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Volumn 20, Issue 6, 1996, Pages 553-560

The use of discordant sibling pairs for finding genetic loci linked to obesity: Practical considerations

Author keywords

Body mass index; Discordant sibling pairs; Genetic epidemiology; Genetic linkage; Obesity; Statistical power

Indexed keywords

ARTICLE; BODY FAT; BODY MASS; BODY WEIGHT; GENE LOCUS; GENETIC EPIDEMIOLOGY; GENETIC LINKAGE; HUMAN; OBESITY; PHENOTYPE; PRIORITY JOURNAL; SIBLING;

EID: 0029886586     PISSN: 03070565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (33)

References (54)
  • 4
    • 0025740249 scopus 로고
    • Current understanding of the etiology of obesity: Genetic and nongenetic factors
    • Bouchard C. Current understanding of the etiology of obesity: genetic and nongenetic factors. Am J Clin Nutr 1991; 53: 1561S-1565S.
    • (1991) Am J Clin Nutr , vol.53
    • Bouchard, C.1
  • 5
    • 0029113623 scopus 로고
    • Genetics of obesity: An update on molecular markers
    • Bouchard C. Genetics of obesity: an update on molecular markers. Int J Obesity 1995; 19: Suppl. 3, S10-S13.
    • (1995) Int J Obesity , vol.19 , Issue.3 SUPPL.
    • Bouchard, C.1
  • 6
    • 0029157769 scopus 로고
    • Human obesity does not segregate with the chromosomal regions of Prader-Willi, Bardet-Biedl, Cohen, Borjeson or Wilson-Turner syndromes
    • Reed DR, Ding Y, Cather C, Price R. Human obesity does not segregate with the chromosomal regions of Prader-Willi, Bardet-Biedl, Cohen, Borjeson or Wilson-Turner syndromes. Int J Obesity 1995; 19(9): 599-603.
    • (1995) Int J Obesity , vol.19 , Issue.9 , pp. 599-603
    • Reed, D.R.1    Ding, Y.2    Cather, C.3    Price, R.4
  • 7
    • 0029401938 scopus 로고
    • Absence of linkage between human obesity and the mouse agouti homologous region (20q11.2) or other markers spanning chromosome 20q
    • Xu W, Reed DR, Ding Y, Price A. Absence of linkage between human obesity and the mouse agouti homologous region (20q11.2) or other markers spanning chromosome 20q. Obes Res 1995; 3: 559-562.
    • (1995) Obes Res , vol.3 , pp. 559-562
    • Xu, W.1    Reed, D.R.2    Ding, Y.3    Price, A.4
  • 8
    • 0026270312 scopus 로고
    • Of needles and haystacks: Finding human disease genes by positional cloning
    • Collins FS. Of needles and haystacks: finding human disease genes by positional cloning. Clin Res 1991; 39(4): 615-623.
    • (1991) Clin Res , vol.39 , Issue.4 , pp. 615-623
    • Collins, F.S.1
  • 10
    • 0028090414 scopus 로고
    • Genetic dissection of complex traits
    • Lander ES, Schork NJ. Genetic dissection of complex traits. Science 1994; 265: 2037-2048.
    • (1994) Science , vol.265 , pp. 2037-2048
    • Lander, E.S.1    Schork, N.J.2
  • 11
    • 0028116099 scopus 로고
    • Disease susceptibility genes and the sib-pair method: A review of recent methodology
    • Shah S, Green JR. Disease susceptibility genes and the sib-pair method: a review of recent methodology. Ann Human Genet 1994; 58: 381-395.
    • (1994) Ann Human Genet , vol.58 , pp. 381-395
    • Shah, S.1    Green, J.R.2
  • 12
    • 0027173803 scopus 로고
    • Path analysis and sib-pair linkage
    • Carey G, Williamson JA. Path analysis and sib-pair linkage. Genet Epidem 1993; 10: 103-112.
    • (1993) Genet Epidem , vol.10 , pp. 103-112
    • Carey, G.1    Williamson, J.A.2
  • 13
    • 0020640573 scopus 로고
    • Linkage between a marker locus and a quantitative trait of sibs
