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Volumn 11, Issue 2, 1996, Pages 183-190

The pathogenesis of cardiac allograft vasculopathy

Author keywords

[No Author keywords available]

Indexed keywords

CELL RECEPTOR; ENDOTHELIN; GROWTH FACTOR; IMMUNOSUPPRESSIVE AGENT; LIPOPROTEIN; PROTEOGLYCAN; RAPAMYCIN; TACROLIMUS;

EID: 0029881421     PISSN: 02684705     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001573-199603000-00012     Document Type: Review
Times cited : (36)

References (54)
  • 1
    • 0023201174 scopus 로고
    • Cardiac transplant atherosclerosis
    • Billingham ME: Cardiac transplant atherosclerosis. Transplant Proc 1987, 19(4 suppl 5):19-25.
    • (1987) Transplant Proc , vol.19 , Issue.4 SUPPL. 5 , pp. 19-25
    • Billingham, M.E.1
  • 2
    • 0023617374 scopus 로고
    • Clinical and laboratory correlates of accelerated coronary artery disease in the cardiac transplant patient
    • Gao SZ, Schroeder JS, Alderman EL, Hunt SA, Silverman JF: Clinical and laboratory correlates of accelerated coronary artery disease in the cardiac transplant patient. Circulation 1987, 76(suppl V):V-56-V-61.
    • (1987) Circulation , vol.76 , Issue.5 SUPPL.
    • Gao, S.Z.1    Schroeder, J.S.2    Alderman, E.L.3    Hunt, S.A.4    Silverman, J.F.5
  • 3
    • 0023696584 scopus 로고
    • Accelerated coronary vascular disease in the heart transplant patient: Coronary arteriographic findings
    • Gao SZ, Alderman EL, Schroeder JS, Silverman JF, Hunt SA: Accelerated coronary vascular disease in the heart transplant patient: coronary arteriographic findings. J Am Coll Cardiol 1988, 12:334-340.
    • (1988) J Am Coll Cardiol , vol.12 , pp. 334-340
    • Gao, S.Z.1    Alderman, E.L.2    Schroeder, J.S.3    Silverman, J.F.4    Hunt, S.A.5
  • 4
    • 0028099946 scopus 로고
    • Posttransplant coronary artery disease in children: A multicenter national survey
    • Pahl E, Zales VR, Fricker J, Addonizio LJ: Posttransplant coronary artery disease in children: a multicenter national survey. Circulation 1994, 90(part 2):II-56-II-60.
    • (1994) Circulation , vol.90 , Issue.2 PART
    • Pahl, E.1    Zales, V.R.2    Fricker, J.3    Addonizio, L.J.4
  • 5
    • 0028942660 scopus 로고
    • An intravascular ultrasound study of the influence of angiotensin-converting enzyme inhibitors and calcium entry blockers on the development of cardiac allograft vasculopathy
    • Mehra MR, Ventura HO, Smart FW, Collins TJ, Ramee SR, Stapleton DD: An intravascular ultrasound study of the influence of angiotensin-converting enzyme inhibitors and calcium entry blockers on the development of cardiac allograft vasculopathy. Am J Cardiol 1995, 75:853-854.
    • (1995) Am J Cardiol , vol.75 , pp. 853-854
    • Mehra, M.R.1    Ventura, H.O.2    Smart, F.W.3    Collins, T.J.4    Ramee, S.R.5    Stapleton, D.D.6
  • 6
    • 0028080355 scopus 로고
    • Ultrafast computed tomographic scanning for detection of coronary disease in cardiac transplant recipients
    • Barbir M, Bowker T, Ludman PF, Mitchell AG, Wood D, Yacoub M: Ultrafast computed tomographic scanning for detection of coronary disease in cardiac transplant recipients. Am J Cardiol 1994, 74:941-944.
    • (1994) Am J Cardiol , vol.74 , pp. 941-944
    • Barbir, M.1    Bowker, T.2    Ludman, P.F.3    Mitchell, A.G.4    Wood, D.5    Yacoub, M.6
  • 8
    • 0028088375 scopus 로고
    • Comparable proximal and distal severity of intimal thickening and size of epicardial coronary arteries in transplant arteriopathy of human cardiac allografts
    • Lin H, Wilson JE, Kendall TJ, Rardio SJ, Cornhill FJ, Herderick E, Winters GL, Costanso MR, Porter T, Thieszen SL, McManus BM: Comparable proximal and distal severity of intimal thickening and size of epicardial coronary arteries in transplant arteriopathy of human cardiac allografts. J Heart Lung Transplant 1994, 13:824-833. Describes in great detail the distinct morphology of CAV, which involves the comparable severity of intimal thickening of proximal and distal epicardial coronary arteries in human cardiac aloografts using autopsy tissues.
