Increased collagen synthesis by scleroderma skin fibroblasts in vitro. A possible defect in regulation or activation of scleroderma fibroblasts
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Endothelin release is inhibited by co-culture of endothelial cells with cells of vascular media
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Response of scleroderma fibroblasts to various growth factors
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Phenotypic differences in cytokine responsiveness of hypertrophie scar versus normal dermal fibroblasts
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Increased sensitivity of scleroderma fibrobiasts in culture to stimulation of protein and collagen synthesis by serum
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