-
1
-
-
0023859179
-
The pharmacology of potassium channels and their therapeutic potential
-
Cook NS. The pharmacology of potassium channels and their therapeutic potential. Trends in Pharmacol Sciences 1988; 9: 21-28.
-
(1988)
Trends in Pharmacol Sciences
, vol.9
, pp. 21-28
-
-
Cook, N.S.1
-
2
-
-
0025814921
-
Mechanisms of vasodilatation induced by potassium channel activators
-
Kajioka S, Nakashima M, Kitamura K, Kuriyama H. Mechanisms of vasodilatation induced by potassium channel activators. Clin Sci 1991; 81; 129-139.
-
(1991)
Clin Sci
, vol.81
, pp. 129-139
-
-
Kajioka, S.1
Nakashima, M.2
Kitamura, K.3
Kuriyama, H.4
-
3
-
-
0023761002
-
Pinacidil actions on ion channels in vascular muscle
-
Hermsmeyer RK. Pinacidil actions on ion channels in vascular muscle. J Cardiovasc Pharmacol 1988; 12 (Suppl 2): 17-22.
-
(1988)
J Cardiovasc Pharmacol
, vol.12
, Issue.2 SUPPL.
, pp. 17-22
-
-
Hermsmeyer, R.K.1
-
4
-
-
0027537286
-
Pharmacodynamic model of the haemodynamic effects of pinacidil in normotensive volunteers
-
Girard P, Saumet JL, Dubois F, Boissel JP. Pharmacodynamic model of the haemodynamic effects of pinacidil in normotensive volunteers. Eur J Clin Pharmacol 1993; 44: 177-182.
-
(1993)
Eur J Clin Pharmacol
, vol.44
, pp. 177-182
-
-
Girard, P.1
Saumet, J.L.2
Dubois, F.3
Boissel, J.P.4
-
5
-
-
0025367478
-
Pinacidil: A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in the treatment of hypertension
-
Friedel AF, Brogden RN. Pinacidil: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in the treatment of hypertension. Drugs 1990; 39: 929-967.
-
(1990)
Drugs
, vol.39
, pp. 929-967
-
-
Friedel, A.F.1
Brogden, R.N.2
-
6
-
-
0026498034
-
Potassium channel openers: Pharmacological and clinical aspects
-
Quast U. Potassium channel openers: pharmacological and clinical aspects. Fundam Clin Pharmacol 1992; 6: 279-293.
-
(1992)
Fundam Clin Pharmacol
, vol.6
, pp. 279-293
-
-
Quast, U.1
-
7
-
-
0026562018
-
Clinical pharmacology of potassium channel openers
-
Andersson KE. Clinical pharmacology of potassium channel openers. Pharmacol Toxicol 1992; 70: 244-254.
-
(1992)
Pharmacol Toxicol
, vol.70
, pp. 244-254
-
-
Andersson, K.E.1
-
8
-
-
0024419724
-
Effects of putative activators of potassium channels in mouse pancreatic B-cells
-
Garrino MG, Plant TD, Henquin JC. Effects of putative activators of potassium channels in mouse pancreatic B-cells. Br J Pharmacol 1989; 98: 957-965.
-
(1989)
Br J Pharmacol
, vol.98
, pp. 957-965
-
-
Garrino, M.G.1
Plant, T.D.2
Henquin, J.C.3
-
10
-
-
0025318574
-
Ion channels and insulin secretion
-
Rajan AS et al. Ion channels and insulin secretion. Diabetes Care 1990; 13: 340-363.
-
(1990)
Diabetes Care
, vol.13
, pp. 340-363
-
-
Rajan, A.S.1
-
11
-
-
0026740141
-
Dual functional role of membrane depolarization/calcium influx in rat pancreatic B-cell
-
Sato Y et al. Dual functional role of membrane depolarization/calcium influx in rat pancreatic B-cell. Diabetes 1992; 41: 438-443.
