Induction therapy with all-trans retinoic acid for acute promyelocytic leukemia: A clinical study of 10 cases, including a fetal case with thromboembolism

Internal Medicine

Volumn 35, Issue 1, 1996, Pages 10-14

  Tsukada, Nobuhiro ^a   Wada, Ken ^a   Aoki, Sadao ^a   Hashimoto, Shigeo ^a   Kishi, Kenji ^a   Takahashi, Masuhiro ^a   Koike, Tadashi ^a   Takahashi, Hoyu ^a   Shibata, Akira ^a  

^a NIIGATA UNIVERSITY   (Japan)

Author keywords

antifibrinolytics; daunorubicin (DNR); thrombosis

Indexed keywords

ANTINEOPLASTIC AGENT; CYTARABINE; DAUNORUBICIN; ENOCITABINE; HISTAMINE; MERCAPTOPURINE; PREDNISOLONE; RETINOIC ACID; TRANEXAMIC ACID;

ACUTE MYELOBLASTIC LEUKEMIA; ADULT; AGED; ANOREXIA; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FATALITY; FEMALE; HUMAN; HYPOTENSION; INTRAVENOUS DRUG ADMINISTRATION; MALE; STOMACH ULCER; THROMBOEMBOLISM; THROMBOSIS;

EID: 0029883884     PISSN: 09182918     EISSN: None     Source Type: Journal    
DOI: 10.2169/internalmedicine.35.10     Document Type: Article

References (26)

1. Bernard J, Weil M, Boiron M, Jacquillat C, Flandrin G, German MF. Acute promyelocytic leukemia. Results of treatment with daunorubicin. Blood 41: 489, 1973.
2. Cunningham I, Gee T, Reich L, Kempin S, Naval A, Clarkson B. Acute promyelocytic leukemia: Treatment results during a decade at Memorial hospital. Blood 73: 1116, 1989.
3. Sanz M, Jarque I, Martin G, et al. Acute promyelocytic leukemia. Therapy results and prognostic factors. Cancer 61: 7, 1988.
4. Cordonnier C, Vernant JP, Brun B, et al. Acute promyelocytic leukemia in 57 previously untreated patients. Cancer 55: 18, 1985.
5. Drapkin RL, Gee RS, Dowling MD, et al. Prophylactic heparin therapy in acute promyelocytic leukemia. Cancer 41: 2484, 1978.
6. Scrobohaci ML, Dombret H, Ghorra P, et al. Disseminated intravascular coagulation (DIC), and/or primary fibrinolysis in acute promyelocytic leukemia. Effect of all-trans retinoic acid treatment. Blood 78: 48, 1991 (Abstract).
7. Tallman M, Kwann H. Researching the hemostatic disorder associated with acute promyelocytic leukemia. Blood 73: 543, 1992.
8. Dombret H, Sutton L, Durarte M, et al. Combined therapy with all-trans retinoic acid and high-dose chemotherapy in patients with hyperleukocytic leukemia and severe hemorrhage Leukemia 6: 1237, 1992.
9. Dombret H, Scrobohaci ML, Ghorra P, et al. Coagulation disorders associated with acute promyelocytic leukemia: Corrective effects of all-trans retinoic acid treatment. Leukemia 7: 2, 1993.
10. Wijermans PW, Rebel VI, Ossenkoppele GJ, Huijgens PC, Langenhuijsen MMAC. Combined procoagulant activity and proteolytic activity of acute promyelocytic leukemia cells. Reversal of the bleeding disorder by cell differentiation. Blood 73: 800, 1989.
11. Huang M, Yu-Chen Y, Shu-Rong C, et al. Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia. Blood 72: 567, 1988.
12. Warrell RP Jr, Frankel SR, Miller WH, et al. Differentiation therapy of acute promyelocytic leukemia with tretinoin (all-rrans retinoic acid). N Engl J Med 324: 1385, 1991.
13. Chen Z-X, Xue Y-Q, Zhang R, et al. A clinical and experimental study on all-trans retinoic acid-treated acutepromyelocytic leukemia patients. Blood 78: 1413, 1991.
14. Bennett JM, Catovsky D, Daniel MT, et al. Proposal for the classification of acute leukemias. Br J Haematol 33: 4151, 1976.
15. Hashimoto S, Koike T, Tsukada N, Takahashi H, Arakawa M, Shibata A. Fetal thromboembolism in acute promyelocytic leukemia during all-trans retinoic acid therapy combined with antifibrinolytic therapy for prophylaxis of hemorrhage. Leukemia 7: 1113, 1994.
16. Koike T, Tatewaki W, Aoki A, et al. Severe symptoms of hyperhistaminemia after the treatment of tretinoin (all-trans retinoic acid). N Engl J Med 327: 385, 1992.
17. Warrell RP Jr, Maslak P, Eardley A, Heller G, Miller WH Jr, Frankel SR. Treatment of acute promyelocytic leukemia with all-trans retinoic acid: An update of the New York Experience. Leukemia 8: 929, 1994.
18. Ohno R, Yoshida H, Fukutani H, et al. Multi-institutional study of all-trans retinoic acid as a differentiation therapy of refractory acute promyelocytic leukemia. Leukemia 7: 1722, 1993.
19. Kanarnaru A, Takemoto Y, Tanimoto M, et al. All-trans retinoic acid for the treatment of newly diagnosed acute promyelocytic leukemia. Blood 85: 1202, 1995.
20. Runde V, Aul C, Heyll A, Schneider W. All-trans retinoic acid; Not only a differentiating agent, but also an inducer of thromboembolic events in patients with M3 leukemia. Blood 79: 534, 1992.
21. De Lacerda JF, Do Carmo JA, Guerra ML, Geraldes J, De Lacerda JMF. Multiple thrombosis in acute promyelocytic leukemia after tretinoin. Lancet 342: 114, 1993.
22. Rodeghiero F, Avvisati G, Castaman G, Barbui T, Mandelli F. Early deaths and anti-hemorrhagic treatments in acute promyelocytic leukemia. A GIMEMA retrospective study in 268 consecutive patients. Blood 75: 2112, 1990.
23. Avvisati G, ten Cate JW, Buller HR, Mandelli F. Tranexamic acid for control of haemorrhage in acute promyelocytic leukemia. Lancet 334: 122, 1989.
24. Avvisati G, ten Cate JW, Sturk A, Lamping R, Petti MC, Mandelli F Acquiredalpha-2-anriplasmin deficiency in acute promyelocytic leukemia. Br J Haematol 70: 43, 1988
25. Fenaux P, Castaigne S, Dombret H, et al. All-trans retinoic acid followed by intensive chemotherapy gives a high complete remission rate and may prolong remissions in newly diagnosed acute promyelocytic leukemia; A pilot study on 26 cases. Blood 80: 2176, 1992.
26. Miller WH Jr, Levine K, DeBlasio A, Frankel SR, Dmitovsky E, Warrell RP Jr. Detection of minimal residual disease in acute promyelocytic leukemia by a reverse transcription polymerase chain reaction assay for the PML-RAR-α fusion mRNA. Blood 82: 1689, 1993.