-
1
-
-
0011173091
-
Alterations in DNA polymerases-α, -β , and -δ in human brain tumor cells after glutathione (GSH) depletion
-
Ali-Osman F, Rairkar A (1992) Alterations in DNA polymerases-α, -β , and -δ in human brain tumor cells after glutathione (GSH) depletion. Proc Am Assoc Cancer Res 33: 497
-
(1992)
Proc Am Assoc Cancer Res
, vol.33
, pp. 497
-
-
Ali-Osman, F.1
Rairkar, A.2
-
2
-
-
0028218705
-
Enhanced repair of a cisplatin-damaged reporter chloramphenicol-O-acetyl-transferase gene and altered activities of DNA polymerase alpha, beta and DNA ligase in cells of malignant glioma following in vivo cisplatin therapy
-
Ali-Osman F, Berger MS, Rairkar A, Stein DE (1994) Enhanced repair of a cisplatin-damaged reporter chloramphenicol-O-acetyl-transferase gene and altered activities of DNA polymerase alpha, beta and DNA ligase in cells of malignant glioma following in vivo cisplatin therapy. J Cell Biochem 54: 11-19
-
(1994)
J Cell Biochem
, vol.54
, pp. 11-19
-
-
Ali-Osman, F.1
Berger, M.S.2
Rairkar, A.3
Stein, D.E.4
-
3
-
-
0024466138
-
Enhanced DNA cross-link removal: The apparent mechanism of resistance in a clinically relevant melphalan-resistant human breast cancer cell line
-
Batist G, Torres-Garcia S, Demuys, JM, Greene D, Lehnert S, Rochon M, Panasci L (1989) Enhanced DNA cross-link removal: the apparent mechanism of resistance in a clinically relevant melphalan-resistant human breast cancer cell line. Mol Pharmacol 36: 224-230
-
(1989)
Mol Pharmacol
, vol.36
, pp. 224-230
-
-
Batist, G.1
Torres-Garcia, S.2
Demuys, J.M.3
Greene, D.4
Lehnert, S.5
Rochon, M.6
Panasci, L.7
-
4
-
-
0025047842
-
Clinical applications of 3′-azido-2′,3′-dideoxythymidine (AZT) and related dideoxynucleosides
-
Broder S (1990) Clinical applications of 3′-azido-2′,3′-dideoxythymidine (AZT) and related dideoxynucleosides. Med Res Rev 10: 419-439
-
(1990)
Med Res Rev
, vol.10
, pp. 419-439
-
-
Broder, S.1
-
5
-
-
0019780712
-
Growth and chemotherapeutic response in athymic mice of tumor arising from human glioma-derived cell line
-
Bullard DE, Schold SC Jr, Bigner SH, Bigner DD (1981) Growth and chemotherapeutic response in athymic mice of tumor arising from human glioma-derived cell line. J Neuropathol Exp Neurol 40: 410-427
-
(1981)
J Neuropathol Exp Neurol
, vol.40
, pp. 410-427
-
-
Bullard, D.E.1
Schold Jr., S.C.2
Bigner, S.H.3
Bigner, D.D.4
-
6
-
-
8944257094
-
-
National Cancer Institute, Bethesda
-
Dideoxycytidine, NSC 606170 (1994) National Cancer Institute, Bethesda
-
(1994)
Dideoxycytidine, NSC 606170
-
-
-
7
-
-
0019381263
-
Selection and characterization of Chinese hamster ovary cell mutants resistant to melphalan (L-phenylalanine mustard)
-
Elliott EM, Ling V (1981) Selection and characterization of Chinese hamster ovary cell mutants resistant to melphalan (L-phenylalanine mustard). Cancer Res 41: 393-400
-
(1981)
Cancer Res
, vol.41
, pp. 393-400
-
-
Elliott, E.M.1
Ling, V.2
-
8
-
-
0022647286
-
Chemotherapy of subcutaneous and intracranial human medulloblastoma xenografts in athymic nude mice
-
Friedman HS, Schold SC Jr, Bigner DD (1986) Chemotherapy of subcutaneous and intracranial human medulloblastoma xenografts in athymic nude mice. Cancer Res 46: 224-248
-
(1986)
Cancer Res
, vol.46
, pp. 224-248
-
-
Friedman, H.S.1
Schold Jr., S.C.2
Bigner, D.D.3
