Primary structural motifs of Conus peptides

Advances in Experimental Medicine and Biology

Volumn 391, Issue , 1996, Pages 155-167

  Cruz, Lourdes J ^a  

^a University of the Philippines Diliman   (Philippines)

Author keywords

[No Author keywords available]

Indexed keywords

CONOTOXIN; LIGAND; MARINE TOXIN; OMEGA CONOTOXIN; PEPTIDE;

AMINO ACID SEQUENCE; ARTICLE; CYANOSIS; DIAPHRAGM PARALYSIS; MARINE ENVIRONMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN ISOLATION; RESPIRATORY FAILURE; SNAIL; SPEECH DISORDER; UNCONSCIOUSNESS; VISUAL IMPAIRMENT;

EID: 0029885431     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4613-0361-9_9     Document Type: Article

References (62)

1. Abogadie, F. C., Ramilo, C. A., Corpuz, G. P. and Cruz, L. J. 1990. Biologically active poptides from Conus quercinus, a worm-hunting species. Trans. Natl. Acad. Sci. & Tech. (Philippines) 12:219-232.
2. 1-Conotoxin Gl. In: Peptides: Chemistry, Structure and Biology Eds. Rivier, J. E. and Marshall, G. R.). Leiden, Escom.
3. Becker, S., Prusak-Sochaczewski, E., Zamponi, G., Beck-Sickinger, A. G., Gordon, R. D. and French, R. J. 1992. Action of derivatives of μ-conotoxin GIHA on sodium channels. Single amino acid substitutions in the toxin separately affect association and dissociation rates. Biochemistry 31:8229-8238.
4. Cruz, L. J., Corpuz, G. and Olivera, B. M. 1976. A preliminary study of Conus venom protein. Veliger 18:302-308.
5. Cruz, L. J., Gray, W. R., Olivera, B. M., Zeikus, R. D., Kerr, L., Yoshikami, D. and Moczydlowski, E. 1985. Conus geographus toxins that discriminate between neuronal and muscle sodium channels. J. Biol. Chem. 260:9280-9288.
6. Cruz, L. J., Ramilo, C. A., Corpuz, G. P. and Olivera, B. M. 1992. Conus peptides: phylogenetic range of biological activity. Biol. Bull. 183:159-164.
7. Cruz, L. J. and White, J. 1995. Clinical toxicology of Conus snail stings. In: CRC Handbook on Clinical Toxicology of Animal Venoms and Poisons Eds. Meier, J. and White, J.). Boca Raton, FL, CRC Press, 117-127.
8. Davis, J. H., Bradley, E. K., Miljanich, G. P., Nadasdi, L., Ramachandran, J. and Basus, V. J. 1993. Solution structure of ω-conotoxin GVIA using 2-D NMR spectroscopy and relaxation matrix analysis. Biochemistry 32:7396-7405.
9. Endean, R. and Rudkin, C. 1963. Studies of the venoms of some Conidae. Toxicon 1:49-64.
10. Endean, R. and Rudkin, C. 1965. Further studies of the venoms of Conidae. Toxicon 2:225-249.
11. Fainzilber, M., Hasson, A., Oren, R., Burlingame, A. L., Gordon, D., Spira, M. E. and Zlotkin, E. 1994. New mollusc-specific α-conotoxins block Aplysia neuronal acetylcholine receptors. Biochemistry 33:9523-9529.
12. Fainzilber, M., Kofman, O., Zlotkin, E. and Gordon, D. 1994. A new neurotoxin receptor site on sodium channels is identified by a conotoxin that affects sodium channel inactivation in molluscs and acts as an antagonist in rat brain. J. Biol. Chem. 269:2574-2580.
13. Fainzilber, M., van der Schors, R., Lodder, J. C., Li, K. W., Geraerts, W. P. M. and Kits, K. S. 1995. New sodium channel-blocking conotoxins also affect calcium currents in Lymnaea neurons. Biochemistry 34:5364-5371.
14. Gray, W. R., Luque, A., Olivera, B. M., Barrett, J. and Cruz, L. J. 1981. Peptide toxins from Conus geographus venom. J. Biol. Chem. 256:4734-4740.
