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Volumn 14, Issue 2, 1996, Pages 85-92

Ethics of clinical trials

Author keywords

clinical trial; ethics; randomization

Indexed keywords

CLINICAL PRACTICE; CLINICAL TRIAL; DOCTOR PATIENT RELATION; HUMAN; HUMAN EXPERIMENT; INFORMED CONSENT; MEDICAL ETHICS; PATIENT REFERRAL; PATIENT SELECTION; PRIORITY JOURNAL; RANDOMIZATION; REVIEW;

EID: 0029885932     PISSN: 07348630     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-1016315     Document Type: Review
Times cited : (11)

References (53)
  • 1
    • 0023613644 scopus 로고
    • The ethics of randomized clinical trials
    • Roser F: The ethics of randomized clinical trials. Am J Med 82:283-290, 1987
    • (1987) Am J Med , vol.82 , pp. 283-290
    • Roser, F.1
  • 2
    • 0029003913 scopus 로고
    • The ethics of clinical trials
    • Baum M: The ethics of clinical trials. Isr J Med Sci 31:197-200, 1995
    • (1995) Isr J Med Sci , vol.31 , pp. 197-200
    • Baum, M.1
  • 3
    • 0025828348 scopus 로고
    • Clinical trials - Are they ethical?
    • Rassamani E: Clinical trials - are they ethical? N Engl J Med 324:1589-1592, 1991
    • (1991) N Engl J Med , vol.324 , pp. 1589-1592
    • Rassamani, E.1
  • 4
    • 0020486516 scopus 로고
    • Historical controls: The practitioner's clinical trials
    • Lasagna L: Historical controls: The practitioner's clinical trials. N Engl J Med 307:1339-1340, 1982
    • (1982) N Engl J Med , vol.307 , pp. 1339-1340
    • Lasagna, L.1
  • 5
    • 0006372671 scopus 로고
    • The problem of experimentation on human beings. I. the research workers point of view
    • Shimkin MB: The problem of experimentation on human beings. I. The research workers point of view. Science 117:205-207, 1953
    • (1953) Science , vol.117 , pp. 205-207
    • Shimkin, M.B.1
  • 6
    • 0020325090 scopus 로고
    • The ethics of the randomized clinical trial
    • Schafer A: The ethics of the randomized clinical trial. N Engl J Med 307:719-724, 1982
    • (1982) N Engl J Med , vol.307 , pp. 719-724
    • Schafer, A.1
  • 7
    • 0026481374 scopus 로고
    • The substantive ethics of clinical trials
    • Lilford R: The substantive ethics of clinical trials. Clin OB Gynecol 35:837-845, 1992
    • (1992) Clin OB Gynecol , vol.35 , pp. 837-845
    • Lilford, R.1
  • 8
    • 0023185342 scopus 로고
    • Equipoise and the ethics of clinical research
    • Freedman B: Equipoise and the ethics of clinical research. N Engl J Med 317:141-145, 1987
    • (1987) N Engl J Med , vol.317 , pp. 141-145
    • Freedman, B.1
  • 9
    • 0025906439 scopus 로고
    • Of mice but not men
    • Hellman S, Hellman D: Of mice but not men. N Engl J Med 324:1585-1589, 1991
    • (1991) N Engl J Med , vol.324 , pp. 1585-1589
    • Hellman, S.1    Hellman, D.2
  • 10
    • 77951529251 scopus 로고
    • Streptomycin treatment of pulmonary tubercles
    • Medical Research Council: Streptomycin treatment of pulmonary tubercles. Br Med J 2:769-782, 1948
    • (1948) Br Med J , vol.2 , pp. 769-782
  • 11
    • 0028070548 scopus 로고
    • The continuing unethical use of placebo controls
    • Rothman KJ, Michels KB: The continuing unethical use of placebo controls. N Engl J Med 331:394-397, 1994
    • (1994) N Engl J Med , vol.331 , pp. 394-397
    • Rothman, K.J.1    Michels, K.B.2
  • 12
    • 0017304984 scopus 로고
    • The fiction of informed consent
    • Laforet E: The fiction of informed consent. JAMA 235:1579-1585, 1976
    • (1976) JAMA , vol.235 , pp. 1579-1585
    • Laforet, E.1
  • 13
    • 0015516764 scopus 로고
    • Ethical experimentation and the editor
    • Woodford FP: Ethical experimentation and the editor. N Engl J Med 286:892, 1972
    • (1972) N Engl J Med , vol.286 , pp. 892
    • Woodford, F.P.1
  • 16
    • 0002758524 scopus 로고
    • Oath of Hippocrates
    • Reich WT (ed): New York, Simon & Schuster
    • Hippocrates: Oath of Hippocrates. In Reich WT (ed): Encyclopedia of Bioethics. Vol. 5. New York, Simon & Schuster, 1995
    • (1995) Encyclopedia of Bioethics , vol.5
    • Hippocrates1
  • 17
    • 0024963284 scopus 로고
