Impact of the stereochemistry of benzo[a]pyrene 7,8-dihydrodiol 9,10-epoxide-deoxyadenosine adducts on resistance to digestion by phosphodiesterases I and II and translesion synthesis with HIV-1 reverse transcriptase

Chemical Research in Toxicology

Volumn 9, Issue 2, 1996, Pages 409-417

  Chary, Parvathi ^a   Lloyd, R Stephen ^a  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS 1; SERPENTES;

BENZO[A]PYRENE 7,8 DIHYDRODIOL 9,10 OXIDE; BENZO[A]PYRENE DERIVATIVE; DEOXYADENOSINE; DNA; OLIGODEOXYNUCLEOTIDE; PHOSPHODIESTERASE I; RNA DIRECTED DNA POLYMERASE; SNAKE VENOM; SPLEEN EXONUCLEASE; UNCLASSIFIED DRUG;

ARTICLE; CHIRALITY; DNA ADDUCT; DNA REPLICATION; DRUG RESISTANCE; ENZYME MECHANISM; ENZYME SYNTHESIS; SPLEEN CELL; STEREOISOMERISM; TOXIN ANALYSIS;

7,8-DIHYDRO-7,8-DIHYDROXYBENZO(A)PYRENE 9,10-OXIDE; DEOXYADENOSINES; DNA ADDUCTS; HIV-1; PHOSPHORIC DIESTER HYDROLASES; RNA-DIRECTED DNA POLYMERASE; SNAKE VENOMS; SPLEEN; STEREOISOMERISM;

EID: 0029884985     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx950012b     Document Type: Article

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