15. Gray, W. R., Middlemas, D. M., Zeikus, R., Olivera, B. M. and Cruz, L. J. 1985. Structure-activity relationships in α-conotoxins: A model. In: Peptides: Structure anid Function. The Ninth American Peptide Symposium Eds. Deber, C. M., Hruby, V. J. and Kopple, K. D.). Rockford, IL, Pierce Chemical Pubs. 823-932.
16. Gray, W. R., Olivera, B. M., Cruz, L. J. and Rivier, J. 1988. A model for "sleeper peptide" (conotoxin GV) and other Gla-containing molecules. In: Peptide Chemistry 1987 Eds. Shiba, T. and Sakakibara, S.). Osaka, Japan, Protein Research Foundation, 105-113.
17. Groebe, D. R., Dumm, J. M., Levitan, E. S. and Abramson, S. N. 1995. α-Conotoxins selectively inhibit one of the two acetylcholine binding sites of nicotinic receptors. Mol. Pharmacol. 48:105-111.
18. Haack, J. A., Rivier, J., Parks, T. N., Mena, E. E., Cruz, L. J. and Olivera, B. M. 1990. Conantokin T: a γ-carboxyglutamate-containing peptide with N-methyl-D-aspartate activity. J. Biol. Chem. 265:6025-6029.
19. Hann, R. M., Pagan, O. R. and Eterovic, V. A. 1994. The α-conotoxins GI and MI distinguish between the nicotinic acetylcholine receptor agonist sites while SI does not. Biochemistry 33:14058-14063.
20. Hashimoto, K., Uchida, S., Yoshida, H., Nishiuchi, Y. Sakakibara, S. and Yukari, K. 1989. Eur. J. Pharmacol. 118:351.
21. Hernandez, J.-F., Olivera, B. M., Cruz, L. J., Myers, R. A., Abbott, J. and Rivier, J. 1990. Synthesis, characterization and biological activity of conantokin-G analogs. In: UCLA Symposia Conference on Biochemical and Biomedical Engineering Synthetic Peptides: Approaches to Biological Problems Frisco, CO, February 22-March 4.
22. 2+ channels. Neuron 9:69-77.
23. Hillyard, D. R., Olivera, B. M., Woodward, S., Gray, W. R., Corpuz, G. P., Ramilo, C. A. and Cruz, L. J. 1989. A molluscivorous Conus toxin: conserved frameworks in conotoxins. Biochemistry 28:358-361.
24. Hopkins, C., Grilley, M., Miller, C., Shon, K.-J., Cruz, L. J., Gray, W. R., Dykert, J., Rivier, J., Yoshikami, D. and Olivera, B. M. 1995. A new family of Conus peptides targeted to the nicotinic acetylcholine receptor. J. Biol. Chem., in press.
25. 13 is essential for the activity of ω-conotoxin MVIIA and GVIA, specific N-type calcium channel blockers. Biochem. Biophys. Res. Comm. 206:449-454.
26. 13 is essential for the activity of ω-conotoxin GVIA, a peptide toxin for N-type calcium channel. J. Biol. Chem. 269:23876-23878.
27. 1H nuclear magnetic resonance spectroscopy and distance geometry calculations. Biochemistry 28:4853-4860.
28. 1H-NMR investigation of the tertiary structure of ω-conotoxin. In: Protein Chemistry 1987 Eds. Shiba, T. and Sakakibara, S.). Osaka, Japan, Protein Research Foundation. 85-88.
29. Kohn, A. J. 1963. Venomous marine snails of the genus Conus. In: Venomous and Poisonous Animals and Noxious Plants of the Pacific Region Eds. Keegan, H. C. and McFarlane, W. V.). Oxford, Pergamon Press, 83.
30. Kohn, A. J., Saunders, P. R. and Wiener, S. 1960. Preliminary studies on the venom of the marine snail Conus. Ann. N.Y. Acad. Sci. 90:706-725.
31. Lampe, R. A., Lo, M. M., Keith, R. A., Horn, M. B., McLane, M. W., Herman, J. L. and Spreen, R. C. 1993. Effects of site-specific acetylation on ω-conotoxin GV1A binding and function. Biochemistry 32:3255-3260.
