The dendritic cell: Its potent role in the respiratory immune response

Cell Biology International

Volumn 20, Issue 2, 1996, Pages 111-120

  Lambrecht, B N ^a   Pauwels, R A ^a   Bullock, G R ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

Antigen presentation; Asthma pathogenesis; Dendritic cell; Localization; Lung; Origin

Indexed keywords

ANTIGEN; CYTOKINE;

ANTIGEN PRESENTATION; ARTICLE; CELL CULTURE; CELL FUNCTION; CELL LINEAGE; CELL MATURATION; CELL MIGRATION; CELL STRUCTURE; DENDRITIC CELL; IMMUNE RESPONSE; PHENOTYPE; RESPIRATORY SYSTEM; RESPIRATORY TRACT DISEASE; T LYMPHOCYTE;

EID: 0029879454     PISSN: 10656995     EISSN: None     Source Type: Journal    
DOI: 10.1006/cbir.1996.0015     Document Type: Article

References (69)

1. BENHAM A, TULP A, NEEFJES J, 1995. Synthesis and assembly of MHC-peptide complexes. Immunol Today 16: 359-362.
2. BILYK N, HOLT PG, 1993. Inhibition of the immunosuppressive activity of resident pulmonary alveolar macrophages by granulocyte/macrophage colony-stimulating factor. J Exp Med 177: 1773-1777.
3. BOWERS WE, BERKOWITZ MR, LA BADIE JH, KLINKERT WEF, 1983. Differentiation of dendritic cells from rat bone marrow. Transplant Proc 15: 1611-1612.
4. CAUX C, DEZUTTERDAMBUYANT C, SCHMITT D, BANCHEREAU J, 1992. GM-CSF and TNF-alfa cooperate in the generation of dendritic Langerhans cells. Nature 360: 258-261.
5. CAUX C, VANBERVLIET B, MASSACRIER C, AZUMA M, OKUMURA K, LANIER LL, BANCHEREAU J, 1994. B70/B7-2 Is identical to CD86 and is the major functional ligand for CD28 expressed on human dendritic cells. J Exp Med 180: 1841-1847.
6. CROFT M, 1994. Activation of naive, memory and effector T cells. Curr Opin Immunol 6: 431-437.
7. CROWLEY MT, INABA K, STEINMAN RM, 1990. Dendritic cells are the principal cells in mouse spleen bearing immunogenic fragments of foreign proteins. J Exp Med 172: 383-386.
8. EGNER W, MCKENZIE JL, SMITH SM, BEARD MEJ, HART DNJ, 1993. Identification of potent mixed leukocyte reaction-stimulatory cells in human bone marrow. J Immunol 150: 3043-3053.
9. GIESELER RKH, ROBER RA, KUHN R, WEBER K, OSBORN M, PETERS JH, 1991. Dendritic accessory cells derived from rat bone marrow precursors under chemically defined conditions in vitro belong to the myeloid lineage. Eur J Cell Biol 54: 171-181.
10. GONG JL, MCCARTHY KM, ROGERS RA, SCHNEEBERGER E, 1994. Interstitial lung macrophages interact with dendritic cells to present antigenic peptides derived from particulate antigens to T cells. Immunology 81: 343-351.
11. GRABBE S, BEISSERT S, SCHWARZ T, GRANSTEIN RD, 1995. Dendritic cells as initiators of tumor immune responses: A possible strategy for tumor immunotherapy? Immunol Today 16: 117-121.
12. HANCE AJ, 1993. Pulmonary immune cells in health and disease: dendritic cells and Langerhans' cells. Eur Respir J 6: 1213-1220.
13. HAVENITH CEG, BREEDIJK AJ, HOEFSMIT ECM, 1992. Effect of bacillus Clamette-Guérin inoculation on numbers of dendritic cells in bronchoalveolar lavages of rats. Immunobiology 184: 336-347.
14. HAVENITH CEG, BREEDIJK AJ, BETJES MGH, CALAME W, BEELEN RHJ, HOEFSMIT ECM, 1993a. T cell priming in situ by intratracheally instilled antigen-pulsed dendritic cells. Am J Respir Cell Mol Biol 8: 319-324.
15. HAVENITH CEG, VAN MIERT PPMC, BREEDIJK AJ, BEELEN RHJ, HOEFSMIT ECM, 1993b. Migration of dendritic cells into the draining lymph nodes of the lung after intratracheal instillation. Am J Respir Cell Mol Biol 9: 484-488.