    • (1994) J Heart Lung Transplant , vol.13 , pp. 824-833
    • Lin, H.1    Wilson, J.E.2    Kendall, T.J.3    Rardio, S.J.4    Cornhill, F.J.5    Herderick, E.6    Winters, G.L.7    Costanso, M.R.8    Porter, T.9    Thieszen, S.L.10    McManus, B.M.11
  • 9
    • 0027192259 scopus 로고
    • Atherosclerosis: Current understanding of mechanisms and future strategies in therapy
    • Ross R: Atherosclerosis: current understanding of mechanisms and future strategies in therapy [review]. Transplant Proc 1993, 25:2041-2043.
    • (1993) Transplant Proc , vol.25 , pp. 2041-2043
    • Ross, R.1
  • 10
    • 0026526490 scopus 로고
    • Cytokines and growth factors in atherogenesis
    • Clinton SK, Libby P: Cytokines and growth factors in atherogenesis [review]. Arch Pathol Lab Med 1992, 116:1292-1300.
    • (1992) Arch Pathol Lab Med , vol.116 , pp. 1292-1300
    • Clinton, S.K.1    Libby, P.2
  • 11
    • 0023927488 scopus 로고
    • Production of platelet-derived growth factor-like mitogen by smooth-muscle cells from human atheroma
    • Libby P, Warner SJC, Solomon RN : Production of platelet-derived growth factor-like mitogen by smooth-muscle cells from human atheroma. N Engl J Med 1988, 318:1493-1498.
    • (1988) N Engl J Med , vol.318 , pp. 1493-1498
    • Libby, P.1    Warner, S.J.C.2    Solomon, R.N.3
  • 13
    • 0027425652 scopus 로고
    • The expression of acidic fibroblast growth factor (heparin binding growth 1) and cytokine genes in human cardiac allografts and T cells
    • Zhao XM, Yeoh TK, Hiebert M, Frist H, Miller GG: The expression of acidic fibroblast growth factor (heparin binding growth 1) and cytokine genes in human cardiac allografts and T cells. Transplantation 1993, 56:1177-1182.
    • (1993) Transplantation , vol.56 , pp. 1177-1182
    • Zhao, X.M.1    Yeoh, T.K.2    Hiebert, M.3    Frist, H.4    Miller, G.G.5
  • 14
    • 0027201103 scopus 로고
    • Expression of cytokine genes in human cardiac allografts correlation of IL-6 and TGF-beta with histological rejection
    • Zhao XM, Frist WH, Yeoh TK, Miller GG : Expression of cytokine genes in human cardiac allografts correlation of IL-6 and TGF-beta with histological rejection. Clin Exp Immunol 1993, 93:448-451.
    • (1993) Clin Exp Immunol , vol.93 , pp. 448-451
    • Zhao, X.M.1    Frist, W.H.2    Yeoh, T.K.3    Miller, G.G.4
  • 16
    • 0026778151 scopus 로고
    • Lymphocytic subsets and histopathologic changes associated with the development of heart transplant arteriosclerosis
    • Cramer DV, Wu GD, Chapman FA, Cajulis E, Wang HK, Makowka L: Lymphocytic subsets and histopathologic changes associated with the development of heart transplant arteriosclerosis. J Heart Lung Transplant 1992, 11:458-466.
    • (1992) J Heart Lung Transplant , vol.11 , pp. 458-466
    • Cramer, D.V.1    Wu, G.D.2    Chapman, F.A.3    Cajulis, E.4    Wang, H.K.5    Makowka, L.6
  • 17
    • 0027365067 scopus 로고
    • Experimental graft arteriosclerosis: Part II. Immunocytochemical analysis of lesion development
    • Adams DH, Wyner LR, Karnovsky MJ: Experimental graft arteriosclerosis: Part II. Immunocytochemical analysis of lesion development. Transplantation 1993, 56:794-799.