32. Lancelin, J.-M., Kohda, D., Tate, S., Yanagawa, Y., Abe, T., Satake, M. and Inagaki, F. 1991. Tertiary structure of conotoxin GIIIA in aqueous solution. Biochemistry 30:6908-6916.
33. McIntosh, J. M., Hasson, A., Spira, M. E., Li, W., Marsh, M., Hillyard, D. R. and Olivera, B. M. 1995. A new family of conotoxins which block sodium channels. J. Biol. Chem. 270:16796-16802.
34. McIntosh, J. M., Olivera, B. M., Cruz, L. J. and Gray, W. R. 1984. γ-Carboxyglutamate in a neuroactive toxin. J. Biol. Chem. 259:14343-14346.
35. McIntosh, J. M., Yoshikami, D., Mahe, F., Nielsen, D. B., Rivier, J. F., Gray, W. R. and Olivera, B. M. 1994. A nicotinic acetylcholine receptor ligand of unique specificity, α-conotoxin ImI. J. Biol. Chem. 269:16733-16739.
36. McIntosh, M., Cruz, L. J., Hunkapiller, M. W., Gray, W. R. and Olivera, B. M. 1982. Isolation and structure of a peptide toxin from the marine snail Conus magus. Arch. Biochem. Biophys. 218:329-334.
37. Mena, E. F., Gullak, M. F., Pagnozzi, M. J., Richter, K. E., Rivier, J., Cruz, L. J. and Oivera, B. M. 1990. Conantokin-G: a novel peptide antagonist to the N-methyl-D-aspartate acid (NMDA) receptor. Neurosci. Lett. 118:241-244.
38. Myers, R. A. 1989. Toxins of Conus marine snails bind the nicotinic acetylcholine receptor at sites not identical to those of traditional antagonists. J. Neurosci. 15:678.
39. Myers, R. A., Cruz, L. J., Rivier, J. and Olivera, B. M. 1993. Conus peptides as chemical probes for receptors and ion channels. Chem. Rev. 93:1923-1936.
40. 2+ entry into neurons. J. Toxin.-Toxin Rev. 9:179-202.
41. Nishiuchi, Y. and Sakakibara, S. 1984. The structure-function relationship in conotoxins. In: Peptide Chemistry 1983 (Ed. Munekata, E.). Osaka, Japan, Protein Research Foundation. 191.
42. Olivera, B. M., Cruz, L. J., de Santos, V., LeCheminant, G. W., Griffin, D., Zeikus, M., McIntosh, J., Galcan, R., Varga, J., Gray, W. R. and Rivier, J. 1987. Neuronal calcium channel antagonists. Discrimination between calcium channel subtypes using ω-conotoxins from Conus magus venom. Biochemistry 26:2086-2090.
43. Olivera, B. M., Gray, W. R., Zeikus, R., McIntosh, J. M., Varga, J., Rivier, J., de Santos, V. and Cruz, L. J. 1985. Peptide neurotoxins from fish-hunting cone snails. Science 230:1338-1343.
44. Olivera, B. M., Imperial, J. S., Cruz, L. J., Bindokas, V. P., Venema, V. J. and Adams, M. E. 1991. Calcium channel-targeted polypeptide toxins. Ann. N.Y. Acad. Sci. 635:114-122.
45. Olivera, B. M., Johnson, D. S., Azimi-Zoonooz, A. and Cruz, L. J. 1992. Peptides in the venom of the geography cone, Conus geographus. In: Toxins and Targets Eds. Watters, D., Lavin, M., Maguire, D. and Pearn, J.). Victoria, Australia, Harwood Academic Publishers, 19-28.
46. Olivera, B. M., McIntosh, J. M., Cruz, L. J., Luque, F. A. and Gray, W. R. 1984. Purification and sequence of a presynaptic peptide toxin from Conus geographus venom. Biochemistry 23:5087-5090.
47. Olivera, B. M., Miljanich, G., Ramachandran, J. and Adams, M. E. 1994. Calcium channel diversity and neurotransmitter release: The ω-conotoxins and ω-agatoxins. Ann. Rev. Biochem. 63:823-867.
