans. Circulation 80: 816-822.
6. HOCKSMAN JS, BULKELY BH, 1983. Pathogenesis of left ventrilar aneurysms: an experimental study in the rat model. Am J Cardiol 50: 83-88.
7. A receptor. Life Sciences 50: 247-255.
8. ITO H, HIRATA Y, HIROE M, TSUJINO M, ADACHI S, TAKAMOTO T, NITTA M, TANIGUCHI K, MARUMO F, 1991. Endothelin-1 induces hypertrophy with enhanced expression of muscle-specific genes in cultured neonatal rat cardiomyocytes. Circ Res 69: 209-215.
9. ITO H, HIRATA Y, ADACHI S, TANAKA M, TSUJINO M, KOIKE A, NOGAMI A, MARUMO F, HIROE M, 1993a. Ehdothelin-1 is an autocrine/paracrine factor in the mechanism of angiotensis II-induced hypertrophy in cultures rat cardiomyocytes. J Clin Invest 92: 398-403.
10. ITO H, HIROE M, HIRATA Y, TSUJINO M, ADACHI S, SHICHIRI M, KOIKE A, NOGAMI A, MARUMO F, 1993b. Insulin-like growth factor-I induces hypertrophy with enhanced expression of muscle specific genes in cultured rat cardiomyocytes. Circulation 87: 1715-1721.
11. ITO H, MILLER SC, BILLINGHAM ME, AKIMOTO H, TORTI S, WADE R, GAHLMANN R, LYONS G, KEDES L, TORTI FM, 1990. Doxorubicin selectively inhibits muscle gene expression in cardiac muscle cells in vitro and in vivo. Proc Natl Acad Sci USA 87: 4275-4279.
12. NIINIKOSKI J, HUNT TK, DUNPHY JE, 1972. Oxygen supply in healing tissue. Am J Surg 123: 247-252.
13. OLIVETTI G, RICCI R, BEHI C, GUIDERI G, ANVERSA P, 1986. Response of the border zone to myocardial infarction in rats. Am J Pathol 125: 476-483.
14. PANTELY GA, BRISTOW JD, 1984. Ischemic cardiomyopathy. Prog Cardiovasc Diseases 27: 95-114.
15. REBERTS CS, MACLEAN D, BRAUNWALD E, MAROKO PR, KLONER RA, 1983. Topographic changes in the left ventricle after experimentally induced myocardial infarction in the rat. Am J Cardiol 51: 872-876.
16. SHUBEITA HE, MCDONOUGH PM, HARRIS AN, KNOWLTON KU, GLEMBOTSKI CC, BROWN JH, CHIEN KR, 1990. Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes. Aparacrine mechanism for myocardial cell hypertrophy. J Biol Chem 265: 20555-20562.
17. SILVERSTEIN JL, STEEN VD, MEDSGER JR TA, FALANGAM V, 1988. Cutaneus hypoxia in patients with systemic sclerosis (scleroderma). Arch Dermatol 124: 1379-1382.
18. SIMPSON P, SAVION S, 1982. Differentiation of rat myocytes in single cell cultures with and without proliferation nonmyocardial cells. Circ Res 50: 101-116.
19. SUZUKI T, HOSHI H, MITSUI Y, 1990. Endothelin stimulates hypertrophy and contractility of neonatal rat cardiac myocytes in a serum-free medium. FEBS Lett 268: 149-151.
20. TANAKA M, ITO H, ADACHI S, AKIMOTO H, NISHIKAWA T, KASAJIMA T, MARUMO F, HIROE M, 1994. Hypoxia induces apoptosis with enhanced expression of Fas antigen mRNA in cultured neonatal rat cardiomyocytes. Circ Res 75: 426-433.
21. WEBSTER KA, DISCHER DJ, BISHOPRIC NH, 1993. Induction and nuclear accumulation of Fos and Jun proto-oncogenes in hypoxic cardiac myocytes. J Biol Chem 268: 16852-16858.
22. YANAGISAWA M, KURIHARA H, KIMURA S, TOMOBE Y, KOBAYASHI M, MITSUI Y, YAZAKI Y, GOTO K, MASAKI T, 1988. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 332: 411-415.