(S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine [(S)-HPMPA]: A purine analogue with trypanocidal activity in vitro and in vivo

Tropical Medicine and International Health

Volumn 1, Issue 2, 1996, Pages 255-263

  Kaminsky, Ronald ^a   Schmid, Cecile ^a   Grether, Yvonne ^a   Holý, Antonin ^b   De Clercq, Erik ^c   Naesens, Lieve ^c   Brun, Reto ^a  

^a SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

^b INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

^c REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

(S) HPMPA; African trypanosomes; Chemotherapy; Cytotoxicity; In vitro assays; Purines

Indexed keywords

9 (3 HYDROXY 2 PHOSPHONOMETHOXYPROPYL)ADENINE; ANTITRYPANOSOMAL AGENT; PURINE DERIVATIVE;

ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; IN VITRO STUDY; LEISHMANIA DONOVANI; LEISHMANIASIS; NONHUMAN; TRYPANOSOMA; TRYPANOSOMA BRUCEI; TRYPANOSOMA CONGOLENSE; TRYPANOSOMA CRUZI; TRYPANOSOMA RHODESIENSE; TRYPANOSOMIASIS;

EID: 0029885033     PISSN: 13602276     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-3156.1996.tb00036.x     Document Type: Article

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