Delineation by use of specific monoclonal antibodies of the T-cell receptor and major histocompatibility complex interaction sites on the superantigen toxic shock syndrome toxin 1

Infection and Immunity

Volumn 64, Issue 4, 1996, Pages 1133-1139

  Shimonkevitz, Richard ^a,d   Boen, Eric ^a   Malmstrom, Sharon ^a   Brown, Eric ^a   Hurley, J Michael ^b   Kotzin, Brian L ^b,c   Matsumura, Masazumi ^a  

^a GILEAD SCIENCES   (United States)

^b NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^c UNIVERSITY OF COLORADO   (United States)

^d Rocky Mountain MS Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HLA DR ANTIGEN; MONOCLONAL ANTIBODY; STAPHYLOCOCCUS TOXIN;

ANIMAL CELL; ANTIBODY SPECIFICITY; ANTIGEN BINDING; ARTICLE; BINDING SITE; CELL PROLIFERATION; CRYSTAL STRUCTURE; HYBRIDOMA; IMMUNOMODULATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; TOXIC SHOCK SYNDROME;

EID: 0029879161     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.64.4.1133-1139.1996     Document Type: Article

References (27)

1. Abe, J., B. L. Kotzin, C. Meissner, M. E. Melish, M. Takahashi, D. Fulton, F. Romagne, B. Malissen, and D. Y. Leung. 1993 Characterization of T cell repertoire changes in acute Kawasaki disease. J Exp Med 177:791-796.
2. Acharya, K. R., E. F. Passalacqua, E. Y. Jones, K. Harlos, D. I. Stuart, R. D. Brehm, and H. S. Tranter. 1994. Structural basis of superantigen action inferred from crystal structure of toxic shock syndrome toxin-1. Nature (London) 367:94-97.
3. Blanco, L., E. M. Choi, K. Connolly, M. R. Thompson, and P. F. Bonventre. 1990 Mutants of staphylococcal toxic shock syndrome toxin 1: mitogenicity and recognition by a neutralizing antibody. Infect Immun. 58:3020-3028
4. Blomster-Hautamaa, D. A., R. P. Novick, and P. M. Schlievert. 1986. Localization of biologic functions of toxic shock syndrome toxin-1 by use of monoclonal antibodies and cyanogen bromide fragments. J Immunol. 137:3572-3576.
5. Bohach, G. A., D. J. Fast, R. D. Nelson, and P. M. Schlievert. 1990. Staphylococcal and streptococcal pyrogenic toxins involved in toxic shock syndrome and related illnesses. Crit. Rev. Microbiol. 17:251-272.
6. Bonventre, P. F., H. Heeg, C. Cullen, and C.-J. Lian. 1993. Toxicity of recombinant toxic shock syndrome toxin 1 and mutant toxins produced by Staphylococcus aureus in a rabbit infection model of toxic shock syndrome Infect. Immun. 61:793-799.
7. Bonventre, P. F., M. R. Thompson, L. E. Adinolfi, Z. A. Gillis, and J. Parsonnet. 1988. Neutralization of toxic shock toxin-1 by monoclonal antibodies in vitro and in vivo. Infect. Immun. 56:135-141.
8. Chapes, S. K., S. M. Hoynowski, K. M. Woods, J. W. Armstrong, A. A. Beharka, and J. J. Iandolo. 1993. Staphylococcus-mediated T-cell activation and spontaneous natural killer activity in the absence of major histocompatibility complex class II molecules. Infect. Immun. 61:4013-4016.
9. Choi, Y., J. W. Kappler, and P. Marrack. 1991. A superantigen encoded in the open reading frame of the 3′ long terminal repeat of mouse mammary tumor virus. Nature (London) 350:203-207.
10. Cullen, C., H. Heeg, L. Blanco, P. Bonventre, and E. Choi. 1993. A mutation in TSST-1 which dissociates T cell stimulatory activity from MHC class II binding. J. Immunol 150:153A.
