Comparative analysis of the expression patterns of metalloproteinases and their inhibitors in breast neoplasia, sporadic colorectal neoplasia, pulmonary carcinomas and malignant non-Hodgkin's lymphomas in humans

British Journal of Cancer

Volumn 73, Issue 11, 1996, Pages 1401-1408

  Kossakowska, A E ^a,c   Huchcroft, S A ^b   Urbanski, S J ^a   Edwards, D R ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b Alberta Cancer Board   (Canada)

^c FOOTHILLS HOSPITAL   (Canada)

Author keywords

Breast neoplasia; Extracellular matrix; Metalloproteinases; Tissue inhibitors of metalloproteinases

Indexed keywords

GELATINASE; MESSENGER RNA; METALLOPROTEINASE; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE;

ARTICLE; BREAST CARCINOMA; CARCINOGENICITY; CARCINOMA IN SITU; CLINICAL ARTICLE; COLON CARCINOMA; COMPARATIVE STUDY; GENE EXPRESSION; HUMAN; HUMAN TISSUE; LUNG CARCINOMA; NONHODGKIN LYMPHOMA; NORTHERN BLOTTING; PRIORITY JOURNAL;

ADENOFIBROMA; BREAST; BREAST DISEASES; BREAST NEOPLASMS; COLORECTAL NEOPLASMS; FEMALE; FIBROCYSTIC BREAST DISEASE; GELATINASES; GLYCOPROTEINS; HUMANS; LUNG NEOPLASMS; LYMPHOMA, NON-HODGKIN; MATRIX METALLOPROTEINASE 11; METALLOENDOPEPTIDASES; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; PREDICTIVE VALUE OF TESTS; PROTEIN BIOSYNTHESIS; PROTEINS; RNA, MESSENGER; SENSITIVITY AND SPECIFICITY; TISSUE INHIBITOR OF METALLOPROTEINASE-2; TISSUE INHIBITOR OF METALLOPROTEINASES; TRANSCRIPTION, GENETIC; TUMOR MARKERS, BIOLOGICAL;

EID: 0029886352     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1996.266     Document Type: Review

References (58)