16. HEUFLER C, KOCH F, SCHULER G, 1988. Granulocyte/ macrophage colony stimulating factor and interleukin 1 mediate the maturation of murine epidermal Langerhans cells into potent immunostimulatory dendritic cells. J Exp Med 167: 700-705.
17. HOLGATE ST, 1993. Asthma: past, present and future. Eur Respir J 6: 1507-1520.
18. HOLT PG, DEGEBRODT A, O'LEARY C, KRSKA K, PLOZZA T, 1985. T-cell activation by antigen-presenting cells from lung tissue digests: suppression by endogenous macrophages. Clin Exp Immunology 62: 586-593.
19. HOLT PG, 1993. Regulation of antigen-presenting cell function(s) in lung and airway tissues. Eur Respir J 6: 120-129.
20. HOLT PG, HAINING S, NELSON DJ, SEDGWICK JD, 1994. Origin and steady-state turnover of class II MHC-bearing dendritic cells in the epithelium of the conducting airways. J Immunol 153: 256-261.
21. HOSOI J, MURPHY GF, EGAN CL, LERNER EA, GRABBE S, ASAHINA A, GRANSTEIN RD, 1993. Regulation of Langerhans cell function by nerves containing calcitonin gene-related peptide. Nature 363: 159-163.
22. IBRAHIM MAA, CHAIN BM, KATZ DR, 1995. The injured cell: role of the dendritic cell system as a sentinel receptor pathway. Immunol Today 16: 181-186.
23. INABA K, METLAY JP, CROWLEY MT, STEINMAN RM, 1990. Dendritic cells pulsed with protein antigens in vitro can prime antigen specific, MHC-restricted T cells in situ. J Exp Med 172: 631-640.
24. INABA K, INABA M, ROMANI N, AYA H, DEGUCHI M, IKEHARA S, MURAMATSU S, STEINMAN RM, 1992a. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J Exp Med 176: 1693-1702.
25. INABA K, STEINMAN RM, WITMERPACK M, AYA H, INABA M, SUDO T, WOLPE S, SCHULER G, 1992b. Identification of proliferation dendritic cell precursors in mouse blood. J Exp Med 175: 1157-1167.
26. INABA K, INABA M, NAITO M, STEINMAN RM, 1993. Dendritic cell progenitors phagocytose particulates, including bacillus Calmette-Guerin organisms, and sensitize mice to mycobacterial antigens in vivo. J Exp Med 178: 479-488.
27. INABA K, WITMERPACK M, INABA M, et al., 1994. The tissue distribution of the B7-2 costimulator in mice: Abundant expression on dendritic cells in situ and during maturation in vitro. J Exp Med 180: 1849-1860.
28. JANEWAY CA JR, BOTTOMLY K, 1994. Signals and signs for lymphocyte responses. Cell 76: 275-285.
29. JIANG W, SWIGGARD WJ, HEUFLER C, PENG M, MIRZA A, STEINMAN RM, NUSSENZWEIG MC, 1995. The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing. Nature 375: 151-155.
30. KILSHAW PJ, 1993. Expression of the mucosal T cell integrin alfaM290beta7 by a major subpopulation of dendritic cells in mice. Eur J Immunol 23: 3365-3368.
31. KIPS JC, TAVERNIER J, PAUWELS RA, 1992. Tumor necrosis factor causes bronchial hyperresponsiveness in rats. Am Rev Respir Dis 145: 332-336.
32. KRADIN RL, MCCARTHY KM, XIA W, LAZARUS D, SCHNEEBERGER E, 1991. Accessory cells of the lung: Interferon-gamma increases Ia+ Dendritic cells in the lung without augmenting their accessory activities. Am J Respir Cell Mol Biol 4: 210-218.
33. KRADIN RL, XIA W, PINTO C, ZHAO L-H, 1994. Substance P-containing unmyelinated C-fibers are present in immediate proximity to airway DC and may promote their migration during inflammation. Am J Respir Crit Care Med 149: A267 (Abstract).
34. KUPIEC-WEGLINSKY JW, AUSTYN JM, MORRIS PJ, 1988. Migration patterns of dendritic cells in the mouse. Traffic from the blood, and T cell-dependent and -independent entry to lymphoid tissues. J Exp Med 167: 632-645.
