Anti-idiotypic response to antigrowth factor receptor monoclonal antibodies

European Journal of Cancer

Volumn 32, Issue 3, 1996, Pages 498-505

  Tosi, E ^a   Valota, O ^a,c   Canevari, S ^a   Adobati, E ^a   Casalini, P ^a   Perez, P ^b   Colnaghi, M I ^a  

^a NATIONAL CANCER INSTITUTE   (Italy)

^b UNIVERSITY OF SALAMANCA   (Spain)

^c Pharmacia FICE   (Spain)

Author keywords

EGF R; Growth factor receptor; HER 2 neu; Idiotype; Monoclonal antibodies

Indexed keywords

EPIDERMAL GROWTH FACTOR ANTIBODY; GROWTH FACTOR RECEPTOR; IDIOTYPIC ANTIBODY; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; MOUSE; NONHUMAN; ONCOGENE NEU; PRIORITY JOURNAL; TUMOR CELL;

ANIMALS; ANTIBODIES, ANTI-IDIOTYPIC; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; BREAST NEOPLASMS; FEMALE; HUMANS; LUNG NEOPLASMS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; OVARIAN NEOPLASMS; RECEPTORS, GROWTH FACTOR; TUMOR CELLS, CULTURED;

EID: 0029884983     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/0959-8049(95)00561-7     Document Type: Article

References (38)