-
(1992)
Diabetes
, vol.41
, pp. 438-443
-
-
Sato, Y.1
-
12
-
-
0026459938
-
+ channels by chronic glyburide and pinacidil administration
-
+ channels by chronic glyburide and pinacidil administration. Biochem Pharmacol 1992; 44: 1843-1847.
-
(1992)
Biochem Pharmacol
, vol.44
, pp. 1843-1847
-
-
Gopalakrishnan, M.1
Triggle, D.J.2
-
14
-
-
0026021161
-
Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and athersclerotic cardiovascular disease
-
DeFronzo RA, Ferrannini E. Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and athersclerotic cardiovascular disease. Diabetes Care 1991; 14: 173-194.
-
(1991)
Diabetes Care
, vol.14
, pp. 173-194
-
-
DeFronzo, R.A.1
Ferrannini, E.2
-
15
-
-
0026035365
-
Impaired insulin action on skeletal muscle metabolism in essential hypertension
-
Natali A et al. Impaired insulin action on skeletal muscle metabolism in essential hypertension. Hypertension 1991; 17: 170-178.
-
(1991)
Hypertension
, vol.17
, pp. 170-178
-
-
Natali, A.1
-
16
-
-
0025997702
-
The hemodynamic link between insulin resistance and hypertension
-
Julius S et al. The hemodynamic link between insulin resistance and hypertension. J Hypertens 1991; 9: 983-986.
-
(1991)
J Hypertens
, vol.9
, pp. 983-986
-
-
Julius, S.1
-
17
-
-
0028025349
-
Insulin resistance, compensatory hyperinsulinemia, and coronary heart disease
-
Reaven GM, Laws A. Insulin resistance, compensatory hyperinsulinemia, and coronary heart disease. Diabetologia 1994; 37: 948-952.
-
(1994)
Diabetologia
, vol.37
, pp. 948-952
-
-
Reaven, G.M.1
Laws, A.2
-
19
-
-
0028231187
-
The link between insulin resistance and hypertension. Effects of antihypertensive and antihyperlipidemic drugs on insulin sensitivity
-
Baba T, Neugebauer S. The link between insulin resistance and hypertension. Effects of antihypertensive and antihyperlipidemic drugs on insulin sensitivity. Drugs 1994; 47: 383-404.
-
(1994)
Drugs
, vol.47
, pp. 383-404
-
-
Baba, T.1
Neugebauer, S.2
-
20
-
-
0028011912
-
Serum insulin level versus blood pressure: A cross-sectional, case controlled study in non-obese, middle-aged Japanese subjects with normal glucose tolerance
-
Baba T et al. Serum insulin level versus blood pressure: a cross-sectional, case controlled study in non-obese, middle-aged Japanese subjects with normal glucose tolerance. Diabet Med 1994; 11: 42-49.
-
(1994)
Diabet Med
, vol.11
, pp. 42-49
-
-
Baba, T.1
-
21
-
-
0023759937
-
Application of prazosin is associated with an increase of insulin sensitivity in obese patients with hypertension
-
Pollare T, Lithell H, Selinus I, Berne C. Application of prazosin is associated with an increase of insulin sensitivity in obese patients with hypertension. Diabetologia 1988; 31: 415-420.
-
(1988)
Diabetologia
, vol.31
, pp. 415-420
-
-
Pollare, T.1
Lithell, H.2
Selinus, I.3
Berne, C.4
-
22
-
-
0024428292
-
A comparison of the effects of hydrochlorothiazide and captopril on glucose and lipid metabolism in patients with hypertension
-
Pollare T, Lithell H, Berne C. A comparison of the effects of hydrochlorothiazide and captopril on glucose and lipid metabolism in patients with hypertension. N Engl J Med 1989; 321: 868-873.
-
(1989)
N Engl J Med
, vol.321
, pp. 868-873
-
-
Pollare, T.1
Lithell, H.2
Berne, C.3
-
23
-
-
9344238371
-
Potassium channel modulation: Effect of pinacidil and glibenclamide on insulin release in healthy volunteers
-
Thesis. Haren, Niemeijer, The Netherlands
-
Links TP, Smit AJ, Reitsma WD. Potassium channel modulation: effect of pinacidil and glibenclamide on insulin release in healthy volunteers. In: Familial hypokalemic periodic paralysis (Thesis). Haren, Niemeijer, The Netherlands, 1992, pp 123-130.