48. Olivera, B. M., Rivier, J., Clark, C., Ramilo, C. A., Corpuz, G. P., Abogadie, F. C., Mena, E. E., Woodward, S. R., Hillyard, D. R. and Cruz, L. J. 1990. Diversity of Conus neuropeptides. Science 249:257-263.
49. Pallaghy, P. K., Duggan, B. M., Pennington, M. W. and Norton, R. S. 1993. Three-dimensional structure in solution of the calcium channel blocker ω-conotoxin. J. Mol. Biol. 234:405-420.
50. Pallaghy, P. K., Nielsen, K. J., Craik, D. J. and Norton, R. S. 1994. A common structural motif incorporating a cystine knot and triple-stranded β-sheet in toxic and inhibitory polypeptides. Protein Sci. 3:1933-1839.
51. Pardi, A., Goldes, A., Florance, J. and Maniconte, D. 1989. Solution structures of α-conotoxins determined by two-dimensional NMR spectroscopy. Biochemistry 28:5494-5501.
52. Ramilo, C. A., Zafaralla, G. C., Nadasdi, L., Hammerland, L. G., Yoshikami, D., Gray, W. R., Ramachandran, J., Miljanich, G., Olivera, B. M. and Cruz, L. J. 1992. Novel α- and ω-conotoxins from Conus striatus venom. Biochemistry 31:9919-9926.
53. Sato, K., Ishida, Y., Wakamatsu, K., Kato, R., Honda, H., Ohizumi, Y., Nakamura, H., Ohya, M., Lancelin, J.-M., Kohda, D. and Inagaki, F. 1991. Active site μ-conotoxin GIIIA. a peptide blocker of muscle sodium channels. 266:16989-16991.
54. Sato, K., Ishida, Y., Wakamatsu, K., Ohizumi, Y., Kato, R., Honda, H. and Nakamura, H. 1990. Structure-activity relationship of geographutoxin (III). Search for an active site by the synthesis of a series of analogs substituted with a single alanine. Peptide Chemistry 1990, Osaka, Japan, Protein Research Foundation.
55. Sato, K., Park, N.-G., Kohno, T., Maeda, T., Kim, J. I., Kato, R. and Takahashi, M. 1993. Role of basic residues for the binding of ω-conotoxin GVIA to N-type calcium channels. Biochem. Biophys. Res. Comm. 194:1292-1296.
56. Sato, S., Nakamura, H., Ohizumi, Y. Kobayashi, J. and Hirata, Y. 1983. The amino acid sequences of homologous hydroxyproline containing myotoxins from the marine snail Conus geographus venom. FEBS Lett. 155:277-280.
57. Shon, K.-J., Hasson, A., Spira, M. E., Cruz, L. J., Gray, W. R. and Olivera, B. M. 1994. δ-Conotoxin GmVIA, a novel peptide from the venom of Conus gloriamaris. Biochemistry 33:11420-11425.
58. Skalicky, J. J., Metzler, W. J., Ciesla, D. J., Galdes, A. and Pardi, A. 1993. Solution structure of the calcium channel antagonist ω-conotoxin GVIA. Protein Sci. 2:1591-1603.
59. Wakamatsu, K., Kohda, D., Hatanaka, H., Lancelin, J.-M., Ishida, Y., Oya, M., Nakamura, H., Inagaki, F. and Sato, K. 1992. Structure-activity relationships of μ-conotoxin GIIIA: structure determination of active and inactive sodium channel blocker peptides by NMR and simulated annealing calculations. Biochemistry 31:12577-12584.
60. Yanagawa, Y., Abe, T., Satake, M., Odani, S., Suzuki, J. and Ishikawa, K. 1988. A novel sodium channel inhibitor from Conus geographus: Purification, structure, and pharmacological properties. Biochemistry 27:6256-6262.
61. Yoshiba, S. 1984. An estimation of the most dangerous species of cone shell Conus geographus venoms lethal dose in humans. Jpn. J. Hyg. 39:565.
62. Zafaralla, G. C., Ramilo, C., Gray, W. R., Karlstrom, R., Olivera, B. M. and Cruz, L. J. 1988. Phylogenetic specificity of cholinergic ligands: α-conotoxin SI. Biochemistry 27:7102-7105.