Intramyocardial injections and protection against myocardial ischemia: An attempt to examine the cardioprotective actions of adenosine

Circulation

Volumn 93, Issue 11, 1996, Pages 2043-2051

  Whittaker, Peter ^a,b   Kloner, Robert A ^a   Przyklenk, Karin ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b GOOD SAMARITAN HOSPITAL   (United States)

Author keywords

Adenosine; arrhythmia; gadolinium; myocardial infarction; signal transduction

Indexed keywords

ADENOSINE; GADOLINIUM CHLORIDE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOG; ELECTROCARDIOGRAM; EXTRASYSTOLE; FEMALE; HEART INFARCTION; HEART INFARCTION SIZE; HEART MUSCLE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HEART VENTRICLE TACHYCARDIA; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; STRETCHING;

EID: 0029882774     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.93.11.2043     Document Type: Article

References (35)

1. Downey JM, Liu GS, Thornton JD. Adenosine and the anti-infarct effects of preconditioning. Cardiovasc Res. 1993;27:3-8.
2. Toombs CF, McGee DS, Johnston WE, Vinten-Johansen J. Myocardial protective effects of adenosine: infarct size reduction with pretreatment and continued receptor stimulation during ischemia. Circulation. 1992;86:986-994.
3. Randhawa MPS Jr, Lasley RD, Mentzer RM Jr. Salutary effects of exogenous adenosine administration on in vivo myocardial stunning. J Thorac Cardiovasc Surg. 1995;110:63-74.
4. ATP channels. Circulation. 1994;89:1229-1236.
5. Li Y, Kloner RA. The cardioprotective effects of ischemic 'preconditioning' are not mediated by adenosine receptors in rat hearts. Circulation. 1993;87:1642-1648.
6. 1 adenosine receptors in rabbit heart. Circulation. 1991;84:350-356.
7. 1 receptor agonist, R(-)-N-(2-phenylisopropyl)-adenosine (PIA), but not adenosine itself, acts as a therapeutic preconditioning-mimetic agent in rabbits. Cardiovaac Res. 1993;27:2140-2145.
8. Schrader J. Formation and metabolism of adenosine and adenine nucleotides in cardiac tissue. In: Phillis JW, ed. Adenosine and Adenine Nucleotides as Regulators of Cellular Function. Boca Raton, Fla: CRC Press; 1991:55-69.
9. Himori N, Matsuura A. A simple technique for occlusion and reperfusion of coronary artery in conscious rats. Am J Physiol. 1989; 256:H1719-H1725.
10. Domenech RJ, Hoffman JE, Noble MM, Saunders KB, Henson RJ, Subyanto S. Total and regional coronary blood flow measured by radioactive microspheres in conscious and anesthetized dogs. Circ Res. 1969;23:581-596.
11. Ovize M, Przyklenk K, Kloner RA. Stretch preconditions the canine myocardium. Am J Physiol. 1994;266:H137-H146.
12. Przyklenk K, Sussman MA, Simkhovich BZ, Kloner RA. Does ischemic preconditioning trigger translocation of protein kinase C in the canine model? Circulation. 1995;92:1546-1557.
13. Whittaker P, Rakusan K, Kloner RA. Transmural channels can protect ischemic tissue: assessment of long-term myocardial response to laser- and needle-made channels. Circulation. 1996;93: 143-152.
14. Bankwala Z, Hale SL, Kloner RA. α-Adrenoceptor stimulation with exogenous norepinephrine or release of endogenous catechotamines mimics ischemic preconditioning. Circulation. 1994;90:1023-1028.
15. Van Wylen DGL, Willis J, Sodhi J, Weiss RJ, Lasley RD, Mentzer RM Jr. Cardiac microdialysis to estimate interstitial adenosine and coronary blood flow. Am J Physiol. 1990;258:H1642-H1649.
16. Knowlton AA. The role of heat shock proteins in the heart. J Mol Cell Cardiol. 1995;27:121-131.