-
(1992)
Familial Hypokalemic Periodic Paralysis
, pp. 123-130
-
-
Links, T.P.1
Smit, A.J.2
Reitsma, W.D.3
-
24
-
-
0027489335
-
The potassium channel opener pinacidil in hypertension: Effect on glucose tolerance and insulin secretion
-
Ligtenberg JJM et al. The potassium channel opener pinacidil in hypertension: effect on glucose tolerance and insulin secretion. J Drug Dev 1993; 6: 63-68.
-
(1993)
J Drug Dev
, vol.6
, pp. 63-68
-
-
Ligtenberg, J.J.M.1
-
25
-
-
0024205602
-
Reduction of insulin clearance during hyperglycemic clamp. Dose-response study in normal humans
-
Tillil H et al. Reduction of insulin clearance during hyperglycemic clamp. Dose-response study in normal humans. Diabetes 1988; 37: 1351-1357.
-
(1988)
Diabetes
, vol.37
, pp. 1351-1357
-
-
Tillil, H.1
-
26
-
-
0023850277
-
Quantitative study of insulin secretion and clearance in normal and obese subjects
-
Polonsky KS et al. Quantitative study of insulin secretion and clearance in normal and obese subjects. J Clin Invest 1988; 81: 435-441.
-
(1988)
J Clin Invest
, vol.81
, pp. 435-441
-
-
Polonsky, K.S.1
-
27
-
-
0025647505
-
Dose-response characteristics for glucose-stimulated insulin release in man and the assessment of influence of glucose on arginine stimulated insulin release
-
Van Haeften TW et al. Dose-response characteristics for glucose-stimulated insulin release in man and the assessment of influence of glucose on arginine stimulated insulin release. Metabolism 1990; 39: 1292-1299.
-
(1990)
Metabolism
, vol.39
, pp. 1292-1299
-
-
Van Haeften, T.W.1
-
28
-
-
0018520840
-
Glucose clamp technique: A method for quantifying insulin secretion and resistance
-
DeFronzo RA, Tobin JD, Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 1979; 237: E214-E223.
-
(1979)
Am J Physiol
, vol.237
-
-
DeFronzo, R.A.1
Tobin, J.D.2
Andres, R.3
-
29
-
-
0020317517
-
Simple and fast solvent extraction system for selective and quantitative isolation of adrenaline, noradrenaline and dopamine from plasma and urine
-
Smedes F, Kraak JC, Poppe H. Simple and fast solvent extraction system for selective and quantitative isolation of adrenaline, noradrenaline and dopamine from plasma and urine. J Chromatogr 1982; 231: 25-39.
-
(1982)
J Chromatogr
, vol.231
, pp. 25-39
-
-
Smedes, F.1
Kraak, J.C.2
Poppe, H.3
-
30
-
-
0025976627
-
Insulin resistance and compensatory hyperinsulinemia: Role in hypertension, dyslipidemia, and coronary heart disease
-
Reaven GM. Insulin resistance and compensatory hyperinsulinemia: role in hypertension, dyslipidemia, and coronary heart disease. Am Heart J 1991; 121: 1283-1288.
-
(1991)
Am Heart J
, vol.121
, pp. 1283-1288
-
-
Reaven, G.M.1
-
32
-
-
0022575392
-
Cardiovascular effects of pinacidil and propranolol alone and in combination in normal humans
-
Nicholls DP, McNeill J, Harron DW, Shanks RG. Cardiovascular effects of pinacidil and propranolol alone and in combination in normal humans. J Cardiovasc Pharmacol 1986; 8: 51-54.
