Therapeutic effects of estradiol benzoate on development of collagen-induced arthritis (CIA) in the Lewis rat are mediated via suppression of the humoral response against denatured collagen type II (CII)

Clinical and Experimental Immunology

Volumn 103, Issue 3, 1996, Pages 376-383

  Waksman, Y ^a   Hod, I ^a   Friedman, A ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Anti collagen antibodies; Collagen induced arthritis; Sex hormones

Indexed keywords

COLLAGEN ANTIBODY; COLLAGEN TYPE 2; ESTRADIOL BENZOATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ARTHRITIS; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNOMODULATION; INTRAMUSCULAR DRUG ADMINISTRATION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIBODY FORMATION; ANTIBODY SPECIFICITY; ARTHRITIS, EXPERIMENTAL; COLLAGEN; ESTRADIOL; FEMALE; PROTEIN DENATURATION; RATS; RATS, INBRED LEW;

EID: 0029879050     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2249.1996.tb08290.x     Document Type: Article

References (47)

1. Grossman C. Possible underlying mechanisms of sexual dimorphism in the immne response. J Steroid Biochem 1989; 34:241-52.
2. Schuurs AHWM, Verheul HAM. Effect of gender and sex steroids on the immune response. J Steroid Biochem 1990; 35:157-72.
3. Nelson JL, Steinberg AD. Sex steroids, autoimmunity and autoimmune diseases. In: Berczi I, Kovack K, eds. Hormones and immunity. Lancaster: MTP press, 1987: 93-119.
4. Silver RM, Branch DW. Autoimmune diseases in pregnancy. Bailliers Clin Obstet Gynaecol 1992; 6:565-600.
5. Vandenbroucke JP, Witteman JCM, Valkenburg HA et al. Non-contraceptive hormones and rheumatoid arthritis in perimenopausal and postmenopausal women. J Am Med Ass 1986; 255: 1299-303.
6. Hazes JMW, Dukmans BAC, Vandenbroucke JP, Cats A. Reduction of the risk of rheumatoid arthritis among women who take the oral contraceptives. Arthritis Rheum 1990; 33:173-9.
7. Bijlsma JW, Van den Brink HR. Estrogen and rheumatoid arthritis. AmJ Reprod Immunol 1992; 28:231-4.
8. Hall GM, Daniels M, Huskisson EC, Spector TD. A randomized controlled trial on the effect of hormone replacement therapy on disease activity in postmenopausal rheumatoid arthritis. Ann Rheum Dis 1994; 53:112-6.
9. Courtenay JS, Dalman MJ, Dayan AD, Martin A, Mosedale B. Immunization against heterologous type II collagen induced arthritis in mice. Nature 1980; 2843:666-8.
10. Trentham DE, Townes AS, Kang AH. Autoimmunity to type II collagen: an experimental model of arthrits. J Exp Med 1977; 146: 857-68.
11. Stuart JM, Cremer MA, Townes AS, Kang AH, Type II collagen-induced arthritis in rats: passive transfer with serum and evidence that IgG anticollagen antibodies can cause arthritis. J Exp Med 1982; 155:1-16.
12. Trentham DE. Collagen arthritis as a relevant model for rheumatoid arthritis: evidence pro and con. Arthritis Rheum 1982; 25: 911-6.
13. Ridge SC, Oronsky AL, Kerwar SS. Type II collagen-induced arthritis in rats. Methods Enzymol 1988; 162:355-60.
14. Holmdahl R, Jansson L, Anderson M. Female sex hormones suppress the development of collagen induced arthritis in mice. Arthritis Rheum 1986; 29:1501-9.
15. Larrson P, Holmdahl R. Oestrogen-induced suppression of collagen induced arthritis. II. Treatment of rats suppresses development of arthritis but does not effect anti-CII humoral response. Scand J Immunol 1987; 26:579-83.
16. + T lymphocytes. Scand J Immunol 1989; 30:741-7.
17. Mattson R, Mattson A, Holmdahl R, Whyte A, Rook GAW. Maintained pregnancy levels of oestrogen afford complete protection from post partum exacerbation of collagen-induced arthritis. Clin Exp Immunol 1991; 85:41-47.
18. Klareskog L, Holmdahl E, Larsson R, Wigzell H. Role of T lymphocytes in collagen II induced arthritis in rats. Clin Exp Immunol 1983; 51:117-25.
19. Brahn E, Trentham DE. Effect of anti-thymocye serum on collagen arthritis in rats: evidence that T cells are involved in its pathogenesis. Cell Immunol 1984; 86:421-8.
20. Seki N, Sudo Y, Yoshioka T et al. Type II collagen-induced murine arthritis. 1. Induction and perpetuation of arthritis require synergy between humoral and cell mediated immunity. J Immunol 1988; 140:1477-84.
21. Takagishi H, Kaibara N, Hotokebuchi T, Arita C, Morinaya M, Arai K. Serum transfer of collagen induced arthritis in congenitally athymic nude rats. J Immunol 1985; 134:3864-7.
22. Stuart JM, Tomoda K, Yoo TJ, Kang AV. Serum transfer of collagen induced arthritis. II. Identification and localization of autoantibodies to type II collagen in donor and recipient rats. Arthritis Rheum 1983; 26:1237-44.
23. Ofosu-Appiah WA, Morgan K, Holt PJL. Native type-II collagen induced arthritis in the rat. Studies of the humoral response to collagen at the cellular level. J Rheumatol 1984; 11:432-7.