    • (1993) Transplantation , vol.56 , pp. 794-799
    • Adams, D.H.1    Wyner, L.R.2    Karnovsky, M.J.3
  • 19
    • 0028101391 scopus 로고
    • Modification of alternative messenger RNA splicing of fibroblast growth factor receptors in human cardiac allografts during rejection
    • Zhao XM, Frist WH, Yeoh TK, Miller GG: Modification of alternative messenger RNA splicing of fibroblast growth factor receptors in human cardiac allografts during rejection. J Clin Invest 1994, 94:992-1003. Describes in detail the expression of messenger RNA encoding different domains of aFG receptors in cardiac allograft rejection, the relationship of this expression with cytokines, and the potential role of this expression in CAV.
    • (1994) J Clin Invest , vol.94 , pp. 992-1003
    • Zhao, X.M.1    Frist, W.H.2    Yeoh, T.K.3    Miller, G.G.4
  • 21
    • 0001185590 scopus 로고
    • Endothelin, a potent vasoconstrictor, is a vascular smooth muscle mitogen
    • Dubin D, Pratt RE, Cooke JP, Dzau VJ: Endothelin, a potent vasoconstrictor, is a vascular smooth muscle mitogen. J Vasc Med Biol 1989, 1:150-154.
    • (1989) J Vasc Med Biol , vol.1 , pp. 150-154
    • Dubin, D.1    Pratt, R.E.2    Cooke, J.P.3    Dzau, V.J.4
  • 22
    • 0028300301 scopus 로고
    • The emerging concept of vascular remodeling
    • Gibbons gh, Dzau VJ: The emerging concept of vascular remodeling. N Engl J Med 1994, 330:1431-1438.
    • (1994) N Engl J Med , vol.330 , pp. 1431-1438
    • Gibbons, G.H.1    Dzau, V.J.2
  • 23
    • 0029053217 scopus 로고
    • Up-regulation of endothelin-1 mRNA and peptide expression in rat cardiac allografts with rejection and arteriosclerosis
    • Watschinger B, Sayegh MH, Hancock WW, Russell ME: Up-regulation of endothelin-1 mRNA and peptide expression in rat cardiac allografts with rejection and arteriosclerosis. Am J Pathol 1995, 146:1065-1072.
    • (1995) Am J Pathol , vol.146 , pp. 1065-1072
    • Watschinger, B.1    Sayegh, M.H.2    Hancock, W.W.3    Russell, M.E.4
  • 24
    • 0029016688 scopus 로고
    • Plasma endothelin and early coronary endothelial dysfunction in recipients of a cardiac transplant
    • Berkenboom G, Giot C, Unger P, Vachiery JL, Antoine M, LeClerc JL: Plasma endothelin and early coronary endothelial dysfunction in recipients of a cardiac transplant. Am Heart J 1994, 129:1178-1184.
    • (1994) Am Heart J , vol.129 , pp. 1178-1184
    • Berkenboom, G.1    Giot, C.2    Unger, P.3    Vachiery, J.L.4    Antoine, M.5    LeClerc, J.L.6
  • 26
    • 0029058275 scopus 로고
    • Early impairment of acetylcholine-induced endothelium-dependent coronary vasodilation is not predictive of secondary graft atherosclerosis
    • Aptecar E, Benvenuti C, Loisance D, Cachera JP, Nitenberg A: Early impairment of acetylcholine-induced endothelium-dependent coronary vasodilation is not predictive of secondary graft atherosclerosis. Chest 1995, 107:1266-1274.
    • (1995) Chest , vol.107 , pp. 1266-1274
    • Aptecar, E.1    Benvenuti, C.2    Loisance, D.3    Cachera, J.P.4    Nitenberg, A.5
  • 28
    • 0028913285 scopus 로고
    • Cardiac allograft vascular disease: Relationship to microvascular cell surface markers and inflammatory cell phenotypes on endomyocardial biopsy
    • Deng MC, Bell S, Huie P, Pinto F, Hunt SA, Stinson EB, Sibley R, Hall BM, Valantine HA: Cardiac allograft vascular disease: relationship to microvascular cell surface markers and inflammatory cell phenotypes on endomyocardial biopsy. Circulation 1995, 91:1647-1654.