    • AIDS drug trials enter new age
    • Palca J: AIDS drug trials enter new age. Science 246:19-21, 1989
    • (1989) Science , vol.246 , pp. 19-21
    • Palca, J.1
  • 18
    • 0027436807 scopus 로고
    • Informed consent. the whole truth for patients?
    • Lantos J: Informed consent. The whole truth for patients? Cancer 72:2811-2815, 1993
    • (1993) Cancer , vol.72 , pp. 2811-2815
    • Lantos, J.1
  • 20
    • 0020070038 scopus 로고
    • Ethical issues in informed consent. Research on medical cost containment
    • Mahler D, Veatch R, Sidel V: Ethical issues in informed consent. Research on medical cost containment. JAMA 247:481-485, 1982
    • (1982) JAMA , vol.247 , pp. 481-485
    • Mahler, D.1    Veatch, R.2    Sidel, V.3
  • 21
    • 0015355213 scopus 로고
    • Models for ethical medicine in a revolutionary age
    • Veatch RM: Models for ethical medicine in a revolutionary age. Hasting Center Rep 2:5-7, 1972
    • (1972) Hasting Center Rep , vol.2 , pp. 5-7
    • Veatch, R.M.1
  • 22
    • 9344240147 scopus 로고    scopus 로고
    • Salgo v Stanford, 154 Cal App 2d 560; 317 P2d 170 (1957)
    • Salgo v Stanford, 154 Cal App 2d 560; 317 P2d 170 (1957)
  • 24
    • 0017476385 scopus 로고
    • Respect for persons and informed consent to participate in research
    • Lebacqz K, Levine RJ: Respect for persons and informed consent to participate in research. Clin 25:101-107, 1977
    • (1977) Clin , vol.25 , pp. 101-107
    • Lebacqz, K.1    Levine, R.J.2
  • 26
    • 9344263167 scopus 로고
    • 95 Eng Rep 860 (1767)
    • Grundeuner T (ed): On the Readability of Surgical Consent Form
    • Slater V, Baker, Stapleton CB: 95 Eng Rep 860 (1767). In Grundeuner T (ed): On the Readability of Surgical Consent Form. N Engl J Med 302:900-902, 1980
    • (1980) N Engl J Med , vol.302 , pp. 900-902
    • Slater, V.1    Baker2    Stapleton, C.B.3
  • 27
    • 0028243766 scopus 로고
    • The context of consent
    • Horton R: The context of consent. Lancet 344:211-212, 1994
    • (1994) Lancet , vol.344 , pp. 211-212
    • Horton, R.1
  • 28
    • 0028261390 scopus 로고
    • Informed consent: An evaluation of patients' understanding and opinion
    • Sow KC, Wood AM, Murphy K, Parry J, Hartfall WG: Informed consent: An evaluation of patients' understanding and opinion. JR Soc Med 87:143-144, 1994
    • (1994) JR Soc Med , vol.87 , pp. 143-144
    • Sow, K.C.1    Wood, A.M.2    Murphy, K.3    Parry, J.4    Hartfall, W.G.5
  • 30
    • 0014530749 scopus 로고
    • Obtaining informed consent: Form or substance
    • Epstein LC, Lasagna L: Obtaining informed consent: Form or substance. Arch Intern Med 123:682-688, 1969
    • (1969) Arch Intern Med , vol.123 , pp. 682-688
    • Epstein, L.C.1    Lasagna, L.2
  • 31
    • 0017181107 scopus 로고
    • Informed consent: Recall by patients tested post-operatively
    • Robinson G, Merar A: Informed consent: Recall by patients tested post-operatively. Ann Thorac Surg 22:209-212, 1976
    • (1976) Ann Thorac Surg , vol.22 , pp. 209-212
    • Robinson, G.1    Merar, A.2
  • 32
    • 0018776441 scopus 로고
    • Written informed consent in patients with breast cancer
    • Mujs HB, White DR, Michielutte R, et al: Written informed consent in patients with breast cancer. Cander 43:1549-1556, 1979
    • (1979) Cander , vol.43 , pp. 1549-1556
    • Mujs, H.B.1    White, D.R.2    Michielutte, R.3
  • 33
    • 0014004559 scopus 로고
    • Consent in clinical experimentation: Myth and reality
    • Beecher HK: Consent in clinical experimentation: Myth and reality. JAMA 195:124-125, 1966
    • (1966) JAMA , vol.195 , pp. 124-125
    • Beecher, H.K.1
  • 34
    • 84920237602 scopus 로고
    • How informed
    • Anonymous. Consent: How informed. Lancet 1445-1447, 1984
    • (1984) Lancet , pp. 1445-1447
  • 35
    • 0021737751 scopus 로고
    • Randomized clinical trials of cancer treatment - A public opinion survey
    • Kemp N, Skinner E, Toms J: Randomized clinical trials of cancer treatment - a public opinion survey. Clin Oncol 10:155-161, 1984
    • (1984) Clin Oncol , vol.10 , pp. 155-161
