Interferon gamma production in whole peripheral blood culture in acute hepatitis B

Scandinavian Journal of Clinical and Laboratory Investigation

Volumn 56, Issue 2, 1996, Pages 145-150

  Osna, N ^a   Duk, A ^b   Sochnev, A ^a  

^a RIGA STRADINS UNIVERSITY   (Latvia)

^b Latvian Natl Ctr of Public Health   (Latvia)

Author keywords

cell culture; HBV infection; interferon gamma induction; serum blocking factor

Indexed keywords

BILIRUBIN; GAMMA INTERFERON; PHYTOHEMAGGLUTININ;

ACUTE HEPATITIS; ARTICLE; BLOOD ANALYSIS; CELL CULTURE; CLINICAL ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; ERYTHROCYTE; HEPATITIS A; HEPATITIS B; HUMAN; HUMAN CELL; HUMAN TISSUE; MONONUCLEAR CELL; PRIORITY JOURNAL;

HEPATITIS B VIRUS;

EID: 0029882049     PISSN: 00365513     EISSN: None     Source Type: Journal    
DOI: 10.3109/00365519609088601     Document Type: Article

References (21)

1. Mieli-Vergani G, Vergani D, Portman B, White J, Lyon J, Murray-Lyon J, et al. Lymphocyte cytotoxicity to autologous hepatocytes in HBsAg-positive chronic liver disease. Gut 1982; 23: 1029-36.
2. Mondelli M, Eddleston A. Lymphocyte cytotoxicity for autologous hepatocytes. Gut 1984; 25: 109-13.
3. Arao M, Kakumu Sh, Tanara H, Yoshioka K. Interferon a- and g-positive mononuclear cells and HLA antigen expression in hepatocyte membrane in the liver in chronic type B and nonA-nonB hepatitis. Gastroenterol Jpn 1989; 24: 255-61.
4. Hu K.-Q, Yu C-H, Vierling JM. Up-regulation of intracellular adhesion molecule 1 transcription by hepatitis B virus X protein. Proc Natl Acad Sci USA 1992; 89: 11441-5.
5. Dalton DK, Pitts-Meek SH, Keshav S, Figari IS, Bradley A, Stewart TA. Multiple defects of immune function in mice with disrupted interferon g-gene. Science 1993; 259: 1739-42.
6. Ando K, Moriyama T, Guidotti LG, Wirth S, Scheiber RD, Schlicht HJ, et al. Mechanisms of class 1 restricted immunopathology. A transgenic mouse model of fulminant hepatitis. J Exp Med 1993; 178: 1541-54.
7. Hussain MJ, Mustafa A, Gallati H, Mowat AP, Mieli-Vergani G, Vergani D. Cellular expression of tumor necrosis factor-a and interferon-g in the liver biopsies of children with chronic liver disease. J Hepatol 1994; 21: 816-22.
8. Kirchner H, Kleinicke C, Digel W. A whole blood technique for testing production of human interferon by leukocytes. J Immunol Meth 1982; 48: 213-19.
9. De Groote D, Zangerle PF, Gevaert Y, Fassotte MF, Beguin Y, Noizat-Pienne F, et al. Direct stimulation of cytokines (IL-1B, TNFa, IL-6, IL-2, IFNg and CM-CSF) in whole blood. 1. Comparison with isolated PBMC stimulation. Cytokine 1992; 4: 239-48.
10. Sandvig S, Laskay T, Anderson J, De Ley M, Anderson U. Gamma-interferon is produced by CD3+ and CD3- lymphocytes. Immunol Rev 1987; 97: 51-65.
11. Wakita T, Kakumu S, Voshioka K, Ishikawa T, Ito V, Shinagawa T. Cellular immune responses of peripheral blood mononuclears to HBV antigens during chronic and acute HBV infection. Digestion 1992; 52: 26-33.
12. Gold KM, Weyland CM, Goronzy JF. Modulation of helper T1 cell function by prostaglandins. Arthritis Rheum. 1994; 37; 925-33.
13. Howard M, O'Garra. Biological properties of IL-10. Immunol Today 1992; 13: 198-200.
14. Ross C, Hansen MB, Schyberg T, Berg K. Autoantibodies to crude human leukocyte interferon (IFN), native human IFN, recombinant human IFN-alpha, recombinant human IFN-alpha 2b and human IFN-gamma in healthy blood donors. Clin Exp Immunol 1990; 82: 56-7.
15. Lau JY, Morris AG, Alexander GJ, Williams R. Interferon gamma receptor expression in chronic hepatitis B virus infection. J Hepatol 1992; 14: 294-9.
16. Valente G, Ozmen L, Noveli F, Palestro G, Forni G, Garotta G. Distribution of IFNg receptors in human tissue. J Interfer Res 1991; 11: 209.
17. Parronchi P, Carli MD, Manetti R, Simonelli C, Sampognaro S, Piccini M-P, et al. IL-4 and IFNa and -g exert opposite regulatory effects on the development of cytolytic potential by Th1 or Th2 human cell clones. J Immunol 1992; 149: 2957-63.
18. Alberti A. Pathobiology of hepatitis B virus infection and mechanism of action of interferon. Progress in Hepatology 93; 1993; Paris. European Association for the Study of the Liver.
19. Foster GR, Goldin RD, Thomas HC, Stark GR. Expression of the hepatitis B virus polymerase is associated with failure to respond to interferon therapy. J Interfer Res 1991; 11: 124.
20. Carreno V, Moreno A, Galiana F, Bartolome F. Alpha- and gamma-interferon versus alpha interferon alone in chronic hepatitis B. A randomized controlled study. J Hepatol 1993; 17: 321-5.
21. Kakumu S, Ishikawa T, Wakita T, Yoshioka K, Takayanagi M, Tahara H, et al. Interferon-gamma production specific for hepatitis B virus antigen by intrahepatic T lymphocytes in patients with acute and chronic hepatitis B. Am J Gastroenterol 1994; 89: 92-6.