Sequence-specific actinomycin D binding to single-stranded DNA inhibits HIV reverse transcriptase and other polymerases

Biochemistry

Volumn 35, Issue 11, 1996, Pages 3525-3533

  Rill, Randolph L ^a   Hecker, Karl H ^a  

^a FLORIDA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DACTINOMYCIN; EXONUCLEASE; RNA DIRECTED DNA POLYMERASE; SINGLE STRANDED DNA;

ARTICLE; COVALENT BOND; DNA BINDING; DNA RNA HYBRIDIZATION; DNA TEMPLATE; DRUG RECEPTOR BINDING; ENZYME ACTIVE SITE; ENZYME SUBSTRATE COMPLEX; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; RECEPTOR AFFINITY;

BASE COMPOSITION; BASE SEQUENCE; DACTINOMYCIN; DNA; DNA ADDUCTS; DNA, SINGLE-STRANDED; DNA-DIRECTED DNA POLYMERASE; ENZYME INHIBITORS; HIV-1 REVERSE TRANSCRIPTASE; MOLECULAR SEQUENCE DATA; REVERSE TRANSCRIPTASE INHIBITORS; RNA-DIRECTED DNA POLYMERASE; TEMPLATES, GENETIC; TRANSCRIPTION, GENETIC;

EID: 0029879748     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9530797     Document Type: Article

References (40)

1. Aivasashvilli, V. A., & Beabealashvilli, R. Sh. (1983) FEBS Lett. 160, 124.
2. Brockmann, H. (1974) Cancer Chemother, Rep. 58, 9.
3. Bunte, T., Novak, U., Friedrich, R., & Moelling, K. (1980) Biochim. Biophys. Acta 610, 241.
4. Cantor, C. R., Warshaw, M. M., & Shapiro, H. (1970) Biopolymers 9, 1059.
5. Chen, F. M. (1988) Biochemistry 27, 1843.
6. Crenshaw, J., Bailey. S., & Graves, D. E. (1993) in Molecular Aspects of Ligand - DNA Interactions, A Symposium sponsored by The Center in Molecular Toxicology, Vanderbilt University Medical Center, Nashville, TN (unpublished).
7. Goldberg, I. H., & Friedman, P. A. (1971) Annu. Rev. Biochem. 40, 775.
8. Goldberg, I. H., Rabinowitz, M., & Reich, E. (1962) Proc. Natl. Acad. Sci. USA. 48, 2094.
9. Goodisman, J., Rehfuss, R., Ward, B., & Dabrowiak, J. C. (1992) Biochemistry 31, 1046.
10. Graves, D. E., & Wadkins, R. M. (1989) J. Biol. Chem. 264, 7262
11. Haseltine, W. A., & Wong-Staal, F. (1991) in Genetic Structure and Regulation of HIV. p 560, Raven. New York.
12. Kamitori, S., & Takusaeawa, F. (1992) J. Mol. Biol. 225, 445.
13. Kerr, C., & Sadowski, P. D. (1972) J. Biol. Chem. 247, 311.
14. Krugh, T. R., & Chen, Y. C. (1975) Biochemistry 14, 4912.
15. Liu, X., Chen, H., & Patel, D. J. (1991) J. Bioniol. NMR 1, 323.
16. Lybrand, T. P., Brown, S. C., Creighton, S., Shafer. R. H., & Kollman, P. A. (1986) J Mol. Biol. 191, 495.
17. Manly, K. F., Smoler, D. F., Bromfield, E., & Baltimore, D. (1971) J. Virol. 7, 106.
18. McDonnell, J. P., Garapin, A.-C., Levinson, W. E., Quintrell, N., Fanshier, L., & Bishop, J. M. (1970) Nature 228, 433.
19. Mitsuya, H., Yarchoan, R., & Broder, S. (1990) Science 249, 1533.
20. Müller, W., & Crothers, D. M. (1968) J. Mol. Biol. 35, 251.
21. Novak, U., Friedrich, R., & Moelling, K. (1979) J. Virol. 30, 438.
22. Phillips, D. R., & Crothers, D. M. (1986) Biochemistry 25, 7355.
23. Pisa-Williamson, D., & Fuller, C. W. (1992) in Comments, Vol. 19 (No. 2), p 32. U.S. Biochemical Corp., Cleveland, OH.
24. Reich, E., & Goldberg. I. H. (1964) Prog. Nucleic Acid Res. Mol. Biol. 3, 183.
25. Rill, R. L., Marsch, G. A., & Graves, D. E. (1989) J. Biomol. Struct. Dyn. 7, 591.
26. Sanger, F., Niklen, S., & Coulson, A. R. (1977) Proc. Nail. Acad. Sci. U.S.A. 74, 5463.
27. Sobell, H. M. (1985) Proc. Natl. Acad. Sci. U.S.A. 82, 5328.
28. Sobell, H. M., & Jain, S. C. (1972) J. Mol. Biol. 68, 21.
29. Sobell, H. M., Jain, S. C., Sakore, T. D., & Nordman, C. E. (1971) Nature (London), New Biol. 231, 200.
30. Tabor, S., & Richardson, C. C. (1987) Proc. Natl. Acad. Sci. U.S.A. 84, 4767.
31. Tabor, S., & Richardson, C. C. (1990) J. Biol. Chem. 265, 8322.
32. Tullius, T. D. (1989) Annu. Rev. Biophys. Biophys. Chem. 18, 213.
33. Wadkins, R. M., & Jovin, T. M. (1991) Biochemistry 30, 9469.
34. Waksman, S. A., & Woodruff, H. B. (1940) Proc. Soc. Exp. Biol. Med. 45, 609.
35. White, R. J., & Phillips, D. R. (1988) Biochemistry 27, 9122.
36. White, R. J., & Phillips, D. R. (1989) Biochemistry 28, 6259.
37. Wilson, W. D., Jones, R. L., Zon, G., Scott, E. V., Banville, D. L., & Marzilli, L. G. (1986) J. Am. Chem. Soc. 108, 7113.
38. Wong-Staal, F., & Haseltine, W. A. (1992) MoL Genet, Med. 2, 189.
39. Yanagi, K., Prive, G. G., & Dickerson, R. E. (1991) J. Mol. Biol. 217, 201.
40. Zapp, M. L., Stern, S., & Green, M. R. (1993) Cell 74, 969.