35. LARSEN CP, RITCHIE SC, HENDRIX R, LINSLEY PS, HATHCOCK KS, HODES RJ, LOWRY RP, PEARSON TC, 1994. Regulation of immunostimulatory function and costimulatory molecule (B7-1 and B7-2) expression on murine dendritic cells. J Immunol 152: 5208-5219.
36. LORENZ RG, BLUM JS, ALLEN PM, 1990. Constitutive competition by self proteins for antigen presentation can be overcome by receptor-enhanced uptake. J Immunol 144: 1600-1606.
37. LU L, RUDERT WA, QIAN SG, et al., 1995. Growth of donor-derived dendritic cells from the bone marrow of murine liver allograft recipients in response to granulocyte/ macrophage colony-stimulating factor. J Exp Med 182: 379-387.
38. LUDEWIG B, GRAF D, GELDERBLOM HR, BECKER Y, KROCZEK RA, PAULI G, 1995. Spontaneous apoptosis of dendritic cells is efficiently inhibited by TRAP (CD40-ligand) and TNF-alpha, but strongly enhanced by interleukin-10. Eur J Immunol 25: 1943-1950.
39. MACATONIA SE, KNIGHT SE, EDWARDS AJ, GRIFFITHS S, FRYER PJ, 1987. Localization of antigen on lymph node dendritic cells after exposure to the contact sensitizer fluorescein isothiocyanate. J Exp Med 166: 1654.
40. MACATONIA SE, HOSKEN NA, LITTON M, et al., 1995. Dendritic cells produced IL-12 and direct the development of Th1 cells from naive CD4(+) T cells. J Immunol 154: 5071-5079.
41. MCWILLIAM AS, NELSON DJ, THOMAS JA, HOLT PG, 1994. Rapid dendritic cell recruitment is a hallmark of the acute inflammatory response at mucosal surfaces. J Exp Med 179: 1331-1336.
42. MOLLER GM, OVERBEEK SE, VAN HELDEN CG, MULDER PG, POSTMA DS, HOOGSTEDEN HC, 1995. Increased numbers of DCs in the bronchial mucosa of atopic asthmatic patients: downregulation by inhaled corticosteroids. Am J Respir Crit Care Med 151: A776 (Abstract).
43. MUDDE GC, BHEEKHA R, BRUIJNZEEL-KOOMEN CA, 1995. IgE-mediated antigen presentation. Allergy 50: 193-199.
44. NELSON DJ, MCMENAMIN C, MCWILLIAM AS, BRENAN M, HOLT PG, 1994. Development of the airway intraepithelial dendritic cell network in the rat from class II major histocompatibility (Ia)-negative precursors: Differential regulation of Ia expression at different levels of the respiratory tract. J Exp Med 179: 203-212.
45. NELSON DJ, MCWILLIAM AS, HAINING S, HOLT PG, 1995. Modulation of airway intraepithelial dendritic cells following exposure to steroids. Am J Respir Crit Care Med 151: 475-481.
46. NIJMAN HW, KLEIJMEER MJ, OSSEVOORT MA, et al., 1995. Antigen capture and major histocompatibility class II compartments of freshly isolated and cultured human blood dendritic cells. J Exp Med 182: 163-174.
47. PETERS JH, RUPPERT J, GIESELER RKH, NAJAR HM, XU H, 1991. Differentiation of human monocytes into CD14 negative accessory cells: do DCs derive from the monocytic lineage? Pathobiology 59: 122-126.
48. REID CD, FRYER PJ, CLIFFORD C, KIRK A, TIKERPAE J, KNIGHT SC, 1990. Identification of hematopoietic progenitors of macrophages and dendritic Langerhans Cells (DL-CFU) in human bone marrow and peripheral blood. Blood 76: 1139-1149.
49. REIS E SOUSA C, STAHL PD, AUSTYN JM, 1993. Phagocytosis of antigens by Langerhams Cells in vitro. J Exp Med 178: 509-519.
50. ROAKE JA, RAO AS, MORRIS PJ, LARSEN CP, HANKINS DF, AUSTYN JM, 1995. Dendritic cell loss from nonlymphoid tissues after systemic administration of lipopolysaccharide, tumor necrosis factor, and interleukin 1. J Exp Med 181: 2237-2247.
