Isolation and characterization of a monomethioninesulfoxide variant of interferon α-2b

Pharmaceutical Research

Volumn 13, Issue 5, 1996, Pages 762-769

  Gitlin, Gerry ^a   Tsarbopoulos, Anthony ^a   Patel, Suman T ^b   Sydor, Wasyl ^a   Pramanik, Birendra N ^a   Jacobs, Sheila ^a   Westreich, Louis ^a   Mittelman, Stanley ^a   Bausch, James N ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b BIOGEN   (United States)

Author keywords

Mass spectrometry; Methionine oxidation; Protein mapping

Indexed keywords

ALPHA INTERFERON DERIVATIVE; METHIONINE; PEPTIDE FRAGMENT; RECOMBINANT ALPHA2B INTERFERON;

ANTIVIRAL ACTIVITY; ARTICLE; ASSAY; CHEMICAL MODIFICATION; CIRCULAR DICHROISM; DRUG ACTIVITY; DRUG ISOLATION; DRUG PURITY; MASS SPECTROMETRY; NONHUMAN; OXIDATION; PEPTIDE MAPPING; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SEQUENCE ANALYSIS;

AMINO ACID SEQUENCE; ANTIVIRAL AGENTS; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIRCULAR DICHROISM; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; INTERFERON ALFA-2B; MASS SPECTROMETRY; METHIONINE; MOLECULAR SEQUENCE DATA; PEPTIDE MAPPING; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 0029885517     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1016059902645     Document Type: Article

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