Evidence of a glycemic threshold for the formation of pentosidine in diabetic dog lens but not in collagen

Diabetes

Volumn 45, Issue 5, 1996, Pages 587-594

  Nagaraj, Ramanakoppa H ^b   Kern, Timothy S ^b   Sell, David R ^b   Fogarty, John ^b   Engerman, Ronald L ^b   Monnier, Vincent M ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; CRYSTALLIN; FRUCTOSAMINE; GLUCOSE; GLYCOSYLATED HEMOGLOBIN; HYDROXYPROLINE; INSULIN; LENS PROTEIN; PENTOSIDINE; PEPSIN A; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CROSS LINKING; DIABETES MELLITUS; DOG; DURA MATER; EXTRACELLULAR MATRIX; FEMALE; FLUORESCENCE; GLUCOSE BLOOD LEVEL; GLYCATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LENS; MALE; MEMBRANE PERMEABILITY; NONHUMAN; PRIORITY JOURNAL;

EID: 0029879796     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diab.45.5.587     Document Type: Article

References (46)

1. Monnier VM, Kohn RR, Cerami A. Accelerated age-related browning of human collagen in diabetes mellitus. Proc Natl Acad Sci USA 81:583-587, 1984
2. Schnider SL, Kohn RR: Effects of age and diabetes mellitus on the solubility of collagen from human skin, tracheal cartilage and dura mater. Exp Gerontol 17:185-194, 1982
3. Lutze M, Bresnick GH: Lenses with diabetic patients "yellow" at an accelerated rate similar to older normals. Invest Ophthalmol Visual Sci 32:194-199, 1991
4. Engerman RL, Kern TS: Progression of incipient diabetic retinopathy during good glycemic control. Diabetes 36:808-812, 1987
5. Engerman RL, Kern TS: Hyperglycemia and development of glomerular pathology: diabetes compared with galactosemia. Kidney Int 36:41-45, 1988
6. Engerman RL, Kern TS, Larson ME: Nerve conduction velocity in dogs is reduced in diabetes and not by galactosemia. Metabolism 39:638-640, 1990
7. Reichard P, Nilson BY, Rosenavist U: The effect of long-term intensified insulin treatment on the development of microvascular complications of diabetes mellitus. N Engl J Med 329:304-309, 1993
8. The Diabetes Control and Complications Trial Research Group The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin dependent diabetes mellitus. N Engl J Med 329.977-986, 1993
9. Cerami A, Stevens VJ, Monnier VM: The role of nonenzymatic glycosylation in the sequelae of diabetes mellitus. Metabolism 38:431-438, 1979
10. Brownlee M, Vlassara H, Cerami A: Nonenzymatic glycosylation and the pathogenesis of diabetic complications. Ann Intern Med 101:527-537, 1984
11. Stevens VJ, Rouzer CA, Monnier VM, Cerami A: Diabetic cataract formation: potential role of glycosylation of lens crystalline. Proc Natl Acad Sci USA 75:2918-2922, 1978
12. Odetti P, Fogarty J, Sell DR, Monnier VM: Chromatographic quantitation of plasma and erythrocyte pentosidine in diabetic and uremic subjects. Diabetes 41:153-159, 1992
13. Nagaraj RH, Sell DR, Prabhakaram M, Ortwerth BJ, Monnier VM: High correlation between pentosidine protein crosslinks and pigmentation implicates ascorbate oxidation in human lens senescence and cataractogenesis. Proc Natl Acad Sci USA 88:10257-10261, 1991
14. Lyons TJ, Silverstri G, Dunn JA, Dyer DG, Baynes JW: Role of glycation in modification of lens crystallins in diabetic and non-diabetic senile cataracts. Diabetes 40:1010-1015, 1991
15. Dunn JA, Patrick JS, Thorpe SR, Baynes JW: Oxidation of glycated proteins: age-dependent accumulation of Nε-(carboxymethyl)lysine in lens proteins. Biochem J 28:9464-9468, 1990
16. Dunn JA, McCance DR, Thorpe SR, Lyons TJ, Baynes JW: Age-dependent accumulation of Nε-(carboxymethyl)lysine and Nε-(carboxymethyl)-hydroxylysine in human skin collagen. Biochem J 30:1205-1210, 1991
17. Miyata S, Monnier VM: Immunocytochemical detection of advanced glycosylation end products in diabetic tissues using monoclonal antibody to pyrraline. J Clin Invest 89.1102-1112, 1992
18. Sell DR, Monnier VM: End-stage renal disease and diabetes catalyze the formation of a pentose-derived crosslink from aging human collagen. J Clin Invest 85:380-384, 1990
19. Beisswenger PJ, Moore LL, Brinck-Johnsen T, Curphey TJ: Increased collagen-linked pentosidine levels and advanced glycosylation end products in early diabetic nephropathy. J Clin Invest 92:212-217, 1993
20. Smith PR, Somani HH, Thornalley PJ, Benn J, Sonksen PH: Evidence against the formation of 2-amino-6-(2-formyl-5-hydroxymethyl-pyrrol-1-yl)-hexanoic acid ("pyrraline") as early stage product or advanced glycation end product in non-enzymatic protein glycation. Clin Sci 84 87-93, 1993