    • (1995) Circulation , vol.91 , pp. 1647-1654
    • Deng, M.C.1    Bell, S.2    Huie, P.3    Pinto, F.4    Hunt, S.A.5    Stinson, E.B.6    Sibley, R.7    Hall, B.M.8    Valantine, H.A.9
  • 31
    • 0027937745 scopus 로고
    • Cytolytic T-cell cytotoxicity is mediated through perform and Fas lytic pathways
    • Lowin B, Hahe M, Mattmann C, Tschopp J: Cytolytic T-cell cytotoxicity is mediated through perform and Fas lytic pathways. Nature 1994, 370:650-652. Clearly demonstrates that cytotoxicity imparted by cytolytic T cells is exclusively mediated by perform- and Fas-based lytic pathways by in vitro work.
    • (1994) Nature , vol.370 , pp. 650-652
    • Lowin, B.1    Hahe, M.2    Mattmann, C.3    Tschopp, J.4
  • 32
    • 0028110928 scopus 로고
    • Fas and perforin pathways as major mechanisms of T-cell-mediated cytotoxicity
    • Kagi D, Vignaux F, Ledermann B, Burki K, Depraetere V, Nagata S, Hengartner H, Goldstein P: Fas and perforin pathways as major mechanisms of T-cell-mediated cytotoxicity. Science 1994, 265:528-530. Clearly demonstrates that cytotoxicity imparted by cytolytic T cells is exclusively mediated by perforin- and Fas-based lytic pathways by in vitro work.
    • (1994) Science , vol.265 , pp. 528-530
    • Kagi, D.1    Vignaux, F.2    Ledermann, B.3    Burki, K.4    Depraetere, V.5    Nagata, S.6    Hengartner, H.7    Goldstein, P.8
  • 33
    • 0029881386 scopus 로고    scopus 로고
    • Human transplant coronary artery disease: Pathological evidence for fas-mediated apoptotic cytotoxicity in allograft arteriopathy
    • in press
    • Dong C, Wilson JE, Winters GL, McManus BM: Human transplant coronary artery disease: pathological evidence for fas-mediated apoptotic cytotoxicity in allograft arteriopathy. Lab Invest 1996, in press. The first paper describing apoptosis and its pathway in transplantation CAV. The authors also describe the different form of cell death seen in native coronary artery disease and the potential relevance to the different morphology and development of transplantation coronary artery disease and native coronary artery disease.
    • (1996) Lab Invest
    • Dong, C.1    Wilson, J.E.2    Winters, G.L.3    McManus, B.M.4
  • 34
    • 0028328488 scopus 로고
    • Fas antigen is the major target molecule for CD4+ T cell-mediated cytotoxicity
    • Stalder T, Hahn S, Erb P: Fas antigen is the major target molecule for CD4+ T cell-mediated cytotoxicity. J Immunol 1994, 152:1127-1133.
    • (1994) J Immunol , vol.152 , pp. 1127-1133
    • Stalder, T.1    Hahn, S.2    Erb, P.3
  • 37
    • 0027985417 scopus 로고
    • Comparison of the effectiveness of Lovastatin therapy for hypercholesterolemia after heart transplantation between patients with and without pretransplant atherosclerotic coronary artery disease
    • Anguita M, Alonso-Pulpon L, Arizon JM, Cavero MA, Valles F, Segovia J, Perez-Jimenez,F Crespo M, Concha M: Comparison of the effectiveness of Lovastatin therapy for hypercholesterolemia after heart transplantation between patients with and without pretransplant atherosclerotic coronary artery disease. Am J Cardiol 1994, 74:776-779.
    • (1994) Am J Cardiol , vol.74 , pp. 776-779
    • Anguita, M.1    Alonso-Pulpon, L.2    Arizon, J.M.3    Cavero, M.A.4    Valles, F.5    Segovia, J.6    Perez-Jimenez, F.7    Crespo, M.8    Concha, M.9
  • 39
    • 9344243028 scopus 로고
    • Biglycan, decorin and versican protein expression patterns in coronary arteriopathy of human heart allografts: Distinctness as compared to native atherosclerosis
    • in press
    • Lin H, Wilson JE, Roberts CR, Horley KJ, Winter GL, Costanzo MR, McManus BM: Biglycan, decorin and versican protein expression patterns in coronary arteriopathy of human heart allografts: distinctness as compared to native atherosclerosis. J Heart Lung Transplant 1995, in press. The first paper to describe biglycan, decorin, and versican expression using immunohistochemistry in CAV and native atherosclerosis as well as in normal coronary arteries.