24. Michaeli D, Funberg HH. The incidence and antigenic specificity of antibodies directed against denatured human collagen in rheumatoid arthritis. Clin Immunol Immunopathol 1974; 2:153-9.
25. Rosenberg AM, Hunt DWC, Petty RE. Antibodies to native and denatured type II collagen in children with rheumatoid diseases. J Rheumatol 1984; 11:425-31.
26. Rowley MJ, Williamson DJ, Mackay IR. Evidence for local synthesis of antibodies to denatured collagen in the synovium in rheumatoid arthritis. Arthritis Rheum 1987; 30:1420-5.
27. Collins J, Morgan K, Clague RB, Brenchley PEC, Holt PJL, IgG subclass distribution of anti-native type II collagen and anti-denatured type II collagen antibodies in patients with rheumatoid arthritis. J Rheumatol 1988; 15:770-4.
28. Ferriss J, Cooper S, Roessner K, Hochberg M. Antibodies to denatured type II collagen in rheumatoid arthritis: negative association with IgM rheumatoid factor. J Rheumatol 1990; 17:880-4.
29. Dodge GR, Poole AR. Immunohistochemical detection and immunochemical analysis of type II collagen degradation in human normal, rheumatoid and osteoarthritic articular cartilages and in explants of bovine articular cartilage cultured with interleukin-1. Clin Invest 1989; 83:647-61.
30. Dodge GR, Pidoux I, Poole AR. The degradation of type II collagen in rheumatoid arthritis: an immunoelectron microscopic study. Matrix 1991; 11:330-8.
31. t'Hart BA, Bakker NPM, Jonker M, Bontrop RE. Resistance to collagen induced arthritis in rats and Rhesus monkeys after immunization with attenuated type II collagen. Eur J Immunol 1993; 23:1588-94.
32. Miller EJ. Structural studies on cartilage employing limited cleavage and solubilization with pepsin. Biochem 1972; 11:4901-9.
33. Miller EJ, Rhodes RK. Preparation and characterization of the different types of collagen. Methods Enzymol 1982; 82:33-64.
34. Kaibara N, Hotokebuchi T, Takagishi K, Katsuki I. Paradoxical effects of cyclosporin A on collagen induced arthritis in rats. J Exp Med 1983; 158:2007-15.
35. McKinney MM, Parkinson A. A simple, non-chromatographic procedure to purify imunoglobulins from serum and ascites fluid. J Immunol Methods 1987; 96:271-8.
36. Toivanen P, Maatta K, Suolanen R, Tykkylainen R. Effect of estrone and progesterone an adjuvant arthritis in rats. Med Pharmacol Exp 1967; 17:33-42.
37. Mueller MN, Kappas A. Estradiol pharmacology. II. Suppression of experimental immune polyarthritis. Proc Soc Exp Biol Med 1972; 117:845-7.
38. Holmdahl R, Jansson L, Meyerson B, Klareskog L. Oestrogen induced suppression of collagen induced arthritis: I. Long term estradiol treatment of DBA/1 mice reduced severity and incidence of arthritis and decreased anti-collagen immune response. Clin Exp Immunol 1987; 70:372-8.
39. Okayasu I, Kong YM, Rose NR. Effect of castration and sex hormones on experimental autoimmune thyroiditis. Clin Immunol Immunopathol 1981; 20:240-5.
40. Strigard K, Holmdahl R, Olsson T. Oestrogen treatment reduces disease duration of experimental allergic neuritis in rats and suppresses T cell response to myelin. Acta Neurol Scand 1990; 81: 436-42.
41. Carlsten H, Nilsson N, Jonsson R, Backman K, Holmdahl R, Tarkowsky A. Estrogen accelerates immune complex glomerulonephritis but ameliorates T-cell mediated vasculitis and sialadenitis in autoimmune MRL lpr/lpr mice. Cell Immunol 1992; 144: 190-202.
42. Carlsten H, Tarkowsky A. Histocompatibility complex gene production and exposure to oestrogens: two independent disease acceleration functions in murine lupus. Scand J Immunol 1993; 38:341-7.
43. Ratkay LG, Zhang D, Tonzetich J, Levy JG, Waterfield JD. Evaluation of a model of post-partum arthritis and the role of oestrogen in prevention of MRL-lpr/lpr associated rheumatic conditions. Clin Exp Immunol 1994; 98:52-59.
44. Cremer MA, Terato K, Watson WC, Griffith MA, Townes AS, Kang AH. Collagen induced arthritis in rats. Examination of the epitope specificities of circulating and cartilage-bound antibodies produced by outbred and inbred rats using CNBr-derived peptides purified from heterologous and homologous CII. J Immunol 1992; 149:1045-53.
45. Mo JA, Bona CA, Holmdahl R. Variable region gene selection of immunoglobulin G-expressing B cells with specificity for a defined epilope on type II collagen. Eur J Immunol 1993; 23:2503-10.
46. q mice. J Immunol 1994; 152:3088-97.
47. Friedman A, Al-Sabbagh A, Santos LMB et al. Oral tolerance: a biologically relevant pathway to generate peripheral tolerance against external and self antigens. In: Granstein RD, ed. Mechanisms of immune regulation. Basel: Karger, 1994: 259-80.