1. ALBINI A, MELCHIORI A, SANTI L, LIOTTA LA, BROWN PD AND STETLER-STEVENSON WG. (1991). Tumour cell invasion inhibited by TIMP-2. J. Natl Cancer Inst., 83, 775-779.
2. ALEXANDER CM AND WERB Z. (1991). Extracellular matrix degradation. In Cell Biology of Extracellular Matrix. Hay ED, (ed.) pp. 255-302. Plenum Press: New York.
3. AZZAM HS, ARAND G, LIPPMAN ME AND THOMPSON EW. (1993). Association of MMP-2 activation potential with metastatic progression in human breast cancer cell lines independent of MMP-2 production. J. Natl Cancer Inst., 85, 1758-1765..
4. BASSET P, BELLOCQ JP, WOLF C, STOLL I, HUTIN P, LIMACHER JM, PODHAJCER OL, CHENARD MP, RIO MC AND CHAMBON P. (1990). A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas. Nature, 348, 699-704.
5. BASSET P, WOLF C, ROUYER N, BELLOCQ J-P, RIO M-C AND CHAMBON P. (1994). Stromelysin-3 in stromal tissue as a control factor in breast cancer behavior. Cancer. 74, 1045-1049.
6. BEHRENDTSEN O, ALEXANDER CM AND WERB Z. (1992). Metalloproteinases mediate extracellular matrix degradation by cells from mouse blastocyst outgrowths. Development, 114, 447-456.
7. BERNHARD EJ, GRUBER SB AND MUSCHEL RJ. (1992). Direct evidence linking expression of matrix metalloproteinase-9 (92-kDa gelatinase/collagenase) to the metastatic phenotype in transformed rat embryo cells. Proc. Natl Acad. Sci. USA, 91, 4293-4297.
8. BERTAUX B, HORNEBECK W, EISEN AZ AND DUBERTRET L. (1991). Growth stimulation of human keratinocytes by tissue inhibitor of metalloproteinases. J. Invest. Derm., 97, 679-685.
9. CHOMCZYNSKI P AND SACCHI N. (1987). Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162, 156-159.
10. CLAVEL C, POLETTE M, DOCO M, BINNINGER I AND BIREMBAUT P. (1992). Immunolocalization of matrix metalloproteinases and their tissue inhibitor in human mammary pathology. Bull. Cancer, 79, 261-270.
11. COLLIER IE, WILHELM SM, EISEN AZ, MARMER BL, GRANT GA, SELTZER JL, KRONBERGER A, HE C, BAUER EA AND GOLDBERG GI. (1988). H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloproteinase capable of degrading basement membrane collage. J. Biol. Chem., 263, 6579-6587.
12. DAVIES B, WAXMAN J, WASAN H, ABEL P, WILLIAMS G, KRAUSZ T, NEAL D, THOMAS D, HANBY A AND BALKWILL F. (1993). Levels of matrix metalloproteinases in bladder cancer correlate with tumour grade and invasion. Cancer Res., 53, 5365-5369.
13. DECLERCK YA, YEAN T-D, CHAN D, SHIMADA H AND LANGLEY KE. (1991). Inhibition of tumour invasion of smooth muscle cell layers by recombinant human metalloproteinase inhibitor. Cancer Res., 51, 2151-2157.
14. DECLERCK YA, PEREZ N, SHIMADA H, BOONE TC, LANGLEY KE AND TAYLOR SM. (1992). Inhibition of invasion and metastasis in cells transfected with an inhibitor of metalloproteinases. Cancer Res., 52, 701-708.
15. r 72,000 type IV collagenase. Cancer Res., 52, 5845-5848.
16. GRAY ST, YUN K, MOTOORI T AND KUYS YM. (1993). Interstitial collagenase gene expression in colonie neoplasia. Am. J. Pathol., 143, 663-671.
17. HAYAKAWA T, YAMASHITA K, UCHIJIMA E AND IWATA K. (1992). Growth-promoting activity of tissue inhibitor of metalloproteinases-1 (TIMP-1) for a wide range of cells. FEBS Lett, 289, 29-32.
18. HEMBRY RM, MURPHY G, CAWSTON TE, DINGLE JT AND REYNOLDS JJ. (1986). Characterization of a specific antiserum for mammalian collagenase from several species: immunolocalization of collagenase in rabbit chondrocytes and uterus. J. Cell Sci., 81, 105-123.
19. JUAREZ J, CLAYMAN G, NAKAJIMA M, TANABE KK, SAYA H, NICOLSON GL AND BOYD D. (1993). Role and regulation of expression of 92-kDa type-IV collagenase (MMP-9) in 2 invasive squamous-cell-carcinoma cell lines of the oral cavity. Int. J. Cancer, 55, 10-18.
20. KHOKHA R, WATERHOUSE P, YAGEL S, LALA PK, OVERALL CM, NORTON G AND DENHARDT DT. (1989). Antisense RNA-induced reduction in murine TIMP levels confers oncogenicity on Swiss 3T3 cells. Science, 243, 947-950.
