Immunogenicity and protection studies with recombinant mycobacteria and vaccinia vectors coexpressing the 18-kilodalton protein of Mycobacterium leprae

Infection and Immunity

Volumn 64, Issue 6, 1996, Pages 2274-2281

  Baumgart, Karl W ^a   Mckenzie, Kirsten R ^a   Radford, Anthony J ^b   Ramshaw, Ian ^c   Britton, Warwick J ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b CSIRO   (Australia)

^c Biology and Environment   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; MYCOBACTERIUM ANTIGEN;

ANIMAL CELL; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; EXPRESSION VECTOR; FOOT PAD; IMMUNIZATION; IMMUNOGENICITY; LYMPHOCYTE PROLIFERATION; MOUSE; MYCOBACTERIOSIS; MYCOBACTERIUM BOVIS; MYCOBACTERIUM LEPRAE; NONHUMAN; PRIORITY JOURNAL; VACCINIA VIRUS;

EID: 0029882782     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.64.6.2274-2281.1996     Document Type: Article

References (37)

1. Aldovini, A., and R. A. Young. 1991. Humoral and cell-mediated immune responses to live recombinant BCG-HIV vaccines. Nature (London) 351: 479-482.
2. Booth, R. J., D. L. Williams, K. D. Moudgil, L. C. Noonan, P. M. Grandison, J. J. McKee, R. L. Prestidge, and J. D. Watson. 1993. Homologs of Mycobacterium leprae 18-kilodalton and Mycobacterium tuberculosis 19-kilodalton antigens in other mycobacteria. Infect. Immun. 61:1509-1515.
3. Boyle, D., B. Coupar, and G. Both. 1985. Multiple-cloning-site plasmids for the rapid construction of recombinant pox viruses. Gene 35:167-177.
4. Bretscher, P. A. 1992. A strategy to improve the efficacy of vaccination against tuberculosis and leprosy. Immunol. Today 13:342-345.
5. Britton, W. J., L. Hellqvist, A. Basten, and R. L. Raison. 1985. Mycobacterium leprae antigens involved in human murine responses. I. Identification of four antigens by monoclonal antibodies. J. Immunol. 135:4171-4177.
6. Cooney, E. L., M. J. McElrath, L. Corey, S. L. Hu, A. C. Collier, D. Arditti, M. Hoffman, R. W. Coombs, G. E. Smith, and P. D. Greenberg. 1993. Enhanced immunity to human immunodeficiency virus (HIV) envelope elicited by a combined vaccine regimen consisting of priming with a vaccinia recombinant expressing HIV envelope and boosting with gp160 protein. Proc. Natl. Acad. Sci. USA 90:1882-1886.
7. Davenport, M. P., K. R. McKenzie, A. Basten, and W. J. Britton. 1992. The variable C-terminal region of the Mycobacterium leprae 70-kilodalton heat shock protein is the target for humoral immune responses. Infect. Immun. 60:1170-1177.
8. Dockrell, H. M., N. G. Stoker, S. P. Lee, M. Jackson, K. A. Grant, N. F. Jouy, S. B. Lucas, R. Hasan, R. Hussain, and K. P. W. J. McAdam. 1989. T-cell recognition of the 18-kilodalton antigen of Mycobacterium leprae. Infect. Immun. 57:1979-1983.
9. Doherty, T. M., B. T. Backstrom, R. L. Prestidge, S. G. Love, D. R. K. Harding, and J. D. Watson. 1991. Immune responses to the 18-kDa protein of Mycobacterium leprae. Similar B cell epitopes but different T cell epitopes seen by inbred strains of mice. J. Immunol. 146:1934-1940.
10. Flesch, I. E., J. H. Hess, S. Huang, M. Aguet, J. Rothe, H. Bluethmann, and S. H. Kaufmann. 1995. Early interleukin-12 production by macrophages in response to mycobacterial infection depends on interferon-gamma and tumor necrosis factor-alpha. J. Exp. Med. 181:1615-1621.
11. Flynn, J. L., M. M. Goldstein, K. J. Triebold, B. Kooler, and B. R. Bloom. 1992. Major histocompatibility complex class I-restricted T cells are required for resistance to Mycobacterium tuberculosis infection. Proc. Natl. Acad. Sci. USA 89:12013-12017.
12. Gheorghiu, M., M. R. Lagranderie, B. M. E. Gicquel, and C. D. Leclerc. 1994. Mycobacterium bovis BCG priming induces a strong potentiation of the antibody response induced by recombinant BCG expressing a foreign antigen. Infect. Immun. 62:4287-4295.
13. Horwitz, M. A., B. W. E. Lee, B. J. Dillon, and G. Harth. 1995. Protective immunity against tuberculosis induced by vaccination with major extracellular proteins of Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. USA 92: 1530-1534.
14. Hu, S. L., K. Abrams, G. N. Barber, P. Moran, J. M. Zarling, A. J. Langlois, L. Kuller, W. R. Morton, and R. E. Benveniste. 1992. Protection of macaques against SIV infection by subunit vaccines of SIV envelope glycoprotein gp160. Science 255:456-459.
