A direct and convenient approach toward 2-alkenylcarbapenems via the Heck reaction

Tetrahedron Letters

Volumn 37, Issue 17, 1996, Pages 2987-2988

  Nishi, Koichi ^a   Narukawa, Yukitoshi ^a   Onoue, Hiroshi ^a  

^a SHIONOGI AND CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARBAPENEM DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0029880206     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)00480-7     Document Type: Article

References (12)

1. Ratcliffe, R. W.; Albers-Schönberg, G. In "Chemistry and Biology of β-Lactam Antibiotics" Morin, R. B.; Gorman, M., eds., Vol. 2, Academic Press, N. Y. 1982.
2. Nagahara, T.; Kametani, T. Heterocylces 1987, 25, 729.
3. (a) Rano, T. A.; Greenlee, M. L.; DiNinno, F. P. Tetrahedron Lett. 1990, 31, 2853.
4. (b) Yasuda, N.; Xavier, L.; Rieger, D. L.; Li, Y.; DeCamp, A. E.; Dolling, U.-H. Tetrahedron Lett. 1993, 34, 3211.
5. (c) Narukawa, Y.; Nishi, K.; Onoue, H. Tetrahedron Lett. in press.
6. Japan Patent Kokai 3-223, 285.
7. (a) Heck, R. F. Org. React. 1982, 27, 345.
8. (b) Cabri, W.; Candiani, I. Acc. Chem. Res. 1995, 28, 2.
9. 3c was purified by rapid, short column chromatography just before use.
10. 8Si: C, 65.03; H, 7.28; N, 4.21. Found: C, 64.90; H, 7.24; N, 4.30.
11. + 524.2442, Found 524.2442.
12. 13C-NMR spectroscopies.