-
(1986)
J Cardiovasc Pharmacol
, vol.8
, pp. 51-54
-
-
Nicholls, D.P.1
McNeill, J.2
Harron, D.W.3
Shanks, R.G.4
-
33
-
-
0024952787
-
Potassium channel stimulation in normal subjects and in patients with hypertension: An acute study with cromakalim
-
Singer DRJ et al. Potassium channel stimulation in normal subjects and in patients with hypertension: an acute study with cromakalim. J Hypertens 1989; 7: 294-295.
-
(1989)
J Hypertens
, vol.7
, pp. 294-295
-
-
Singer, D.R.J.1
-
34
-
-
0022356260
-
Sulfonylurea therapy doubles B-cell response to glucose in type 2 diabetic patients
-
Hosker JP et al. Sulfonylurea therapy doubles B-cell response to glucose in type 2 diabetic patients. Diabetologia 1985; 28: 809-814.
-
(1985)
Diabetologia
, vol.28
, pp. 809-814
-
-
Hosker, J.P.1
-
35
-
-
0024458172
-
Dose response characteristics for arginine-stimulated insulin secretion in man and influence of hyperglycemia
-
Van Haeften TW, Voetberg GA, Gerich JE, Van der Veen EA. Dose response characteristics for arginine-stimulated insulin secretion in man and influence of hyperglycemia. J Clin Endocrinol Metab 1989; 69: 1059-1064.
-
(1989)
J Clin Endocrinol Metab
, vol.69
, pp. 1059-1064
-
-
Van Haeften, T.W.1
Voetberg, G.A.2
Gerich, J.E.3
Van Der Veen, E.A.4
-
36
-
-
0019222406
-
Mechanism of glucose-induced insulin secretion
-
Hedeskov CJ. Mechanism of glucose-induced insulin secretion. Physiol Rev 1980; 60: 442-509.
-
(1980)
Physiol Rev
, vol.60
, pp. 442-509
-
-
Hedeskov, C.J.1
-
37
-
-
0015324585
-
Decreased sensitivity of the pancreatic beta cells to glucose in prediabetic and diabetic subjects. A glucose dose-response study
-
Cerasi E, Luft R, Efendic S. Decreased sensitivity of the pancreatic beta cells to glucose in prediabetic and diabetic subjects. A glucose dose-response study. Diabetes 1972; 21: 224-234.
-
(1972)
Diabetes
, vol.21
, pp. 224-234
-
-
Cerasi, E.1
Luft, R.2
Efendic, S.3
-
38
-
-
0017836046
-
D-Glucose inhibits potassium efflux from pancreatic island cells
-
Henquin JC. D-Glucose inhibits potassium efflux from pancreatic island cells. Nature 1978; 271: 271-273.
-
(1978)
Nature
, vol.271
, pp. 271-273
-
-
Henquin, J.C.1
-
39
-
-
0022375444
-
Glucose dependent potassium channels in pancreatic B-cells are regulated by intracellular ATP
-
Rorsman R, Trube G. Glucose dependent potassium channels in pancreatic B-cells are regulated by intracellular ATP. Pflugers Arch 1985; 405: 305-309.
-
(1985)
Pflugers Arch
, vol.405
, pp. 305-309
-
-
Rorsman, R.1
Trube, G.2
-
40
-
-
0021741559
-
Glucose induces closure of single potassium channels in isolated rat pancreatic beta-cells
-
Ashcroft FM, Harrison DE, Ashcroft SJ. Glucose induces closure of single potassium channels in isolated rat pancreatic beta-cells. Nature 1984; 312; 446-448.
-
(1984)
Nature
, vol.312
, pp. 446-448
-
-
Ashcroft, F.M.1
Harrison, D.E.2
Ashcroft, S.J.3
-
41
-
-
0022877325
-
Calcium transport in pancreatic B-cells: Implications for glucose regulation of insulin release
-
Hellman B. Calcium transport in pancreatic B-cells: implications for glucose regulation of insulin release. Diabetes/Metab Rev 1986; 2: 215-241.
