Identification of an osteocalcin gene promoter sequence that binds AP1

Journal of Cellular Biochemistry

Volumn 60, Issue 4, 1996, Pages 447-457

  Goldberg, Daniella ^a   Polly, Patsie ^a   Eisman, John A ^a   Morrison, Nigel A ^a  

^a ST VINCENT S HOSPITAL   (Australia)

Author keywords

AP1; DNA binding; osteoblast; osteocalcin promoter; vitamin D induction

Indexed keywords

COLECALCIFEROL; DNA BINDING PROTEIN; OSTEOCALCIN; PROTEIN C FOS;

ARTICLE; CELL DIFFERENTIATION; GENE EXPRESSION REGULATION; GROWTH REGULATION; HORMONAL REGULATION; HUMAN; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA INTERACTION; SEQUENCE ANALYSIS; TRANSCRIPTION INITIATION;

BASE SEQUENCE; CALCITRIOL; CHROMOSOME DELETION; DNA-BINDING PROTEINS; HUMANS; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDES; OSTEOCALCIN; PROMOTER REGIONS (GENETICS); SEQUENCE HOMOLOGY, NUCLEIC ACID; TRANSCRIPTION FACTOR AP-1;

EID: 0029878153     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(19960315)60:4<447::AID-JCB2>3.0.CO;2-S     Document Type: Article

References (17)

1. Banerjee C, Stein LS, van Wijnen AJ, Kovary K, Bravo R, Lian JB, Stein GS (1994): Identification of a TGFβ response element in the rat osteocalcin gene. J Bone Miner Res 9 (Suppl):161
2. Bidwell JP, van Wijnen AJ, Fey EG, Merriman H, Penman S, Stein LS, Lian JB (1994): Subnuclear distribution of the vitamin D receptor. J Cell Biochem 54:494-500.
3. Candeliere GA, Prud homme J, St-Arnaud R (1991): Differential stimulation of FOS and JUN family members by calcitriol in osteoblastic cells. Mol Endocrinol 5:1780-1788.
4. Goldberg D, Gardiner E, Morrison NA, Eisman JAE (1995a): G/C element contributes to the cell line specific expression of the proximal osteocalcin promoter. J Cell Biochem 58:499-508.
5. Goldberg D, Gardiner E, Morrison NA, Eisman JAE (1995b): The osteocalcin and collagen type I alpha 1 promoters share common basal regulatory units. DNA Cell Biol 14:519-528.
6. Jaaskelainen T, Pirskanen A, Ryhanen S, Palvimo JJ, De Luca HF, Maenpaa PH (1994): Functional interference between AP1 and the vitamin D receptor on osteocalcin gene expression in human osteosarcoma cells. Eur J Biochem 224:11-20.
7. Lian JB, Stein GS, Bortell R, Owen TA (1991): Phenotype suppression: A postulated molecular mechanism for mediating the relationship of proliferation and differentiation by Fos/Jun interactions at AP-1 sites in steroid responsive promoter elements of tissue-specific genes. J Cell Biochem 45:9-14.
8. Morrison NA, Shine J, Fragonas JC, Verkes PV, McMenemy ML, Eisman JA (1989): 1,25-dihydroxyvitamin D-responsive element and glucocorticoid repression in the osteocalcin gene. Science 246:1158-1161.
9. Owen TA, Bortell R, Shalhoub V, Heinrichs A, Stein JL, Stein GS, Lian JB (1993): Postproliferative transcription of the rat osteocalcin gene is reflected by vitamin D-responsive developmental modifications in protein-DNA interactions at basal and enhancer promoter elements. Proc Natl Acad Sci USA 90:1503-1507.
10. Owen TA, Bortell R, Yocum SA, Smock SL, Zhang M, Abate C, Shalhoub V, Aronin N, Wright KL, van Wijnen AJ (1990): Coordinate occupancy of AP-1 sites in the vitamin D-responsive and CCAAT box elements by Fos-Jun in the osteocalcin gene: Model for phenotype suppression of transcription. Proc Natl Acad Sci USA 87:9990-9994.
11. Ozono K, Lian J, Kerner SA, Scott RA, Pike JW (1990): The vitamin D-responsive element in the human osteocalcin gene. Association with a nuclear proto-oncogene enhancer. J Biol Chem 265:21881-21888.
12. Rodan GA, Noda M (1991): Gene expression in osteoblast cells. Crit Rev Eukaryot Gene Expr 1:85-98.
13. Sambucetti LC, Curran T (1986): The fos protein complex is associated with DNA in isolated nuclei and binds to DNA cellulose. Science 234:1417-1419.
14. Schrader M, Nayeri S, Kahlen JP, Muller KM, Carlberg C (1995): Natural vitamin D3 response elements formed by inverted palindromes: Polarity-directed ligand sensitivity of vitamin D3 receptor-retinoid × receptor heterodimer-mediated transactivation. Mol Cell Biol 15:1154-1161.
15. Schule R, Umesono K, Mangelsdorf DJ, Bolado J, Pike JW, Evans RM (1990): Jun-Fos and receptors for vitamins A and D recognize a common response element in the human osteocalcin gene. Cell 61:497-504.
16. Towler DA, Bennett CD, Rodan GA (1994): Activity of the rat osteocalcin basal promoter in osteoblastic cells is dependent on homeodomains and CP1 binding motifs. Mol Endocrinol 8:614-624.
17. Yang-Yen HF, Chambard JC, Sun YL, Smeal T, Schmidt TJ, Drouin J, Karin M (1990): Transcriptional interference between c-JUN binding and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction. Cell 62:1205-1215.