    • Cockerman CC, Weir BS. Linkage between a marker locus and a quantitative trait of sibs. Am J Human Genet 1983; 35: 263-273.
    • (1983) Am J Human Genet , vol.35 , pp. 263-273
    • Cockerman, C.C.1    Weir, B.S.2
  • 14
    • 0027171992 scopus 로고
    • Improved sib-pair linkage test for disease susceptibility loci
    • Faraway JJ. Improved sib-pair linkage test for disease susceptibility loci. Genet Epidem 1993; 10: 225-233.
    • (1993) Genet Epidem , vol.10 , pp. 225-233
    • Faraway, J.J.1
  • 15
    • 0015309467 scopus 로고
    • The investigation of linkage between a quantitative trait and a marker locus
    • Haseman JK, Elston RC. The investigation of linkage between a quantitative trait and a marker locus. Behav Genet 1972; 2: 3-19.
    • (1972) Behav Genet , vol.2 , pp. 3-19
    • Haseman, J.K.1    Elston, R.C.2
  • 16
    • 0029007702 scopus 로고
    • Proportion of genome shared identical by descent by relatives concept, computation and applications
    • Guo S. Proportion of genome shared identical by descent by relatives concept, computation and applications. Am J Human Genet 1995; 56: 1468-1476.
    • (1995) Am J Human Genet , vol.56 , pp. 1468-1476
    • Guo, S.1
  • 17
    • 0021957675 scopus 로고
    • A comparison of sib-pair linkage tests for disease susceptibility loci
    • Blackwelder WC, Elston RC. A comparison of sib-pair linkage tests for disease susceptibility loci. Genet Epidem 1985; 2: 85-97.
    • (1985) Genet Epidem , vol.2 , pp. 85-97
    • Blackwelder, W.C.1    Elston, R.C.2
  • 18
    • 0027756035 scopus 로고
    • Statistical validity of the Haseman-Elston sib-pair test in small samples
    • Wilson AF, Elston RC. Statistical validity of the Haseman-Elston sib-pair test in small samples. Genet Epidem 1993; 10: 593-598.
    • (1993) Genet Epidem , vol.10 , pp. 593-598
    • Wilson, A.F.1    Elston, R.C.2
  • 19
    • 0027440662 scopus 로고
    • Two-locus models of disease: Comparison of likelihood and nonparametric linkage methods
    • Goldin LR, Weeks DE. Two-locus models of disease: comparison of likelihood and nonparametric linkage methods. Am J Human Genet 1993; 53: 908-915.
    • (1993) Am J Human Genet , vol.53 , pp. 908-915
    • Goldin, L.R.1    Weeks, D.E.2
  • 20
    • 0026600683 scopus 로고
    • Comparison of multipoint identity-by-descent method with parametric multipoint linkage analysis for mapping quantitative traits
    • Goldgar DE, Oniki Rebecca S. Comparison of multipoint identity-by-descent method with parametric multipoint linkage analysis for mapping quantitative traits. Am J Human Genet 1992; 50: 598-606.
    • (1992) Am J Human Genet , vol.50 , pp. 598-606
    • Goldgar, D.E.1    Oniki Rebecca, S.2
  • 21
    • 0028071382 scopus 로고
    • The power of interval mapping of quantitative trait loci, using selected sib pairs
    • Cardon LR, Fulker DW. The power of interval mapping of quantitative trait loci, using selected sib pairs. Am J Human Genet 1994; 55: 825-833.
    • (1994) Am J Human Genet , vol.55 , pp. 825-833
    • Cardon, L.R.1    Fulker, D.W.2
  • 22
    • 0028947057 scopus 로고
    • Multipoint interval mapping of quantitative trait loci, using sib pair
    • Fulker DW, Cherny SS, Cardon LR. Multipoint interval mapping of quantitative trait loci, using sib pair. Am J Human Genet 1995; 56: 1224-1233.
    • (1995) Am J Human Genet , vol.56 , pp. 1224-1233
    • Fulker, D.W.1    Cherny, S.S.2    Cardon, L.R.3
  • 23
    • 0029001682 scopus 로고
    • Extreme discordant sib pairs for mapping quantitative trait loci in humans