-
(1986)
Diabetes/Metab Rev
, vol.2
, pp. 215-241
-
-
Hellman, B.1
-
42
-
-
0023525741
-
2+, cAMP, and phospholipid-derived messengers in coupling mechanisms of insulin secretion
-
2+, cAMP, and phospholipid-derived messengers in coupling mechanisms of insulin secretion. Physiol Rev 1987; 67: 1185-1248.
-
(1987)
Physiol Rev
, vol.67
, pp. 1185-1248
-
-
Prentki, M.1
Matschinsky, F.M.2
-
44
-
-
0026734115
-
Quality of life on antihypertensive therapy: A double-blind trial comparing quality of life on pinacidil and nifedipine in combination with a thiazide diuretic. European Pinacidil Study Group
-
Fletcher AE et al. Quality of life on antihypertensive therapy: a double-blind trial comparing quality of life on pinacidil and nifedipine in combination with a thiazide diuretic. European Pinacidil Study Group. J Cardiovasc Pharmacol 1992; 20: 108-114.
-
(1992)
J Cardiovasc Pharmacol
, vol.20
, pp. 108-114
-
-
Fletcher, A.E.1
-
45
-
-
0026666403
-
Simultaneous assessment of insulin secretion and insulin sensitivity using a hyperglycemic clamp
-
Mitrakou A et al. Simultaneous assessment of insulin secretion and insulin sensitivity using a hyperglycemic clamp. J Clin Endocrinol Metab 1992; 75: 379-382.
-
(1992)
J Clin Endocrinol Metab
, vol.75
, pp. 379-382
-
-
Mitrakou, A.1
-
46
-
-
0026601859
-
Patients with insulinoma show insulin resistance in the absence of arterial hypertension
-
Pontiroli AE, Alberetto M, Pozza G. Patients with insulinoma show insulin resistance in the absence of arterial hypertension. Diabetologia 1992; 35: 294-295.
-
(1992)
Diabetologia
, vol.35
, pp. 294-295
-
-
Pontiroli, A.E.1
Alberetto, M.2
Pozza, G.3
-
47
-
-
0025763533
-
Renal and cardiovascular effects of exogenous insulin in healthy volunteers
-
Gans ROB et al. Renal and cardiovascular effects of exogenous insulin in healthy volunteers. Clin Sci 1991; 80: 219-225.
-
(1991)
Clin Sci
, vol.80
, pp. 219-225
-
-
Gans, R.O.B.1
-
48
-
-
0026736333
-
Acute hyperinsulinemia induces sodium retention and a blood pressure decline in diabetes mellitus
-
Gans ROB et al. Acute hyperinsulinemia induces sodium retention and a blood pressure decline in diabetes mellitus. Hypertension 1992; 20: 199-209.
-
(1992)
Hypertension
, vol.20
, pp. 199-209
-
-
Gans, R.O.B.1
-
49
-
-
0027383905
-
Cardiovascular actions of insulin in humans. Implications for insulin sensitivity and vascular tone
-
Bailliere Tindall, London
-
Baron AD. Cardiovascular actions of insulin in humans. Implications for insulin sensitivity and vascular tone. In: Bailliere's Clinical Endocrinology and Metabolism. Bailliere Tindall, London, 1993, pp 961-987.
-
(1993)
Bailliere's Clinical Endocrinology and Metabolism
, pp. 961-987
-
-
Baron, A.D.1
-
50
-
-
0021932368
-
Effect of insulin on the distribution and disposition of glucose in man
-
Ferrannini E, Reichard G, Bevilacqua S. Effect of insulin on the distribution and disposition of glucose in man. J Clin Invest 1985; 76: 357-364.
-
(1985)
J Clin Invest
, vol.76
, pp. 357-364
-
-
Ferrannini, E.1
Reichard, G.2
Bevilacqua, S.3
-
51
-
-
9344261012
-
Effects of systemic hyperinsulinemia on muscle perfusion and glucose metabolism in man
-
Bonadonna R, Saccomani MP, Cobelli C. Effects of systemic hyperinsulinemia on muscle perfusion and glucose metabolism in man. Diabetes 1992; 41 (Suppl 1): 659.