-
9
-
-
0023685313
-
Melphalan transport, glutathione levels, and glutathione-S-transferase activity in human medulloblastoma
-
Friedman HS, Skapek SX, Colvin OM, Elion GB, Blum MR, Savina PM, Hilton J, Schold SC Jr, Kurtzberg J, Bigner DD (1988) Melphalan transport, glutathione levels, and glutathione-S-transferase activity in human medulloblastoma. Cancer Res 48: 5397-5402
-
(1988)
Cancer Res
, vol.48
, pp. 5397-5402
-
-
Friedman, H.S.1
Skapek, S.X.2
Colvin, O.M.3
Elion, G.B.4
Blum, M.R.5
Savina, P.M.6
Hilton, J.7
Schold Jr., S.C.8
Kurtzberg, J.9
Bigner, D.D.10
-
10
-
-
0024315137
-
Phase II treatment of medulloblastoma and pineoblastoma with melphalan: Clinical therapy based on experimental models of human medulloblastoma
-
Friedman HS, Schold SC, Mahaley MS, Colvin OM, Oakes WJ, Vick UA, Burger PC, Bigner SH, Borowitz M, Halperin EC, Djang W, Falletta JM, DeLong R, Garvin JH, DeVivo DC, Norris D, Golembe B, Winter J, Bodziner RA, Sipahi H, Bigner DD (1989) Phase II treatment of medulloblastoma and pineoblastoma with melphalan: clinical therapy based on experimental models of human medulloblastoma. J Clin Oncol 7: 904-911
-
(1989)
J Clin Oncol
, vol.7
, pp. 904-911
-
-
Friedman, H.S.1
Schold, S.C.2
Mahaley, M.S.3
Colvin, O.M.4
Oakes, W.J.5
Vick, U.A.6
Burger, P.C.7
Bigner, S.H.8
Borowitz, M.9
Halperin, E.C.10
Djang, W.11
Falletta, J.M.12
DeLong, R.13
Garvin, J.H.14
DeVivo, D.C.15
Norris, D.16
Golembe, B.17
Winter, J.18
Bodziner, R.A.19
Sipahi, H.20
Bigner, D.D.21
more..
-
11
-
-
0028228297
-
Elevated DNA polymerase α, DNA polymerase β, and DNA topoisomerase II in a melphalan-resistant rhabdomyosarcoma xenograft that is cross-resistant to nitrosoureas and topotecan
-
Friedman HS, Dolan ME, Kaufmann O, Colvin OM, Griffith OW, Moschel RC, Schold SC Jr, Bigner DD, Ali-Osman F (1994) Elevated DNA polymerase α, DNA polymerase β, and DNA topoisomerase II in a melphalan-resistant rhabdomyosarcoma xenograft that is cross-resistant to nitrosoureas and topotecan. Cancer Res 54: 3487-3493
-
(1994)
Cancer Res
, vol.54
, pp. 3487-3493
-
-
Friedman, H.S.1
Dolan, M.E.2
Kaufmann, O.3
Colvin, O.M.4
Griffith, O.W.5
Moschel, R.C.6
Schold Jr., S.C.7
Bigner, D.D.8
Ali-Osman, F.9
-
12
-
-
0020480247
-
DNA polymerase d: One polypeptide, two activities
-
Goscin LP, Byrnes JJ (1982) DNA polymerase d: one polypeptide, two activities. Biochemistry 21: 2513-2518
-
(1982)
Biochemistry
, vol.21
, pp. 2513-2518
-
-
Goscin, L.P.1
Byrnes, J.J.2
-
13
-
-
8944263056
-
Potentiation of melphalan cytotoxicity in human ovarian cancer cell lines by glutathione depletion
-
Green JA, Vistica DT, Young RC, Hamilton TC, Rogan AM, Ozols RF (1987) Potentiation of melphalan cytotoxicity in human ovarian cancer cell lines by glutathione depletion. Cancer Res 47: 1593-1597
-
(1987)
Cancer Res
, vol.47
, pp. 1593-1597
-
-
Green, J.A.1
Vistica, D.T.2
Young, R.C.3
Hamilton, T.C.4
Rogan, A.M.5
Ozols, R.F.6
-
14
-
-
0023832837
-
Phase II testing of melphalan in children with newly diagnosed rhabdomyosarcoma: A model for anticancer drug development
-
Horowitz ME, Etcubanas E, Chistenson ML, Houghton PJ (1988) Phase II testing of melphalan in children with newly diagnosed rhabdomyosarcoma: a model for anticancer drug development. J Clin Oncol 6: 308-314
-
(1988)
J Clin Oncol
, vol.6
