Complement-induced release of monocyte chemotactic protein-1 from human smooth muscle cells: A possible initiating event in atherosclerotic lesion formation

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 16, Issue 5, 1996, Pages 673-677

  Torzewski, Jan ^b   Oldroyd, Rodney ^a   Lachmann, Peter ^a   Fitzsimmons, Colin ^c   Proudfoot, Diane ^c   Bowyer, David ^c  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF ULM   (Germany)

^c NONE

Author keywords

atherogenesis; complement; monocyte chemotactic protein 1; monocytes; smooth muscle cells

Indexed keywords

COMPLEMENT COMPONENT C5B; COMPLEMENT COMPONENT C6; COMPLEMENT COMPONENT C7; COMPLEMENT COMPONENT C8; COMPLEMENT COMPONENT C9; COMPLEMENT MEMBRANE ATTACK COMPLEX; MONOCYTE CHEMOTACTIC PROTEIN 1;

ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CHEMOTAXIS; CONTROLLED STUDY; HUMAN; HUMAN CELL; MONOCYTE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN SECRETION; VASCULAR SMOOTH MUSCLE;

EID: 0029879772     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.16.5.673     Document Type: Article

References (25)

1. Ross R. Atherosclerosis: a defense mechanism gone awry. Am J Pathol. 1993;143:987-1002.
2. Faruqi MR, Di Corleto PE. Mechanisms of monocyte recruitment and accumulation. Br Heart J. 1993;69:19-29.
3. Leonard EJ, Yoshimura T. Human monocyte chemotactic protein-1 (MCP-1). Immunol Today. 1990;3:97-101.
4. Yla Hertualla SY, Lipton BA, Rosenfeld ME, Sarkioja T, Yoshimura T, Leonard EJ, Witztum JL, Steinberg D. Expression of monocyte chemotactic protein 1 in monocyte-rich areas of human and rabbit atherosclerotic lesions. Proc Natl Acad Sci USA. 1993; 88:5252-5256.
5. Wang JM, Sica A, Peri G, Walter S, Padura IM, Libby P, Ceska M, Lindley I, Colotta F, Monotovani A. Expression of monocyte chemotactic protein-1 and interleukin-8 by cytokine-activated human vascular smooth muscle cells. Arterioscler Thromb. 1991;11:1166-1174.
6. Bhakdi S, Hugo F, Tranum-Jensen J. Functions and relevance of terminal complement sequence. Blood. 1990;60:309-318.
7. Benzaquen LR, Nicholson-Weller A, Halperin JA. Terminal complement protein C5b-9 releases bFGF and PDGF from endothelial cells. J Exp Med. 1994;179:985-992.
8. Lovett DH, Haensch GM, Goppelt M, Resch K, Gemsa F. Activation of glomerular mesangial cells by the terminal membrane attack complex of complement. J Immunol. 1987;138:2473-2480.
9. Hansch GM, Torbohm I, Rother K. Chronic glomerulonephritis: inflammatory mediators stimulate the collagen synthesis in glomerular epithelial cells. Int Arch Allergy Appl Immunol. 1989;88: 139-143.
10. Niculescu F, Hugo F, Rus HG, Vlaicu R, Bhakdi S. Quantitative evaluation of the terminal C5b-9-complex by ELISA in human atherosclerotic lesions. Clin Exp Immunol. 1987;69:477-483.
11. Seifert PS, Hugo F, Tranum-Jensen J, Zahringer U, Muhly M, Bhakdi S. Isolation and characterization of a complement-activating lipid extracted from human atherosclerotic lesions. J Exp Med. 1990;172:547-557.
12. Bhakdi S, Dorweiler B, Kirchmann R, Torzewski J, Weise E, Tranum-Jensen J, Walev I, Wieland E. On the pathogenesis of atherosclerosis: enzymatic modification of low-density lipoprotein to an atherogenic moiety. J Exp Med. 1995;182:1959-1971.
13. Morgan BP. Effects of the membrane attack complex on nucleated cells. Curr Top Microbiol Immunol. 1992;178:115-140.
14. Seifert PS, Roth I, Schmidt W, Oelert H, Okada N, Okada H, Bhakdi S. CD59 (homologous restriction factor 20), a plasma membrane protein that protects against complement C5b-9 attack in human atherosclerotic lesions. Atherosclerosis. 1992;96:135-145.
15. Thompson MB, Lachmann PJ. Reactive lysis: the complement-mediated lysis of unsensitized cells I. J Exp Med. 1970;131:629-642.
16. Lachmann PJ, Thompson MB. Reactive lysis: the complement-mediated lysis of unsensitized cells II. J Exp Med. 1970;131:643-655.
17. Denholm EM, Wolber FM. A simple method for the purification of human peripheral blood monocytes. J Immunol Methods. 1991;144: 247-250.
18. Ross R. The smooth muscle cell, II: growth of smooth muscle cells in culture and formation of elastic fibers. J Cell Biol. 1971;50: 172-177.
19. Martinet Y, Martinet N, Vignaud JM, Plenat F. Blood monocyte chemotaxis. J Immunol Methods. 1994;174:209-214.
20. Yoshimura T, Leonard EJ. Identification of high afiinity-receptors for human monocyte chemoattractant protein-1 on human monocytes. J Immunol. 1989;145:292-297.
21. Seifert PS, Hugo F, Hansson GK, Bhakdi S. Prelesional complement activation in experimental induced atherogenesis. Lab Invest. 1989;60:747-754.
22. Geertinger P, Sørensen H. On the reduced atherogenic effect of cholesterol feeding on rabbits with congenital (Cb) deficiency. Artery. 1974;1:177-184.
23. Cybulski A, Cyr M. Phosphatidyl-choline-directed phospholipase C: activation by complement C5b-9. Am J Physiol. 1993;265: 551-556.
24. Cochrane CG, Mueller-Eberhard HJ. The derivative of two distinct anaphylatoxin activities from the third and fifth component of human complement. J Exp Med. 1968;127:371-380.
25. Penn MS, Saidel GM, Chisolm GM. Relative significance of endothelium and internal elastic lamina in regulating the entry of macromolecules into arteries in vivo. Circ Res. 1994;74:74-82.