21. Portero-Otin M, Nagaraj RH, Monnier VM: Chromatographic evidence for pyrraline formation during protein glycation in vitro and in vivo. Biochim Biophys Acta 1247:74-80, 1995
22. Nagaraj KH, Monnier VM: Isolation and characterization of a blue fluorophore from human eye lens crystallins: in vitro formation from Maillard reaction with ascorbate and ribose. Biochim Biophys Acta 1116:34-42, 1992
23. Makita Z, Vlassara H, Rayfield E, Cartwright K, Friedman E, Rodby R, Cerami A, Bucala R: Hemoglobin-AGE: a circulating marker for advanced glycosylation. Science 258:651-653, 1992
24. Araki N, Ueno B, Chakrabarti B, Morino Y, Horiuchi S: Immunological detection of advanced glycation end products in the human lens proteins and their positive correlation with aging. J Biol Chem 267:10211-10214, 1992
25. Sell DR, Lapolla A, Odetti P, Fogarty JF, Monnier VM: The relation between advanced glycosylation and the complications of long-standing insulin-dependent diabetes mellitus. Diabetes 41:1286-1292, 1992
26. McCance DR, Dyer DG, Dunn JA, Bailie KE, Thorpe SR, Baynes JW, Lyons TJ: Maillard products and their relation to complications in insulin-dependent diabetes mellitus. J Clin Invest 91:2470-2478, 1993
27. Beisswenger P, Moore LL, Brinck-Johnsen T, Curphey TJ. Increased collagen-linked levels and advanced glycosylation end products in early diabetic nephropathy. J Clin Invest 92:212-217, 1993
28. Brownlee M, Vlassara H, Kooney A, Ulrich P, Cerami A: Aminoguanidine prevents diabetes induced arterial wall protein crosslinking. Science 232:1629-1632, 1986
29. Hammes HP, Martin S, Federlin K, Geisen K, Brownlee M: Aminoguanidine treatment inhibits the development of diabetic retinopathy. Proc Natl Acad Sci USA 88:11555-11558, 1991
30. Corbett JH, Tilton RG, Chang K, Hasan KS, Ido Y, Wang JL, Sweetland MA, Lancaster JR, Williamson JR, McDaniel ML: Aminoguanidine, a novel inhibitor of nitric oxide formation, prevents diabetic vascular dysfunction. Diabetes 41:552-556, 1992
31. Kern TS, Engerman RL: Renal hemodynamics in experimentally galactosemic dogs and diabetic dogs. Metabolism 40.450-454, 1991
32. Stegeman H, Stalder S: Determination of hydroxyproline. Clin Chim Acta 236:458-467, 1967
33. Moore S, Stein WH: A modified ninhydrin method for the photometric determination of amino acid and related compound. J Biol Chem 211:907-913, 1954
34. Resmini P, Pelligrino L, Batelli G. Accurate quantification of furosine in milk and dairy products by a direct HPLC method. Ital J Food Sci 3:173-183, 1990
35. Baynes JW: Role of oxidative stress in development of complications in diabetes. Diabetes 40:405-412, 1991
36. Lou MF, Dickerson JE, Garadi R, York BM: Glutathione depletion in the lens of diabetic and galactosemic rats. Exp Eye Res 46:517-530, 1988
37. McPherson JD, Shilton BH, Walton DJ: Role of fructose in glycation and cross-linking of proteins. Biochemistry 27:1901-1907, 1988
38. Sasaki H, Giblin FJ, Winkler BS, Chakrapani B, Leverenz V, Chu-Chen S: A protective role for glutathione-dependent reduction of dehydroascorbic acid in lens epithelium. Invest Ophthalmol Visual Sci 36:1804-1817, 1995
39. Sato S, Takahashi Y, Wyman M, Kador P: Progression of sugar cataract in the dog. Invest Ophthalmol Visual Sci 32:1925-1931, 1991
40. Fuller JH, Shipley MJ, Rose G, Jarrett RJ, Keen H: Coronary heart disease risk and impaired glucose tolerance: the Whitehall Study. Lancet 1:1373-1376, 1980
41. Pirart J. Diabetes mellitus and its degenerative complications, a prospective study of 4,400 patients observed between 1947 and 1973. Diabetes Care 1:168-263, 1978
42. Dorf A, Ballintine EJ, Bennett PH, Miller M. Retinopathy in Pima Indians: relationships to glucose level, duration of diabetes, age at diagnosis of diabetes, and age at examination in a population with a high prevalence of diabetes mellitus. Diabetes 25 554-560, 1976
43. Jarrett RJ, Keen H. Hyperglycemia and diabetes Lancet 1 1009-1012, 1976
44. Krolewski AS, Laffel LMB, Krolewski M, Quinn MA, Warram JH: Glycosylated hemoglobin and the risk of microalbuminuria in patients with insulin-dependent diabetes mellitus. N Engl J Med 332:1251-1255, 1995
45. Warram JH, Manson JE, Krolewski AS. Glycosylated hemoglobin and the risk of retinopathy in insulin-dependent diabetes mellitus. N Engl J Med 332:1305-1306, 1995
46. Danne T, Weber B, Hartman R, Endres I, Burger W, Hovener G: Long-term glycemic control has a nonlinear association to the frequency of background retinopathy in adolescent with diabetes. Diabetes Care 17:1300-1396, 1994