    • (1995) J Heart Lung Transplant
    • Lin, H.1    Wilson, J.E.2    Roberts, C.R.3    Horley, K.J.4    Winter, G.L.5    Costanzo, M.R.6    McManus, B.M.7
  • 40
    • 9344243597 scopus 로고
    • Prominence of apolipoproteins B, (a) and E in the intimae of coronary arteries in transplanted human hearts: Geographical relationship to vessel wall proteoglycans
    • in press
    • Lin H, Ignatescu M, Wilson JE, Roberts CR, Horley KJ, Winters GL, Costanzo MR, McManus BM: Prominence of apolipoproteins B, (a) and E in the intimae of coronary arteries in transplanted human hearts: geographical relationship to vessel wall proteoglycans. J Heart Lung Transplant 1995, in press. Details distribution of apoplipoproteins in CAV and the relationship of CAV with proteoglycans. The authors also discuss the potential role of apolipoproteins in CAV.
    • (1995) J Heart Lung Transplant
    • Lin, H.1    Ignatescu, M.2    Wilson, J.E.3    Roberts, C.R.4    Horley, K.J.5    Winters, G.L.6    Costanzo, M.R.7    McManus, B.M.8
  • 41
    • 0028944150 scopus 로고
    • Prevention of atherosclerosis in apolipoprotein E-deficient mice by bone marrow transplantation
    • Linton MF, Atkinson JB, Fazio S: Prevention of atherosclerosis in apolipoprotein E-deficient mice by bone marrow transplantation. Science 1995, 267:1034-1037. This meticulous work, using apolipoprotein E-deficient mice, clearly demonstrates that apolipoprotein E can prevent atherosclerosis.
    • (1995) Science , vol.267 , pp. 1034-1037
    • Linton, M.F.1    Atkinson, J.B.2    Fazio, S.3
  • 42
    • 0028033418 scopus 로고
    • Potential role of human cytomegalovirus and p53 interaction in coronary restenosis
    • Speir E, Modali R, Huang E-S, Leon MB, Shawl F, Finkel T, Epstein SE: Potential role of human cytomegalovirus and p53 interaction in coronary restenosis. Science 1994, 265:391-394. Demonstrates for the first time that tumor supressor gene p53 and human cytomegalovirus are linked to coronary restenosis.
    • (1994) Science , vol.265 , pp. 391-394
    • Speir, E.1    Modali, R.2    Huang, E.-S.3    Leon, M.B.4    Shawl, F.5    Finkel, T.6    Epstein, S.E.7
  • 43
    • 0024379937 scopus 로고
    • Association of coronary artery disease in cardiac transplant recipients with cytomegalovirus infection
    • McDonald K, Rector TS, Braunlin EA, Kubo SH, Olivari MT: Association of coronary artery disease in cardiac transplant recipients with cytomegalovirus infection. Am J Cardiol 1989, 64:359-362.
    • (1989) Am J Cardiol , vol.64 , pp. 359-362
    • McDonald, K.1    Rector, T.S.2    Braunlin, E.A.3    Kubo, S.H.4    Olivari, M.T.5
  • 44
    • 0028170637 scopus 로고
    • Cytomegalovirus infection enhances mRNA expression of platelet-derived growth factor-BB and transforming growth factor-B1 in rat aortic allografts: Possible mechanism for cytomegalovirus-enhanced graft arteriosclerosis
    • Lemstrom KB, Aho PT, Bruggeman CA, Hayry PJ: Cytomegalovirus infection enhances mRNA expression of platelet-derived growth factor-BB and transforming growth factor-B1 in rat aortic allografts: possible mechanism for cytomegalovirus-enhanced graft arteriosclerosis. Arterioscler Thromb 1994, 14:2043-2052.
    • (1994) Arterioscler Thromb , vol.14 , pp. 2043-2052
    • Lemstrom, K.B.1    Aho, P.T.2    Bruggeman, C.A.3    Hayry, P.J.4
  • 46
    • 0028033784 scopus 로고
    • Investigation of cytomegalovirus infection as a risk factor for coronary atherosclerosis in the explanted hearts of patients undergoing heart transplantation
    • Dummer S, Lee A, Breinig MK, Kormos R, Ho M, Griffith B: Investigation of cytomegalovirus infection as a risk factor for coronary atherosclerosis in the explanted hearts of patients undergoing heart transplantation. J Med Virol 1994, 44:305-309.
