C-erbB-2, PCNA und histomorphologische Faktoren beim Mammakarzinom nach Einnahme oraler Kontrazeptiva

Pathologe

Volumn 17, Issue 3, 1996, Pages 202-207

  Schonborn I ^a   Minguillon, C ^a   Zschiesche, W ^b   Mohner M ^c   Ebeling, K ^d  

^a HUMBOLDT UNIVERSITY   (Germany)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

^d Berlin Niederschönhausen ^*

Author keywords

[No Author keywords available]

Indexed keywords

CHLORMADINONE ACETATE; CYCLINE; ESTROGEN RECEPTOR; ETHINYLESTRADIOL; LEVONORGESTREL; MESTRANOL; NORETHISTERONE ACETATE; ORAL CONTRACEPTIVE AGENT; PROGESTERONE RECEPTOR;

ARTICLE; BREAST CARCINOMA; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; ONCOGENE C ERB; ORAL DRUG ADMINISTRATION; PROGNOSIS;

ADULT; BREAST; BREAST NEOPLASMS; CELL TRANSFORMATION, NEOPLASTIC; CONTRACEPTIVES, ORAL, HORMONAL; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LYMPHATIC METASTASIS; MIDDLE AGED; NEOPLASM STAGING; PROGNOSIS; PROLIFERATING CELL NUCLEAR ANTIGEN; RECEPTOR, ERBB-2; TUMOR MARKERS, BIOLOGICAL;

EID: 0029882976     PISSN: 01728113     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002920050156     Document Type: Article

References (30)

1. Aaltoma S, Lipponen P, Papinaho S, Syrjänen K (1993) Proliferating-cell nuclear antigen (PC10) immunolabeling and other proliferation indices as prognostic factors in breast cancer. J Cancer Clin Oncol 119: 288-294
2. Bloom HJG, Richardson WW (1957) Histological grading and prognosis of breast cancer. A study of 1409 cases of which 359 have been followed for 15 years. Br J Cancer 11: 359-377
3. Cole PT (1977) Oral contraceptives and breast neoplasia. Cancer 39: 1906-1908
4. Correa P, Johnson WD (1978) International variation in the histology of breast carcinoma. UICC Techn Rep Series 35: 36-65
5. Donegan WL, Perez-Meza EM (1972) Lobular carcinoma - an indication for elective biopsy of the second breast. Am Surg 176: 178-185
6. Ebeling K, Ray R, Nischan P, Thomas DB, Kunde D, Stalsberg H (1991) Combined oral contraceptives containing chlormadinone acetate and breast cancer: results of a case-control study. Br J Cancer 63: 804-808
7. Fisher ER, Taylor M (1973) Changing patterns of some pathologic parameters of mammary carcinomas. Cancer 32: 1380-1384
8. Freiss G, Prébois Ch, Vignon F (1993) Control of breast cancer cell growth by steroids and growth factors: interactions and mechanisms. Breast Cancer Res Treat 27: 67-68
9. Fuqua SAW (1993) Abnormalities of the estrogen receptor in breast cancer-introduction. Breast Cancer Res Treat 26: 117-118
10. Horwitz KB (1993) Mechanisms of hormone resistance in breast cancer. Breast Cancer Res Treat 26: 119-130
11. Hulman G, Trowbridge P, Taylor CN, Chilvers CED, Sloane JP, UK National Case-Control Study Group (1992) Oral contraceptive use and histopathology of cancerous breast in young women. J Pathol 167: 407-411
12. Jeng MH, Parker CJ, Jordan VC (1992) Estrogenic potential of progestins in oral contraceptives to stimulate human breast cancer cell proliferation. Cancer Res 52: 6539-6546
13. King RJB (1993) Estrogen and progestin effects in human breast carinogenesis. Breast Cancer Res Treat 27: 3-15
14. Markopoulos C, Berger U, Wilson P, Gazet JC, Coombes RC (1988) Oestrogen receptor content of normal breast cells and breast carcinomas throughout the menstrual cycle. Br Med J 296: 1349-1351
15. Martinez V, Azzopardi JG (1979) Invasive lobular carcinoma of the breast: incidence and variations. Histopathology 3: 467-488
16. Matthews PN, Millis RR, Hayward JL (1981) Breast cancer in women who have taken contraceptive steroids. Br Med J 282: 774-776
17. Miller N, McPherson K, Jones L, Vessey M (1989) Histopathology of breast cancer in young women in relation to use of OCs. J Clin Pathol 42: 387-390
18. Olsson H, Borg A. Fernö M, Ranstam J, Sigurdsson H (1991) Her-2/neu and INT2 protooncogene amplification in malignant breast tumors in relation to reproductive factors and exposure to exogenous hormones. J Natl Cancer Inst 83: 1483-1487
19. Olsson H, Ranstam J, Baldetorp B, Ewers SB, Fernö M, Killander D, Sigurdsson H (1991) Proliferation and DNA ploidy in malignant breast tumors in relation to early oral contraceptive use and early abortions. Cancer 67: 1282-1290
20. O'Malley BW (1991) Steroid hormone receptors as transactivators of gene expression. Breast Cancer Res Treat 18: 67-71
21. Perren TJ (1991) C-erbB-2 oncogene as a prognostic marker in breast cancer. Br J Cancer 63: 328-332
22. Potten CS, Watson RJ, Williams GT, Tickle S, Roberts SA, Harris M, Howell A (1988) The effect of age and menstrual cycle upon proliferative activity of the normal human breast. Br J Cancer 58: 163-170
23. Rosen PP, Ashikari R, Thaler H, Ishikawa S, Hirota T, Abe O, Yamamoto H, Beattie EJ, Urban JA, Mike V (1977) A comparative study of some pathologic features of mammary carcinoma in Tokyo, Japan and New York, USA. Cancer 39: 429-434
24. Ruttemann GR (1992) Contraceptive steroids and the mammary gland: is there a hazard? - insights from animal studies. Breast Cancer Res Treat 23: 29-41
25. Schönborn I, Zschiesche W, Minguillon C, Spitzer E, Möhner M, Ebeling K, Grosse R (1995) Prognostic value of proliferating cell nuclear antigen and c-erbB-2 compared with conventional histopathological factors in breast cancer. J Cancer Res Clin Oncol 121: 115-122
26. Stalsberg H, Thomas DB, Noonan EA, WHO Collaborative Study of Neoplasia and Steroid Contraceptives (1989) Histologic types of breast carcinoma in relation to international variation and breast risk factors. Int J Cancer 44: 399-409
27. Stewart AJ, Westley BR, May FEB (1992) Modulation of the proliferative response of breast cancer cells to growth factors by oestrogen. Br J Cancer 66: 640-648
28. UK National Case Control Study Group (1989) Oral contraceptive use and breast cancer risk in young women. Lancet I: 973-982
29. WHO Collaborative Study of Neoplasia and Steroid Contraceptives (1990) Breast cancer and combined oral contraceptives: results from a multinational study. Br J Cancer 61: 110-119
30. Williams G, Anderson E, Howell A, Watson R, Coyne J, Roberts SA, Potten C (1991) Oral contraceptive (OCP) use increases proliferation and decreases oestrogen receptor content of epithelial cells in the normal human breast. Int J Cancer 48: 206-210