21. KHOKHA R, ZIMMER MJ, GRAHAM CH, LALA PK AND WATERHOUSE P. (1992). Suppression of invasion by inducible expression of tissue inhibitor of metalloproteinase-1 (TIMP-1) inB16-F10 melanoma cells. J. Natl Cancer Inst., 84, 1017-1023.
22. KLEINER DE JR AND STETLER-STEVENSON WG. (1993). Structural biochemistry and activation of matrix metalloproteinases. Cell Biol., 5, 891-897.
23. KORCZAK B, KERBEL RS AND DENNIS JW. (1991). Autocrine and paracrine regulation of tissue inhibitor of metalloproteinases, transin, and urokinase gene expression in metastatic and nonmetastatic mammary carcinoma cells. Cell Growth Differ., 2, 335-341.
24. KOSSAKOWSKA AE, URBANSKI SJ AND EDWARDS DR. (1991). Tissue inhibitor of metalloproteinases-1 (TIMP-1) RNA is expressed at elevated levels in malignant non-Hodgkin's lymphomas. Blood, 77, 2475-2481.
25. KOSSAKOWSKA AE, URBANSKI SJ, HUCHCROFT SA AND EDWARDS DR. (1992). Relationship between the clinical aggressiveness of large cell immunoblastic lymphomas and expression of 92kDa gelatinase (type IV collagenase) and tissue inhibitors of metalloproteinases-1 (TIMP-1) RNAs. Oncol. Res., 4, 223-240.
26. KOSSAKOWSKA AE, URBANSKI SJ, WATSON A, HAYDEN LJ AND EDWARDS DR. (1993). Patterns of expression of metalloproteinases and their inhibitors in human malignant lymphomas. Oncol. Res., 5, 19-28.
27. LECO KJ, HAYDEN LJ, SHARMA RR, ROCHELEAU H, GREENBERG AH AND EDWARDS DR. (1992). Differential regulation of TIMP-1 and TIMP-2 mRNA expression in normal and Ha-ras-transformed murine fibroblasts. Gene, 117, 209-217.
28. LIBRACH CL, WERB Z, FITZGERALD ML, CHIU K, CORWIN NM, ESTEVES RA, GROBELNY D, GALARDY R, DAMSKY CH AND FISHER SJ. (1991). 92-kD type IV collagenase mediates invasion of human cytotrophoblasts. J. Cell Biol., 113, 437-449.
29. LIOTTA LA, STEEG PS AND STETLER-STEVENSON WG. (1991). Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation. Cell, 64, 327-336.
30. MIGNATTI P AND RIFKIN DB. (1993). Biology and biochemistry of proteinases in tumour invasion. Physiol. Rev., 73, 161-195.
31. MIGNATTI P, ROBBINS E AND RIFKIN DB. (1986). Tumour invasion through the human amniotic membrane: requirement for a proteinase cascade. Cell. 47, 486-498.
32. MONSKY WL, KELLY T, LIN C-Y, YEH Y, STETLER-STEVENSON WG, MUELLER SC AND CHEN W-T. (1993). Binding and localization of MT 72,000 matrix metalloproteinase at cell surface invadopodia. Cancer Res., 53, 3159-3164.
33. MONTEAGUDO C, MERINO MJ, SAN-JUAN J, LIOTTA LA AND STETLER-STEVENSON WG. (1990). Immunohistochemical distribution of type IV collagenase in normal, benign, and malignant breast tissue. Ann. J. Pathol., 136, 585-592.
34. MULLER D, WOLF C, ABECASSIS J, MILLON R, ENGELMANN A, BRONNER G, ROUYER N, RIO M-C, EBER M, METHLIN G, CHAMBON P AND BASSET P. (1993). Increased stromelysin 3 gene expression is associated with increased local invasiveness in head and neck squamous cell carcinomas. Cancer Res., 53, 165-169.
35. MURPHY AN, UNSWORTH EJ AND STETLER-STEVENSON WG. (1993). Tissue inhibitor of metalloproteinases-2 inhibits bFGF-induced human microvascular endothelial cell proliferation. J. Cell. Physiol., 157, 351-358.
36. MURPHY G, SEGAIN J-P, O'SHEA M, COCKETT M, IOANNOU C, LEFEBVRE O, CHAMBON P AND BASSET P. (1993). The 28-kDa N-terminal domain of mouse stromelysin-3 has the general properties of a weak metalloproteinase. J. Biol. Chem., 268, 15435-15441.
37. NAKAJIMA M, WELCH DR, BELLONI PN AND NICOLSON GL. (1987). Degradation of basement membrane type IV collagen and lung subendothelial matrix by rat mammary adenocarcinoma cell clones of differing metastatic potentials. Cancer Res., 47, 4869-4876.
38. NEMETH JA AND GOOLSBY CL. (1993). TIMP-2, a growth-stimulatory protein from SV40-transformed human fibroblasts. Exp. Cell. Res., 207, 376-382.
39. NORUSIS MJ. (1988). SPSS/PC + V2.0 Base Manual. SPSS Inc: Chicago.
