Ret and trk proto-oncogene activation in thyroid papillary carcinomas in french patients from the champagne-ardenne region

Clinical Biochemistry

Volumn 29, Issue 3, 1996, Pages 267-271

  Delvincourt, Chantal ^a   Patey, Martine ^b   Flament, Jean Bernard ^b   Suarez, Horacio G ^c   Larbre, Helene ^a   Jardillier, Jean Claude ^a   Delisle, Marie Joelle ^a  

^a INSTITUT JEAN GODINOT   (France)

^b REIMS UNIVERSITY HOSPITAL   (France)

^c Inst Rech Scientifiques le Cancer   (France)

Author keywords

proto oncogene activation; ret; thyroid carcinoma; trk

Indexed keywords

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; DNA PROBE; FEMALE; GENE ACTIVATION; GENE REARRANGEMENT; HUMAN; MALE; PRIORITY JOURNAL; PROTO ONCOGENE; SOUTHERN BLOTTING; THYROID PAPILLARY CARCINOMA;

EID: 0029879618     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/0009-9120(96)00006-9     Document Type: Article

References (28)

1. Wynford-Thornas D. Molecular basis of epithelial tumorigenesis: The thyroid model. Crit Rev Oncog 1993; 4: 1-23.
2. Fusco A, Grieco M, Santoro M, et al. A new oncogene in human thyroid papillary carcinomas and their lymph-nodal metastases. Nature 1987; 328: 170-172.
3. Grieco M, Santoro M, Berlingieri MT et al. PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas. Cell 1990; 60: 557-563.
4. Pierotti MA, Santoro M, Jenkins RB et al. Characterization of an inversion on the long arm of chromosome 10 juxtaposing D10S170 and RET and creating the oncogenic sequence RET/PTC. Proc Natl Acad Sci USA 1992; 89: 1616-1620.
5. Grieco M, Cerrato A, Santoro M, Fusco A, Melillo RM, Vecchio G. Cloning and characterization of H4(D10S170), a gene involved in RET rearrangements in vivo. Oncogene 1994; 9: 2531-2535.
6. Bongarzone I, Monzini N, Borrello MG et al. Molecular characterization of a thyroid tumor-specific transforming sequence formed by the fusion of ret tyrosine kinase and the regulatory subunit RIα of cyclic AMP-dependent protein kinase A. Mol Cell Biol 1993; 13: 358-366.
7. Santoro M, Dathan NA, Berlingieri MT et al. Molecular characterization of RET/PTC3; a novel rearranged version of the RET proto-oncogene in a human thyroid papillary carcinoma. Oncogene 1994; 9: 509-516.
8. Bongarzone I, Butti MG, Coronelli S et al. Frequent activation of ret protooncogene by fusion with a new activating gene in papillary thyroid carcinomas. Cancer Res 1994; 54: 2979-2985.
9. Martin-Zanca D, Hughes SH, Barbacid M. A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences. Nature 1986; 319: 743-748.
10. Radice P, Sozzi G, Miozzo M et al. The human tropomyosin gene involved in the generation of the TRK oncogene maps to chromosome 1q31. Oncogene 1991; 6: 2145-2148.
11. Greco A, Pierotti MA, Bongarzone I, Pagliardini S, Lanzi C, Della Porta G: Trk-T1 is a novel oncogene formed by the fusion of TPR and TRK genes in human papillary thyroid carcinomas. Oncogene 1992; 7: 237-242.
12. Borrello MG, Pelicci G, Arighi E et al. The oncogenic versions of the Ret and Trk tyrosine kinases bind Shc and Grb2 adaptor proteins. Oncogene 1994; 9: 1661-1668.
13. Takahashi M: Ret proto-oncogene and human diseases (Review). Int J Oncol 1994; 4: 81-84.
14. Bongarzone I, Pierotti MA, Monzini N et al. High frequency of activation of tyrosine kinase oncogenes in human papillary thyroid carcinomas. Oncogene 1989; 4: 1457-1462.
15. Santoro M, Carlomagno F, Hay ID et al. Ret oncogene activation in human thyroid neoplasms is restricted to the papillary cancer subtype. J Clin Invest 1992; 89: 1517-1522.
16. Said S, Schlumberger M, Suarez HG: Oncogenes and anti-oncogenes in human epithelial thyroid tumors. J Endocrinol Invest 1994; 17: 371-379.
17. Wajjwalku W, Nakamura S, Hasegawa Y et al. Low frequency of rearrangements of the ret and trk protooncogenes in japanese thyroid papillary carcinomas. Jpn J Cancer Res 1992; 83: 671-675.
18. Namba H, Yamashita S, Pei HC et al. Lack of PTC gene (ret proto-oncogene rearrangement) in human thyroid tumors. Endocrinol Japon 1991; 38: 627-632.
19. TPC) in papillary thyroid carcinomas from Saudi Arabia. Cancer 1994; 73: 176-180.
20. TPC/PTC transcripts in thyroid adenomas and adenomatous goiter by an RT-PCR method. Oncogene 1991; 6: 1667-1672.
21. Maniatis T, Fritsch E, Sambrook J. Molecular Cloning: a Laboratory Manual. New York, Cold Spring Harbor, 1990.
22. Ishizaka Y, Tahira T, Ochiai M, Ikeda I, Sugimura T, Nagao M. Molecular cloning and characterization of ret-II oncogene. Oncogene Res 1988; 3: 193-197.
23. Santoro M, Sabino N, Ishizaka Y, et al. Involvement of RET oncogene in human tumours: specificity of RET activation to thyroid tumours. Br J Cancer 1993; 68: 460-464.
24. TPC oncogene in human thyroid cancers. Oncogene 1992; 7: 1331-1337.
25. Fabien N, Paulin C, Santoro M et al. Detection of RET oncogene activation in human papillary thyroid carcinomas by in situ hybridisation. Br J Cancer 1992; 66: 1094-1098.
26. Wright P, Williams ED, Lemoine NR, Wynford-Thomas D. Radiation-associated and «spontaneous» human thyroid carcinomas show a different pattern of ras oncogene mutation. Oncogene 1991; 6: 471-473.
27. Suarez HG, Du Villard JA, Severino M et al. Presence of mutations in all three ras genes in human thyroid tumors. Oncogene 1990; 5: 565-570.
28. Manenti G, Pilotti S, Re FC, Della Porta G, Pierotti MA. Selective activation of ras oncogenes in follicular and undifferentiated thyroid carcinomas. Eur J Cancer 1994; 30A: 987-993.