    • (1994) J Med Virol , vol.44 , pp. 305-309
    • Dummer, S.1    Lee, A.2    Breinig, M.K.3    Kormos, R.4    Ho, M.5    Griffith, B.6
  • 47
    • 0029146442 scopus 로고
    • Infrequency of cytomegalovirus genome in coronary arteriopathy of human heart allografts
    • Gulizia JM, Kandolf R, Kendall TJ, Thieszan SL, Wilson JE, Radio SJ, Costanzo MR, Winters GL, Miller LL, McManus BM: Infrequency of cytomegalovirus genome in coronary arteriopathy of human heart allografts. Am J Pathol 1995, 147:461-475. This work convincingly demonstrates that cytomegalovirus genome is not frequent in CAV as compared with native atherosclerosis. Molecular techniques, including in situ hybridization and polymerase chain reaction, are used.
    • (1995) Am J Pathol , vol.147 , pp. 461-475
    • Gulizia, J.M.1    Kandolf, R.2    Kendall, T.J.3    Thieszan, S.L.4    Wilson, J.E.5    Radio, S.J.6    Costanzo, M.R.7    Winters, G.L.8    Miller, L.L.9    McManus, B.M.10
  • 48
    • 0028088381 scopus 로고
    • Effects of cyclosporine and 15-deoxyspergualin on coronary arteriosclerosis after heart transplantation in the rat
    • Nagamine S, Ohmi M, Tabayashi K, Iguchi A, Mohri H: Effects of cyclosporine and 15-deoxyspergualin on coronary arteriosclerosis after heart transplantation in the rat. J Heart Lung Transplant 1994, 13:895-898.
    • (1994) J Heart Lung Transplant , vol.13 , pp. 895-898
    • Nagamine, S.1    Ohmi, M.2    Tabayashi, K.3    Iguchi, A.4    Mohri, H.5
  • 49
    • 0028821565 scopus 로고
    • Experimental graft coronary artery disease in murine heterotopic cardiac transplant model
    • Hirozane T, Matsumon A, Furukawa Y, Sasayama S: Experimental graft coronary artery disease in murine heterotopic cardiac transplant model. Circulation 1995, 91:386-392.
    • (1995) Circulation , vol.91 , pp. 386-392
    • Hirozane, T.1    Matsumon, A.2    Furukawa, Y.3    Sasayama, S.4
  • 50
    • 0028304955 scopus 로고
    • Murine model of accelerated transplant arteriosclerosis
    • Shi C, Russell ME, Bianchi C, Newell JB, Haber E: Murine model of accelerated transplant arteriosclerosis. Circ Res 1995, 75:199-207. Establishes a novel mutine model of CAV that facilitate the molecular study of human CAV.
    • (1995) Circ Res , vol.75 , pp. 199-207
    • Shi, C.1    Russell, M.E.2    Bianchi, C.3    Newell, J.B.4    Haber, E.5
  • 52
    • 0028855572 scopus 로고
    • Comparison of rapamycin, RS 61443, cyclosporine, and low-dose heparin as treatment for transplant vasculopathy in a rat model of chronic allograft rejection
    • Schmid C, Heemann U, Azuma H, Tilney NL: Comparison of rapamycin, RS 61443, cyclosporine, and low-dose heparin as treatment for transplant vasculopathy in a rat model of chronic allograft rejection. Transplant Proc 1995, 27:438-439.
    • (1995) Transplant Proc , vol.27 , pp. 438-439
    • Schmid, C.1    Heemann, U.2    Azuma, H.3    Tilney, N.L.4
  • 54
    • 0028911829 scopus 로고
    • Immunosuppression in cardiac transplantation: A new era in immunopharmacology
    • Nair RV, Morris RE: Immunosuppression in cardiac transplantation: a new era in immunopharmacology. Curr Opin Cardiol 1995, 10:207-217.
    • (1995) Curr Opin Cardiol , vol.10 , pp. 207-217
    • Nair, R.V.1    Morris, R.E.2


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