17. Chien GL, Wolff RA, Davis RF, Van Winkle DM. 'Normothermic range' temperature affects myocardial infarct size. Cardiovasc Res. 1994;28:1014-1017.
18. Gambassi G, Cerbai E, Pahor M, Capogrossi MC, Carbonin P, Mugelli A. Temperature modulates calcium homeostasis and ventricular arrhythmias in myocardial preparations. Cardiovasc Res. 1994;28:391-399.
19. Warner KG, Khuri SF, Marston W, Sharma S, Butler MD, Assousa SN, Saad AJ, Siouffi ST, Lavin PT. Significance of the transmural diminution in regional hydrogen ion production after repeated coronary artery occlusions. Circ Res. 1989;64:616-628.
20. Whittaker P, Przyklenk K. Reduction of infarct size in vivo with ischemic preconditioning: mathematical evidence for protection via non-ischemic tissue. Basic Res Cardiol. 1994;89:6-15.
21. Przyklenk K, Bauer B, Ovize M, Kloner RA, Whittaker P. Regional ischemic 'preconditioning' protects remote virgin myocardium from subsequent sustained coronary artery occlusion. Circulation. 1993; 87:893-899.
22. Yang XC, Sachs F. Block of stretch-activated ion channels in xenopus oocytes by gadolinium and calcium ions. Science. 1989;243: 1068-1071.
23. Hansen DE, Borganelli M, Stacy GP Jr, Taylor LK. Dose-dependent inhibition of stretch-induced arrhythmias by gadolinium in isolated canine ventricle: evidence for a unique mode of antiarrhythmic action. Circ Res. 1991;69:820-831.
24. Knowlton AA, Eberli FR, Brecher P, Romo GM, Owen A, Apstein CS. A single myocardial stretch or decreased systolic fiber shortening stimulates the expression of heat shock protein 70 in the isolated, erythrocyte-perfused rabbit heart. J Clin Invest. 1991;88: 2018-2025.
25. Downey JM, Liu Y, Ytrehus K. Adenosine and the antiinfarct effects of preconditioning. In: Przyklenk K, Kloner RA, Yellon DM, eds. Ischemic Preconditioning: The Concept of Endogenous Protection. Boston, Mass: Kluwer Academic Publishers; 1993: 137-152.
26. Nees S, Herzog V, Becker BF, Bock M, Des Rosiers C, Gerlach E. The coronary endothelium: a highly active metabolic barrier for adenosine. Basic Res Cardiol. 1985;80:515-529.
27. Silva PH, Dillon D, Van Wylen DGL. Adenosine deaminase inhibition augments interstitial adenosine but does not attenuate myocardial infarction. Cardiovasc Res. 1995;29:616-623.
28. Lasley RD, Konyn PJ, Hegge JO, Mentzer RM Jr. Effects of ischemic and adenosine preconditioning on interstitial fluid adenosine and myocardial infarct size. Am J Physiol. 1995;269: H1460-H1466.
29. Fagbemi O, Parratt JR. Antiarrhythmic actions of adenosine in the early stages of experimental myocardial ischemia. Eur J Pharmacol. 1984;100:243-244.
30. Wainwright CL, Parratt JR. An antiarrhythmic effect of adenosine during myocardial ischaemia and reperfusion. Eur J Pharmacol. 1988;145:183-194.
31. Boachie-Ansah G, Kane KA, Parratt JR. Is adenosine an endogenous myocardial protective (antiarrhythmic) substance under conditions of ischemia? Cardiovasc Res. 1993;27:77-83.
32. Belardinelli L, Shryock JC, Song Y, Wang D, Srinivas M. Ionic basis of the electrophysiological actions of adenosine on cardiomyocytes. FASEB J. 1995;9:359-365.
33. Lerman BB, Belardinelli L. Cardiac electrophysiology of adenosine: basic and clinical concepts. Circulation. 1991;83:1499-1509.
34. Przyklenk K, Ovize M, Bauer B, Kloner RA. Gender does not influence acute myocardial infarction in adult dogs. Am Heart J. 1995;129:1108-1113.
35. Li Y, Kloner RA. Is there a gender difference in infarct size and arrhythmias following experimental coronary occlusion and reperfusion? J Thromb Thrombol. 1995;2:221-225.