, pp. 308-314
-
-
Horowitz, M.E.1
Etcubanas, E.2
Chistenson, M.L.3
Houghton, P.J.4
-
15
-
-
0019435919
-
New views of the biochemistry of eukaryotic DNA replication revealed by aphidicolin, an unusual inhibitor of DNA polymerase alpha
-
Huberman JA (1981) New views of the biochemistry of eukaryotic DNA replication revealed by aphidicolin, an unusual inhibitor of DNA polymerase alpha. Cell 23: 647-648
-
(1981)
Cell
, vol.23
, pp. 647-648
-
-
Huberman, J.A.1
-
16
-
-
0018118897
-
Aphidicolin prevents mitotic cell division by interfering with the activity of DNA polymerase-alpha
-
Ikegami S, Taguchi T, Ohashi M, Oguro M, Nagano H, Mano Y (1978) Aphidicolin prevents mitotic cell division by interfering with the activity of DNA polymerase-alpha. Nature 275: 458-460
-
(1978)
Nature
, vol.275
, pp. 458-460
-
-
Ikegami, S.1
Taguchi, T.2
Ohashi, M.3
Oguro, M.4
Nagano, H.5
Mano, Y.6
-
17
-
-
0025151772
-
The effect of DNA polymerase inhibitors on the cytotoxicity of cisplatin in human ovarian carcinoma cells
-
Katz EJ, Andrews PA, Howell SB (1990) The effect of DNA polymerase inhibitors on the cytotoxicity of cisplatin in human ovarian carcinoma cells. Cancer Commun 2: 159-164
-
(1990)
Cancer Commun
, vol.2
, pp. 159-164
-
-
Katz, E.J.1
Andrews, P.A.2
Howell, S.B.3
-
18
-
-
0023124018
-
Chemosensitization of L-phenylalanine mustard by the thiol-modulating agent butathione sulfoximine
-
Kramer RA, Greene K, Ahmad S Vistica DT (1987) Chemosensitization of L-phenylalanine mustard by the thiol-modulating agent butathione sulfoximine. Cancer Res 47: 1593-1597
-
(1987)
Cancer Res
, vol.47
, pp. 1593-1597
-
-
Kramer, R.A.1
Greene, K.2
Ahmad, S.3
Vistica, D.T.4
-
19
-
-
0024238957
-
Enhanced DNA repair and resistance to cisplatin in human ovarian cancer
-
Lai GM, Ozols RF, Smyth JF, Young RC, Hamilton TC (1988) Enhanced DNA repair and resistance to cisplatin in human ovarian cancer. Biochem Pharmacol 37: 4597-4600
-
(1988)
Biochem Pharmacol
, vol.37
, pp. 4597-4600
-
-
Lai, G.M.1
Ozols, R.F.2
Smyth, J.F.3
Young, R.C.4
Hamilton, T.C.5
-
20
-
-
0026385673
-
Therapeutic analysis of melphalan-resistant human rhabdomyosarcoma xenograft TE-671 MR
-
Lilley ER, Elion GB, Dewhirst MW, Schold SC Jr, Blum MR, Savina PM, Laskowitz DT, Bigner DD, Friedman HS (1991) Therapeutic analysis of melphalan-resistant human rhabdomyosarcoma xenograft TE-671 MR. Cancer Res 51: 3906-3909
-
(1991)
Cancer Res
, vol.51
, pp. 3906-3909
-
-
Lilley, E.R.1
Elion, G.B.2
Dewhirst, M.W.3
Schold Jr., S.C.4
Blum, M.R.5
Savina, P.M.6
Laskowitz, D.T.7
Bigner, D.D.8
Friedman, H.S.9
-
21
-
-
0023750017
-
Increased DNA repair as a mechanism of acquired resistance to cis-diamminedichloroplatinum (II) in human ovarian cancer cell lines
-
Masuda H, Ozols RF, Lai G-M, Fojo A, Rothenberg M, Hamilton TC (1988) Increased DNA repair as a mechanism of acquired resistance to cis-diamminedichloroplatinum (II) in human ovarian cancer cell lines. Cancer Res 48: 5713-5716
-
(1988)
Cancer Res
, vol.48
, pp. 5713-5716
-
-
Masuda, H.1
Ozols, R.F.2
Lai, G.-M.3
Fojo, A.4
Rothenberg, M.5
Hamilton, T.C.6
-
22
-
-
0017647702
-
Establishment of a human medulloblastoma cell line
-
McAllister RM, Isaacs H, Rongey R, Peer M, Au W, Soulcup SW, Gardner MB (1977) Establishment of a human medulloblastoma cell line. Int J Cancer 20: 206-212