11. Deresiewicz, R. L., J. H. Woo, M. Chan, R. W. Finberg, and D. L. Kasper. 1994. Mutations affecting the biological activity of toxic shock syndrome toxin-1. Biochemistry 33:12844-12851.
12. Hamad, A. R. A., A. Herman, P. Marrack, and J. W. Kappler. 1994. Monoclonal antibodies defining functional sites on the toxin superantigen staphylococcal enterotoxin B J. Exp. Med 180:615-621.
13. Hurley, J. M., R. Shimonkevitz, A. Hanagan, K. Enney, E. Boen, S. Malmstrom, B. L. Kotzin, and M. Matsumura. 1995. Identification of class II MHC and T cell receptor binding sites in the superantigen toxic shock syndrome toxin-1. J. Exp. Med. 181:2229-2235.
14. Kappler, J. W., A. Herman, J. Clements, and P. Marrack. 1992. Mutations defining functional regions of the superantigen staphylococcal enterotoxin B. J. Exp. Med. 175:387-396.
15. Kappler, J. W., B. Skidmore, J. White, and P. Marrack. 1981. Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition J. Exp. Med. 153:1198-1214
16. Kim, J., R. G. Urban, J. L. Strominger, and D. C. Wiley. 1994. Toxic shock syndrome toxin-1 complexed with class II major histocompatibility molecule HLA-DR1 Science 266:1870-1874.
17. Kokan-Moore, N. P., and M. S. Bergdoll. 1989. Determination of biologically active region in toxic shock syndrome toxin 1. Rev. Infect. Dis. 11:S125-S129.
18. Kotzin, B. L., D. Y. M. Leung, J. Kappler, and P. Marrack. 1993. Superantigens and their potential role in human disease. Adv. Immunol 54:99-166.
19. Landegren, U. 1984. Measurement of cell numbers by means of the endogenous enzyme hexoseaminidase Applications to the detection of lymphokines and cell surface antigens. J Immunol. Methods 67:379-385.
20. Leung, D. Y. M., R. C. Giorno, L. V. Kazemi, P. A. Flynn, and J. B. Busse. 1995. Evidence for superantigen involvement in cardiovascular injury due to Kawasaki syndrome J. Immunol. 155:5018-5021.
21. Leung, D. Y. M., H. C. Meissner, D. R. Fulton, D. L. Murray, B. L. Kotzin, and P. M. Schlievert. 1993. Isolation of a novel strain of toxic shock syndrome toxin-secreting Staphylococcus aureus from patients with Kawasaki syndrome. Lancet 342:1385-1388
22. Melish, M. E., J. Parsonett, and N. Marchette. 1994 Kawasaki syndrome (KS) is not caused by toxic shock syndrome toxin-1 (TSST-1)+ staphylococci Pediatr. Res. 35:187A.
23. Melish, M., R. Shimonkevitz, J. Bill, B. Kotzin, and N. Marchette. 1994 Search for a superantigen etiology of Kawasaki syndrome (KS). Pediatr. Res. 35:187A.
24. Murray, D. L., G. S. Prasad, C. A. Earhart, B. A. B. Leonard, B. N. Kreiswirth, R. P. Novick, D. H. Ohlendorf, and P. M. Schlievert. 1994. Immunobiologic and biochemical properties of mutants of toxic shock syndrome toxin-1. J. Immunol 152:87-95
25. Pietra, B. A., J. De Inocencio, E. H. Giannini, and R. Hirsch. 1994. TCR Vβ family repertoire and T cell activation markers in Kawasaki disease. J. Immunol. 153:1881-1888
26. Prasad, G. S., C. A. Earhart, D. L. Murray, R. P. Novick, P. M. Schlievert, and D. H. Ohlendorf. 1993 Structure of toxic shock syndrome toxin Bio chemistry 32:13761-13766.
27. Todd, J. K. 1988 Toxic shock syndrome Clin. Microbiol Rev. 1:432-446.