15. Huygen, K., K. Palfliet, F. Jurion, J. Hilgers, R. ten Berg, J.-P. Van Vooren, and J. De Bruyn. 1988. H-2-linked control of in vitro gamma interferon production in response to a 32-kilodalton antigen (P32) of Mycobacterium bovis bacillus Calmette-Guerin. Infect. Immun. 56:3196-3200.
16. Jacobs, W. R., Jr. 1992. Advances in mycobacterial genetics: new promises for old diseases. Immunobiology 184:147-156.
17. Kaufmann, S. H. E. 1991. Role of T-cell subsets in bacterial infections. Curr. Opin. Immunol. 3:465-470.
18. Kaufmann, S. H. E. 1994. Bacterial and protozoal infections in genetically disrupted mice. Curr. Opin. Immunol. 6:518-525.
19. Kohonen-Corish, M. R., N. J. King, C. E. Woodhams, and I. A. Ramshaw. 1990. Immunodeficient mice recover from infection with vaccinia. Eur. J. Immunol. 20:157-161.
20. Kolb, H., and V. Kolb-Bachnofen. 1992. Nitric oxide: a pathogenetic factor in autoimmunity. Immunol. Today 13:157-164.
21. Lamb, F. I., N. B. Singh, and M. J. Colston. 1990. The specific 18-kilodalton antigen of Mycobacterium leprae is present in Mycobacterium habana and functions as a heat-shock protein. J. Immunol. 144:1922-1925.
22. Langermann, S., S. R. Palaszynski, J. E. Burlein, S. Koenig, M. S. Hanson, D. E. Briles, and C. K. Stover. 1994. Protective humoral response against pneumococcal infection in mice elicited by recombinant Bacille Calmette-Guerin vaccines expressing pneumococcal surface protein A. J. Exp. Med. 180:2277-2286.
23. Leong, K. H., I. A. Ramshaw, and A. J. Ramsay. IL-7 enhances CTL and LAK activity in vivo in an IL-2 dependent manner. Submitted for publication.
24. Lowrie, D. B., M. J. Colston, and R. E. Tascou. 1995. Protection against tuberculosis by immunisation of mice by intra-muscular injection of naked DNA expressing M. leprae HSP65. J. Clin. Biochem. Suppl. 19B:413.
25. Lyons, J., C. Sinos, A. Destree, T. Caiazzo, K. Havican, S. McKenzie, D. Panicali, and A. Mahr. 1990. Expression of Mycobacterium tuberculosis and Mycobacterium leprae proteins by vaccinia virus. Infect. Immun. 58:4089-4098.
26. Mackett, M., and G. Smith. 1986. Vaccinia virus expression vectors. J. Gen. Virol. 67:2067-2082.
27. Mosier, D. E., R. J. Gulizia, P. D. MacIsaac, L. Corey, and P. D. Greenberg. 1993. Resistance to human immunodeficiency virus 1 infection of SCID mice reconstituted with peripheral blood leukocytes from donors vaccinated with vaccinia gp160 and recombinant gp160. Proc. Natl. Acad. Sci. USA 90:2443-2447.
28. Mosmann, T. R., and R. L. Coffman. 1989. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7:145-173.
29. Moss, B., and C. Flexner. 1992. Vaccinia virus expression vectors. Annu. Rev. Immunol. 5:305-324.
30. Murray, A., N. Winter, M. Lagranderie, D. F. Hill, J. Rauzier, J. Timm, C. Ledere, K. M. Moriarty, M. Gheorghiu, and B. Gicquel. 1992. Expression of Escherichia coli beta-galactosidase in Mycobacterium bovis BCG using an expression system isolated from Mycobacterium paratuberculosis which induced humoral and cellular immune responses. Mol. Microbiol. 6:3331-3342.
31. Orme, I. M. 1988. Evidence for a biphasic memory T-cell response to high dose BCG vaccination in mice. Tubercle 69:125-131.
32. Ramshaw, I., J. Ruby, G. Karupiah, G. Ada, and A. Ramsay. 1992. Expression of cytokines by recombinant vaccinia viruses: a model for studying cytokines in virus infections in vivo. Immunol. Rev. 127:157-182.
33. Roche, P. Personal communication.
34. Silva, C. L., and D. B. Lowrie. 1994. A single mycobacterial protein (hsp65) expressed by a transgenic antigen-presenting cell vaccinates mice against tuberculosis. Immunology 82:244-248.
35. Silva, C. L., M. F. Silva, R. C. L. R. Pietro, and D. B. Lowrie. 1994. Protection against tuberculosis by passive transfer with T-cell clones recognizing mycobacterial heat-shock protein 65. Immunology 83:341-346.
36. Stover, C. K., G. P. Bansal, M. S. Hanson, J. E. Burlein, S. R. Palaszynski, J. F. Young, S. Koenig, D. B. Young, A. Sadziene, and A. G. Barbour. 1993. Protective immunity elicited by recombinant Bacille Calmette-Guerin (BCG) expressing outer surface protein A (OspA) lipoprotein: a candidate Lyme disease vaccine. J. Exp. Med. 178:197-209.
37. Stover, C. K., V. F. de la Cruz, T. R. Fuerst, J. E. Burlein, L. A. Benson, L. T. Bennett, G. P. Bansal, J. F. Young, M. H. Lee, and G. F. Hatfull. 1991. New use of BCG for recombinant vaccines. Nature (London) 351:456-460.