    • Risch N, Zhang H. Extreme discordant sib pairs for mapping quantitative trait loci in humans. Science 1995; 268: 1584-1589.
    • (1995) Science , vol.268 , pp. 1584-1589
    • Risch, N.1    Zhang, H.2
  • 24
    • 0028102233 scopus 로고    scopus 로고
    • Locating human quantitative trait loci: Guidelines for the selection of sibling pairs for genotyping
    • Eaves L, Meyer J. Locating human quantitative trait loci: guidelines for the selection of sibling pairs for genotyping. Behav Genet 24(5): 443-455.
    • Behav Genet , vol.24 , Issue.5 , pp. 443-455
    • Eaves, L.1    Meyer, J.2
  • 26
    • 0000130974 scopus 로고
    • The use of extreme groups to test for the presence of a relationship
    • Feldt LS. The use of extreme groups to test for the presence of a relationship. Psychometrika 1961; 26: 307-316.
    • (1961) Psychometrika , vol.26 , pp. 307-316
    • Feldt, L.S.1
  • 27
    • 0001259076 scopus 로고
    • The use of extreme groups in assessing relationships
    • Alf EF, Abrahams NM. The use of extreme groups in assessing relationships. Psychometrika 1975; 40: 563-572.
    • (1975) Psychometrika , vol.40 , pp. 563-572
    • Alf, E.F.1    Abrahams, N.M.2
  • 28
    • 0008725784 scopus 로고
    • Relative costs and statistical power in the extreme groups approach
    • Abrahams NM, Alf EF. Relative costs and statistical power in the extreme groups approach. Psychometrika 1978; 4: 11-17.
    • (1978) Psychometrika , vol.4 , pp. 11-17
    • Abrahams, N.M.1    Alf, E.F.2
  • 29
    • 84976918844 scopus 로고
    • Using the extreme groups strategy when measures are not normally distributed
    • Fowler RL. Using the extreme groups strategy when measures are not normally distributed. Appl Psychol Measurement 1992; 16: 249-259.
    • (1992) Appl Psychol Measurement , vol.16 , pp. 249-259
    • Fowler, R.L.1
  • 30
    • 0026629701 scopus 로고
    • Strategies for characterizing highly polymorphic markers in human gene mapping
    • Ott J. Strategies for characterizing highly polymorphic markers in human gene mapping. Am J Human Genet 1992; 51: 283-290.
    • (1992) Am J Human Genet , vol.51 , pp. 283-290
    • Ott, J.1
  • 31
    • 0005865141 scopus 로고
    • Genetics of obesity: Family studies
    • C Bouchard (ed.). CRC Press: Boca Raton, FL, chap. 6
    • Bouchard C, Perusse L. Genetics of obesity: family studies. In: C Bouchard (ed.). Genetics of obesity. CRC Press: Boca Raton, FL, 1994, chap. 6, pp 79-92.
    • (1994) Genetics of Obesity , pp. 79-92
    • Bouchard, C.1    Perusse, L.2
  • 32
    • 0039721823 scopus 로고
    • The Ohio State University: Columbus, OH
    • Center for Human Resource Research. NLS Handbook. The Ohio State University: Columbus, OH, 1995.
    • (1995) NLS Handbook
  • 36
    • 0025916226 scopus 로고
    • Non-paternity and prenatal genetic screening
    • Macintyre S, Sooman Anne. Non-paternity and prenatal genetic screening. Lancet 1991; 338: 869-871.
    • (1991) Lancet , vol.338 , pp. 869-871
    • Macintyre, S.1    Anne, S.2
  • 37
    • 0028062086 scopus 로고
    • Estimating the frequency of nonpaternity in Switzerland
    • Sasse G, Muller H, Chakraborty R, Ott J. Estimating the frequency of nonpaternity in Switzerland. Human Hered 1994; 44: 337-343.
    • (1994) Human Hered , vol.44 , pp. 337-343
    • Sasse, G.1    Muller, H.2    Chakraborty, R.3    Ott, J.4
  • 39
  • 40
    • 0001278937 scopus 로고
    • Genetic studies of obesity across the life span
