Betidamino acids: Versatile and constrained scaffolds for drug discovery

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 5, 1996, Pages 2031-2036

  Rivier, Jean E ^a   Jiang, Guangcheng ^a   Koerber, Steven C ^a   Porter, John ^a   Simon, Lajos ^b   Craig, A Grey ^a   Hoeger, Carl A ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b UNIVERSITY OF SZEGED   (Hungary)

Author keywords

aminoglycine; betides; chemical diversity; gonadotropin releasing hormone antagonists; N acyl and N alkylaminoglycine

Indexed keywords

ACETYL DEXTRO 3 (2 NAPHTHYL)ALANYL DEXTRO 4 CHLOROPHENYLALANYL DEXTRO 3 (3 PYRIDYL)ALANYLSERYL 4 ACETYLAMINOPHENYLALANYL DEXTRO 4 ACETYLAMINOPHENYLALANYLLEUCYL N EPSILON ISOPROPYLLYSYLPROLYL DEXTRO ALANINAMIDE; AMIDE; AMINO ACID DERIVATIVE; BETIDAMINO ACID; GLYCINE DERIVATIVE; GONADORELIN ANTAGONIST; UNCLASSIFIED DRUG;

ARTICLE; BIOCOMPATIBILITY; DRUG POTENCY; DRUG RESEARCH; DRUG STRUCTURE; DRUG SYNTHESIS; MOLECULAR MODEL; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

AMINO ACID SEQUENCE; ANIMALS; COMPUTER SIMULATION; DIAMINES; DRUG DESIGN; FEMALE; GLYCINE; GONADOTROPIN-RELEASING HORMONE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OVULATION; PEPTIDES; RATS;

EID: 0029882807     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.5.2031     Document Type: Article

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