51. SALLUSTO F, CELLA M, DANIELI C, LANZAVECCHIA A, 1995. Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: down-regulation by cytokines and bacterial products. J Exp Med 182: 389-400.
52. SANTIAGOSCHWARZ F, DIVARIS N, KAY C, CARSONS SE, 1993. Mechanisms of tumor necrosis factor-granulocyte-macrophage-colony stimulating factor-induced dendritic cell development. Blood 82: 3019-3028.
53. SCHON-HEGRAD MA, OLIVER J, MCMENAMIN PG, HOLT PG, 1991. Studies on the density, distribution and surface phenotype of intraepithelial class II major histocompatibility complex antigen (Ia)-bearing dendritic cells (DC) in the conducting airways. J Exp Med 173: 1345-1356.
54. SERTL K, TAKEMURA T, TSCHACHLER E, FERRANS VJ, KALINER MA, SHEVACH EM, 1986. Dendritic cells with antigen-presenting capability reside in airway epithelium, lung parenchyma, and visceral pleura. J Exp Med 163: 436-451.
55. SHAH PD, GILBERTSON SM, ROWLEY DA, 1985. Dendritic cells that have interacted with antigen are targets for natural killer cells. J Exp Med 162: 625-636.
56. SORNASSE T, FLAMAND V, DE BECKER G, et al., 1992. Antigen pulsed dendritic cells can efficiently induce an antibody response in vivo. J Exp Med 175: 15.
57. STAHL P, SCHLESINGER PH, SIGARDSON E, RODMAN JS, LEE YC, 1980. Receptor mediated pinocytosis of mannose glycoconjugates by macrophages: characterization and evidence for receptor recycling. Cell 19: 207-215.
58. STAHL PD, 1992. The mannose receptor and other macrophage lectins. Curr Opin Immunol 4: 49-52.
59. STEINMAN RM, LUSTIG DS, COHN ZA, 1974. Identification of a novel cell type in peripheral lymphoid organs of mice. III. Functional properties in vivo. J Exp Med 139: 1431-1445.
60. STEINMAN RM, 1991. The dendritic cell system and its role in immunogenicity. Ann Rev Immunol 9: 271-296.
61. STEINMAN RM, COHN ZA, 1974. Identification of a novel cell type in peripheral lymphoid organs of mice. II. Functional properties in vitro. J Exp Med 139: 380-397.
62. STEINMAN RM, SWANSON J, 1995. The endocytic activity of dendritic cells. J Exp Med 182: 283-288.
63. STINGL G, WOLFF-SCHREINER EC, PICHLER WJ, KNAPP W, WOLFF K, 1977. Epidermal Langerhans cells bear Fc and C3 receptors. Nature 268: 245.
64. TAZI A, BOUCHONNET F, GRANDSAIGNE M, BOUMSELL L, HANCE AJ, SOLER P, 1993. Evidence that GM-CSF regulates the distribution and differentiated state of DC/LC in human lung and lung cancers. J Clin Invest 91: 566-576.
65. THEPEN T, VAN ROOIJEN N, KRAAL G, 1989. Alveolar macrophage elimination in vivo is associated in vivo with an increase in pulmonary immune responses in mice. J Exp Med 170: 494-509.
66. THEPEN T, MCMENAMIN C, GIRN B, KRAAL G, HOLT PG, 1992. Regulation of IgE production in pre-sensitized animals: in vivo elimination of alveolar macrophages preferentially increase IgE responses to inhaled allergen. Clin Exp Allergy 22: 1107-1114.
67. THOMPSON CB, 1995. Distinct roles for the co-stimulatory ligands B7-1 and B7-2 in T helper cell differentiation. Cell 81: 979-982.
68. TUNON DE LARA JM, BRADDING P, REDINGTON AE, CHURCH MK, HOLGATE ST, 1994. Dendritic Cells in asthmatic airways express the high affinity receptor for IgE. Am J Respir Crit Care Med 149: A958 (Abstract).
69. UKKONEN P, LEWIS V, MARSCH M, HELENIUS A, MELLMAN I, 1986. Transport of macrophage Fc receptors and Fc receptor bound ligands to lysosomes. J Exp Med 163: 952-971.