Specificity of DNA alkylation by 1-(2-chloroethyl)-3-alkyl-3-acyltriazenes depends on the structure of the acyl group: Kinetic and product studies

Chemical Research in Toxicology

Volumn 9, Issue 2, 1996, Pages 466-475

  Kroeger Smith, Marilyn B ^a   Schmidt, Brigitte F ^a   Czerwinski, Grzegorz ^a   Taneyhill, Lisa A ^b   Snyder, Emily J ^b   Kline, Adam M ^b   Michejda, Christopher J ^a   Smith Jr , Richard H ^a,b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b WESTERN MARYLAND COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SUIDAE;

1 (2 CHLOROETHYL)TRIAZENE DERIVATIVE; 7 METHYLGUANINE; ALKANE; ALKYLATING AGENT; CARBOXYLIC ACID; DIAZONIUM COMPOUND; DNA; ESTERASE; PHOSPHATE; TRIAZENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DEACYLATION; DNA ADDUCT; DNA ALKYLATION; DRUG DECOMPOSITION; DRUG DNA INTERACTION; DRUG HYDROLYSIS; DRUG STRUCTURE; DRUG SYNTHESIS; KINETICS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE;

ALKYLATING AGENTS; ALKYLATION; ANIMALS; CATTLE; DNA; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; THYMUS GLAND; TRIAZENES;

EID: 0029885998     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx950155y     Document Type: Article

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