-
(1992)
Diabetes
, vol.41
, Issue.1 SUPPL.
, pp. 659
-
-
Bonadonna, R.1
Saccomani, M.P.2
Cobelli, C.3
-
52
-
-
0028065421
-
Insulin blunts sympathetic vasoconstriction through the alpha 2-adrenergic pathway in humans
-
Lembo G et al. Insulin blunts sympathetic vasoconstriction through the alpha 2-adrenergic pathway in humans. Hypertension 1994; 24: 429-438.
-
(1994)
Hypertension
, vol.24
, pp. 429-438
-
-
Lembo, G.1
-
53
-
-
0000957230
-
Insulin stimulates gene transcription and activity of Na/K ATPase in vascular smooth muscle cells
-
Prakash TR, MacKenzie SH, Ram JL. Insulin stimulates gene transcription and activity of Na/K ATPase in vascular smooth muscle cells. Hypertension 1992; 20: 443.
-
(1992)
Hypertension
, vol.20
, pp. 443
-
-
Prakash, T.R.1
MacKenzie, S.H.2
Ram, J.L.3
-
54
-
-
0026036085
-
Hypertension in obesity and NIDDM. Role of insulin and sympathetic nervous system
-
Daly PA, Landsberg L. Hypertension in obesity and NIDDM. Role of insulin and sympathetic nervous system. Diabetes Care 1991; 14: 240-248.
-
(1991)
Diabetes Care
, vol.14
, pp. 240-248
-
-
Daly, P.A.1
Landsberg, L.2
-
55
-
-
0019483909
-
Effect of insulin and glucose infusions on sympathetic nervous system activity in normal man
-
Rowe JW, Young JB, Minaker KL. Effect of insulin and glucose infusions on sympathetic nervous system activity in normal man. Diabetes 1981; 30: 219-225.
-
(1981)
Diabetes
, vol.30
, pp. 219-225
-
-
Rowe, J.W.1
Young, J.B.2
Minaker, K.L.3
-
56
-
-
0026515392
-
Evidence against the hypothesis that hyperinsulinemia increases sympathetic nervous system activity in man
-
Mitrakou A et al. Evidence against the hypothesis that hyperinsulinemia increases sympathetic nervous system activity in man. Metabolism 1992; 41: 198-200.
-
(1992)
Metabolism
, vol.41
, pp. 198-200
-
-
Mitrakou, A.1
-
57
-
-
9344232326
-
Endogenous hyperinsulinemia does not elevate plasma catecholamines
-
Ligtenberg JJM et al. Endogenous hyperinsulinemia does not elevate plasma catecholamines. Diabetologia 1995; 38: A140.
-
(1995)
Diabetologia
, vol.38
-
-
Ligtenberg, J.J.M.1
-
58
-
-
0026518984
-
Insulin increases sympathetic activity but not blood pressure in borderline hypertensive humans
-
Anderson EA et al. Insulin increases sympathetic activity but not blood pressure in borderline hypertensive humans. Hypertension 1992; 19: 621-627.
-
(1992)
Hypertension
, vol.19
, pp. 621-627
-
-
Anderson, E.A.1
-
59
-
-
0025995364
-
Hyperinsulinemia produces both sympathetic neural activation and vasodilation in normal humans
-
Anderson EA, Hoffman RP, Balon TW. Hyperinsulinemia produces both sympathetic neural activation and vasodilation in normal humans. J Clin Invest 1991; 87: 2246-2252.
-
(1991)
J Clin Invest
, vol.87
, pp. 2246-2252
-
-
Anderson, E.A.1
Hoffman, R.P.2
Balon, T.W.3
-
60
-
-
0028260122
-
Acute noradrenergic activation induces insulin resistance in human skeletal muscle
-
Lembo G et al. Acute noradrenergic activation induces insulin resistance in human skeletal muscle. Am J Physiol 1994; 266: E242-E247.
-
(1994)
Am J Physiol
, vol.266
-
-
Lembo, G.1
|