-
(1977)
Int J Cancer
, vol.20
, pp. 206-212
-
-
McAllister, R.M.1
Isaacs, H.2
Rongey, R.3
Peer, M.4
Au, W.5
Soulcup, S.W.6
Gardner, M.B.7
-
23
-
-
0027958095
-
Antitumor activity and biochemical effects of aphidicolin glycinate (NSC 303812) alone and in combination with cisplatin in vivo
-
O'Dwyer PJ, Moyer JD, Suffness M, Harrison SD Jr, Cyrsyk R, Hamilton TC, Plowman J (1994) Antitumor activity and biochemical effects of aphidicolin glycinate (NSC 303812) alone and in combination with cisplatin in vivo. Cancer Res 54: 724-729
-
(1994)
Cancer Res
, vol.54
, pp. 724-729
-
-
O'Dwyer, P.J.1
Moyer, J.D.2
Suffness, M.3
Harrison Jr., S.D.4
Cyrsyk, R.5
Hamilton, T.C.6
Plowman, J.7
-
24
-
-
0018499594
-
The mode of inhibitory action by aphidicolin on eukaryotic DNA polymerase a
-
Oguru M, Suzuki-Hori C, Nagano H, Mano Y, Ikegami S (1979) The mode of inhibitory action by aphidicolin on eukaryotic DNA polymerase a. Eur J Biochem 97: 603-607
-
(1979)
Eur J Biochem
, vol.97
, pp. 603-607
-
-
Oguru, M.1
Suzuki-Hori, C.2
Nagano, H.3
Mano, Y.4
Ikegami, S.5
-
25
-
-
0024364364
-
Differential inhibitory effects of several pyrimidine 2′,3′-dideoxynucleoside 5′-triphosphates on the activities of reverse transcriptase and various cellular DNA ploymerases
-
Ono K, Nakane H, Herdewijn P, Balzarini J, Clercq E de (1989) Differential inhibitory effects of several pyrimidine 2′,3′-dideoxynucleoside 5′-triphosphates on the activities of reverse transcriptase and various cellular DNA ploymerases. Mol Pharmacol 35: 578-583
-
(1989)
Mol Pharmacol
, vol.35
, pp. 578-583
-
-
Ono, K.1
Nakane, H.2
Herdewijn, P.3
Balzarini, J.4
De Clercq, E.5
-
26
-
-
0023119841
-
Enhanced melphalan cytotoxicity in human ovarian cancer in vitro and in tumor-bearing nude mice by butathione sulfoximine depletion of glutathione
-
Ozols RF, Louis KG, Plowman J, Behens BC, Fine RL, Dykes D, Hamilton TC (1987) Enhanced melphalan cytotoxicity in human ovarian cancer in vitro and in tumor-bearing nude mice by butathione sulfoximine depletion of glutathione Biochem Pharmacol 36: 147-153
-
(1987)
Biochem Pharmacol
, vol.36
, pp. 147-153
-
-
Ozols, R.F.1
Louis, K.G.2
Plowman, J.3
Behens, B.C.4
Fine, R.L.5
Dykes, D.6
Hamilton, T.C.7
-
27
-
-
0019505057
-
Mechanism of melphalan resistance developed in vitro in human melanoma cells
-
Parsons PG, Carter FB, Morrison L, Regius M (1981) Mechanism of melphalan resistance developed in vitro in human melanoma cells. Cancer Res 41: 1525-1534
-
(1981)
Cancer Res
, vol.41
, pp. 1525-1534
-
-
Parsons, P.G.1
Carter, F.B.2
Morrison, L.3
Regius, M.4
-
28
-
-
0018649179
-
Effect of aphidicolin on viral and human DNA polymerases
-
Pedrali-Noy G, Spadari S (1979) Effect of aphidicolin on viral and human DNA polymerases. Biochem Biophys Res Commun 88: 1194-1202
-
(1979)
Biochem Biophys Res Commun
, vol.88
, pp. 1194-1202
-
-
Pedrali-Noy, G.1
Spadari, S.2
-
29
-
-
0020059019
-
High dose melphalan with autologous marrow for the treatment of advanced neuroblastoma
-
Pritchard J, McElwain TJ, Graham-Pole J (1982) High dose melphalan with autologous marrow for the treatment of advanced neuroblastoma. Br J Cancer 45: 86-93
-
(1982)
Br J Cancer
, vol.45
, pp. 86-93
-
-
Pritchard, J.1
McElwain, T.J.2
Graham-Pole, J.3
-
30
-
-
0018901475
-
Transport of melphalan by sensitive and resistant L1210 cells
