Methotrexate in polymyalgia rheumatica: Preliminary results of an open, randomized study

Journal of Rheumatology

Volumn 23, Issue 4, 1996, Pages 624-628

  Ferraccioli, Gianfranco ^a   Salaffi, Fausto ^b   De Vita, Salvatore ^b   Casatta, Lucia ^b   Bartoli, Ettore ^b  

^a Section of Oncology and Molecular Pathology   (Italy)

^b NONE

Author keywords

Bone; Methotrexate; Polymyalgia; Steroids

Indexed keywords

METHOTREXATE; PREDNISONE;

ADULT; AGED; ARTICLE; BONE DENSITY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RHEUMATIC POLYMYALGIA;

AGED; ANTI-INFLAMMATORY AGENTS; ANTIRHEUMATIC AGENTS; BLOOD SEDIMENTATION; BONE DENSITY; C-REACTIVE PROTEIN; CREATININE; DRUG THERAPY, COMBINATION; FEMALE; FOLLOW-UP STUDIES; HUMANS; HYDROXYPROLINE; INJECTIONS, INTRAMUSCULAR; MALE; METHOTREXATE; OSTEOCALCIN; POLYMYALGIA RHEUMATICA; PREDNISONE; PROSPECTIVE STUDIES;

EID: 0029880859     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Bengtsson BA, Malmvall BE: The epidemiology of giant cell arteritis and polymyalgia rheumatica. Incidence of different clinical presentations and eye complications. Arthritis Rheum 1981;24:899-904.
2. Kyle V, Hazleman BL: Stopping steroids in polymyalgia rheumatica and giant cell artentis. BMJ 1990;300:344-5.
3. Chakravarty K, Elgabani SHS, Scott DGI, Merry P: A district audit on the management of polymyalgia rheumatica and giant cell arteritis. Br J Rheumatol 1994,33:152-6
4. Tugwell P, Bennett K, Gent M: Methotrexate in rheumatoid arthritis. Indications, contraindications, efficacy and safety. Ann Intern Med 1987;107:358-66
5. Hoffmann GS, Leavitt RY, Kerr GS, Fauci AS: The treatment of Wegener's granulomatosis with glucocorticoids and methotrexate. Arthritis Rheum 1992;35:1322-9.
6. Laan RFJM. van Riel PLCM, van de Putte LBA, van Erning LJTO, van't Hof MA, Lemmens JAM: Low dose prednisone induces rapid reversible axial bone loss in patients with rheumatoid arthritis Ann Intern Med 1993;119:963-8.
7. De Suva M, Hazleman BL: Azathioprine in giant cell arteritis/polymyalgia rheumatica: A double blind study. Ann Rheum Dis 1986:45:136-8.
8. Scheven BAA. van der Veen MJ, Damen CA, et al: Methotrexate effects on proliferation and differentiation of human osteoblasts in vitro (abstr) Arthritis Rheum 1994;(suppl)37:1204.
9. Wernick R, Smith DL: Central nervous system toxicity associated with weekly low-dose methotrexate treatment. Arthritis Rheum 1989;32-770-5.
10. van der Veen MJ, Dinant HJ, van Boorna-Frakfort C, van Albada-Kuipers GA, Bijlsma JWJ: Can methotrexate be used as a steroid sparing agent in the treatment of polymyalgia rheumatica and giant cell artentis? Ann Rheum Dis 1996; (in press).