Continued desensitization of the pituitary gland in young bulls after treatment with the luteinizing hormone-releasing hormone agonist deslorelin

Biology of Reproduction

Volumn 54, Issue 4, 1996, Pages 769-775

  Bergfeld, E G M ^a,b   D'Occhio, M J ^a   Kinder, J E ^b  

^a CSIRO   (Australia)

^b UNIVERSITY OF NEBRASKA LINCOLN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DESLORELIN; GONADORELIN AGONIST; LUTEINIZING HORMONE; TESTOSTERONE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DESENSITIZATION; HORMONAL REGULATION; HORMONE ACTION; HORMONE RESPONSE; HYPOPHYSIS; LUTEINIZING HORMONE BLOOD LEVEL; LUTEINIZING HORMONE RELEASE; MALE; NONHUMAN; PRIORITY JOURNAL; TESTOSTERONE BLOOD LEVEL;

AMINO ACID SEQUENCE; ANIMALS; CATTLE; DRUG IMPLANTS; GONADOTROPIN-RELEASING HORMONE; LUTEINIZING HORMONE; MALE; MOLECULAR SEQUENCE DATA; PITUITARY GLAND; RADIOIMMUNOASSAY; TESTIS; TESTOSTERONE; TRIPTORELIN;

EID: 0029883902     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod54.4.769     Document Type: Article

References (21)

1. Melson BE, Brown JL, Schoenemann HM, Tarnavsky GK, Reeves JJ. Elevation of serum testosterone during chronic LHRH agonist treatment in the bull J Anim Sci 1986, 62 199-207
2. Rechenberg MV, Sandow J, Klatt P. Effect of long-term infusion of an LH-releasing hormone agonist on testicular function in bulls J Endocrinol 1986, 109 R9-R11
3. Ronayne E, Enright WJ, Roche JF. Effects of continuous administration of gonadotropin-releasing hormone (GnRII) or a potent GnRH analogue on blood luteinizing hormone and testosterone concentrations in prepubertal bulls Domest Anim Endocrinol 1993; 10:179-189
4. D'Occhio MJ, Aspden WJ Characteristics of luteinizing hormone (LH) and testosterone secretion, pituitary responses to LH-releasing hormone (LHRH) and reproductive function in young bulls receiving the LHRH agonist deslorelin effect of castration on LH responses to LHRH Biol Reprod 1996, 54:45-52
5. D'Occhio MJ, van Reenen N, Vermooten JADM, Garozzo SM, Aspden WJ, Trigg TE, Walsh J Maintenance of plasma LH and increased testosterone output in bulls receiving the GnRH agonist deslorelin is not dependent on GnRH-stimulated LH secretion Proc Endocrinol Soc Aust 1992, 35 86 (Abstract 55).
6. Bergfeld EGM, D'Occhio MJ, Kinder JE Pituitary function, ovarian follicular growth, and plasma concentrations of 17β estradiol and progesterone in prepubertal heifers during and after treatment with the luteinizing hormone-releasing hormone agonist deslorelin Biol Reprod 1996; 54:776-782
7. Lunn SF, Cowen GM, Morris KD Fraser HM. Influence of the gonad on the degree of suppression induced by an LHRH agonist implant in the marmoset monkey J Endocrinol 1992; 132 217-224.
8. Smitz J, Erard P, Camus M, Devroey P, Tournaye H, Wisanto A, Van Stierteghem AC Pituitary gonadotrophin secretory capacity during the luteal phase in superovulation using GnRH-agonists and HMG in a desensitization of flare-up protocol. Hum Reprod 1992, 7.1225-1229.
9. Mann DR, Gould KG, Collins DC Influence of continuous gonadotropin-releasing hormone (GnRII) agonist treatment on luteinizing hormone and testosterone secretion, the response to GnRH, and the testicular response to human chorionic gonadotropin in male rhesus monkeys J Clin Endocrinol & Metab 1984, 58:262-267
10. Vale W, Rivier C, Brown M, Ling N, Monahan M, Rivier J Pharmacology of hypothalamic regulatory peptides Clin Endocrinol 1976; 5(suppl) 261
11. Hejl KM, Wolfe MW, Kinder JE, Grotjan HE Bioactive and immunoreactive concentrations of circulating luteinizing hormone during sexual maturation in the bovine Biol Reprod 1992, 46:1205-1210
12. D'Occhio MJ, Gifford DR, Weatherly T, Setchell BP. Evidence of gonadal steroid-independent changes in activity of the central LH-releasing hormone pulse generator in developing bull calves J Endocrinol 1986, 111 67-73
13. D'Occhio MJ, Brooks DE Seasonal changes in plasma testosterone concentration and mating activity in Border Leicester, Poll Dorset, Romney and Suffolk rams. Aust J Exp Agric Anim Husb 1983; 23:248-253.
14. SAS SAS/STAT User's Guide, Volume 2, GLM-VARCOMP, Version 6, Fourth Edition Cary, NC. Statistical Analysis System Institute, Inc., 1990: 891-996.
15. SAS SAS/STAT Technical Report P-229, SAS/STAT Software Changes and Enhancements, Release 6.07 Cary, NC. Statistical Analysis System Institute, Inc , 1992: 287-368.
16. Lincoln GA, Fraser HM, Abbott MP Blockade of pulsatile LH, FSH and testosterone secretion in rams by constant infusion of an LHRH agonist J Reprod Fertil 1986; 77:587-597.
17. Huhtamemi I, Venho P, Jacobi G, Rannikko S. Response of circulating gonadotropin levels to GnRH agonist treatment in prostatic cancer. J Androl 1991; 12 46-53.
18. Meldrum DR, Tsao Z, Monroe SE, Braunstein GD, Sladek J, Lu JKH, Vale W, Rivier J, Judd, HL, Chang RJ. Stimulation of LH fragments with reduced bioactivity following GnRH agonist administration in women. J Clin Endocrinol & Metab 1984; 58:755-757.
19. Sharpe RM Regulation of spermatogenesis In Knobil E Neill JD (eds), The Physiology of Reproduction New York. Raven Press: 1994: 1363-1434
20. Kakar SS, Rahe CH, Neill JD Molecular cloning, sequencing, and characterizing the bovine receptor for gonadotropin releasing hormone (GnRH). Domest Anim Endocrinol 1993; 10.335-342
21. D'Occhio MJ, Setchell BP Pituitary and testicular responses in sexually mature bulls after intravenous injection of graded doses of LH-releasing hormone. J Endocrinol 1984; 103.371-376