40. PEI D, MAJMUDAR G AND WEISS SJ. (1944). Hydrolytic inactivation of a breast carcinoma cell-derived serpin by human stromelysin-3. J. Biol. Chem., 269, 25849-25855.
41. POLETTE M, GILBERT N, STAS I, NAWROCKI B, NOEL A, REMACLE A. STETLER-STEVENSON WG, BIREMAUT P AND FOIDART J-M. (1994). Gelatinase A expression and localization in human breast cancers. An in situ hybridization study and immunohistochemical detection using confocal microscopy. Virchows Archiv., 424, 641-645.
42. POULSOM R, HANBY AM, PIGNATELLI M, JEFFERY RE, LONGCROFT JM, ROGERS L AND STAMP GWH. (1993). Expression of gelatinase A and TIMP-2 mRNAs in desmoplastic fibroblasts in both mammary carcinomas and basal cell carcinomas of the skin. J. Clin. Pathol., 46, 429-436.
43. RIMM A, HARTZ AJ, KALBFLEISCH JH, ANDERSON AJ AND HOFFMANN RG. (1980). Basic Biostatistics in Medicine and Epidemiology, pp. 56-58. Appleton Century Crofts: New York.
44. SAMBROOK J, FRITSCH EF AND MANIATIS T. (1989). Molecular Cloning: a Laboratory Manual, 2nd edn. Cold Spring Harbor Laboratory Press: New York.
45. SATO H, TAKINO T, OKADA Y, CAO J, SHINAGAWA A, YAMAMOTO E AND SEIKI M. (1994). A matrix metalloproteinase expressed on the surface of invasive tumour cells. Nature, 370, 61-65.
46. SOINI Y, HURSKAINEN T, HOYHTYA M, OIKARINEN A AND AUTIO-HARMAINEN H. (1994). 72 kD and 92 kD type IV collagenase, type IV collagen and laminin mRNAs in breast cancer: a study by in situ hybridization. J. Histochem. Cytochem., 42, 945-951.
47. STETLER-STEVENSON WG, BROWN PD, ONISTO M, LEVY AT AND LIOTTA LA. (1990). Tissue inhibitor of metalloproteinases-2 (TIMP-2) mRNA expression in tumour cell lines and human tumour tissue. J. Biol. Chem., 265, 13933-13938.
48. STETLER-STEVENSON WG, AZNAVOORIAN S AND LIOTTA LA. (1993). Tumour cell interactions with the extracellular matrix during invasion and metastasis. Cell Biol., 9, 541-573.
49. URBANSKI SJ, EDWARDS DR, MAITLAND A, LECO KJ, WATSON A AND KOSSAKOWSKA AE. (1992). Expression of metalloproteinases and their inhibitors in primary pulmonary carcinomas. Br. J. Cancer, 66, 1188-1194.
50. URBANSKI SJ, EDWARDS DR, HERSHFIELD N, HUCHCROFT SA, SHAFHER E, SUTHERLAND L AND KOSSAKOWSKA AE. (1993). Expression pattern of metalloproteinases and their inhibitors changes with the progression of human sporadic colorectal neoplasia. Diag. Mol. Path., 2, 81-89.
51. VASSALLI J-D AND PEPPER MS. (1994). Membrane proteases in focus. Nature, 370, 14.
52. WAGNER SN, RUHRI C, KUNTH K, HOLECEK BU, GOOS M, HOFLER H AND ATKINSON MJ. (1992). Expression of stromelysin 3 in the stromal elements of human basal cell carcinoma. Diagn. Molec. Pathol., 1, 200-205.
53. WATANABE H, NAKANISHI I, YAMASHITA K, HAYAKAWA T AND OKADA Y. (1993). Matrix metalloproteinase-9 (92 kDa gelatinase/type IV collagenase) from U937 monoblastoid cells: correlation with cellular invasion. J. Cell. Sci., 104, 991-999.
54. WHITELOCK JM, PAINE ML, GIBBINS JR, KEFFORD RF AND O'GRADY RL. (1993). Multiple levels of post-transcriptional regulation of collagenase (matrix metalloproteinase 1) in an epithelial cell line. Immunol. Cell Biol., 71, 39-47.
55. WILHELM SM, COLLIER IE, MARMER BL, EISEN AZ, GRANT GA AND GOLDBERG GI. (1989). SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophages. J. Biol. Chem., 264, 17213-17221.
56. WOLF C, ROUYER N, LUTZ Y, ADIDA C, LORIOT M, BELLOCQ J-P, CHAMBON P AND BASSET P. (1993). Stromelysin 3 belongs to a subgroup of proteinases expressed in breast carcinoma fibroblastic cells and possibly implicated in tumour progression. Proc. Natl Acad. Sci. USA, 90, 1843-1847.
57. XIE B, BUCANA CD AND FIDLER IJ. (1994). Density-dependent induction of 92-kd type IV collagenase activity in cultures of A431 human epidermoid carcinoma cells. Am. J. Pathol., 144, 1058-1067.
58. r 92,000 type IV collagenase is increased in plasma of patients with colon cancer and breast cancer. Cancer Res., 53, 140-146.