Role of N- and C-terminal substituents on the CCK-B agonist - Antagonist pharmacological profile of Boc-Trp-Phg-Asp-Nal-NH2 derivatives

Bioorganic and Medicinal Chemistry

Volumn 4, Issue 4, 1996, Pages 563-573

  Weng, Jian Hui ^a   Blommaert, Armand G S ^a   Moizo, Laurent ^b   Bado, André ^b   Ducos, Bertrand ^a   Böhme, Andreas ^c   Garbay, Christiane ^a   Roques, Bernard P ^a  

^a Laboratoire de Pharmacochimie   (France)

^b BICHAT HOSPITAL   (France)

^c SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

1 (2,3 DIHYDRO 1 METHYL 2 OXO 5 PHENYL 1H 1,4 BENZODIAZEPIN 3 YL) 3 (3 METHYLPHENYL)UREA; 2 ADAMANTYLOXYCARBONYL DEXTRO ALPHA METHYLTRYPTOPHYLPHENYLGLYCYL ASPARTYLNAPHTHYLALANIN AMIDE; 4 [[2 [2 [[(2 ADAMANTYLOXY)CARBONYL]AMINO] 3 (1H INDOL 3 YL) 2 METHYLPROPIONAMIDO] 1 PHENYLETHYL]AMINO] 4 OXOBUTYRIC ACID MEGLUMINE; CHOLECYSTOKININ B RECEPTOR; CHOLECYSTOKININ DERIVATIVE; CHOLECYSTOKININ OCTAPEPTIDE; INOSITOL PHOSPHATE; L 134308; PD 365260; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; CHO CELL; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; ELECTROPHYSIOLOGY; GUINEA PIG; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; PANCREAS; PROTEIN MODIFICATION; RAT; REGIONAL PERFUSION; STOMACH ACID SECRETION; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; ANTI-ANXIETY AGENTS; BENZODIAZEPINONES; CHO CELLS; CHOLECYSTOKININ; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHYSIOLOGY; GASTRIC ACID; GASTROINTESTINAL AGENTS; HIPPOCAMPUS; INDOLES; INOSITOL PHOSPHATES; MALE; MEGLUMINE; MOLECULAR SEQUENCE DATA; NEURONS; NEUROTRANSMITTER AGENTS; OLIGOPEPTIDES; PENTAGASTRIN; PHENYLUREA COMPOUNDS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, CHOLECYSTOKININ B; RECEPTORS, CHOLECYSTOKININ; STRUCTURE-ACTIVITY RELATIONSHIP; TIME FACTORS; TRANSFECTION;

ANIMALIA; CAVIA PORCELLUS; SUS SCROFA;

EID: 0029885156     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/0968-0896(96)00050-8     Document Type: Article

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