    • Kemp, N.1    Skinner, E.2    Toms, J.3
  • 36
    • 0019965584 scopus 로고
    • Attitudes toward clinical trials among patients and the public
    • Cassileth BR, Lusk EJ, Miller DS, Hurwitz S: Attitudes toward clinical trials among patients and the public. JAMA 248:968-970, 1982
    • (1982) JAMA , vol.248 , pp. 968-970
    • Cassileth, B.R.1    Lusk, E.J.2    Miller, D.S.3    Hurwitz, S.4
  • 37
    • 0021339672 scopus 로고
    • Physicians' reasons for not entering eligible patients in a randomized clinical trial of surgery for breast cancer
    • Taylor KM, Margolese RG, Soskolne CL: Physicians' reasons for not entering eligible patients in a randomized clinical trial of surgery for breast cancer. N Engl J Med 310:1363-1367, 1984
    • (1984) N Engl J Med , vol.310 , pp. 1363-1367
    • Taylor, K.M.1    Margolese, R.G.2    Soskolne, C.L.3
  • 39
    • 0024238840 scopus 로고
    • How expert physicians would want to be treated if they had genitourinary cancer
    • Moore MJ, O'Sullivan B, Tannock IF: How expert physicians would want to be treated if they had genitourinary cancer. J Clin Oncol 6:1736-1745, 1988
    • (1988) J Clin Oncol , vol.6 , pp. 1736-1745
    • Moore, M.J.1    O'Sullivan, B.2    Tannock, I.F.3
  • 40
    • 0025346048 scopus 로고
    • Finders fee for research subject
    • Lind S: Finders fee for research subject. N Engl J Med 323:192-195, 1990
    • (1990) N Engl J Med , vol.323 , pp. 192-195
    • Lind, S.1
  • 41
    • 2642678384 scopus 로고
    • American College of Physicians Ethics Manual. Part 1: History, the patient, other physicians
    • American College of Physicians - American College of Physicians Ethics Manual. Part 1: History, the patient, other physicians. Ann Intern Med 111:245-252, 1989
    • (1989) Ann Intern Med , vol.111 , pp. 245-252
  • 43
    • 0023043825 scopus 로고
    • Mammona and medicine: The rewards of clinical trials
    • Spiro HM: Mammona and medicine: The rewards of clinical trials. JAMA 255:1174-1175, 1986
    • (1986) JAMA , vol.255 , pp. 1174-1175
    • Spiro, H.M.1
  • 44
    • 0028849245 scopus 로고
    • Subverting randomization in controlled trials
    • Schulz K: Subverting randomization in controlled trials. JAMA 274:1456-1458, 1995
    • (1995) JAMA , vol.274 , pp. 1456-1458
    • Schulz, K.1
  • 47
    • 0347311350 scopus 로고
    • The randomized clinical trial - For whose benefit?
    • Schafer A: The randomized clinical trial - for whose benefit? FRB: Rev Hum Subj Res 7:4-6, 1985
    • (1985) FRB: Rev Hum Subj Res , vol.7 , pp. 4-6
    • Schafer, A.1
  • 48
    • 0018385004 scopus 로고
    • Terminating a trial-the ethical problem
    • Meier P: Terminating a trial-the ethical problem. Clin Pharmacol Ther 25:633-640, 1979
    • (1979) Clin Pharmacol Ther , vol.25 , pp. 633-640
    • Meier, P.1
  • 49
    • 0016768314 scopus 로고
    • Numerators without denominators
    • Spodick D: Numerators without denominators. JAMA 232:35-36, 1975
    • (1975) JAMA , vol.232 , pp. 35-36
    • Spodick, D.1
  • 50
    • 0001587714 scopus 로고
    • Surgery as a placebo: A quantitative study
    • Beecher N: Surgery as a placebo: A quantitative study. JAMA 176:1102, 1961
    • (1961) JAMA , vol.176 , pp. 1102
    • Beecher, N.1
  • 51
    • 70449243257 scopus 로고
    • An evaluation of internal mammary artery ligation by double-blind technique
    • Cobb LA, Thomas CI, Pillard DN, et al: An evaluation of internal mammary artery ligation by double-blind technique. N Engl J Med 260:1115, 1959
    • (1959) N Engl J Med , vol.260 , pp. 1115
    • Cobb, L.A.1    Thomas, C.I.2    Pillard, D.N.3
  • 52
    • 0016838202 scopus 로고
    • Drugs and operations
    • Love J: Drugs and operations. JAMA 232:37-38, 1975
    • (1975) JAMA , vol.232 , pp. 37-38
    • Love, J.1
  • 53
    • 0018782393 scopus 로고
    • Are randomized trials appropriate for evaluating new operations?
    • Bonchek L: Are randomized trials appropriate for evaluating new operations? N Engl J Med 301:44-45, 1975
    • (1975) N Engl J Med , vol.301 , pp. 44-45
    • Bonchek, L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.