    • JR Turner, LR Cardon, JK Hewitt (eds). Plenum Press: New York, Chapter 8
    • Meyer JM. Genetic studies of obesity across the life span. In: Behavior genetics approaches in behavioral medicine, JR Turner, LR Cardon, JK Hewitt (eds). Plenum Press: New York, 1995, Chapter 8, pp 145-166.
    • (1995) Behavior Genetics Approaches in Behavioral Medicine , pp. 145-166
    • Meyer, J.M.1
  • 41
    • 0026251539 scopus 로고
    • The nature of environmental influences on weight and obesity: A behavior genetic analysis
    • Grilo CM, Pogue-Geile MF. The nature of environmental influences on weight and obesity: a behavior genetic analysis. Psychol Bull 1991; 110: 520-537.
    • (1991) Psychol Bull , vol.110 , pp. 520-537
    • Grilo, C.M.1    Pogue-Geile, M.F.2
  • 46
    • 0003864799 scopus 로고
    • US Department of Health and Human Services. Centers for Disease Control and Prevention: Hyattsville, MD
    • US Department of Health and Human Services. National Health Interview Survey. US Department of Health and Human Services. Centers for Disease Control and Prevention: Hyattsville, MD, 1991.
    • (1991) National Health Interview Survey
  • 48
  • 49
    • 0023975511 scopus 로고
    • Inter-generation transmission of physical fitness in the Canadian population
    • Perusse L, Leblance C, Bouchard C. Inter-generation transmission of physical fitness in the Canadian population. Can J Sport Sci 1988; 13: 8.
    • (1988) Can J Sport Sci , vol.13 , pp. 8
    • Perusse, L.1    Leblance, C.2    Bouchard, C.3
  • 51
    • 84995262687 scopus 로고
    • Genetic and environmental contributions to the variance of the body mass index in a Norwegian sample of first- And second-degree relatives
    • Tambs K, Moum T, Eaves L, Neale M, Midthjell K, Lund-Larsen PG, Naess S, Holmen J. Genetic and environmental contributions to the variance of the body mass index in a Norwegian sample of first- and second-degree relatives. Am J Human Biol 1991; 3: 257.
    • (1991) Am J Human Biol , vol.3 , pp. 257
    • Tambs, K.1    Moum, T.2    Eaves, L.3    Neale, M.4    Midthjell, K.5    Lund-Larsen, P.G.6    Naess, S.7    Holmen, J.8
  • 52
    • 0343694270 scopus 로고
    • Observations showing that a white woman, by intercourse with a white man and a Negro man, may conceive twins, one of which shall be white and the other mulatto
    • Hexadae 1
    • Archer J. Observations showing that a white woman, by intercourse with a white man and a Negro man, may conceive twins, one of which shall be white and the other mulatto. Medical Repository, 3d, Hexadae 1, 1810; 319.
    • (1810) Medical Repository, 3d , pp. 319
    • Archer, J.1
  • 53
    • 0028472439 scopus 로고
    • A genetic analysis of weight residualized for height among 4020 twin pairs with an emphasis on sex specific effects
    • Allison DB, Heshka S, Neale MC, Lykken DT, Heymsfield SB. A genetic analysis of weight residualized for height among 4020 twin pairs with an emphasis on sex specific effects. Health Psychol 1994; 13: 362-365.
    • (1994) Health Psychol , vol.13 , pp. 362-365
    • Allison, D.B.1    Heshka, S.2    Neale, M.C.3    Lykken, D.T.4    Heymsfield, S.B.5
  • 54
    • 0026830656 scopus 로고
    • Changes in sibling configurations in American preschool children
    • Eggebeen DJ. Changes in sibling configurations in American preschool children. Social Biol 1992; 39: 27-44.
    • (1992) Social Biol , vol.39 , pp. 27-44
    • Eggebeen, D.J.1


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