1. Jerne NK. Towards a network theory of the immune system. Ann Immunol 1974, 125, 373-389.
2. Cazenave P. Idiotypic-anti-idiorypic regulation of antibody synthesis in rabbits. Proc Natl Acad Sci USA 1977, 74, 5122-5125.
3. Nisonoff A. Idiotypes: concepts and applications. J Immunol 1991, 147, 2429-2438.
4. Greenspan NS, Bona CA. Idiotypes: structure and immunogenicity. FASEB J 1993, 7, 437-444.
5. Kusama M, Kageshita T, Chen ZJ, Ferrone S. Characterization of syngeneic antiidiotypic monoclonal antibodies to murine anti-human melanoma high molecular weight melanoma-associated antigen monoclonal antibodies. J Immunol 1989, 143, 3844-3852.
6. Bhattacharya-Chatterjee M, Mukerjee S, Biddle W, Foon KA, Kohler H. Murine monoclonal anti-idiotype antibody as a potential network antigen for human carcinoembryonic antigen. J Immunol 1990, 145, 2758-2765.
7. Miotti S, Mantovani L, Pupa SM, Bellosta P, Colnaghi MI. Characterization of two anti-idiotypic monoclonal antibodies raised against the anti-tumor monoclonal antibody MOv18. J Immunol Res 1989, 1, 59-65.
8. Pupa SM, Bazzini P, Ménard S, Colnaghi MI. Network of idiotypic and anti-idiotypic antibodies related to the ovarian carcinoma-associated folate binding protein. Anticancer Res 1992, 12, 1565-1570.
9. Chen ZJ, Yang H, Liu CC, Hirai S, Ferrone S. Modulation by adjuvants and carriers of the immunogenicity in xenogeneic hosts of mouse anti-idiotypic monoclonal antibody MK2-23, an internal image of human high molecular weight-melanoma associated antigen. Cancer Res 1993, 53, 112-119.
10. Mittelman A, Chen ZJ, Kageshita T, et al. Active specific immunotherapy in patients with melanoma. J Clin Invest 1990, 86, 2136-2144.
11. Mittelman A, Chen ZJ, Yang H, Wong GY, Ferrone S. Human high molecular weight-melanoma associated antigen (HMW-MAA) mimicry by mouse anti-idiotypic monoclonal antibody MK2-23: induction of humoral anti-HMW-MAA immunity and prolongation of survival in patients with stage IV melanoma. Proc Natl Acad Sci USA 1992, 89, 466-470.
12. Herlyn D, Wettendorff M, Schmoll E, et al. Anti-idiotype immunization of cancer patients: modulation of the immune response. Proc Natl Acad Sci USA 1987, 84, 8055-8059.
13. Steplewski Z, Fox K, Glick J, Koprowski H. Human antimouse antibody response in patients treated with multiple infusions of monoclonal antibody CO17-1A. In Vaeth JM, Meyer JL, eds. The Presence and Future Role of Monoclonal Antibodies in the Management of Cancer. Ther Radiat Ther Oncol, Vol. 24. Basel, Karger, 1990, 69-72.
14. Mittelman A, Chen ZJ, Liu CC, Hirai S, Ferrone S. Kinetics of the immune response and regression of metastatic lesions following development of humoral anti-high molecular weight-melanoma associated antigen immunity in three patients with advanced malignant melanoma immunized with mouse antiidiotypic monoclonal antibody MK2-23. Cancer Res 1994, 54, 415-421.
15. Ferrone S, Chen ZJ, Liu CC, Hirai S, Kageshita T, Mittelman A. Human high molecular weight-melanoma associated antigen mimicry by mouse anti-idiotypic monoclonal antibodies MK2-23. Experimental studies and clinical trials in patients with malignant melanoma. Pharmac Ther 1993, 57, 259-290.
16. Aaronson SA. Growth factors and cancer. Science 1991, 254, 1146-1153.
17. Gullick WJ. Prevalence of aberrant expression of the epidermal growth factor receptor in human cancers. Br Med Bull 1991, 47, 87-98.
18. Volm M, Efferth T, Mattern J. Oncoprotein (c-myc, c-erbB1, c-erbB2, c-fos) and suppressor gene product (p53) expression in squamous cell carcinomas of the lung. Clinical and biological correlations. Anticancer Res 1992, 12, 11-20.
19. Slamon DJ, Godolphin W, Jones LA, et al. Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 1989, 244, 707-712.
20. Rilke F, Colnaghi MI, Cascinelli N, et al. Prognostic significance of HER-2/neu expression in breast cancer and its relationship to other prognostic factors. Int J Cancer 1991, 49, 44-49.
21. Tosi E, Valota O, Negri DRM, et al. Antitumor efficacy of an anti-epidermal growth factor receptor monoclonal antibody and its F(ab′)2 fragment against high and low EGFR-expressing carcinomas in nude mice. Int J Cancer 1995, 62, 643-650.
22. HER2 and growth inhibition of cells with HER2/neu gene amplification. Int J Cancer 1991, 47, 933-937.
23. Centis F, Tagliabue E, Uppugunduri S, et al. p185 HER2/neu epitope mapping with murine monoclonal antibodies. Hybridoma 1992, 11, 267-276.
24. Miotti S, Canevari S, Ménard S, et al. Characterization of human ovarian carcinoma-associated antigens defined by novel monoclonal antibodies with tumor-restricted specificity. Int J Cancer 1987, 39, 297-303.
25. Marchalonis JJ. An enzymatic method for the trace iodination of immunoglobulin and other proteins. Biochem J 1969, 113, 299-305.
26. Gullick WJ, Downward J, Waterfield MD. Antibodies to the autophosphorylation sites of the epidermal growth factor receptor protein-tyrosine kinase as probes of structure and function. EMBO J 1985, 4, 2869-2877.
27. Ménard S, Tagliabue E, Canevari S, Fossati G, Colnaghi MI. Generation of monoclonal antibodies reacting with normal and cancer cells of human breast. Cancer Res 1983, 43, 1295-1300.
28. Crippa F, Bolis G, Seregni E, et al. Single dose intraperitoneal radioimmunotherapy with the murine monoclonal antibody 1311-MOv18: clinical results in patients with minimal residual disease of ovarian cancer. Eur J Cancer 1995, 31A, 686-690.
29. Viale G, Grassi F, Pelagi M, et al. Anti-human tumor antibodies induced in mice and rabbits by "internal image" anti-idiotypic monoclonal immunoglobulins. J Immunol 1987, 139, 4250-4255.
30. Chen ZJ, Yang H, Ferrone S. Human high molecular weight melanoma-associated antigen mimicry by mouse antiidiotypic monoclonal antibody MK2-23: characterization of the immunogenicity in syngeneic hosts. J Immunol 1991, 147, 1082-1090.
31. Colzanì E, Pupa SM, Bazzini P, et al. Study of the suitability of the immunological approach to detect new oncogene products. J Immunol Res 1992, 4, 73-78.
32. Li J-L, Chen J-L, Ouyang M-H, et al. Immunization strategies for the production of rat monoclonal anti-idiotope antibodies. J Immunol Methods 1991, 142, 15-20.
33. Micheel B, Scharte G. Multiple antigen injections decrease the yield of hybridomas producing monoclonal antibodies. Hybridoma 1993, 12, 227-229.
34. Dougall WC, Qian X, Peterson NC, Miller MJ, Samanta A, Greene MI. The neu-oncogene: signal transduction pathways, transformation mechanisms and evolving therapies. Oncogene 1994, 9, 2109-2123.
35. Montelione GT, Wüthrich K, Nice EC, Burgess AW, Scheraga HA. Identification of two anti-parallel b-sheet conformations in the solution structure of murine epidermal growth factor by proton magnetic resonance. Proc Natl Acad Sci USA 1986, 83, 8594-8598.
36. Cooke RM, Wilkinson AJ, Baron M, et al. The solution structure of human epidermal growth factor. Nature 1987, 327, 339-341.
37. Komoriya A, Hortsch M, Meyers C, Smith M, Kanety H, Schlessinger J. Biologically active synthetic fragments of epidermal growth factor: localization of a major receptor-binding region. Proc Natl Acad Sci USA 1984, 81, 1351-1355.
38. Khazaeli MB, Conry RM, LoBuglio AF. Human immune response to monoclonal antibodies. J Immunother 1994, 15, 42-52.