The synthesis of the novel adenosine agonists, exo- and endo- N6-(5,6-epoxynorborn-2-yl)adenosine

Tetrahedron

Volumn 52, Issue 13, 1996, Pages 4735-4744

  Scammells, Peter J ^a   Baker, Stephen P ^b   Bellardinelli, Luiz ^b   Olsson, Ray A ^c   Russell, Richard A ^a   Wright, Denis M J ^a  

^a DEAKIN UNIVERSITY   (Australia)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 N (5,6 EPOXYNORBORN 2 YL)ADENOSINE; 6 N CYCLOPENTYLADENOSINE; ADENOSINE A1 RECEPTOR; ADENOSINE DERIVATIVE; CYCLIC AMP; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; STEREOCHEMISTRY;

EID: 0029878351     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4020(96)00144-5     Document Type: Article

References (16)

1. Jacobson, K.A.; van Galen, P.J.M., Williams, M. J. Med. Chem. 1992, 35, 407-422.
2. Scammells, P.J.; Baker, S.P.; Olsson; Belardinelli, L. US Patent 08/144 459, 1994.
3. Dooley, M.J.; Quinn, R.J. J. Med. Chem. 1992, 35, 211-216.
4. Peet, N.P.; Lentz, N.L.; Meng, E.C.; Dudley, M.W.; Ogden, A.M.; Demeter, D.A.; Weintraub, H.J.; Bey, P. J. Med. Chem. 1990, 33, 3127-3130.
5. Fleysher, M.H. J. Med. Chem. 1972, 15, 187-191.
6. Diveley, W.R.; Buntin, G.A.; Lohr, A.D., J. Org. Chem. 1969, 34, 616-624.
7. Stille, J.K.; Sannes, K.N. J. Am. Chem. Soc. 1972, 94, 8494-8496.
8. Poll, T.; Sobazak, A.; Hartmann, H.; Helmchen, G., Tetrahedron Lett. 1985, 26, 3095-3098.
9. Poll, T.; Abdel Hady, F.; Karge, R.; Linz, G.; Helmchen, G., Tetrahedron Lett. 1989, 30, 5595-5598.
10. Parham, W.E.; Hunter, W.T.; Hanson, J. Am. Chem. Soc. 1951, 73, 5068-5070.
11. Pfister, J.R.; Wymann, W.E. Synthesis 1983, 38.
12. Stevens, M.A.; Smith, H.W.; Brown, G.B. J. Am. Chem. Soc. 1959, 81, 1734-1738.
13. Fischer, B.; Boyer, J.L.; Hoyle, C.H.; Ziganshin, A.U.; Brizzolara, A.L.; Knight, G.E.; Zimmet, J.; Burnstock, G.; Harden, T.K.; Jacobsen, K.A. J. Med. Chem. 1993, 36, 3937-3946.
14. Adam, W.A.; Bialas, J.; Hadjiarapoglou, L.; Chem. Ber. 1991, 124, 2377.
15. Lowry, O.H.; Rosebrough, N.J.; Farr, A.L.; Randall, R.J. J. Biol. Chem. 1951, 193, 265-275.
16. Standifer, K.M.; Pitha, J.; Baker, S.P. Naunyn-Schmiedeberg's Arch. Pharmacol. 1989, 339, 129-137.