-
Redwood WR, Colvin M (1980) Transport of melphalan by sensitive and resistant L1210 cells. Cancer Res 40: 1144-1149
-
(1980)
Cancer Res
, vol.40
, pp. 1144-1149
-
-
Redwood, W.R.1
Colvin, M.2
-
31
-
-
0024817998
-
Establishment of a melphalan-resistant rhabdomyosarcoma xenograft with cross-resistance to vincristine and enhanced sensitivity following buthionine sulfoximine-mediated glutathione depletion
-
Rosenberg MC, Colvin OM, Griffith OW, Bigner SH, Elion GB, Horton JK, Lilley ER, Bigner DD, Friedman HS (1989) Establishment of a melphalan-resistant rhabdomyosarcoma xenograft with cross-resistance to vincristine and enhanced sensitivity following buthionine sulfoximine-mediated glutathione depletion. Cancer Res 49: 6917-6922
-
(1989)
Cancer Res
, vol.49
, pp. 6917-6922
-
-
Rosenberg, M.C.1
Colvin, O.M.2
Griffith, O.W.3
Bigner, S.H.4
Elion, G.B.5
Horton, J.K.6
Lilley, E.R.7
Bigner, D.D.8
Friedman, H.S.9
-
32
-
-
0015441085
-
Chemotherapy of ovarian cancer. New approaches to treatment
-
Smith JP, Rutledge F, Warton JT (1975) Chemotherapy of ovarian cancer. New approaches to treatment. Cancer 30: 1565-1571
-
(1975)
Cancer
, vol.30
, pp. 1565-1571
-
-
Smith, J.P.1
Rutledge, F.2
Warton, J.T.3
-
33
-
-
0021332334
-
Reduction in cellular glutathione by butathione sulfoximine and sensitization of murine tumor cells resistant to L-phenylalanine mustard
-
Somfei-Relle S, Suzukake K, Vistica BP, Vistica DT (1984) Reduction in cellular glutathione by butathione sulfoximine and sensitization of murine tumor cells resistant to L-phenylalanine mustard. Biochem Pharmacol 32: 484
-
(1984)
Biochem Pharmacol
, vol.32
, pp. 484
-
-
Somfei-Relle, S.1
Suzukake, K.2
Vistica, B.P.3
Vistica, D.T.4
-
34
-
-
0024525035
-
Characterization of the human cell line TE-671
-
Stratton MR, Darling J, Pilkington GJ, Lanto, PL, Reeves BP, Cooper CS (1989) Characterization of the human cell line TE-671. Carcinogenesis 10: 899-905
-
(1989)
Carcinogenesis
, vol.10
, pp. 899-905
-
-
Stratton, M.R.1
Darling, J.2
Pilkington, G.J.3
Lanto, P.L.4
Reeves, B.P.5
Cooper, C.S.6
-
35
-
-
0025093198
-
Glutathione-S-transferases: Role in alkylating agent resistance and possible target for modulation chemotherapy
-
Waxman D (1990) Glutathione-S-transferases: role in alkylating agent resistance and possible target for modulation chemotherapy. Cancer Res 50: 6449-6454
-
(1990)
Cancer Res
, vol.50
, pp. 6449-6454
-
-
Waxman, D.1
-
36
-
-
0019218107
-
Chick embryo DNA polymerase B
-
Yagamuchi M, Tanabe K, Taguchi YN, Nishizawa M, Takahashi T, Matsukage A (1980) Chick embryo DNA polymerase B. J Biol Chem 255: 9942-9948
-
(1980)
J Biol Chem
, vol.255
, pp. 9942-9948
-
-
Yagamuchi, M.1
Tanabe, K.2
Taguchi, Y.N.3
Nishizawa, M.4
Takahashi, T.5
Matsukage, A.6
-
37
-
-
0019350535
-
DNA cross-linking as an indicator of sensitivity and resistance of mouse L1210 leukemia to cis-diamminedichloroplatinum (II) and phenylalanine mustard
-
Zwelling LA, Michaels S, Schwartz H, Dobson PP, Kohn KW (1981) DNA cross-linking as an indicator of sensitivity and resistance of mouse L1210 leukemia to cis-diamminedichloroplatinum (II) and phenylalanine mustard Cancer Res 41: 640-649
-
(1981)
Cancer Res
, vol.41
, pp. 640-649
-
-
Zwelling, L.A.1
Michaels, S.2
Schwartz, H.3
Dobson, P.P.4
Kohn, K.W.5
|